Gastroenterology Labs

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• Ahmet Gurakar Lab

  The Ahmet Gurakar Lab is interested in bioartificial liver dialysis systems and the application of total plasma exchange in the treatment of liver disorders.

  Research Areas: transplants, viral hepatitis, liver diseases, plasma exchange

  

  Principal Investigator

  Ahmet Gurakar, M.D.

  Department

  Medicine
  

• Alyssa Parian Lab

  The Alyssa Parian Lab works to identify early markers of dysplasia. We also study inflammatory bowel disease-associated cancers, conduct IBD clinical trials and examine IBD extraintestinal manifestations.

  Research Areas: inflammatory bowel disease, cancer, displaysia

  

  Principal Investigator

  Alyssa Parian, M.D.

  Department

  Medicine
  

• Anthony N. Kalloo Lab

  Research interests in the Anthony N. Kalloo Lab include therapeutic endoscopy, pancreatitis, sphincter of Oddi dysfunction and abdominal pain.

  Research Areas: sphincter of Oddi dysfunction, endoscopy, abdominal pain, pancreatitis

  

  Principal Investigator

  Anthony Kalloo

  Department

  Medicine
  

• Ashish Nimgoankar Lab

  The Ashish Nimgoankar Lab is interested in translational technology development and image-guided therapies.

  Research Areas: translational technology, imaging

  

  Principal Investigator

  Ashish Nimgaonkar, M.B.B.S., M.D., M.S.

  Department

  Medicine
  

• Brindusa Truta Lab

  The Brindusa Truta Lab studies inflammatory bowel diseases, specifically Crohn’s disease and ulcerative colitis. Recent studies defined factors associated with the development of Crohn's disease after ileal pouch anal anastomosis; determined the value of histology in identifying Lynch syndrome in early-onset of colorectal cancer patients; and compared the phenotype and genotype in adenomatous polyposis patients with and without a family history.

  Research Areas: inflammatory bowel disease, Crohn’s disease, ulcerative colitis

  

  Principal Investigator

  Brindusa Truta, M.D., M.A.S.

  Department

  Medicine
  

• Ellen Stein Lab

  Research interests in the Ellen Stein Lab include motility disorders and esophageal diseases such as reflux disease, achalasia, Barrett's esophagus and eosinophilic esophagitis.

  Research Areas: reflux disease, esophageal disease, achalasia, eosinophilic esophagitis, Barrett's esophagus, motility disorders

  

  Principal Investigator

  Ellen Stein

  Department

  Medicine
  

• Eun Ji Shin Lab

  Research interests in the Eun Ji Shin Lab include clinical research on obesity and the effect on GI neoplasia/malignancy.

  Research Areas: gastroenterology, neoplasms, obesity

  

  Principal Investigator

  Eun Shin, M.D.

  Department

  Medicine
  

• Florin Selaru Lab

  Research interests in the Florin Selaru Lab comprise the molecular changes associated with the transition from inflammatory states in the GI tract (colon, stomach, biliary tree) to frank cancers. In addition, our current research—funded by the AGA, FAMRI and the Broad Foundation—works to further the understanding of cancer development and progression in the gastrointestinal tract.

  Research Areas: gastroenterology, cancer, inflammation, molecular biology

  

  Principal Investigator

  Florin Selaru, M.D.

  Department

  Medicine
  Oncology
  

• Fluorescence Imaging Core

  The goal of the Fluorescence Imaging Core is to provide state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community. Services include advanced cell and tissue multicolor imaging using Zeiss LSM-510 META, including XYZT, FREP and FRET; live cell and tissue imaging using an Olympus FV1000 MP with ratiometric ionic probes; and measurements of intracellular pH (potentially other ions) on cell populations using PTI’s RatioMaster and QuantMaster spectrofluorometic systems equipped with temperature controlled perfusion chambers.

  Research Areas: imaging, light microscopy, digestive diseases

  Lab Website

  

  Principal Investigator

  Olga Kovbasnjuk

  Department

  Medicine
  

• Gerard E. Mullin Lab

  The Gerard E. Mullin Lab studies nutrition and the way that diet affects weight loss. In particular, we study how having an imbalanced gut microbiome may prevent weight loss in certain people.

  Research Areas: gut bacteria, nutrition, gut microbiota, obesity, weight loss

  

  Principal Investigator

  Gerard Mullin, M.D., M.S.

  Department

  Medicine
  

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