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Breast and Ovarian Cancer Program

The goal of the Breast and Ovarian Cancer Program is to use laboratory and clinical research to improve prevention, detection and treatment of these cancers. Researchers have found that there are many similarities in the molecular characteristics of breast and ovarian cancers. They are studying genetic, hormonal and hereditary risks factors that make some women more susceptible to breast or ovarian cancers in search of biomarkers that can, very early, indicate the presence of cancer and lead to better therapies. Exciting advances in cancer genetics (mutations to DNA), epigenetics (chemical alterations to the environment of DNA) and immune therapies—many of them made at the Kimmel Cancer Center—are guiding promising new treatments. This better understanding of the gene pathways and signals that go awry in breast and ovarian cancers allows investigators to develop precision, personalized approaches that target and interfere with cell processes that allow breast and ovarian cancers to originate, resist therapy, grow and spread.

Breast and Ovarian Cancer Program Leaders: