Cancer-fighting T cells from patients whose cancers responded to immunotherapy and from those whose tumors did not respond showed marked differences
Combination therapy could make curative surgery possible for some liver cancer patients who would normally not be considered for the surgery
Field of mathematics devoted to how information is measured, stored and transmitted uncovers possible key gene that spurs common childhood leukemia
Expands understanding of immune responses in cancer and other diseases
Engineered T cells can recognize and destroy cells with loss of one gene copy
New perspective article by Johns Hopkins researchers details theory behind physical frailty and ways to treat it
Offers potential to broadly expand the benefit of immunotherapies
Helps Guide Precision Medicine
Study adds context to limited knowledge of the disease
Mechanisms of age-related resistance revealed as new targets for treatment
Sessions will explore important topics related to sex and intimacy, clinical trials, the impact on mental health, and prevention and early detection
Experiments could lead to clinical trials of the drug, which already are FDA-approved
Current guidelines support first screening at age 50
Results show the liquid biopsy test could safely be incorporated into routine clinical care in combination with conventional screening
Immune “checkpoint” inhibitor treatment found useful against Merkel cell carcinoma in multicenter clinical trial
Researchers say findings support use in clinical trials
Findings from medical records study could help doctors and patients make more informed treatment decisions
Multi-omic investigations further demonstrates the complexity of the disease
Clearer understanding of lower cell replication rates in old age may have implications for preventing cancer and slowing aging
New molecular insights could mean more accurate prognoses and better selection of therapies
Researchers envision a patient-specific ‘oncology diet’ to exploit the weakness
Work with cultured cell line models offers potential new insights to melanoma progression via gene transcript stability and decay
Study reveals that E-cadherin, a molecule that allows cells to stick to each other, promotes metastasis in the most common type of breast cancer
Findings might help predict who will react poorly to certain therapies
Researchers identify key molecules for perineural invasion, a hallmark of pancreatic and other cancers
Study adds to research promoting careful antibiotic stewardship
Two FDA-approved drugs significantly extend survival time in mouse model of deadly gynecologic disease
Novel technology based on epigenetic alterations could shorten wait for a definitive diagnosis in resource-poor settings
Some deadly ovarian cancers arise from lesions genetically unrelated to each other
Johns Hopkins Researchers Design New Blood Test That Uses DNA ‘Packaging’ Patterns to Detect Multiple Cancer Types
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Findings throw study results into doubt and sheds light on “reproducibility crisis”
Model makes use of genetic and epigenetic factors that combine to initiate disease in mouse 'organoids'
Depression, lack of coping strategies, availability of patient’s “emergency” resources tied to complications.
Mutations in a single human muscle gene tied to rare nasal/sinus cancer
Findings have implications for heart failure, but also for cancer, diabetes and autoimmune disorders
Looking at a certain protein may allow earlier diagnosis of colorectalcancer
New guidelines will give women over 30 years old options about screening for cervical cancer
Researchers diiscovered inhibiting a protein could reduce tumor burdens and enhance the effectiveness of immunotherapy treatments
Researchers at Johns Hopkins received a $3 million grant to better treat liver cancer
Cancer centers across the country endorsed the goal of eliminating cancers caused by HPV with the use of gender-neutral HPV vaccination
Researchers presenting at ASCO 2018 Annual Meeting
BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer impact survival rates
Johns Hopkins-IP Group Collaboration Funds Cancer Therapeutic Startup, Paves Way For Further IP Commercialization
Lorem Therapeutics will use support to enhance drug discovery efforts around critical cancer indications
New ‘Scoring’ System Improves Survival Forecasting Before and After Surgery for Advanced Colorectal Cancer
Advances in efforts to improve the treatment and prognosis of colorectal cancers that have spread to the liver
New 'Scoring' System Improves Survival Forecasting Before and After Surgery for Advanced Colorectal Cancer
A series of papers about a new scoring system that may help improve advanced colorectal cancer prognosis.
Johns Hopkins breast cancer doctor will be honored by the Baltimore Orioles as a Birdland Community Hero.
Five Johns Hopkins Scientists Among 83 Who Will Share in $15 Million Award From Chan Zuckerberg Initiative to Fund Computer-Based Research on Human Cells
The award has been given to scientists who will develop open access tools that visualize, collect and analyze molecular and imaging data.
Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune...
Could help refine biomarkers of cancer risk
In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins...
Johns Hopkins researchers report they have developed two new endoscopic probes that significantly sharpen the technology’s imaging...
Data collected during a long-term health study provides additional evidence for a link between increased risk of cancer in individuals...
Provides unique new framework for early detection of the most common cancers