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Types of Esophageal Cancer We Treat

We understand that a diagnosis of esophageal cancer is life changing. At Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, we are known for our team-driven and patient-centered care for esophageal cancer patients. We treat patients with all types and stages of esophageal cancer, including the most complicated cases. Learn more about our expertise in esophageal cancer treatments.

Types of Esophageal Cancer

Esophageal cancer develops in the esophagus, which is the tube that connects your throat to your stomach. Tumors arise in the mucosa (the inner part of the esophagus), which touches food and water when we swallow.

There are two types of esophageal cancer, each with different risk factors:


Cancers that start in gland cells are called adenocarcinomas. This type of cancer is the most common esophageal cancer. It usually occurs closer to the stomach. Chronic acid reflux, gastroesophageal reflux disease (GERD), Barrett’s esophagus and chronic heartburn can increase your risk of adenocarcinoma esophageal cancer. Read more about Barrett’s esophagus & esophageal cancer.

Squamous Cell Carcinoma

This type of esophageal cancer usually occurs higher up in the esophagus. Squamous cell tumors are associated with heavy alcohol consumption, smoking and organ transplants.

Expert Esophageal Cancer Care at Johns Hopkins

We provide a superior level of expertise in diagnosing and treating both types of esophageal cancer. Wherever you are in the fight against esophageal cancer, we can help.

Learn more about why we’re known as a national leader in esophageal cancer care. Find more information on:

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