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Institutional Review Entity (DURC)
In accordance with this Policy, PIs are to:
- Notify the Institutional Review Entity (IRE) as soon as:
- The PI’s research involves one or more of the agents or toxins listed above;
- The PI’s research with one or more of the agents or toxins listed above also produces, aims to produce, or can be reasonably anticipated to produce one or more of the seven effects listed above or
- The PI’s research that is within the scope of using one or more of the 15 agents/toxins listed above may meet the definition of DURC
The notification must include the PI’s assessment of whether any research involving these agents or toxins produces, aims to produce, or is reasonably anticipated to produce one or more of the effects listed above.
- Work with the IRE to assess the dual use risks and benefits of the DURC and to develop risk mitigation measures.
- Conduct DURC in accordance with the provisions in the risk mitigation plan.
- Be knowledgeable about and comply with all institutional and USG policies and requirements for oversight of DURC.
- Ensure that laboratory personnel (i.e., those under the supervision of laboratory leadership, including graduate students, postdoctoral fellows, research technicians, laboratory staff, and visiting scientists) conducting life sciences research with one or more of the agents listed above have received education and training on DURC.
Communicate DURC in a responsible manner. Communication of research and research findings is an essential activity for all researchers, and occurs throughout the research process, not only at the point of publication. Researchers planning to communicate DURC should do so in compliance with the approved risk mitigation plan.