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Photo of Dr. Murugappan Ramanathan

Murray Ramanathan, Jr, M.D.

Murugappan Ramanathan, Jr, M.D.
Medical Director, Johns Hopkins Otolaryngology-Head and Neck Surgery- National Capital Region
Associate Professor of Otolaryngology - Head and Neck Surgery
Specializes In: Adults (18+ years)

Male  | Languages: English, Tamil

Appointment Phone


Main Location

Johns Hopkins Health Care and Surgery Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Medical Director, Johns Hopkins Otolaryngology-Head and Neck Surgery- National Capital Region
  • Chief, Otolaryngology, Suburban Hospital/Johns Hopkins Medicine
  • Associate Professor of Otolaryngology - Head and Neck Surgery
  • Associate Professor of Neurosurgery

Centers & Institutes



Johns Hopkins Health Care and Surgery Center

Appointment Phone: 301-896-3330

6420 Rockledge Drive
Suite 4920
Bethesda, MD 20817 map


Cerebrospinal Fluid (CSF) Leaks, Chronic Sinusitis with Polyps, Complex Skull Reconstruction, Endoscopic Frontal Sinus Surgery, Esthesioneuroblastoma, Nasal Obstruction, Nasal Polyps, Otolaryngology, Paranasal Sinus Tumors, Pituitary Tumors, Revision Endoscopic Sinus Surgery, Revision Frontal Sinus Surgery, Sellar Tumors, Sinonasal Inverting Papillomas, Sinus Problems, Sinusitis, Sinusitis and Nasal Polyposis, Skull Base Tumors, Suprasellar Tumors

Research Interests

Molecular and immunologic (innate and adaptive) mechanisms underlying the pathogenesis of chronic rhinosinusitis with nasal polyps; Role of Allergy and Environmental pollutants in propagating sinonasal inflammation


Dr. Ramanathan was born and raised in Dallas, TX, and received a bachelor's degree in Molecular Biophysics and Biochemistry from Yale University. He subsequently received his M.D. from The University of Texas Medical Branch at Galveston where he graduated with highest honors and completed his internship in general surgery and residency in otolaryngology-head and neck surgery at Johns Hopkins. Upon completion of his residency, he received additional fellowship training in advanced endoscopic sinus and minimally invasive skull base surgery at Johns Hopkins.

Dr. Ramanathan evaluates patients primarily at the Johns Hopkins Healthcare and Surgery Center in Bethesda, Maryland, as a part of the greater Washington D.C. region practice of Johns Hopkins Otolaryngology-Head and Neck Surgery. If indicated, he can also perform surgery at Suburban Hospital in Bethesda or at Johns Hopkins Hospital in Baltimore.

He maintains a very busy clinical practice primarily focused on complex revision endoscopic sinus surgery, endoscopic approaches to the orbit, and the endoscopic management of sinonasal and skull base tumors including inverted papilloma and esthesioneuroblastoma.  Dr. Ramanathan is also the consultant rhinologist/skull base surgeon for complicated sinusitis and sinonasal/skull base tumor patients at the Warren  Grant Magnuson Clinical Center at the National Institutes of Health in Bethesda 

As a surgeon-scientist, Dr. Ramanathan also directs an National Institutes of Health funded laboratory to study the role of air pollution in causing chronic rhinosinusitis. He is the recipient of numerous prestigious research awards and grants. He has published over 65 peer reviewed articles, reviews, and book chapters and is frequently invited to speak about his research at national and international meetings. more

Featured Video

Meet our Experts - Dr. Murray Ramanathan

More Videos

  • Additional Information

  • Education +


    • University of Texas Medical Branch School of Medicine / MD (2004)


    • Johns Hopkins University School of Medicine / Otolaryngology (2009)


    • American Board of Otolaryngology - Head and Neck Surgery / Otolaryngology (2010)
  • Research & Publications +

    Selected Publications View all on PubMed

    Mendiola M, Tharakan A, Chen M, Asempa T, Lane AP, Ramanathan M Jr. Characterization of a High Dose Ovalbumin Model of Allergic Sinonasal Inflammation. International Forum of Allergy and Rhinology, 2016 Apr 5. doi: 10.1002/alr.21768

    Tharakan A, Halderman A, Lane AP, Biswal S, Ramanathan M Jr.Reversal of Cigarette Smoke Extract Induced Sinonasal Epithelial Cell Barrier Dysfunction Through Nrf2 Activation. International Forum of Allergy and Rhinology, 2016 Aug 31. doi: 10.1002/alr.21827

    London NR, Tharakan A, Rule A, Lane AP, Biswal S, and Ramanathan M Jr. Air pollutant mediated disruption of sinonasal epithelial cell barrier function is reversed by activation of the Nrf2 pathway. Journal of Allergy and Clinical Immunology (2016), doi: 10.1016/j.jaci.2016.06.027

    London NR, Tharakan A, Lane AP, Biswal S, Ramanathan M Jr. Nrf2 activation restores house dust mite induced sinonasal epithelial cell barrier dysfunction, International Forum of Allergy and Rhinology, 2017 May;7(5):536-541. doi: 10.1002/alr.21916

    Ramanathan M Jr., London, NR Jr., Tharakan A, Surya, N., Sussan, TE, Rao, X, Lin, SY, Toskala E, Rajagopalan S, Biswal, S. Airborne particulate matter induces non-allergic eosinophilic sinonasal inflammation in mice. Am J Respir Cell Mol Biol. 2017 Feb 28. doi: 10.1165/rcmb.2016-0351OC

    London NR Jr, Tharakan A, Mendiola M, Sussan TE, Chen M, Dobzanski A, Lane AP, Sidhaye V, Biswal S, Ramanathan M Jr. Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis. Int Forum Allergy Rhinol. 2018 Oct 3. doi: 10.1002/alr.22222. PMID: 30281933

  • Academic Affiliations & Courses +
  • Activities & Honors +


    • Prince Edmund Fowler Award for Outstanding Basic Science Thesis, Triological Society
    • Johns Hopkins Clinician Scientist Award
    • American Rhinologic Society Basic Science Research Award
  • Videos & Media +


    Sinus Surgery Myths | Murray Ramanathan, M.D.”

    Recent News Articles & Media Coverage

    Treatment Options for Sinus Relief Webinar

    Air Pollution May Directly Cause Those Year-Round Runny Noses, According to a Mouse Study Johns Hopkins Press Release April 18, 2017

    Sinonasal Inverted Papilloma Masquerading As Nasal Polyps Johns Hopkins Clinical Connection video

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