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Open Clinical Research Studies

Studies are currently being conducted locally in the following specialty areas, with more specialty studies planned in the future.

Cardiovascular Studies

Contact: 443-546-1400

Study to Evaluate the Efficacy (Effect on Disease) and Safety of Finerenone on Morbidity (Events Indicating Disease Worsening) & Mortality (Death Rate) in Participants With Heart Failure and Left Ventricular Ejection Fraction (Proportion of Blood Expelled Per Heart Stroke) Greater or Equal to 40% (FINEARTS-HF)
Principal Investigator:  Keith Friedman, MD
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A streamlined, multicentre, randomised, parallel group, double-blind placebo-controlled superiority trial to evaluate the effect of EMPAgliflozin on hospitalisation for heart failure and mortality in patients with aCuTe Myocardial Infarction (EMPACT-MI)
Principal Investigator:  Keith Friedman, MD
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A randomized double-blind, placebo-controlled, multicenter trial assessing the impact of lipoprotein (a) lowering with pelacarsen (TQJ230) on major cardiovascular events in patients with established cardiovascular disease- (HORIZON)  
Principal Investigator:  Keith Friedman, MD
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A multicenter, randomized, double-blind, double-dummy, parallel group, active controlled study to evaluate the effect of sacubitril/valsartan (LCZ696) versus valsartan on changes in NT-proBNP and outcomes, safety, and tolerability in HFpEF patients with acute decompensated heart failure (ADHF) who have been stabilized during hospitalization and initiated in-hospital or within 30 days post-discharge (PARAGLIDE-HF)
Principal Investigator:  Keith Friedman, MD
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COOrdinating CaRDIology CliNics Randomized Trial of Interventions to Improve OutcomEs (COORDINATE) - Diabetes
Principal Investigator:  Keith Friedman, MD
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Diabetes

Glycemic Effects of the COVID-19 Booster Vaccine in Type 1 Diabetes
Principal Investigator: Andrew Demidowich, MD
Contact: Mehro Akhtar, (443) 546-1402 or makhtar2@jhmi.edu
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