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Hydroxyurea for the Treatment of Adults with Sickle Cell Disease
The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation Statement
The Johns Hopkins University School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
The Johns Hopkins University has approved this activity for 1.0 contact hours.
American Nurses Credentialing Center
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.
Hydroxyurea is the only FDA approved medication that has been shown to mitigate the effects of sickle cell disease and potentially prolong survival, yet it is underutilized by the patient population. One of the reasons for this lack of utilization of hydroxyurea is the lack of provider knowledge about the disease and the use of hydroxyurea.
This activity is designed to improve provider knowledge about the use of hydroxyurea. This is geared to the providers who are likely to see patients with sickle cell disease, PCP's and hematology/oncology providers.
This activity is intended for primary care providers, hematologists, oncologists and nurses.
After participating in this activity, the participant will demonstrate the ability to:
- Describe the basic pathophysiology of a vaso-occlusive crisis.
- Describe the role of hemoglobin F in sickle cell disease.
- Outline the evidence of hydroxyurea efficacy in sickle cell disease.
- Describe how to use hydroxyurea in adults with sickle cell disease.
The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.
NOTICE ABOUT OFF-LABEL USE PRESENTATIONS
The Johns Hopkins University School of Medicine/Hydroxyurea for the Treatment of Adults with Sickle Cell Disease (EM) may include presentations on drugs or devices, or use of drugs or devices, that have not been approved by the Food and Drug Administration (FDA) or have been approved by the FDA for specific uses only. The FDA has stated that it is the responsibility of the physician to determine the FDA clearance status of each drug or device he or she wishes to use in clinical practice.
The Johns Hopkins University School of Medicine is committed to the free exchange of medical education. Inclusion of any presentation in this program, including presentations on off-label uses, does not imply an endorsement by Johns Hopkins of the uses, products, or techniques presented.
Full Disclosure Policy Affecting CME Activities:
As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) to require signed disclosure of the existence of financial relationships with industry from any individual in a position to control the content of a CME activity sponsored by OCME. Members of the Planning Committee are required to disclose all relationships regardless of their relevance to the content of the activity. Presenters are required to disclose only those relationships that are relevant to their specific presentation. The following relationships have been reported for this activity:
No speaker has indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their
No planner has indicated that they have any financial interests or relationships with a commercial entity.
Note: Grants to investigators at the Johns Hopkins University are negotiated and administered by the institution which receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).
Off-Label Product Discussion
The following speakers have disclosed that their presentation will reference unlabeled/unapproved uses of drugs or products:
No speaker has indicated that they will reference unlabeled/unapproved uses of drugs or products.
The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. This enduring material is produced for educational purposes only. Use of Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.
Internet CME Policy
The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protecting the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based program. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME program. CME collects only the information necessary to provide you with the services that you request.
All rights reserved - The Johns Hopkins University School of Medicine.
CONFIDENTIALITY DISCLAIMER FOR CME CONFERENCE ATTENDEES
I certify that I am attending a Johns Hopkins University School of Medicine CME activity for accredited training and/or educational purposes.
I understand that while I am attending in this capacity, I may be exposed to "protected health information," as that term is defined and used in Hopkins policies and in the federal HIPAA privacy regulations (the "Privacy Regulations"). Protected health information is information about a person’s health or treatment that identifies the person.
I pledge and agree to use and disclose any of this protected health information only for the training and/or educational purposes of my visit and to keep the information confidential.
I agree not to post or discuss this protected health information, including pictures and/or videos, on any social media site (e.g. Facebook, Twitter, etc.), in any electronic messaging program or through any portable electronic device.
I understand that I may direct to the Johns Hopkins Privacy Officer any questions I have about my obligations under this Confidentiality Pledge or under any of the Hopkins policies and procedures and applicable laws and regulations related to confidentiality. The contact information is: Johns Hopkins Privacy Officer, telephone: 410-735-6509, e-mail: HIPPA@jhmi.edu
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Johns Hopkins University School of Medicine
Office of Continuing Medical Education
Turner 20/720 Rutland Avenue
Baltimore, Maryland 21205-2195
Reviewed & Approved by:
General Counsel, Johns Hopkins Medicine (4/1/03)
Method of Participation
Participants will follow the link below to complete the pre‐test. Upon completion of the pre‐test, participants will be directed to the video content, totaling 1 hour in length. After viewing the content the participant will then click the link in the content description which will direct them to the Johns Hopkins Office of Continuing Medical Education Website to complete the post-test and evaluation.
In order to receive credit, participants must visit the Johns Hopkins Office of Continuing Medical Education website to register, complete a post‐test and activity evaluation and upon receiving a score of 70% or above will be able to print a certificate.
Date of Release and Expiration
Release Date: 12/1/2014
Expiration Date: 12/1/2016
Post-test and evaluation must be submitted by the expiration date in order to be eligible for credit.
Estimated Time to Complete This Educational Activity
This activity will take no longer that 60 minutes to complete.
Course Director and Speaker
Sophie Lanzkron MD, MHS
Associate Professor of Medicine and Oncology
There are no prerequisites to participate in this activity.
For questions or technical issues, please contact the Sickle Cell Office:
Yetunde Olagbaju, MHA
Research Program Coordinator
To participate in additional CME activities presented by the Johns Hopkins University School of Medicine Continuing Medical Education Office, please visit https://hopkinscme.cloud-cme.com