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Clinical and Translational Research Programs

Last updated: July 2016

Outcomes/Clinical Research

  1. Induction therapy for esophageal cancer
  2. Induction therapy for mesothelioma
  3. Adjuvant chemo for lung cancer
  4. CT screening for second primaries
  5. PET/CT pre and post induction
  6. Outcomes in pectus in the adult
  7. Incidence of cancer in high grade Barrett’s dysplasia is there a change
  8. Geriatrics:  induction therapy, lung cancer, esophageal cancer, QOL
  9. Complicated esophageal reconstructions
  10. Outcomes from bilateral sequential thoracotomies
  11. Robotics in thoracic surgery
  12. Esophageal cancer in the African-American
  13. Socioeconomic status and lung cancer
  14. Lung cancer in patients under 40
  15. Tobacco and multiple cancers
  16. Characterization of non-smoking lung cancer patients
  17. Second lung primaries and survival

Translational Research

  1. Methylation in old vs. young cancer patients
  2. Methylation in specific anatomical areas
  3. Profiling metastasis vs. primary tumors in lung cancer
  4. Methylation Profiles of Patients with Recurrent Lung Cancer
  5. New Methods of Detecting DNA Methylation using Nanotechnology

Case Studies

  1. RFA/esophageal injury
  2. CAM with systemic arterial supply
  3. Unusual tumors of the lung
  4. Results of 3 Patient Response to Epigenetic Therapy

NCI Funded Clinical Research

  1. Screening for cancer in the HIV patient
  2. Hypermethylation in lung cancer and lymph nodes
  3. Hypermethylation as a predictor of chemosensitivity in esophageal cancer
  4. Adjuvant Epigenetic Therapy in Early Non-Small Lung Cancer
  5. Molecular Profiling of Lung Cancers from HIV positive patients
  6. Epigenetic Therapy in Rodents with Lung Cancer
  7. The NCI Cancer Genome Atlas Project Profiling of Squamous Carcinomas of the Lung

National Trials

  1. Resectable small cell ca (proposed ACOSOG)
  2. Geriatrics database (proposed ACOSOG/ECOG)
  3. ACOSOG Sublobar resection with brachytherapy
  4. ACOSOG  RFA for lung tumors
  5. Adjuvant Epigenetic Therapy in Early Non-Small Lung Cancer (SPORE/Stand Up 2 Cancer)
  6. Validation of Epigenetic Biomarkers of Lung Cancer Recurrence (ACOSOG Correlative Study to Z0040, CALGB)
  7. Testing Epigenetic Biomarkers of Chemosensitivity in Esophageal Cancer (ACOSOG Correlative Study to Z4051

International Trials

  1. Validation of Epigenetic Biomarkers of Lung Cancer Recurrence in Israel (FAMRI Israel-New York-Hopkins Collaborative)
  2. Validation of Epigenetic Biomarkers of Esophageal Cancer Recurrence in Japan