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Ciccarone Articles

Ciccarone Center Research

Topic

Diabetes & Metabolic Syndrome

Landmark Articles

The role of statins in diabetes treatment.
By: Subedi BH, Tota-Maharaj R, Silverman MG, Minder CM, Martin SS, Ashen MD, Blumenthal RS, Blaha MJ.
Diabetes is considered a risk equivalent for coronary heart disease (CHD). The use of statins for primary and secondary prevention in patients with diabetes is well established and supported by robust data from randomized, controlled trials and national guidelines. It is reasonable to match the intensity of statin therapy with patients’ baseline CVD risk.
Mild cognitive dysfunction does not affect diabetes control in minority elders.
By: Palta P, Golden SH, Teresi JA, Palmas W, Trief P, Weinstock RS, Shea A, Manly JJ, Luchsinger JA.
Mild cognitive impairment was not associated with metabolic control of diabetes among minority elderly individuals.
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Significant depressive symptoms are not associated with diabetes control in minority elderly.
By: Palta P, Golden SH, Teresi JA, Palmas W, Trief P, Weinstock RS, Shea A, Manly JJ, Luchsinger JA.
Elevated depressive symptoms were not associated with metabolic control of diabetes among minority elderly individuals.
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Early readmission among patients with diabetes: A qualitative assessment of contributing factors.
By: Rubin DJ, Donnell-Jackson K, Jhingan R, Golden SH, Paranjape A.
Findings from this qualitative study suggest several interventions that may reduce the risk of early readmission for patients with diabetes, including inpatient diabetes education, improving communication of discharge instructions, and involving patients more in medication reconciliation and post-discharge planning.
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A clinician’s guide to the updated ABCs of cardiovascular disease prevention.
By: Kohli P, Whelton SP, Hsu S, Yancy CW, Stone NJ, Chrispin J, Gilotra NA, Houston B, Ashen MD, Martin SS, Joshi PH, McEvoy JW, Gluckman TJ, Michos ED, Blaha MJ, Blumenthal RS.

To facilitate the guideline-based implementation of treatment recommendations in the ambulatory setting and to encourage participation in the multiple preventive health efforts that exist, we have organized several recent guideline updates into a simple ABCDEF approach. We would remind clinicians that evidence-based medicine is meant to inform recommendations but that synthesis of patient-specific data and use of appropriate clinical judgment in each individual situation is ultimately preferred.

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NIDDK international conference report on diabetes and depression: Current understanding and future directions.
By: Holt RIG, deGroot M, Lucki I, Hunter CM, Sartorius N, Golden SH.
Comorbid diabetes and depression are a major clinical challenge as the outcomes of each condition are worsened by the other. This article summarizes the presentations and discussions during an international meeting on diabetes and depression convened by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in collaboration with the National Institute of Mental Health and the Dialogue on Diabetes and Depression.
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Understanding the high prevalence of diabetes in U.S. South Asians compared with four racial/ethnic groups: The MASALA and MESA Studies.
By: Kanaya AM, Herrington D, Vittinghoff E, Ewing SK, Liu K, Blaha MJ, Dave SS, Qureshi F, Kandula NR.
This study compared South Asians with four other racial/ethnic groups in the U.S. to determine whether socio-demographic, lifestyle, or metabolic factors could explain the higher diabetes prevalence and whether insulin resistance and beta-cell dysfunction occurred at younger ages and/or lower adiposity levels compared with other groups.
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Does hormone therapy affect blood pressure changes in the Diabetes Prevention Program?
By: Kim C, Golden SH, Kong S, Nan B, Mather KJ, Barrett-Connor, Diabetes Prevention Program Research Group.

Among overweight women with dysglycemia, the magnitude of blood pressure reductions after intensive lifestyle change is unrelated to postmenopausal estrogen use.

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Diabetes and depression.
By: Holt RI, de Groot M, Golden SH.
Both psychological interventions and antidepressants are effective in treating depressive symptoms in people with diabetes but have mixed effects on glycemic control.
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Does hormone therapy affect blood pressure in the Diabetes Prevention Program?
By: Kim C, Golden SH, Kong S, Nan B, Mather K, Barrett-Connor E; for the Diabetes Prevention Program Research Group.

This study aims to examine whether blood pressure reductions differ by estrogen use among overweight glucose-intolerant women. Among overweight women with dysglycemia, the magnitude of blood pressure reductions after ILS is unrelated to postmenopausal estrogen use.

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