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Ciccarone Center Research
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- Meet the Authors
Diabetes & Metabolic Syndrome
To facilitate the guideline-based implementation of treatment recommendations in the ambulatory setting and to encourage participation in the multiple preventive health efforts that exist, we have organized several recent guideline updates into a simple ABCDEF approach. We would remind clinicians that evidence-based medicine is meant to inform recommendations but that synthesis of patient-specific data and use of appropriate clinical judgment in each individual situation is ultimately preferred.Published in: Journal of the American Heart AssociationRead on Pubmed
Potential implications of coronary artery calcium testing for guiding aspirin use among asymptomatic individuals with diabetes.
We conclude that CAC can help risk stratify individuals with diabetes and may aid in selection of patients who may benefit from therapies such as low-dose aspirin for primary prevention of CVD.Published in: Diabetes CareRead on Pubmed
Hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased systemic inflammation.
The goal of this study was to assess the independent and collective associations of hepatic steatosis, obesity, and the metabolic syndrome with elevated hsCRP levels. We evaluated 2,388 individuals without clinical cardiovascular disease between December 2004 and December 2006. Hepatic steatosis was diagnosed by ultrasound, and the metabolic syndrome was defined using National Heart, Lung, and Blood Institute criteria. We concluded that hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased odds of high hsCRP levels.Published in: Arteriosclerosis, Thrombosis & Vascular BiologyRead on Pubmed
Insulin requirements in non-critically ill hospitalized diabetic patients with steroid-induced hyperglycemia.
Noncritically ill patients with hyperglycemia receiving steroids require a higher percentage of TDD insulin therapy as nutritional insulin to achieve normoglycemia.
Type 2 diabetes and cardiovascular disease: what next?
CVD in Type 2 diabetes is multifactorial and requires a multifaceted approach in reducing known cardiovascular risks, at both the individual patient and societal levels.
Insulin requirements in non-critically ill hospitalized patients with diabetes and steroid-induced hyperglycemia.
Noncritically ill patients with hyperglycemia receiving steroids require a higher percentage of total daily dose insulin therapy as nutritional insulin to achieve normoglycemia.
Impact of a pharmacy-based glucose management program on glycemic control in an inpatient general medicine population.
This study found no global benefit of the pharmacy-based glucose management program for improving blood glucose values compared with usual care.
Race/ethnic difference in diabetes and diabetic complications.
This study's data provide novel updates on race/ethnic differences in children and adults with type 1 diabetes, children with type 2 diabetes, and in Latino subpopulations.
High-priority research needs for insulin delivery and glucose monitoring methods.
This article summarizes future research needs in the area of technologies for insulin delivery and glucose monitoring methods.Read on Pubmed
A systematic review: burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; should we care?
Considerable evidence supports the association of nonalcoholic fatty liver disease with subclinical atherosclerosis, independent of traditional risk factors and metabolic syndrome.
Validity of meta-analysis in diabetes: meta-analysis is an indispensable tool in evidence synthesis.
This article presents supporting arguments to support the use for meta-analysis in diabetes clinical research in a pro-con debate.