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Ciccarone Articles

Ciccarone Center Research


Quality of Care

Landmark Articles

Methods for estimation of disparities in medication use in an observational cohort study: results from the Multi-Ethnic Study of Atherosclerosis.
By: McClelland RL, Jorgensen NW, Post WS, Szklo M, Kronmal RA.
Evaluating disparities in health care is an important aspect of understanding differences in disease risk. The purpose of this study is to describe the methodology for estimating such disparities, to provide improved disparity estimation in a large multi-ethnic cohort study.
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Comparing the new European cardiovascular disease prevention guideline with prior American Heart Association guidelines: an editorial review.
By: Ton VK, Martin SS, Blumenthal RS, Blaha MJ.
Despite some minor disagreements on the weight of recommendations in certain areas, CVD prevention experts across two continents agree on one thing: prevention works in halting the progression of atherosclerosis and decreasing disease burden over a lifetime.
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Establishing a successful coronary CT angiography program in the emergency department: Official writing of the Fellow and Resident Leaders of the Society of Cardiovascular Computed Tomography (FiRST).
By: Maroules CD, Blaha MJ, El-Haddad MA, Ferencik M, Cury RC.
Recent multicenter trials have reported that coronary CT angiography is safe, reduces time to diagnosis, facilitates discharge, and may lower overall cost compared with routine care. This study provides a 10-step approach for establishing a successful coronary CT angiography program in the emergency department.
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Patient- and trial-specific barriers to participation in cardiovascular randomized clinical trials.
By: Martin SS, Ou FS, Newby LK, Sutton V, Adams P, Felker GM, Wang TY.
This study quantitatively examined the association of patient- and trial-specific factors with participation in cardiovascular randomized clinical trials.
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Modifiable factors associated with failure to attain low-density lipoprotein cholesterol goal at 6 months after acute myocardial infarction.
By: Martin SS, Gosch K, Kulkarni KR, Spertus JA, Mathews R, Ho PM, Maddox TM, Newby LK, Alexander KP, Wang TY.
Findings from this study support targeted interventions in the transition of acute myocardial infarction care to promote affordable statin prescription at discharge, medication persistence and adherence, and cardiac rehabilitation participation.
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What is the role of calcium scoring in the age of coronary computed tomographic angiography?
By: Joshi PH, Blaha MJ, Blumenthal RS, Blankstein R, Nasir K.

Available data suggest that in low-to-intermediate risk symptomatic patients, CAC scanning may serve as an appropriate gatekeeper to further testing with either coronary computed tomographic angiography, functional imaging, or invasive coronary angiography.

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Utility of coronary artery calcium scoring in the evaluation of patients with chest pain.
By: Tota-Maharaj R, McEvoy JW, Blaha MJ, Silverman MG, Nasir K, Blumenthal RS.
Although further research is needed, carefully selected patients presenting to the emergency department with a normal electrocardiogram, normal cardiac biomarkers, and no CAC may be considered for early discharge without further testing.
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Comparative effectiveness and safety of methods of insulin delivery and glucose monitoring for diabetes mellitus: A systematic review and meta-analysis.
By: Yeh HC, Brown TT, Maruthur N, Ranasinghe P, Berger Z, Suh YD, Wilson LM, Haberl EB, Brick J, Bass EB, Golden SH.
Continuous subcutaneous insulin infusion and multiple daily injections have similar effects on glycemic control and hypoglycemia, except continuous subcutaneous insulin infusion has a favorable effect on glycemic control in adults with type 1 diabetes mellitus. For glycemic control, real-time continuous glucose monitoring is superior to self-monitoring of blood glucose, and sensor-augmented insulin pumps are superior to multiple daily injections and self-monitoring of blood glucose without increasing the risk for hypoglycemia.
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Health disparities in endocrine disorders: Biological, clinical, and nonclinical factors — an Endocrine Society Scientific Statement.
By: Golden SH, Brown A, Cauley JA, Chin MH, Gary-Webb TL, Kim C, Sosa JA, Sumner AE, Anton B.
There is little evidence that genetic differences contribute significantly to race/ethnic disparities in the endocrine disorders examined. Multilevel interventions have reduced disparities in diabetes care, and these successes can be modeled to design similar interventions for other endocrine diseases.
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A national interactive Web-based physical activity intervention in women, evaluation of the American Heart Association Choose to Move program 2006-2007.
By: Lieber SB, Redberg RF, Blumenthal RS, Gandhi A, Robb KJ, Mora S.
In this national cohort of women, a 12-week Web-based intervention improved physical activity and quality of life measurements, resulting in higher short-term physical activity guideline compliance and better quality of life. Increasing use of this simple Web-based tool could improve physical activity and promote disease prevention.
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