Response to letter by Dr. Lin regarding article, “HDL cholesterol subclasses, myocardial infarction, and mortality in secondary prevention: the lipoprotein investigators collaborative.
By: Martin SS, Li Y, Spertus JA, Jones SR.
Low zinc levels is associated with increased inflammatory activity but not with atherosclerosis, arteriosclerosis or endothelial dysfunction among the very elderly.
By: De Paula R, Aneni EC, Costa AR, Figueiredo VN, Moura FA, Freitas WM, Quaglia LA, Santos SN, Soares AA, Nadruz W, Blaha MJ, Blumenthal RS, Agatston A, Nasir K, Sposito AC.
Reduced zinc intake has been related to atherogenesis and arteriosclerosis. We verified this assumption in very old individuals, who are particularly prone to both zinc deficiency and structural and functional changes in the arterial wall. Although plasma zinc level is inversely related to systemic inflammatory activity, its plasma levels of daily intake are not associated to alterations in structure or function of the arterial wall. In the very elderly, plasma concentrations or daily intake of zinc is not related to endothelial dysfunction, arteriosclerosis, or atherosclerotic burden at coronary or carotid arteries.
A community-engaged cardiovascular health disparities research training curriculum: Implementation and preliminary outcomes.
By: Golden SH, Purnell T, Halbert J, Matens R, Miller ER, Levine D, Nguyen TH, Gudzune KA, Crews DC, Mahlangu-Ngcobo M, Cooper LA.
This manuscript summarizes the key elements, implementation, and preliminary outcomes of the CVD Disparities Fellowship and Summer Internship Programs at the Johns Hopkins University Schools of Medicine, Nursing, and Bloomberg School of Public Health.
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A clinician’s guide to the updated ABCs of cardiovascular disease prevention.
By: Kohli P, Whelton SP, Hsu S, Yancy CW, Stone NJ, Chrispin J, Gilotra NA, Houston B, Ashen MD, Martin SS, Joshi PH, McEvoy JW, Gluckman TJ, Michos ED, Blaha MJ, Blumenthal RS.
To facilitate the guideline-based implementation of treatment recommendations in the ambulatory setting and to encourage participation in the multiple preventive health efforts that exist, we have organized several recent guideline updates into a simple ABCDEF approach. We would remind clinicians that evidence-based medicine is meant to inform recommendations but that synthesis of patient-specific data and use of appropriate clinical judgment in each individual situation is ultimately preferred.
- Journal:
Journal of the American Heart Association
- Year: 2014
- Topics:
Antiplatelet Therapy,
ASCVD (Atherosclerotic Cardiovascular Disease),
Blood Pressure,
Cholesterol / Lipids / Statins,
Cigarette Smoking,
Diabetes & Metabolic Syndrome,
Diet & Weight,
Exercise and Physical Fitness,
Quality of Care
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Erin Michos, MD, MHS,
Marie (Dominique) Ashen, CRNP, PhD,
Seth Martin, MD, MHS,
J. Bill McEvoy, MB BCh, MHS
Read on Pubmed
Improving lipid control following myocardial infarction.
By: Ankam J, Feldman DI, Blaha MJ, Martin SS.
Following a myocardial infarction, lipid-lowering therapy is an established intervention to reduce the risk of recurrent cardiovascular events. Prior studies show a need to improve clinical practice in this area. Here, we review the latest research and perspectives on improving postmyocardial infarction lipid control. Optimizing lipid control could further enhance clinical outcomes after myocardial infarction.
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Comparison of racial differences in plaque composition and stenosis between HIV-positive and HIV-negative men from the Multicenter AIDS Cohort Study.
By: Miller PE, Budoff M, Zikusoka M, Li X, Palella F Jr, Kingsley LA, Witt MD, Sharrett AR, Jacobson LP, Post WS.
The lower prevalence of CAC in black men compared with white men appears to reflect less calcification of plaque and stenosis rather than a lower overall prevalence of plaque.
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Non-cardiovascular effects associated with statins.
By: Desai CS, Martin SS, Blumenthal RS.
This is a state-of-art review on the possible effects of statin therapy on organs not in the cardiovascular system.
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Vitamin D and subclinical cerebrovascular disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study.
By: Michos ED, Carson KA, Schneider AL, Lutsey PL, Xing L, Sharrett AR, Alonso A, Coker LH, Gross M, Post W, Mosley TH, Gottesman RF.
single measure of 25-hydroxy vitamin D was not cross-sectionally associated with white matter hyper-intensities grade or prevalent subclinical infarcts and was not prospectively associated with their progression or subclinical brain infarcts seen on serial cerebral MRIs obtained approximately 10 years apart.
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2013 American cholesterol treatment guideline: what was done well and what could be done better.
By: Martin SS, Abd TT, Jones SR, Michos ED, Blumenthal RS, Blaha MJ.
This article critically appraises the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol. The guideline succeeds in prioritizing statin therapy, expanding focus to atherosclerotic cardiovascular disease including stroke, and in emphasizing absolute cardiovascular risk to determine statin eligibility.
- Journal:
Journal of the American College of Cardiology
- Year: 2014
- Topics:
ASCVD (Atherosclerotic Cardiovascular Disease),
Cholesterol / Lipids / Statins,
Cardiovascular Risk Assessment
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Erin Michos, MD, MHS,
Seth Martin, MD, MHS,
Steven Jones, MD
Read on Pubmed
Letter by Jones et al regarding article, “Elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation.”
By: Jones SR, Martin SS, Brinton EA.
Read on Pubmed
