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Ciccarone Articles

Ciccarone Center Research


International Journal of Cardiology

Myocardial steatosis and its association with obesity and regional ventricular dysfunction: evaluated by magnetic resonance tagging and 1H spectroscopy in healthy African Americans.
By: Liu CY, Bluemke DA, Gerstenblith G, Zimmerman SL, Li J, Zhu H, Lai S, Lai H.
This study found no relationship between cardiac steatosis and left ventricular volumes or ejection fraction, though there is some evidence suggesting that cardiac steatosis may be associated with LV regional function in healthy African-American women.
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Modifiable lifestyle risks, cardiovascular disease, and all-cause mortality.
By: Ahmed HM, Blaha MJ, Blumenthal RS.
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Differences in coronary plaque composition with aging measured by coronary computed tomography angiography.
By: Tota-Maharaj R, Blaha MJ, Rivera JJ, Henry TS, Choi EK, Chang SA, Yoon YE, Chun EJ, Choi SI, Blumenthal RS, Chang HJ, Nasir K.
Little is known about the independent impact of aging on coronary plaque morphology and composition in the era of CCTA. We studied 1,015 consecutive asymptomatic South Korean subjects (49±10years, 64% men) who underwent 64-slice CCTA during routine health evaluation. Coronary plaque characteristics were analyzed on a per-segment basis according to the modified AHA classification. In conclusion, CCTA is an effective method for measuring age-related differences in the burden of individual coronary plaque subtypes. Future research is needed to determine whether the increase in mixed and calcified plaques seen with aging produce an independent contribution to the age-related increase in cardiovascular risk.
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