Hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased systemic inflammation.
The goal of this study was to assess the independent and collective associations of hepatic steatosis, obesity, and the metabolic syndrome with elevated hsCRP levels. We evaluated 2,388 individuals without clinical cardiovascular disease between December 2004 and December 2006. Hepatic steatosis was diagnosed by ultrasound, and the metabolic syndrome was defined using National Heart, Lung, and Blood Institute criteria. We concluded that hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased odds of high hsCRP levels.
- Journal: Arteriosclerosis, Thrombosis & Vascular Biology
- Year: 2011
- Topic: Cardiac CT, Diabetes & Metabolic Syndrome, Diet & Weight, Inflammation
- Read more articles by: Roger S. Blumenthal, MD, Chiadi Ndumele, MD, MHS, Khurram Nasir, MD, MPH
