Comparison of racial differences in plaque composition and stenosis between HIV-positive and HIV-negative men from the Multicenter AIDS Cohort Study.
The lower prevalence of CAC in black men compared with white men appears to reflect less calcification of plaque and stenosis rather than a lower overall prevalence of plaque.
Vitamin D and subclinical cerebrovascular disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study.
single measure of 25-hydroxy vitamin D was not cross-sectionally associated with white matter hyper-intensities grade or prevalent subclinical infarcts and was not prospectively associated with their progression or subclinical brain infarcts seen on serial cerebral MRIs obtained approximately 10 years apart.
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
This integration of common variant association, expression and orthogonal protein-protein interaction screens provides new insights into cardiac electrophysiology and identifies new candidate genes for ventricular arrhythmias, long-QT syndrome, and sudden cardiac death.
Associations of common carotid intima-media thickness with coronary heart disease risk factors and events vary with distance from the carotid bulb.
Common carotid artery intima-media thickness (IMT) measurements made below the carotid bulb are smaller but have more consistent associations with CHD risk factors and outcomes compared with IMT measured near the bulb.
Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study.
This study of late middle age white and black participants did not find significant associations between lower levels of 25-hydroxy vitamin D with lower cognitive test scores at baseline, change in scores over time or dementia risk.
Risk factors for fatty liver in the Multicenter AIDS Cohort Study.
Though treated HIV infection was associated with a lower prevalence of fatty liver, prolonged exposure to dideoxynucleoside analogs is associated with higher prevalence.
Epicardial fat is associated with duration of antiretroviral therapy and coronary atherosclerosis.
Greater epicardial fat volume in HIV-infected men and its association with coronary plaque and antiretroviral therapy duration suggest potential mechanisms that might lead to increased risk for cardiovascular disease in HIV.
Incident stroke is associated with common carotid artery diameter and not common carotid artery intima-media thickness.
Though common carotid IMT is not associated with stroke, inter-adventitial diameter of the common carotid artery is independently associated with first-time incident ischemic stroke even after adjusting for IMT.