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Roger S. Blumenthal, MD

Ciccarone Center Research

Published By

Roger S. Blumenthal, MD

Roger S. Blumenthal, MD
Blumenthal, Roger S., MD

Roger S. Blumenthal, MD is Director of the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease and a Professor of Medicine.

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Landmark Articles

Risk and the physics of clinical prediction.

By: McEvoy JW, Diamond GA, Detrano RC, Kaul S, Blaha MJ, Blumenthal RS, Jones SR.
This study shifts the focus from prediction of events to detection of disease in the effort to improve personalized decision-making and outcomes. It also discusses innovative future strategies for risk estimation and treatment allocation in preventive cardiology.

2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk.

By: Abd TT, Misra S, Ojeifo O, Martin SS, Blumenthal RS, Foody J, Wong ND.
The 2013 lifestyle guidelines provide guidance in three narrowly focused areas: 1) the effect of dietary patterns and macronutrient composition on CVD risk factors; 2) the effect of sodium and potassium on CVD risk factors; and 3) the effect of physical activity on blood pressure and lipids.

Delayed heart rate recovery is strongly associated with early and late-stage prehypertension during exercise stress testing.

By: Aneni E, Roberson LL, Shaharyar S, Blaha MJ, Agatston AA, Blumenthal RS, Meneghelo RS, Conceiçao RD, Nasir K, Santos RD.
Among asymptomatic patients undergoing stress testing, delayed heart rate recovery was independently associated with early and late stages of prehypertension.

Focused update on the 2013-2014 cardiovascular disease prevention guidelines.

Risk factors: new risk-assessment guidelines— more or less personalized?

By: Blaha MJ, Blumenthal RS.
The new ACC/AHA cardiovascular-risk guidelines feature updated equations for women, distinct equations for African-Americans, and include stroke prediction. However, the equations rely on the same traditional risk factors as previous versions, are driven predominantly by age, and curtail the intermediate-risk group, in which personalized risk assessment is recommended.

Critical review of high-sensitivity C-reactive protein and coronary artery calcium for the guidance of statin allocation: head-to-head comparison of the JUPITER and St. Francis Heart Trials.

By: Kim J, McEvoy JW, Nasir K, Budoff MJ, Arad Y, Blumenthal RS, Blaha MJ.
This analysis looks at the strengths and limitations of two large trials of statin therapy based on persons with an elevated hsCRP, CAC score, or both.

Concepts and controversies: the 2013 American College of Cardiology/American Heart Association risk assessment and cholesterol treatment guidelines.

By: Martin SS, Blumenthal RS.
This editorial discusses the strengths and limitations of the new prevention guidelines.

Modifiable lifestyle risks, cardiovascular disease, and all-cause mortality.

C-reactive protein is independently associated with coronary atherosclerosis burden among octogenarians.

By: Quaglia LA, Freitas WM, Soares AA, Santos RD, Nadruz W, Blaha MJ, Coelho OR, Blumenthal R, Agatston A, Nasir K, Sposito AC.
We examined measures of inflammation and subclinical atherosclerosis in persons with successful cardiovascular aging.

Family history of coronary heart disease and the incidence and progression of coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA).

By: Pandey AK, Blaha MJ, Sharma K, Rivera J, Budoff MJ, Blankstein R, Al-Mallah M, Wong ND, Shaw L, Carr J, O’Leary D, Lima JA, Szklo M, Blumenthal RS, Nasir K.

A multiethnic, population-based study showed that a family history of premature CHD is associated with enhanced development and progression of subclinical disease, independent of other risk factors.