Role of troponin in patients with chronic kidney disease and suspected acute coronary syndromes: a systematic review.
By: Stacy SR, Suarez-Cuervo C, Berger Z, Wilson LM, Yeh HC, Bass EB, Michos ED.
In chronic kidney disease patients suspected of having acute coronary syndromes, troponin levels can aid in identifying patients with a poor prognosis, but the diagnostic utility is limited by varying estimates of sensitivity and specificity.
Prognostic value of cardiac troponins in chronic kidney disease patients without a suspected acute coronary syndrome: a systematic review.
By: Michos ED, Wilson LM, Yeh HC, Berger Z, Suarez-Cuervo C, Stacy SR, Bass EB.
In chronic kidney disease patients without suspected acute coronary syndromes, troponin elevations were associated with worse prognosis.
A clinician’s guide to the updated ABCs of cardiovascular disease prevention.
By: Kohli P, Whelton SP, Hsu S, Yancy CW, Stone NJ, Chrispin J, Gilotra NA, Houston B, Ashen MD, Martin SS, Joshi PH, McEvoy JW, Gluckman TJ, Michos ED, Blaha MJ, Blumenthal RS.
To facilitate the guideline-based implementation of treatment recommendations in the ambulatory setting and to encourage participation in the multiple preventive health efforts that exist, we have organized several recent guideline updates into a simple ABCDEF approach. We would remind clinicians that evidence-based medicine is meant to inform recommendations but that synthesis of patient-specific data and use of appropriate clinical judgment in each individual situation is ultimately preferred.
- Journal:
Journal of the American Heart Association
- Year: 2014
- Topic:
Antiplatelet Therapy,
ASCVD (Atherosclerotic Cardiovascular Disease),
Blood Pressure,
Cholesterol / Lipids / Statins,
Cigarette Smoking,
Diabetes & Metabolic Syndrome,
Diet & Weight,
Exercise and Physical Fitness,
Quality of Care
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Erin Michos, MD, MHS,
Marie (Dominique) Ashen, CRNP, PhD,
Seth Martin, MD, MHS,
J. Bill McEvoy, MB BCh, MHS
Read on Pubmed
Serum magnesium, phosphorus, and calcium are associated with risk of incident heart failure: the Atherosclerosis Risk in Communities (ARIC) Study.
By: Lutsey PL, Alonso A, Michos ED, Loehr LR, Astor BC, Coresh J, Folsom AR.
Low serum magnesium and high serum phosphorus and calcium were independently associated with greater risk of incident HF in this population-based cohort.
Vitamin D and subclinical cerebrovascular disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study.
By: Michos ED, Carson KA, Schneider AL, Lutsey PL, Xing L, Sharrett AR, Alonso A, Coker LH, Gross M, Post W, Mosley TH, Gottesman RF.
single measure of 25-hydroxy vitamin D was not cross-sectionally associated with white matter hyper-intensities grade or prevalent subclinical infarcts and was not prospectively associated with their progression or subclinical brain infarcts seen on serial cerebral MRIs obtained approximately 10 years apart.
Headed in the right direction but at risk for miscalculation: a critical appraisal of the 2013 ACC/AHA risk assessment guideline.
By: Amin NP, Martin SS, Blaha MJ, Nasir K, Blumenthal RS, Michos ED.
The newly released 2013 ACC/AHA Guideline for Assessing Cardiovascular Risk was a major advance over prior guidelines, but the new risk equations do not appear to lead to significantly better discrimination than older models. Since the same risk factors are incorporated, using the new risk estimators may lead to inaccurate assessment of atherosclerotic cardiovascular risk in certain groups of patients. There also is likely an overestimation of risk when applied to modern populations. Future guidelines could provide clearer direction on which individuals would benefit from additional testing for more personalized preventive therapies.
- Journal:
Journal of the American College of Cardiology
- Year: 2014
- Topic:
Cholesterol / Lipids / Statins,
Cardiovascular Risk Assessment
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Erin Michos, MD, MHS,
Khurram Nasir, MD, MPH,
Seth Martin, MD, MHS
Read on Pubmed
2013 American cholesterol treatment guideline: what was done well and what could be done better.
By: Martin SS, Abd TT, Jones SR, Michos ED, Blumenthal RS, Blaha MJ.
This article critically appraises the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol. The guideline succeeds in prioritizing statin therapy, expanding focus to atherosclerotic cardiovascular disease including stroke, and in emphasizing absolute cardiovascular risk to determine statin eligibility.
- Journal:
Journal of the American College of Cardiology
- Year: 2014
- Topic:
ASCVD (Atherosclerotic Cardiovascular Disease),
Cholesterol / Lipids / Statins,
Cardiovascular Risk Assessment
- Read more articles by:
Roger S. Blumenthal, MD,
Michael Blaha, MD, MPH,
Erin Michos, MD, MHS,
Seth Martin, MD, MHS,
Steven Jones, MD
Read on Pubmed
Fibroblast growth factor-23 and incident coronary heart disease, heart failure, and cardiovascular mortality: the atherosclerosis risk in communities study.
By: Lutsey PL, Alonso A, Selvin E, Pankow JS, Michos ED, Agarwal SK, Loehr LR, Eckfeldt JH, Coresh J.
High levels of serum FGF-23 were associated with increased risk of coronary heart disease, heart failure, and cardiovascular mortality in this large, biracial, population-based cohort.
Invited commentary: the association of low vitamin D with cardiovascular disease — getting at the “heart and soul” of the relationship.
By: Schneider AL, Michos ED.
The authors place the results from the Heart and Soul study in context with the existing literature and propose future directions for vitamin D research.
