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Gynecology & Obstetrics

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Endometriosis Research at Johns Hopkins

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Endometriosis research is a focal point of Johns Hopkins gynecologic research. We strive to understand not only the causes and development of endometriosis but also work to find better methods of diagnosing and treating the condition.

Our team collaborates with the Howard W. and Georgeanna Seegar Jones Laboratory of Reproductive Sciences and Women's Health Research and the Richard W. TeLinde Gynecologic Laboratory to study the molecular pathogenesis and translational aspects of endometriosis. We also work with the National Institutes of Health (NIH) to investigate the development of endometriosis. Our focus is to assess new biomarkers that aid in risk prediction and develop less invasive methods for early detection and diagnosis.

Additionally, our team has applied next-generation sequencing and other state-of-the-art technologies to explore the origin, clonal evolution and mechanisms of the “metastatic” nature of endometriosis. We study cases with these mutations without cancer and those that develop into endometriosis-related ovarian cancers.