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Ya-Yuan Fu

Postdoctoral Fellow


Phone number:  410-955-8608

Research interests:  Enteric nervous system
Clinical interests:  Enteric nervous system-physiology and regeneration, remodeling of enteric neurovascular complex in inflammatory condition  

Schools\degrees:  Ph.D., Chemical Engineering, National Tsing Hua University, Taiwan
Training: Postdoctoral fellow, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine

Research summary

Dr. Fu’s research objectives focus on the use of three-dimensional imaging techniques to generate 3-D microstructure, vasculature and innervation of intestinal and pancreatic tissues under normal and diseased conditions. The 3-D imaging technique is also used to study the enteric neural stem cells in situ.

Journal citations

  1. Fu YY and Tang SC.  At the movies: 3-dimensional technology and gastrointestinal histology. Gastroenterology, 139(4): p1100-1105, 2010. PMID 20728448
  2. Fu YY, Lin CW, Enikolopov G, Sibley E, Chiang AS, and Tang SC. Microtome-free 3-dimensional confocal imaging method for visualization of mouse intestine with subcellular-level resolution. Gastroenterology. 137(2): p453-465, 2009. PMID 19447107
  3. Fu YY, Peng SJ, Lin HY, Pasricha PJ, and Tang SC. 3-D imaging and illustration of mouse intestinal neurovascular complex. Am J Physiol Gastrointest Liver Physiol. 304(1):G1-11, 2013. PMID 23086917
  4. Fu YY, Lu CH, Lin CW, Juang JH, Enikolopov G, Sibley E, Chiang AS,Tang SC. Three-dimensional optical method for integrated visualization of mouse islet microstructure and vascular network with subcellular-level resolution. Journal of Biomedical Optics. 15(4), Article Number: 046018 (9 pages), 2010. PMID 20799820
  5. Fu YY and Tang SC. Optical clearing facilitates integrated 3D visualization of mouse ileal microstructure and vascular network with high definition. Microvascular Research, 80(3):512-21, 2010. PMID 20600164
  6. Fu YY, Sibley E, and Tang SC. Transient cytochalasin-D treatment induces apically administrated rAAV2 across tight junctions for transduction of enterocytes. Journal of General Virology. 89: p3304-3308, 2008. PMID 19008386
  7. Tang SC, Fu YY, Lo WF, Hua TE, and Tuan HY. Vascular labeling of luminescent gold nanorods enables 3-D microscopy of mouse intestinal capillaries. ACS Nano, 4(10):6278-84, 2010. PMID 20886812
  8. Chiu YC, Hua TE, Fu YY, Pasricha PJ, and Tang SC. 3-D imaging and illustration of the perfusive mouse islet sympathetic innervation and its remodeling in injury. Diabetologia, 55(12):3252-61, 2012. PMID 22930160
  9. Yang WC, Huang YS, Chen YC, Fu YY, Tang SC, and Fu CC. Engineering a biomimetic villus array for in vitro three-dimensional culture of intestinal epithelial cells. IEEE/ASME Journal of Microelectromechanical Systems, 21(6):1418-1425. 2012.