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Conditions We Treat: Familial Adenomatous Polyposis

Familial adenomatous polyposis (FAP) is an inherited condition that affects the gastrointestinal tract. FAP leads to hundreds or thousands or polyps inside the colon or rectum. This condition is also known as hereditary polyposis of the colorectum, familial polyposis and Gardner’s syndrome.

Familial Adenomatous Polyposis (FAP): What You Need to Know

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  • FAP is a genetic condition in which hundreds or thousands of polyps develop in the colon or rectum. The polyps, if untreated, may progress into cancer.
  • If you or a family member has FAP, talk to your doctor about genetic counseling.
  • Johns Hopkins Colon Cancer Risk Assessment Clinic evaluates patients who are at risk for developing colon cancer.
  • Your doctor may recommend colorectal surgery to treat FAP.

The polyps begin to appear during teen years and often become cancerous by 40 years of age if left untreated. People with FAP have a 50 percent chance of passing the condition on to their children.

Genetic counseling is available and recommended for individuals with FAP and their families. A genetic counselor can explain how FAP is inherited and which family members are at risk for developing FAP and give you information regarding genetic testing. Learn more about our unique Colon Cancer Risk Assessment Clinic.

Patient Resources

To make an appointment with a member of the Johns Hopkins medical team or speak with someone at the Colorectal Cancer Risk Assessment Service, call 410-614-LIFE (5433).

Request an Appointment


Why choose Johns Hopkins Division of Gastroenterology and Hepatology for familial adenomatous polyposis?

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Our Physicians

Our specialists offer the latest treatment strategies for familial adenomatous polyposis.

Meet our physicians:
Dr. Frank Giardiello

Our Research

The findings of a Johns Hopkins researcher is leading to new and important knowledge about serrated polyposis.

Read about the research findings.