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Cystic Fibrosis Linkage Analysis

Genes:
CFTR

Test Information

Test Method

Linkage analysis by PCR of dinucleotide repeats, 3 flanking markers; recombination frequency ranges from <1% to 5%.   

Clinical Sensitivity

Depends on the informativeness of the markers and the pedigree structure of the family.    

Sample Requirements

3-6ml whole blood in EDTA (purple topped) tubes. (see Pediatric or Adult blood sample algorithms for additional information)

We prefer whole blood for all tests.

Turn Around Time

Approximately 2 weeks from the time all necessary samples are received

Fee and CPT Codes

$344 per individual blood sample

CPT Code: 81479 

Special Considerations

Please call the laboratory genetic counselor prior to submitting a family for linkage analysis.

A clinical data form is required for each affected individual in the family. Download the form here.

INFORMED CONSENT from the patient is required prior to ordering a genetic test. The DNA Diagnostic Lab's consent is located on the second page of the requisition form. There is also a patient brochure, "Things Every Patient Should Know Before Consenting to a Genetic Test", available for download.