Transgender women needed for a research study that involves taking daily observed doses of the HIV drug Truvada, along with Lupron injections and oral estrogen. This research involves multiple study visits, including 5 separate day-long visits for blood and colon tissue sampling.

Basic Study Requirements:

• Over 18 years of age
• HIV negative
• Transgender women not currently on hormones or willing to temporarily stop hormone therapy
• Willing to come in for 5 day-long visits at the Johns Hopkins Hospital
• Willing to come to Johns Hopkins for daily observed Truvada dosing

Earn up to $3,650.
If interested, call 443-287-7156.
Principal Investigator: Mark Marzinke, Ph.D.
Protocol Number: IRB00203162
Approved February 26, 2019.

Protocol Title: A Phase 1, Open-Label, Single-Arm, Single-Dose Study to Evaluate the Pharmacokinetics and Distribution of Long-Acting HIV Capsid Inhibitor, Lenacapavir (LEN), into Rectal and Female Genital Tract Tissues in HIV-Seronegative Participants

Healthy adults needed for a research study for an investigational HIV prevention medication (PrEP), for HIV negative individuals.

Basic Study Requirements:

• Healthy male or female 18-50 years of age
• HIV negative
• Are not regularly taking a prescription medication other than contraception OR willing to have their medication list reviewed by study investigator
• Willing to come in for multiple clinic visits over 9 months
• Willing to have colon, vaginal and/or cervical biopsies collected

Qualified study participants may receive compensation for study time and travel up to $2,600 for men and up to $3,300 for women upon completion of this 9-month study for study related time and travel.

If you think you may be eligible and are interested in participating please call 410-614-2724 or email [email protected].

Principal Investigator: Craig Hendrix, MD

Protocol Number: IRB00249213

Summary: Researchers need healthy adult male volunteers with type O+ blood to study malaria parasites and to sustain mosquito colonies used in crucial malaria research

Announcement: Researchers need healthy adult male volunteers with type O+ blood to study malaria parasites and to sustain mosquito colonies used in crucial malaria research. This study involves a blood draw about every eight weeks, and participants will be paid $50 at each visit.

You may qualify if you:

• Are 18 or older
• Have O+ blood type
• Have not traveled to or lived in a malaria endemic area in the past 10 years
• Are not regularly taking a prescription or over-the-counter medication
• Are willing to undergo multiple blood draws

If you think you may be eligible and are interested in participating, call 443-287-7156 or email [email protected].

Principal investigator: Theresa Shapiro, MD, PhD

Protocol number: NA_00019050.

Contact Name: Drug Development Unit

Contact Email: [email protected]

Phone: 443-287-7156

VANC – awaiting IRB approval

Healthy adults are needed for a research study focusing on the hypersensitivity to Vancomycin. The study includes two parts, you can join one or both.

Part 1: Phone-call visit to confirm eligibility and collect medical history, followed by blood sample collection which can be either at Johns Hopkins Bayview Medical Center, at Johns Hopkins Hospital, or at home with a special kit.

Part 2: Phone-call visit to confirm eligibility and collect medical history, followed by a skin test at the Johns Hopkins Bayview Medical Center or at Johns Hopkins Hospital

Basic study requirements:

• Healthy nonpregnant adults between the ages 18-80
• Either have taken and tolerated vancomycin or have had an allergic reaction to vancomycin
• Do not currently have any systemic infections or major medical problems
• No use of systemic corticosteroids, cytotoxic, or immunosuppressive drug therapies within the past 60 days.
• No use of antihistamine in the week prior to the visit
• No use of adrenergic drugs or vasopressors 24 hours prior to the visit.

Qualified study participants who complete the study can make $35 for part 1 and $70 for part 2. Reimbursement for travel cost will be provided as appropriate.

If you think you may be eligible and are interested in participating, please call at 410-614-2724 or email at [email protected]

Principle investigator: Santiago Alvarez Arango, MD

Protocol Number: IRB00153292