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Stop BSI

For generations, central line-associated bloodstream infections (CLABSIs) were considered an inevitable outcome of health care. Yet a program developed at The Johns Hopkins Hospital, and later spread to ICUs in Michigan, showed that CLABSIs were entirely preventable when caregivers follow simple steps backed by evidence and fostered a culture of safety.

From these earlier successes emerged On the CUSP: Stop BSI, a four-year effort spanning 44 participating U.S. states. Through funding from the Agency for Healthcare Research and Quality (AHRQ) and in partnership with the Health Research and Educational Trust and the Keystone Center for Patient Safety and Quality of the Michigan Health & Hospital Association, the Armstrong Institute implemented the Comprehensive Unit-based Safety Program (CUSP) and interventions to prevent bloodstream infections nationwide.

More than 1,100 adult ICUs took part in the project, which concluded in September 2012.


Preliminary study findings released in September 2012 indicate that Stop BSI:

  • Reduced the rate of bloodstream infections in ICUs by 40 percent
  • Saved more than 500 lives and prevented more than 2,000 bloodstream infections
  • Averted $34 million in health care costs

Learn More

These resources from the project were created to help hospitals reduce CLABSIs:

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