Skip Navigation

Find a Research Lab

Research Lab Results for blood

Displaying 21 to 30 of 36 results
Results per page:
  • Nicholas Flavahan Lab

    Lab Website

    The Nicholas Flavahan Lab primarily researches the cellular interactions and subcellular signal...ing pathways that control normal vascular function and regulate the initiation of vascular disease. We use biochemical and molecular analyses of cellular mediators and cell signaling mechanisms in cultured vascular cells, while also conducting physiological assessments and fluorescent microscopic imaging of signaling systems in isolated blood vessels. A major component of our research involves aterioles, tiny blood vessles that are responsible for controlling the peripheral resistance of the cardiovascular system, which help determine organ blood flow. view more

    Research Areas: biochemistry, Raynaud's phenomenon, vascular biology, vasospasms
  • Obesity Hypertension Clinic: Reversing the Negative Cardiovascular Effects of Weight (ReNEW)

    Lab Website
    Principal Investigator:
    Tammy Brady, M.D., Ph.D.
    Medicine
    Pediatrics

    Hypertension in children is a major cause of disease, including early onset heart disease. Up t...o 25% of children who are overweight or obese have hypertension (high blood pressure), and children with obesity are at greater risk for having other cardiovascular disease risk factors such as high cholesterol and diabetes. The ReNEW Clinic at The Johns Hopkins University provides an innovative multidisciplinary approach to the evaluation and treatment of obesity-related hypertension to help prevent and treat cardiovascular disease. This clinic is designed for children with elevated blood pressure (prehypertension and hypertension) and a BMI at or above the 85th percentile. Many children in this clinic are enrolled in a longitudinal registry to help researchers learn how to better care for children with multiple risk factors for heart disease.

    Read more about the ReNEW clinic: Childhood Obesity: A Focus on Hypertension

    view more

    Research Areas: obesity, hypertension, pediatric cardiology
  • Paul Rothman Lab

    Lab Website
    Principal Investigator:
    Paul Rothman, M.D.
    Medicine

    Research in the Paul Rothman Lab has focused on cytokines. We’ve investigated the role these mo...lecules play in the normal development of blood cells as well as the abnormal blood-cell development that leads to leukemia. We’ve also studied the function of cytokines in immune system responses to asthma and allergies. view more

    Research Areas: leukemia, asthma, allergies, cytokines, immune system
  • Peter Abadir Lab

    Principal Investigator:
    Peter Abadir, M.D.
    Medicine

    Research in the Peter Abadir Lab focuses on the renin-angiotensin system (RAS), a signaling pat...hway that regulates blood pressure and has been linked independently to both aging and inflammation. We’re particularly interested in changes in RAS that occur with aging. We also study signal transduction and the role of the crosstalk between angiotensin II receptor in aging and are interested in understanding the function of angiotensin II in the process of vascular aging. view more

    Research Areas: renin-angiotensin system, aging, inflammation, gerontology
  • Peter Agre Lab

    Principal Investigator:
    Peter Agre, M.D.
    Biological Chemistry

    Work in the Peter Agre Lab focuses on the molecular makeup of human diseases, particularly mala...ria, hemolytic anemias and blood group antigens. In 2003, Dr. Agre earned the Nobel Prize in Chemistry for discovering aquaporin water channels. Building on that discovery, our recent research has included studies on the protective role of the brain water channel AQP4 in murine cerebral malaria, as well as defective urinary-concentrating ability as a result of a complete deficiency in aquaporin-1. We also collaborate on scientific training and research efforts with 20 Baltimore-area labs and in field studies in Zambia and Zimbabwe. view more

    Research Areas: infectious disease, anemia, malaria
  • Pluznick Lab

    Lab Website
    Principal Investigator:
    Jennifer Pluznick, Ph.D.
    Physiology

    The Pluznick Lab is interested in the role that chemosensation plays in regulating physiologica...l processes, particularly in the kidney and the cardiovascular system. We have found that sensory receptors (olfactory receptors, taste receptors, and other G-protein coupled receptors) are expressed in the kidney and in blood vessels, and that individual receptors play functional roles in whole-animal physiology. We are currently working to identify the full complement of sensory receptors found in the kidney, and are working to understand the role that each receptor plays in whole-animal physiology by using a variety of in vitro (receptor localization, ligand screening) and in vivo (whole-animal physiology) techniques. view more

    Research Areas: sensory receptors, cardiovascular, physiology, chemosensation, renal
  • Richard John Jones Lab

    Principal Investigator:
    Richard Jones, M.D.
    Medicine

    The Richard J. Jones Lab studies normal and cancerous stem cells in order to make clinical impr...ovements in areas such as blood and marrow transplantation (BMT). We discovered one of the most common stem-cell markers, Aldefluor, which identifies cells based on their expression of aldehyde dehydrogenase 1 (ALDH1), and have used this marker to detect and characterize normal stem cells and cancer stem cells from many hematologic malignancies. We also developed post-transplant cyclophosphamide and effective related haploidentical BMT. view more

    Research Areas: enzymes, stem cells, blood and marrow transplantation, leukemia, cancer
  • Rita Kalyani Lab

    Principal Investigator:
    Rita Kalyani, M.D., M.H.S.
    Medicine

    Research in the Rita Kalyani Lab examines the decreased physical functioning observed in patien...ts with diabetes as they age. Through several ongoing epidemiological cohorts, we are investigating the association of high blood glucose and high insulin levels with accelerated muscle loss, and possible contributions to the physical disability observed in diabetes. We are currently involved in clinical studies that aim to understand the underlying mechanisms for these associations and to facilitate the development of novel strategies to prevent muscle loss and disability in people with diabetes. view more

    Research Areas: metabolism, insulin, diabetes, cardiovascular diseases, endocrinology, blood glucose
  • Romsai Boonyasai Lab

    Lab Website
    Principal Investigator:
    Romsai Boonyasai, M.D., M.P.H.
    Medicine

    Research in the Romsai Boonyasai Lab focuses on systems-based approaches for improving health c...are quality, including reducing harm during care transitions after hospital discharge and improving outcomes related to hypertension and other chronic diseases. We recently have focused on developing and evaluating practice-based tools for improving the accuracy of blood pressure measurement, overcoming clinical inertia to treatment, and engaging patients in self-management of their health. view more

    Research Areas: health care quality, hypertension, care coordination, chronic illnesses
  1. 1
  2. 2
  3. 3
  4. 4
Create lab profile
Edit lab profile
back to top button