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Brain Tumor Research

The goal of brain cancer research at Johns Hopkins is advancing the understanding of brain tumors and creating a fertile environment for innovation and implementation of new therapies to improve survival and quality of life for our patients.
Comprising a large range of national and international experts with multidisciplinary expertise, Johns Hopkins brain cancer laboratories are where creative and curious minds can take the risks that true innovation demands.
Our team includes:
- The inventor of intraoperative chemotherapy delivery
- Principle investigators of National Cancer Institutes (NCI)-founded consortium in new approaches to brain tumor therapy
- World leaders in brain tumor pathology
- Researchers who have linked glioblastoma to the MGMT gene
- A dedicated research methodologist/statistician
Johns Hopkins is uniquely positioned to advance the modern science of new therapies, genomics, immunology, drug delivery systems and more. Researchers find the infrastructure and support they need to tailor scientific projects that evolve more easily into FDA-compliant clinical trials.
Our researchers are free to use all the tools essential to advancing the field, combining science and surgery, pharmacology, immunotherapy, stem cell research and gene sequencing, supported by close collaboration with Johns Hopkins’ Brain Science Institute and other centers.
No wonder Johns Hopkins is a perennial world leader in novel brain tumor treatments such as immunotherapy and direct delivery chemotherapy.
More breakthroughs are likely: New studies are finding targets for therapies to take on the most aggressive brain tumors, delving into the “skeletal” cell components of high-grade glioma and medulloblastoma. We are finding novel therapies and engineering ways to get these compounds across the blood-brain barrier.
Brain cancer research at Johns Hopkins is not just a place where scientific pioneers grow and thrive. Likewise, our Brain Tumor Center (designated by the NCI as a Comprehensive Cancer Center) is a beacon for patients with aggressive or complex tumors. At Johns Hopkins, numerous clinical trials are testing brand new treatments and experimental therapies available nowhere else.
Related Articles & Press Releases
- New Hope for Early Cancer Screen
- Triple Therapy Revs Up Immune System Against Common Brain Tumor
- Human Fat: A Trojan Horse to Fight Brain Cancer?
- Brain Tumor Cells Penetrated by Tiny, Biodegradable Particles Carrying Genetic Instructions
- There’s Life After Radiation for Brain Cells
- Johns Hopkins Researchers Find Promising Therapeutic Target for Hard-to-treat Brain Tumor
- Johns Hopkins Researchers Erase Human Brain Cell Tumors in Mice
- Common Genetic Pathway Could Be Conduit to Pediatric Tumor Treatment
- Brain Tumor Cells Penetrated by Tiny, Biodegradable Particles Carrying Genetic Instructions
- Triple Therapy Revs Up Immune System Against Common Brain Tumor
Researchers
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Renyuan Bai, M.B.B.S., Ph.D.
Associate Professor of Neurosurgery
Expertise, Disease and Conditions:View Full Profile -
Chetan Bettegowda, M.D., Ph.D.
Professor of Neurosurgery
Co-Director, Trigeminal Neuralgia CenterExpertise, Disease and Conditions: Stereotactic Radiosurgery, Spinal Tumors, Meningiomas, Pituitary Tumors, Cy... [more]View Full Profile -
Henry Brem, M.D.
Professor of Neurosurgery
Co-Director, Brain Cancer Program, Sidney Kimmel Cancer CenterExpertise, Disease and Conditions: Skull Base Tumors, Brain Cancer, Brain Tumors, Gliomas, Glioblastoma, Neuro... [more]View Full Profile -
Gary Gallia, M.D., Ph.D.
Associate Professor of Neurosurgery
Director of Endoscopic and Minimally Invasive NeurosurgeryExpertise, Disease and Conditions: Chordomas, Esthesioneuroblastoma, Meningiomas, Glioblastoma, Clival Tumors,... [more]View Full Profile -
Stuart Grossman, M.D.
Professor of Oncology
Co-Director, Brain Cancer Research Program, Sidney Kimmel Cancer CenterExpertise, Disease and Conditions: Pain Management, Medical Oncology, Neuro-Oncology, Brain Tumors... [more]View Full Profile -
Matthias Holdhoff, M.D., Ph.D.
Associate Professor of Oncology
Expertise, Disease and Conditions: Brain Tumors, Brain Cancer, Primary Central Nervous System (CNS) lymphoma, ... [more]View Full Profile -
Lawrence Richard Kleinberg, M.D.
Associate Professor of Radiation Oncology and Molecular Radiation Sciences
Vice Chair of Clinical ResearchExpertise, Disease and Conditions: Brain Tumors, Image-Guided Radiation Therapy, Neurosurgery, Neurology, Radi... [more]View Full Profile -
John Joseph Laterra, M.D., Ph.D.
Professor of Neurology
Co-Director, Brain Cancer Program, Johns Hopkins Sidney Kimmel Comprehensive Cancer CenterExpertise, Disease and Conditions: Brain Tumors, Von Hippel-Lindau (VHL), Neurology... [more]View Full Profile -
David Lin, M.D., Ph.D.
Assistant Professor of Neurosurgery
Chief of Neurosurgery, Johns Hopkins Suburban HospitalExpertise, Disease and Conditions: Pituitary Tumors, Lumbar Spine Diseases, Spinal Stenosis, Trigeminal Neural... [more]View Full Profile -
Raj Mukherjee, M.D., M.P.H.
Assistant Professor of Neurosurgery
Director of Neurosurgical Oncology, Johns Hopkins Bayview Medical CenterExpertise, Disease and Conditions: Head and Neck Cancers, Sellar Tumors, CyberKnife and Stereotactic Radiosurg... [more]View Full Profile -
Kristin Janson Redmond, M.D., M.P.H.
Associate Professor of Radiation Oncology and Molecular Radiation Sciences
Expertise, Disease and Conditions: Pituitary Adenoma, Radiation Oncology, Metastatic Brain Tumors, Brain Tumor... [more]View Full Profile -
Gregory Riggins, M.D., Ph.D.
Professor of Neurosurgery
Irving J. Sherman Research ProfessorExpertise, Disease and Conditions:View Full Profile -
Betty Tyler
Associate Professor of Neurosurgery
Expertise, Disease and Conditions:View Full Profile -
Jon Weingart, M.D.
Professor of Neurosurgery
Director, Neurosurgical Operating RoomExpertise, Disease and Conditions: Cervical Degenerative Disc Disease, Stereotactic Biopsy, Chiari Malformatio... [more]View Full Profile -
Xiaobu Ye, M.D., M.S.
Associate Professor of Neurosurgery
Expertise, Disease and Conditions:View Full Profile
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