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Our Organization

Technology Development Pipeline

 

 

 

The Center for Point-of-Care Technologies Research for STDs is comprised of four cores: Administrative, Clinical Translation and Validation, Technology Development, and Technology Training and Dissemination. Our cores work collaboratively to identify promising emerging technologies and facilitate their translation along a development pipeline.  

Administrative Core

The Administrative Core is led by the Center’s Co-Principal Investigators, Drs. Gaydos and Manabe. Under their leadership, personnel in this core manage the Center’s communications, finances, partnerships, and reporting. They also ensure responsiveness to members of the research community who wish to access the Center and promote teambuilding and project integration within the Center. Oversight of the characterized specimen biorepository for technical developers and the Technology Watch Database are also provided by this core.

Clinical Translation and Validation Core

This core includes experts and resources from an adolescent ambulatory clinic at Cincinnati Children’s Hospital Medical Center, an urban Emergency Department at Johns Hopkins Hospital, and outpatient clinics in Uganda, a low-resource setting. The core’s aims include evaluating the diagnostic accuracy, usability, and acceptability of prototype point-of-care devices for STD diagnosis and evaluating the implementation of point-of-care devices, including end-users’ assessments of preference, acceptability, and usability.

Technology Development Core

Personnel in this core seek out research facilities, start-up companies, and large diagnostic companies whose technology could be applied to the rapid analysis of nucleic acid or protein targets and inform them about the opportunities within the STD point-of-care testing market and the support available through the Center.  Also, core personnel manage annual subaward solicitations to fund promising technologies under development. Systems bioengineering support is also provided through this core.

Technology Training and Dissemination Core

This core has three aims. The first is to train technology developers on STD care delivery processes and STD clinicians and clinic administrators on how to incorporate available STD point-of-care devices into the work flow. The second aim is to conduct focus groups that inform future STD point-of-care device needs assessments. The final aim is to disseminate the needs assessment results to inform future POC STD diagnostic development.