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School of Medicine
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Pulmonary and Critical Care Medicine Labs
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Neil Aggarwal Lab
Research interests in the Neil Aggarwal Lab include the onset and treatment of acute respiratory distress syndrome. We’re also interested in genotyping and acute lung injury. Recently, we conducted a comprehensive review comparing the diagnostic accuracy of established and emerging imaging modalities for cardiac sarcoidosis.
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Noah Lechtzin Lab
Research in the Noah Lechtzin Lab investigates several important aspects of cystic fibrosis (CF), including the impact of antibiotic-resistant bacterial infections in CF patients and new therapy options for individuals with CF. Our research into new CF therapies has included studies on home electronic symptom and lung function monitoring, transbronchial needle aspiration and bedside percutaneous endoscopic gastrostomy tube placement. We also explore the role of metabolic complications in CF patients by examining how the disease is impacted by factors such as vitamin D deficiency, osteoporosis and testosterone deficiency.
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Outcomes After Critical Illness and Surgery Group
The Outcomes After Critical Illness and Surgery Group is focused on understanding and improving patient outcomes after critical illness and surgery. Research projects include improving long-term outcomes research for acute respiratory distress syndrome/acute respiratory failure (ARDS/ARF) patients; examining the long-term outcomes for acute lung injury/acute respiratory distress syndrome (ALI/ARDS) patients; and evaluating the effects of lower tidal volume ventilation and other aspects of critical illness and ICU care on the long-term physical and mental health outcomes of ALI/ARDS patients.
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Pali Shah Lab
Research in the Pali Shah Lab focuses on lung transplants. Specifically, we’re interested in chronic rejection and quality and safety as they relate to lung transplants.
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Patrick Sosnay Lab
The Patrick Sosnay Lab conducts translational research on cystic fibrosis. We also study genotype-phenotype relationships in patients with cystic fibrosis.
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Paul M. Hassoun Lab
The Paul M. Hassoun Lab leads research on the source and treatment of pulmonary arterial hypertension in scleroderma.
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Peter Terry Lab
Work in the Peter Terry Lab deals primarily with ethical questions surrounding patientsÕ end-of-life care and decision making. We explore topics such as family involvement in health care decision making, informed consent in clinical medicine and effectiveness of palliative support care. Our team has investigated the development and validation of a family decision-making self-efficacy scale. Our research has also included exploring the ethics around the allocation of lifesaving resources during a disaster.
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Philip Smith Lab
Work in the Philip Smith Lab explores several key topics within the field of sleep medicine. We investigate the role of obesity and neural control in sleep-disordered breathing as well as the impact of metabolic function on sleep apnea. We also research the ways in which HIV and its treatments impact a patient’s sleep. Our studies have included the effects of HIV and highly active antiretroviral therapy (HAART) on both sleep and daytime function as well as the relationship between systemic inflammation and sleep apnea in men with HIV.
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Rachel Damico Lab
Work in the Rachel Damico Lab explores topics within the fields of vascular biology and pulmonary medicine, with a focus on acute lung injury and apoptosis in lung diseases. Our studies have included examining idiopathic and scleroderma-associated pulmonary arterial hypertension, vascular receptor autoantibodies, and the link between inflammation and the Warburg phenomenon in patients with pulmonary arterial hypertension. We have also researched the inhibitory factor of macrophage migration and its governing of endothelial cell sensitivity to LPS-induced apoptosis.
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Rashmi Nisha Aurora Lab
Work in the Rashmi Nisha Aurora Lab explores topics within the field of sleep medicine, with a focus on pulmonary diseases that are disruptive to sleep and the use of polysomnography for diagnosing sleep disorders. Our recent research has included studies on home sleep testing for sleep apnea patients, the relationship between sleep-disordered breathing and caffeine consumption, and how obstructive sleep apnea impacts type 2 diabetes in older adults. We also have an interest in critical care medicine and have conducted studies on the ongoing effects of traumatic brain injuries on sleep.