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Nephrology Labs

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  • C. John Sperati Lab

    Dr. Sperati’s group focuses on complement mediated kidney disorders, glomerular disease, and renal arterial disease secondary to fibromuscular dysplasia. His team has a particular interest in thrombotic microangiopathies involving the complement system.

    Research Areas: kidney diseases, fibromuscular dysplasia, hypertension, hyperaldosteronism, atherosclerosis

    Principal Investigator

    C. John Sperati, M.D., M.H.S.

    Department

    Medicine

  • Deidra Crews Lab

    Dr. Crews’ team focuses on health disparities in chronic kidney disease. We have studied how social determinants of health, such as poverty and healthful food access, affect disparities in kidney disease outcomes. Our research on end-stage renal disease includes studies of the best timing and environment to initiate dialysis among vulnerable populations.

    Research Areas: poverty, chronic kidney disease, health disparities

    Principal Investigator

    Deidra Crews, M.D.

    Department

    Medicine

  • Duvuru Geetha Lab

    Dr. Geetha’s team focuses on renal diseases in patients with systemic vasculitis as well as BK virus nephropathy in patients who have undergone renal transplant. Our studies include clinical trials on the effectiveness of rituximab versus cyclosporine in treating idiopathic membranous nephropathy and a multinational study of belimumab with azathioprine for maintaining remission of granulomatosis with polyangiitis and microscopic polyangiitis. We also have conducted research on the treatment of ANCA vasculitis, particularly in kidney transplant patients.

    Research Areas: granulomatosis with polyangiitis, kidney diseases, vasculitis, kidney transplants, Glomerulonephritis, nephrology

    Principal Investigator

    Duvuru Geetha, M.B.B.S.

    Department

    Medicine

  • Edward Kraus Lab

    Dr. Kraus’ team investigates the factors that impact the long-term success or failure of kidney transplants as well as barriers to nephrology care and transplants in minority populations. We research many topics dealing with kidney transplant rejection, including diagnostic criteria, infection risk and incompatibility factors. Our lab also has a longstanding interest in pancreas transplants and has conducted research to establish guidelines for diagnosing antibody-mediated rejection of pancreas allografts-updated Banff grading schema.

    Research Areas: kidney transplants, nephrology, health disparities, pancreas transplants

    Principal Investigator

    Edward Kraus, M.D.

    Department

    Medicine

  • Fawaz Al Ammary Lab

    Dr. Al Ammary’s research focuses on (1) increasing live kidney donation safely to ensure optimal outcomes for donors and (2) advancing utilization of digital health technology and electronic health records to impact the precision and value of health care for live kidney donors and kidney transplant recipients.

    Research Areas: international live kidney donors, telemedicine, kidney transplant outcomes, hypertension and kidney function in live kidney donors, live kidney donation, preventable readmissions

    Principal Investigator

    Fawaz Al Ammary, M.B.B.Ch., Ph.D.

    Department

    Medicine

  • Hamid Rabb Lab

    Dr. Rabb’s lab is involved in translational research aimed at understanding the molecular pathogenesis of kidney ischemia/reperfusion injury. The lab is interested in the development of novel treatments for kidney IRI.

    Research Areas: kidney diseases, kidney ischemia/reperfusion injuries, nephrology

    Principal Investigator

    Hamid Rabb, M.D.

    Department

    Medicine

  • Michelle M. Estrella Lab

    The Michelle M. Estrella Lab conducts epidemiological and translational studies of kidney disease. We are particularly interested in HIV-related kidney disease and also study kidney injury biomarkers to determine their utility in clinical practice.

    Research Areas: epidemiology, biomarkers, kidney diseases, HIV

    Principal Investigator

    Michelle M. Estrella

    Department

    Medicine

  • Mohamed Atta Lab

    Dr. Atta and his research team explore the epidemiological and clinical interventions of a variety of kidney diseases. Our goal is not only to advance the understanding of many kidney diseases but also to capitalize on novel discoveries of basic science to treat a wide range of rare and common kidney disorders.




    • Multi-international observational study of a rare form of amyloid (LECT2 amyloid) to understand its natural history with the ultimate interest of treating this condition.

    • Our group has launched a project investigating the impact of COVID19 on the kidney to identify risk factors influencing outcome across different clinical phenotypes

    • In collaboration with the Division of Infectious Diseases and the School of Public Health, our research has focused on the epidemiology of HIV and kidney disease. We also study clinical markers and contributing factors in the progression of kidney disease, and the association between kidney disease and h...eart disease.

    • Our research group is participating in a multicenter consortium serving as a clinical core site to study the pathogenesis of HIV-associated kidney disease by providing well-characterized clinical specimens and corresponding clinical and laboratory data.

    view more

    Research Areas: kidney diseases, HIV, hepatitis C

    Principal Investigator

    Mohamed Atta, M.B.B.Ch., M.D., M.P.H.

    Department

    Medicine

  • Morgan Grams Lab

    Dr. Morgan Grams and her colleagues are involved in a wide range of clinical research projects applying quantitative methods to multidimensional data to develop actionable clinical indicators. Along with Dr. Josef Coresh, Dr. Grams leads the Chronic Kidney Disease (CKD) Prognosis Consortium, a global consortium of over 200 investigators and >11 million participants (https://ckdpc.org). They have developed and validated several risk calculators that are now widely used in clinical practice (https://ckdpcrisk.org). She holds a joint appointment in the Bloomberg School of Public Health, where she is a member of the Center of Drug Safety and Effectiveness. Her research in pharmacoepidemiology leverages electronic health records from multiple countries to evaluate the risks and benefits of commonly used medications across the spectrum of kidney function. Together with her team, Dr. Grams also focuses on identifying targetab...le pathways or biomarkers that underlie the development of chronic kidney disease using multi-omic approaches.



    Dr. Grams received the 2019 Frederick Brancati Mentoring Award. Currently, four of her mentees are supported by NIH K awards. More of their research can be found here: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40940579/?sort=date&direction=descending
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    Research Areas: organ donors, hyperglycemia, biomarkers, chronic kidney disease, health disparities

    Lab Website

    Principal Investigator

    Morgan Grams, M.D., M.H.S., Ph.D.

    Department

    Medicine

  • Nada Alachkar Lab

    Dr. Alachkar's research focuses on recurrent glomerular diseases post kidney transplantation. In particular, she has been studying recurrent FSGS post kidney transplant in several, partially NIH funded, prospective research projects that focuses on circulating factors associate with recurrent FSGS and new therapies of recurrent FSGS; in addition to the outcome of the disease. Also, Dr. Alachkar is the Chair of Banff recurrent GN working group that focus on the pathological changes of recurrent GN.


    Dr. Alachkar's other research focus is incompatible living and diseases donor transplant. She has several ongoing research studies that focus on AMR and the outcome of patients with positive donor specific antibodies.

    Research Areas: Focal segmental glomerular sclerosis in the transplanted kidney, Recurrent glomerular diseases post kidney transplant, Incompatible kidney transplant

    Principal Investigator

    Nada Alachkar, M.D.

    Department

    Medicine

  • Sharon Turban Lab

    Research in the Sharon Turban Lab focuses on the effects of sodium and potassium on blood pressure and on kidney function. We lead the Chronic Kidney Disease-Potassium (CKD-K) clinical trial, funded by American Heart Association, which examines the benefits and safety of two levels of potassium intake in patients with kidney disease. Other research includes the Chronic Renal Insufficiency Cohort (CRIC) study, which aims to improve the understanding of chronic kidney disease and related cardiovascular illness.

    Research Areas: sodium, kidney diseases, potassium, chronic kidney disease, blood pressure

    Principal Investigator

    Sharon Turban, M.D.

    Department

    Medicine

  • Stephen Sozio Lab

    Dr. Sozio’s research focuses on 1) Clinical research related to chronic kidney disease and end stage renal disease, and 2) Educational research in undergraduate and graduate medical education.



    The Sozio lab pursues work related to stroke, cognitive impairment, manifestations of kidney disease, and systematic reviews on clinical topics, and collaborates on multiple projects with other key investigators. In particular, Dr. Sozio has been an active investigator in the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) Study, Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) Study, Chronic Renal Insufficiency Cohort (CRIC) Study, and work funded through the Agency for Healthcare Research and Quality (AHRQ) and Johns Hopkins Evidence-Based Practice Center. In addition, the Sozio lab performs studies at the UME and GME levels, investing in understanding learners’ mentorship, research, and transitional experiences.

    Research Areas: end stage renal disease (ESRD), epidemiology, kidney diseases, stroke

    Principal Investigator

    Stephen Sozio, M.D.

    Department

    Medicine

  • Tariq Shafi Lab

    Research in the Tariq Shafi Lab focuses on improving the care of kidney failure patients who are on dialysis. We’re developing methods to evaluate and estimate residual kidney function—a strong predictor of survival in dialysis patients—and identifying ways to halt the loss of residual kidney function. We’re also involved with the Choices for Healthy Outcomes in Caring for ESRD (CHOICE) study, which compares the effectiveness of common treatment strategies for patients with end stage renal disease (ESRD).

    Research Areas: end stage renal disease (ESRD), dialysis, kidney diseases

    Principal Investigator

    Tariq Shafi

    Department

    Medicine

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