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Cardiology Labs

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  • The Atlantic Cardiovascular Patient Outcomes Research Team - Atlantic C-PORT

    Our research is centered on the safety, efficacy and outcomes of PCI performed at hospitals without on-site cardiac surgery.

    Active projects:

    C-PORT Randomized Studies and Registries; New Jersey Angioplasty Demonstration Project; InCar-decision support tools for performance of PCI at hospitals without on-site cardiac surgery.

    For more information please visit Cport.org.

    Research Areas: cardiac surgery, cardiology

    Principal Investigator

    Thomas Aversano, M.D.

    Department

    Medicine

  • The Barouch Lab

    The Barouch Lab is focused on defining the peripheral cardiovascular effects of the adipocytokine leptin, which is a key to the understanding of obesity-related cardiovascular disease. Interestingly, many of the hormonal abnormalities seen in obesity are mimicked in heart failure. The research program will enhance the understanding of metabolic signaling in the heart, including the effects of leptin, exercise, sex hormones, and downstream signaling pathways on metabolism and cardiovascular function.

    The lab also is working to determine the precise role of the “metabolic” beta-3 adrenergic receptor (ß3AR) in the heart and define the extent of its protective effect in obesity and in heart failure, including its role in maintaining nitric oxide synthase (NOS) coupling. Ultimately, this work will enable the exploration of a possible therapeutic role of ß3AR agonists and re-coupling of NOS in preventing adverse ventricular remodeling in obesity and in heart failure.

    Lili Barouch, MD,... is an associate professor of medicine in the Division of Cardiology and a member of the Advanced Heart Failure and Cardiac Transplantation group at the Johns Hopkins University School of Medicine. view more

    Research Areas: cardiac remodeling, cardiac hypertrophy, obesity, cognitive heart failure

    Principal Investigator

    Lili Barouch, M.D.

    Department

    Medicine

  • Weiss Lab

    The Weiss Lab, which features a multi-disciplinary team at Johns Hopkins as well as at Cedars Sinai Medical Center in Los Angeles, is dedicated to identifying the most important clinical, genetic, structural, contractile and metabolic causes of sudden cardiac death as well as the means to reverse the underlying pathology and lower risk.

    Current projects include research into energy metabolism in human heart failure and creatine kinase metabolism in animal models of heart failure.

    Robert G. Weiss, MD, is professor of medicine, Radiology and Radiological Science, at the Johns Hopkins University.

    Research Areas: energy metabolism, creatine kinase metabolism, imaging, heart failure, aging, cardiology, sudden cardiac death

    Lab Website

    Principal Investigator

    Robert Weiss, M.D.

    Department

    Medicine

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