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Huang, Hu

Hu Huang

Research Associate

The Wilmer Eye Institute
The Johns Hopkins School of Medicine


Hu Huang, Ph.D., is currently a research associate at the Wilmer Eye Institute, Johns Hopkins University School of Medicine. He received a Ph.D. degree in Biochemistry and Molecular Biology from Shanghai Institute of Biochemistry, Chinese Academy of Sciences. He completed his post-doctoral training with Dr. Robert Anderson at Oklahoma University and Dr. Ruben Adler at Johns Hopkins University.

Dr. Huang’s main research focus is on blinding retinal diseases including diabetic retinopathy, age-related macular degeneration and retinopathy of prematurity. His research goals are to decipher the biological pathways that underlie these eye diseases and discover target molecules that have therapeutic potential to treat the blinding eye diseases. Currently, Dr. Huang is conducting two research projects:

  • Role of placental growth factor in the pathogenesis of diabetic retinopathy. Dr. Huang developed a genetic model of diabetes: Akita.PlGF-/- diabetic mouse. With this novel mouse strain, he found that placental growth factor acts as a switch that controls the balance between protection and injury in diabetic retina. He is elucidating the mechanisms that placental growth factor and vascular endothelial growth factor receptor 1 (the only known receptor for placental growth factor) signaling is involved in the pathology of diabetic retinopathy.

  • Role of cytokine/chemokine signaling in pathogenesis of age-related macular degeneration. By using laser capture microdissection-isolated choroidal neovascularization, Dr. Huang discovered several new cytokine/chemokine genes relevant to age-related macular degeneration. The aged mice with genetic mutation of these genes develop characteristics similar to age-related macular degeneration in humans. He is characterizing whether these mouse models are robust models of age-related macular degeneration and elucidating the biological mechanisms of cytokine/chemokine-receptor signaling in the pathology of age-related macular degeneration.

Read Dr. Huang's CV

Dr. Sheila West on the Link Between Smoking and Eye Disease in Women - 7/23/2014

Dr. Pradeep Ramulu and Colleagues Study Relationship Between Vision Loss and Work Status - 7/18/2014

Wilmer Resident Receives Lindstrom Research Grant - 7/11/2014

Four Wilmer Researchers Receive BrightFocus Foundation Awards - 7/10/2014

Dr. Michael Repka Part of Team Researching Telemedicine and ROP - 6/27/2014

Dr. M. Valeria Canto-Soler and Colleagues Featured on WBAL-TV - 6/24/2014

Dr. M. Valeria Canto-Soler and Colleagues Use Human Stem Cells to Create Light-Sensitive Retina in a Dish - 6/10/2014

Wilmer's Division of Ocular Immunology Announces "Living With Uveitis" Support Group - 6/10/2014

Dr. Neil Bressler to Speak on Diabetic Retinopathy at National Eye Health Summit and Webcast - 6/10/2014

Dr. Donald Zack Receives a Research to Prevent Blindness Nelson Trust Award for Retinitis Pigmentosa - 6/9/2014

Dr. Michael Boland Leads Study on Effectiveness of Automated Telecommunication-Based Reminders on Adherence to Glaucoma Medication Dosing - 6/4/2014

Dr. Christina Prescott Discusses Summer Eye Protection on Fox 45 News - 6/1/2014

Dr. Jonathan Song Discusses Treatment Options for Pediatric Cataracts - 5/23/2014

Johns Hopkins' Jordan Green Discusses His Work at Wilmer's Translational Tissue Engineering Center - 5/21/2014

Longtime Wilmer Employee Lillie Alston Honored by Hopkins - 5/19/2014

Dr. Richard Semba: Diets Rich in Antioxidant Resveratrol Fail to Reduce Deaths, Heart Disease or Cancer - 5/12/2014

Dr. Neil Miller Explains Eye Twitching in The Wall Street Journal - 5/12/2014

Dr. Hendrik Scholl Receives ARVO Award - 5/7/2014


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