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James M. Tielsch, Ph.D.

tielsch

Professor & Associate Chair for Academic Programs
Department of International Health
The Bloomberg School of Public Health
Johns Hopkins University

Room W5009
615 N. Wolfe Street
Baltimore, MD 21205

Phone: 410-955-2436
Email: jtielsch@jhsph.edu

Education
PhD: Johns Hopkins University, School of Hygiene and Public Health
MHSc: Johns Hopkins University, School of Hygiene and Public Health
BS: University of Washington

Research Interests
My research interests focus on two major areas, the epidemiology and control of blinding ocular disease in the United States and in developing countries, and the epidemiology and control of micronutrient malnutrition among young children in developing countries with special emphasis on vitamin A, iron and zinc. Current research activities in the epidemiology of ocular disease include the Baltimore Eye Survey Follow-up Study, the Aravind Comprehensive Eye Survey (south India), the Baltimore Pediatric Eye Survey, and a number of other smaller studies. My interests cover the full range of studies involving epidemiologic methods in ophthalmology including basic descriptive epidemiologic studies of prevalence and incidence, etiologic research on risk factors for ocular disease, clinical trials of new treatments or community-based control strategies, screening, and health services research on inputs and outcomes of clinical management strategies on a population basis. Current research activities in micronutrient malnutrition include studies of the role of intestinal helminth infections on iron deficiency anemia and malnutrition in Zanzibar; the impact of iron and zinc supplementation on morbidity, growth, and motor and cognitive development of preschool age children in Zanzibar and Nepal; the impact of newborn vitamin A supplementation on early infant mortality and morbidity in south India; and the role of zinc and iron supplementation in reducing morbidity and mortality in Nepal. Other studies include community-based trials of newborn washing and umbilical cord care on neonatal mortality and morbidity in Nepal.

Representative Publications

1. Rein, DB, Zhang P, Wirth K, Lee PP, Hoerger TJ, McCall N, Klein R, Tielsch JM, Vijan S, Saadine J. The Economic Burden of Major Adult Visual Disorders in the United States. Archives of Ophthalmology 2006 (accepted for publication).

2. Iannotti LL, Tielsch JM, Black RE. Iron supplementation in early childhood: health benefits and risks. American Journal of Clinical Nutrition 2006 (accepted for publication).

3. Mullany LC, Darmstadt GL, Khatry SK, LeClerq SC, Tielsch JM. Relationship between the surrogate anthropometric measures, foot length and chest circumference, and birth weight among newborns of Sarlahi, Nepal. European Journal of Clinical Nutrition 2006 (accepted for publication).

4. Kavle JA, Khalfan SS, Stoltzfus RJ, Witter F, Tielsch JM, Caulfield LE. Measurement of blood loss at childbirth and postpartum. International Journal of Obstetrics and Gynecology 2006 (accepted for publication).

5. Mullany LC, Darmstadt GL, Katz J, Khatry SK, LeClerq SC, Tielsch JM. Risk factors for umbilical cord infection among newborns of southern Nepal. American Journal of Epidemiology 2006 (accepted for publication).

6. Goodman D, Haji HJ, Bickle QD, Stoltzfus RJ, Tielsch JM, Ramsan M, Savioli L, Albonico M. A comparison of methods for detecting the eggs of Ascaris, Trichuris, and hookworm in infant stool, and the epidemiology of infection in Zanzibari infants. American Journal of Tropical Medicine and Hygiene 2006 (accepted for publication).

7. Mullany LC, Darmstadt GL, Tielsch JM. Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countries. Pediatric Infectious Disease Journal 2006; 25:665-675.

8. Olney DK, Pollitt E, Kariger PK, Khalfan SS, Ali NS, Tielsch JM, Sazawal S, Black R, Allen LH, Stoltzfus RJ. Combined iron and folic acid supplementation with or without zinc reduces time to walking unassisted among Zanzibari infants 5-11 months old. Journal of Nutrition 2006; 136:2427-2434.

9. Mullany LC, Darmstadt GL, Coffey P, Khatry SK, LeClerq S, Tielsch JM. A low-cost, color-coded, hand-held spring scale accurately categorises birth weight in low-resource settings. Archives of Disease in Childhood 2006; 91:410-413.

10. Mullany LC, Darmstadt GL, Khatry SK, Katz J, LeClerq SC, Shrestha SR, Adhikari R, Tielsch JM. Topical applications of chlorhexidine to the umbilical cord prevent neonatal omphalitis and reduce mortality in southern Nepal: a community-based, cluster-randomized trial. Lancet 2006;136:2427-2434.

11. Tielsch JM, Khatry S, Stoltzfus RJ, Katz J, LeClerq S, Adhikari R, Mullany LC, Shresta S, Black R. Effect of routine prophylactic supplementation with iron and folic acid on preschool mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trial. Lancet 2006;367:144-152.

12. Mullany LC, Darmstadt GL, Khatry SK, LeClerq SC, Tielsch JM. Safety of neonatal skin cleansing in rural Nepal. Indian Pediatrics 2006;43:117-124.

13. Mullany LC, Darmstadt GL, Katz J, Khatry SK, LeClerq S, Adhikari R, Tielsch JM. Development of sign based algorithms for community-based assessment of omphalitis. Archives of Disease in Childhood Fetal Neonatal Ed 2006;91:99-104.

14. Siegel EH, Stoltzfus RJ, Khatry SK, LeClerq S, Katz J, Tielsch JM. Epidemiology of anemia among 4- to 17-month-old children living in south central Nepal. European Journal of Clinical Nutrition 2006;60:228-235.

15. Vittor AY, Gilman RH, Tielsch J, Glass G, Shields T, Lozano WS, Cancino VP, Patz JA. The effect of deforestation on the human-biting rate of Anopheles darlingi, the primary vector of Falciparum malaria in the Peruvian Amazon. American Journal of Tropical Medicine and Hygiene 2006;74:3-11.

16. Schein OD, McNally JJ, Katz J, Chalmers RL, Tielsch JM, Alfonso E, Bullimore M, O’Day D, Shovlin J. The incidence of microbial keratitis among wearers of a 30-day silicone Hydrogel extended-wear contact lens. Ophthalmology 2005;112:2172-2179.

17. Siegel EH, Stoltzfus RJ, Kariger P, Katz J, Khatry SK, LeClerq S, Pollitt E, Tielsch JM. Growth indices, anemia and diet independently predict motor milestone acquisition of infants in south central Nepal. Journal of Nutrition 2005;135:2840-2844.

18. Moulton LH, Rahmathullah L, Halsey NA, Thulasiraj RD, Katz J, Tielsch JM. Evaluation of non-specific effects of infant immunizations on early infant mortality in a southern Indian population. Tropical Medicine and International Health 2005; 10:1-9.

19. Cusick SE, Tielsch JM, Ramsan M, Jape JK, Sazawal S, Black RE, Stoltzfus RJ. Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool children. American Journal of Clinical Nutrition 2005;82:406-412.

20. West ES, Behrens A, McDonnell PJ, Tielsch JM, Herbert R, Schein OD. The incidence of endophthalmitis following cataract surgery among the US Medicare population increased between 1994-2001. Ophthalmology 2005;112:1388-1394.

21. Gedde SJ, Budenz DL, Haft P, Tielsch JM, Lee Y, Quigley HA. Factors influencing career choices among graduating ophthalmology residents. Ophthalmology 2005;112:1247-1254.

22. Kariger PK, Stoltzfus RJ, Olney D, Sazawal S, Black R, Tielsch JM, Frongillo EA, Khalfan SS, Pollitt E. Iron deficiency and physical growth predict attainment of walking but not crawling in poorly nourished Zanzibari infants. Journal of Nutrition 2005;135:814-819.

23. Semba RD, Ndugwa C, Perry RT, Clark TD, Jackson JB, Melikan G, Tielsch J, Mmiro F: Effect of periodic vitamin A supplementation on morbidity and mortality of human immunodeficiency virus-infected children in Uganda: a controlled clinical trial. Nutrition 2005;21:25-31.

24. Mullany LC, Darmstadt GL, Katz J, Khatry SK, Tielsch JM. Effect of instrument precision on estimation of low birth weight prevalence. Journal of Perinatology 2005;25:11-13.

25. Budenz DL, Chang RT, Huang X, Knighton RW, Tielsch JM. Reproducibility of retinal nerve fiber thickness measurements using the Stratus OCT in normal and glaucomatous eyes. Investigative Ophthalmology and Visual Science 2005;46:2440-2443.

26. Nirmalan PK, Tielsch JM, Katz J, Thulasiraj RD, Krishnadas R, Ramakrishnan R, Robin AL. Relationship between vision impairment and eye disease to vision-specific quality of life and function in rural India: The Aravind Comprehensive Eye Survey. Investigative Ophthalmology and Visual Science 2005;46:2308-2312.

27. Mullany LC, Darmstadt GL, Khatry SK, Tielsch JM. Traditional massage of newborns in Nepal: implications for trials of improved practice. Journal of Tropical Pediatrics 2005;51:82-86.

28. Nirmalan PK, Katz J, Robin AL, Ramakrishnan R, Krishnadas R, Thulasiraj RD, Tielsch JM . Female reproductive factors and eye disease in a rural south Indian population: The Aravind Comprehensive Eye Survey. Investigative Ophthalmology and Visual Science 2004;45:4273-4276.

29. Mebrahtu T, Stoltzfus RJ, Chwaya HM, Jape KJ, Savioli L, Montresor A, Albonico M, Tielsch JM. Low-dose daily iron supplementation for 12 months does not increase prevalence or density of malarial infections in young Zanzibari children. Journal of Nutrition 2004;134:3037-3041.

30. Robin AL, Nirmalan PK, Krishnadas R, Ramakrishnan R, Katz J, Tielsch J, Thulasiraj RD, Friedman DS. The utilization of eye care services by persons with glaucoma in rural south India. Transactions of the American Ophthalmological Society 2004;102:47-55.

31. Nirmalan PK, Katz J, Robin AL, Krishnadas R, Ramakrishnan R, Thulasiraj RD, Tielsch J. Utilization of eye care services in rural south India: The Aravind Comprehensive Eye Survey (ACES). British Journal of Ophthalmology 2004;88:1237-1241. .

32. Nirmalan PK, Katz J, Tielsch JM, Robin AL, Thulasiraj RD, Krishnadas R, Ramakrishnan R: Ocular trauma in a rural south Indian population: The Aravind Comprehensive Eye Survey. Ophthalmology 2004;111:1778-1781.

33. Nirmalan PK, Robin AL, Katz J, Tielsch JM, Thulasiraj RD, Krishnadas R, Ramakrishnan R. Risk factors for age-related cataract in a rural population of southern India: The Aravind Comprehensive Eye Study. British Journal of Ophthalmology 2004;88:989-994..

34. Tielsch JM, Beeche A: Impact of ivermectin on illness and disability associated with onchocerciasis. Tropical Medicine and International Health 2004;9(suppl):A45-A56.

35. The Eye Diseases Prevalence Research Group: The prevalence of cataract and pseudophakia/aphakia among adults in the United States. Archives of Ophthalmology 2004;122:487-494.

36. The Eye Diseases Prevalence Research Group: Causes and prevalence of visual impairment among adults in the United States. Archives of Ophthalmology 2004;122:477-485.

37. The Eye Diseases Prevalence Research Group: The prevalence of diabetic retinopathy among adults in the United States. Archives of Ophthalmology 2004;122:552-563.

38. The Eye Diseases Prevalence Research Group: The prevalence of open-angle glaucoma among adults in the United States. Archives of Ophthalmology 2004;122:532-538.

39. The Eye Diseases Prevalence Research Group: The prevalence of age-related macular degeneration in the United States. Archives of Ophthalmology 2004;122:564-572.

40. The Eye Diseases Prevalence Research Group: The prevalence of refractive errors among adults in the United States, Western Europe, and Australia. Archives of Ophthalmology 2004;122:494-505.

41. Nirmalan PK, Katz J, Robin AL, Tielsch JM, Namperlaswamy P, Kim R, Narendran V, Ramakrishnan R, Krishnadas R, Thulasiraj RD, Suan E: Prevalence of vitreo-retinal disorders in a rural population of southern India: The Aravind Comprehensive Eye Study. Archives of Ophthalmology 2004;122:581-586.

42. Glass TA, Freedman M, Carlson MC, Hill J, Frick KD, Ialongo N, McGill S, Rebok GW, Seeman T, Tielsch JM, Wasik BA, Zeger S, Fried LP. Experience corps: design of an intergenerational program to boost social capital and promote the health of an aging society. Journal of Urban Health. 2004;81:94-105.

43. Fried LP, Carlson MC, Freedman M, Frick KD, Glass TA, Hill J, McGill S, Rebok GW, Seeman T, Tielsch J, Wasik BA, Zeger S. A social model for health promotion for an aging population: initial evidence on the experience corps model. Journal of Urban Health. 2004;81:64-78.

44. Robin AL, Frick KD, Katz J, Budenz D, Tielsch JM. The ocular hypertension treatment study. Intraocular pressure lowering prevents the development of glaucoma, but does that mean we should treat before the onset of disease? Archives of Ophthalmology 2004;122:376-378.

45. Stoltzfus RJ, Chwaya HM, Montresor A, Tielsch JM, Jape JK, Albonico M, Savioli L: Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool children. Journal of Nutrition 2004; 134:348-356.

View Dr. Tielsch's Curriculum Vitae

 

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