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Stevens-Johnson Syndrome

Stevens-Johnson Syndrome
Stevens-Johnson Syndrome

Stevens-Johnson Syndrome (SJS) is a disorder that causes painful blisters and lesions on the skin and mucous membranes and can cause severe eye problems. The most common cause of SJS is an adverse allergic drug reaction. Almost any drug can result in SJS, but sulfa drugs are a particularly common cause. It is more common in children and younger adults, but can develop at any age. Typical ocular problems associated with SJS can include conjunctivitis, scarring of the conjunctiva, inflammation inside the eye (iritis), corneal blisters and perforation, which can potentially lead to permanent vision loss.  

Diagnosis:

Diagnosis is made on the clinical grounds by an expert ophthalmologist or dermatologist. A skin biopsy may be performed by a dermatologist in the acute phase of the disease for exact diagnosis.

Treatment:

Management of SJS is mainly supportive. Patients are admitted in the burn units during the acute phase. The therapy includes ocular lubrication with artificial tears and ointments and frequent surveillance of ocular infections. Corneal transplants, limbal stem cell transplantations or artificial corneal procedures maybe considered if advised by an ophthalmologist. The Ocular Surface Diseases and Dry Eye Clinic currently has a specialized contact lens service for patients that have a severe dry eye condition and eyelid/eyelash problems.

> Treated by the Ocular Surface Diseases and Dry Eye Clinic

Dr. Pradeep Ramulu and Colleagues Study Relationship Between Vision Loss and Work Status - 7/18/2014

Wilmer Resident Receives Lindstrom Research Grant - 7/11/2014

Four Wilmer Researchers Receive BrightFocus Foundation Awards - 7/10/2014

Dr. Michael Repka Part of Team Researching Telemedicine and ROP - 6/27/2014

Dr. M. Valeria Canto-Soler and Colleagues Featured on WBAL-TV - 6/24/2014

Dr. M. Valeria Canto-Soler and Colleagues Use Human Stem Cells to Create Light-Sensitive Retina in a Dish - 6/10/2014

Wilmer's Division of Ocular Immunology Announces "Living With Uveitis" Support Group - 6/10/2014

Dr. Neil Bressler to Speak on Diabetic Retinopathy at National Eye Health Summit and Webcast - 6/10/2014

Dr. Donald Zack Receives a Research to Prevent Blindness Nelson Trust Award for Retinitis Pigmentosa - 6/9/2014

Dr. Michael Boland Leads Study on Effectiveness of Automated Telecommunication-Based Reminders on Adherence to Glaucoma Medication Dosing - 6/4/2014

Dr. Christina Prescott Discusses Summer Eye Protection on Fox 45 News - 6/1/2014

Dr. Jonathan Song Discusses Treatment Options for Pediatric Cataracts - 5/23/2014

Johns Hopkins' Jordan Green Discusses His Work at Wilmer's Translational Tissue Engineering Center - 5/21/2014

Longtime Wilmer Employee Lillie Alston Honored by Hopkins - 5/19/2014

Dr. Richard Semba: Diets Rich in Antioxidant Resveratrol Fail to Reduce Deaths, Heart Disease or Cancer - 5/12/2014

Dr. Neil Miller Explains Eye Twitching in The Wall Street Journal - 5/12/2014

Dr. Hendrik Scholl Receives ARVO Award - 5/7/2014

 

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