Search the Health Library
Get the facts on diseases, conditions, tests and procedures.
I Want To...
Find a Doctor
I Want To...
Find Research Faculty
Enter the last name, specialty or keyword for your search below.
Detection and Diagnosis
If you notice the general symptoms of Fuchs Dystrophy, a visit to your doctor's office is recommended. At the office, your ophthalmologist will typically investigate these symptoms through three different methods: slit lamp microscopy, pachymetry and confocal microscopy.
Slit Lamp Microscopy
This instrument is found in the every ophthalmologist and optometrist’s office. Its name comes from the fact that its beam of light can be adjusted from a thin slit to a round circle, depending on what part of the eye the doctor wants to see.
When the doctor looks at the eye using a slit-lamp microscope, this is what he sees:
Full view of the eye. Note the thin beam of light shining on the eye (arrow). This patient does not have Fuchs Endothelial Corneal Dystrophy (FECD).
This is the same sort of view as the one to the left, but the photo has been taken closer up. This patient has advanced FECD.
View of the lens (this one is clear—no cataract) and the cornea. An arrow is pointing to the cornea. The greenish football shaped thing is the lens.
Side view of the cornea. This patient has FECD.
A retroillumination image of a healthy cornea. This view is always reddish because the light goes straight in and then bounces off the retina (which has lots of blood vessels in it).
Another retroillumination image of the cornea. This patient has advanced FECD.
An instrument called a pachymeter measures corneal thickness. This instrument is useful in resolving disorders that cause the cornea to thicken, such as Fuchs Dystrophy.
This patient does NOT have Fuchs Dystrophy.
In addition, we altered the corneal thickness reading upward (to 657 microns).
A doctor measuring a patient’s corneal thickness using a pachymeter.
|A confocal microscope uses a flashing light to take lots of pictures very quickly, one right after the other. This instrument is used to study the corneal endothelium. It measures the number, density, and shape of the endothelial cells. It magnifies them thousands of times. Pleomorphism (variations in shape), and guttae (dewdrop-like shapes that are signs of Fuchs) are easy to see thanks to the photographs that the confocal microscope produces.|
The pictures below were taken with a confocal microscope:
The beginnings of FECD (late-onset type).
Moderate FECD (late-onset type).
Advanced FECD (early-onset type).
To learn more about the different types (early- vs. late-onset) of FECD, follow the link to go to the section of this site entitled, Types of Fuchs Dystrophy.