Web notes  

July 2015
PUBLICATIONS - Back

Ophthalmology Archives

1. Pan Q, Xu Q, Boylan NJ, Lamb NW, G Emmert D, Yang JC, Tang L, Heflin T, Alwadani S, Eberhart CG, Stark WJ, Hanes J. Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats. J Control Release. 2015 Mar 10;201:32-40.
Key words: Corneal rejection; Corneal transplantation; Dexamethasone; Drug delivery; PLGA
http://www.ncbi.nlm.nih.gov/pubmed/25576786

2. Soiberman U, Pan Q, Daoud Y, Murakami P, Stark WJ. Iris suture fixation of subluxated intraocular lenses. Am J Ophthalmol. 2015 Feb;159(2):353-9. doi: 10.1016/j.ajo.2014.11.009.
Key words: intraocular lens; subluxation; iris suture fixation
http://www.ncbi.nlm.nih.gov/pubmed/25447110

3. Zigler, Jr. JS and Sinha D. ?A3/A1-crystallin: More than a lens protein. Prog Retin Eye Res. 2015 Jan; 44C: 62-85. doi: 10.1016/j.preteyeres.2014.11.002.
Key words: Astrocyte, lysosome, retinal pigment epithelial cell, signaling, bA3/A1-crystallin
http://www.ncbi.nlm.nih.gov/pubmed/25461968

1. Goldstein JE, Chun, MW, Fletcher DC, Deremeik JT, Massof RW, Low Vision Research Network Study Group. Visual ability of patients seeking outpatient services in the United States. JAMA Ophthalmol. 2014;132(10):1169-77.
Key words: low vision, outpatient, visual ability
http://www.ncbi.nlm.nih.gov/pubmed/25073745

2. Valapala M, Edwards M, Hose S, Grebe R, Bhutto IA, Cano M, Berger T, Mak TW, Wawrousek E, Handa JT, Lutty GA, Samuel Zigler J Jr, Sinha D. Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response. Aging Cell. 2014 Dec;13(6):1091-4.
Key words: Cryba1 cKO mice, inflammation, age-related macular degeneration, lipocalin-2, lysosomes
http://www.ncbi.nlm.nih.gov/pubmed/25257511

1. Cunningham ET Jr, Lowder CY, Miserocchi E, Thorne JE, Zierhut M. Sarcoid uveitis. Ocul Immunol Inflamm. 2014 Aug;22(4):253-6. doi: 10.3109/09273948.2014.941235.
Key words: sarcoidosis, uveitis, intraocular inflammation
http://www.ncbi.nlm.nih.gov/pubmed/25014115

2. Leung TG, Moradi A, Liu D, Nguyen QD, Dunn JP, Burkholder B, Butler NJ, Ostheimer T, Thorne JE.
Clinical features and incidence rate of ocular complications in punctate inner choroidopathy. Retina. 2014 Aug;34(8):1666-74.
Key words: choroidopathy, ocular complications, white spot syndromes
http://www.ncbi.nlm.nih.gov/pubmed/24743642

3. Ostheimer TA, Burkholder BM, Leung TG, Butler NJ, Dunn JP, Thorne JE. Tattoo-associated uveitis.
Am J Ophthalmol. 2014 Sep;158(3):637-43.e1.
Key words: uveitis, tattoo induration, sarcoidosis
http://www.ncbi.nlm.nih.gov/pubmed/24875002

4. Sen HN, Vitale S, Gangaputra SS, Nussenblatt RB, Liesgang TL, Levy-Clarke GA, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Kempen JH. Periocular corticosteroid injections in uveitis: effects and complications. Ophthalmology. 2014 Jul 11. pii: S0161-6420(14)00485-0.
Key words: corticosteroids, uveitis, complications, periocular injection, kenalog
http://www.ncbi.nlm.nih.gov/pubmed/25017415

1. Brown JC, Goldstein JE, Chan TL, Massof R, Ramulu P, Low Vision Research Network Study Group. Characterizing functional complaints in patients seeking outpatient low-vision services in the United States. Ophthalmology. 2014 Apr 23. pii: S0161-6420(14)00198-5.
Key words: low vision, complaints, reading
http://www.ncbi.nlm.nih.gov/pubmed/24768243

1. Moradi A, Amin RM, Thorne JE. The role of gender in juvenile idiopathic arthritis-associated uveitis.
J Ophthalmol. 2014;2014:461078.
Key words: JIA; Uveitis; Outcomes; Gender
http://www.ncbi.nlm.nih.gov/pubmed/24701346

2. Takakura A, Tessler HH, Goldstein DA, Guex-Crosier Y, Chan CC, Brown DM, Thorne JE, Wang R, Cunningham ET. Viral retinitis following intraocular or periocular corticosteroid administration: a case series and comprehensive review of the literature. Ocul Immunol Inflamm. 2014 Jun;22(3):175-82.
Key words: Retinitis; Infection; Side-effects of regional steroid use
http://www.ncbi.nlm.nih.gov/pubmed/24655372

3. Artornsombudh P, Pistilli M, Foster CS, Pujari SS, Gangaputra SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH. Factors predictive of remission of new-onset anterior uveitis. Ophthalmology. 2014 Mar;121(3):778-84. doi: 10.1016/j.ophtha.2013.09.041. Epub 2013 Dec 15.
Key words: Anterior uveitis; Remission; Treatment outcomes; Risk factors
http://www.ncbi.nlm.nih.gov/pubmed/24342020

4. Suhler EB, Lim LL, Beardsley RM, Giles TR, Pasadhika S, Lee ST, de Saint Sardos A, Butler NJ, Smith JR, Rosenbaum JT. Rituximab therapy for refractory orbital inflammation: results of a phase 1/2, dose-ranging, randomized clinical trial. JAMA Ophthalmol. 2014 Mar 20. doi: 10.1001/jamaophthalmol.2013.8179. [Epub ahead of print]
Key words: Rituximab, Orbital Inflammation, Thyroid Eye Disease, Treatment Response
http://www.ncbi.nlm.nih.gov/pubmed/24652467

1. Althoff KN, Rebeiro P, Brooks JT, Buchacz K, Gebo K, Martin J, Hogg R, Thorne JE, Klein M, Gill MJ, Sterling TR, Yehia B, Silverberg MJ, Crane H, Justice AC, Gange SJ, Moore R, Kitahata MM, Horberg MA; for the North American AIDS Cohort Collaboration on Research Design (NA-ACCORD). Disparities in the quality of HIV care when using US Department of Health and Human Services indicators. Clin Infect Dis. 2014 Feb 17. [Epub ahead of print]
Key words: Quality of care disparity; HIV care; North American AIDS Cohort Collaboration
http://www.ncbi.nlm.nih.gov/pubmed/24463281

2. Burkholder BM, Leung TG, Ostheimer TA, Butler NJ, Thorne JE, Dunn JP. Spectral domain optical coherence tomography findings in acute syphilitic posterior placoid chorioretinitis. J Ophthalmic Inflamm Infect. 2014 Jan 27;4(1):2. doi: 10.1186/1869-5760-4-2.
Key words: OCT findings, placoid chorioretinitis; syphilitic eye disease
http://www.ncbi.nlm.nih.gov/pubmed/24468306

3. Moradi A, Sepah YJ, Sadiq MA, Nasir H, Kherani S, Sophie R, Do DV, Nguyen QD. Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema.
World J Diabetes. 2013 Dec 15;4(6):303-309.
Key words: Diabetic Macular Edema, Diabetic Retinopathy, Anti Vascular endothelial growth factor agents, Aflibercept, EYLEA
http://www.ncbi.nlm.nih.gov/pubmed/24379921

4. Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler Jr JS, Sinha D. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/bA3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy. 2014; 10(3).
Key words: MTORC1, V-ATPase, autophagy, lysosomes, bA3/A1-crystallin
http://www.ncbi.nlm.nih.gov/pubmed/24468901

1. Artornsombudh P, Pistilli M, Foster CS, Pujari SS, Gangaputra SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH. Factors predictive of remission of new-onset anterior uveitis. Ophthalmology. 2013 Dec 14. pii: S0161-6420(13)00886-5. doi: 10.1016/j.ophtha.2013.09.041. [Epub ahead of print]
Key words: Anterior Uveitis, Treatment, Induction of Remission
http://www.ncbi.nlm.nih.gov/pubmed/24342020

2. Levin MH, Pistilli M, Daniel E, Gangaputra SS, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study. Incidence of visual improvement in uveitis cases with visual impairment caused by macular edema. Ophthalmology. 2013 Dec 11. pii: S0161-6420(13)00843-9. doi: 10.1016/j.ophtha.2013.09.023. [Epub ahead of print]
Key words: Uveitis, Macular Edema, Visual Improvement, Epidemiology
http://www.ncbi.nlm.nih.gov/pubmed/24332536

3. Leung TG, Thorne JE. Emerging drugs for the treatment of uveitis. Expert Opin Emerg Drugs. 2013 Dec;18(4):513-21. doi: 10.1517/14728214.2013.861417.
Key words: Uveitis, Biologic Therapy, Conventional Immunosuppression
http://www.ncbi.nlm.nih.gov/pubmed/24274613

1. Weinberg RS, Burkholder BB, Srikumaran D, Lee BS. Reply to: Inadvertent trypan blue posterior capsule staining during cataract surgery. Am J Ophthalmol. 2013 Nov;156(5):1069-70.
Key words: cataract, trypan blue posterior capsule staining

http://www.ncbi.nlm.nih.gov/pubmed/24138754

2. Leung TG, Thorne JE. Emerging drugs for the treatment of uveitis. Expert Opin Emerg Drugs. 2013 Dec;18(4):513-21. doi: 10.1517/14728214.2013.861417.
Key words: uveitis, immunosuppressive drug therapy, biologics
http://www.ncbi.nlm.nih.gov/pubmed/2427461

1. Baxter SL, Pistilli M, Pujari SS, Liesegang TL, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Kempen JH. Risk of choroidal neovascularization among the uveitides. Am J Ophthalmol. 2013 Sep;156(3):468-77.e2. doi: 10.1016/j.ajo.2013.04.040.
Key words: Uveitis, choroidal neovascularization, risk factors, SITE Study
http://www.ncbi.nlm.nih.gov/pubmed/23795984

2. Burkholder BM, Wang J, Dunn JP, Nguyen QD, Thorne JE. Postoperative outcomes after fluocinolone acetonide implant surgery in patients with birdshot chorioretinitis and other types of posterior and panuveitis. Retina. 2013 Sep;33(8):1684-93. doi: 10.1097/IAE.0b013e31828396cf.
Key words: Birdshot chorioretinitis, fluocinolone acetonide implants, ocular hypertension, post- operative outcomes
http://www.ncbi.nlm.nih.gov/pubmed/23549097

3. Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema.
Ophthalmology. 2013 Sep;120(9):1852-9.
Key words: Fluorescin angiography, uveitic macular edema, optical coherence
http://www.ncbi.nlm.nih.gov/pubmed/23706700

4. Lucas GM, Jing Y, Sulkowski M, Abraham AG, Estrella MM, Atta MG, Fine DM, Klein MB, Silverberg MJ, Gill MJ, Moore RD, Gebo KA, Sterling TR, Butt AA; NA-ACCORD of the IeDEA. Hepatitis C viremia and the risk of chronic kidney disease in HIV-infected individuals. J Infect Dis. 2013 Oct 15;208(8):1240-9.
Key words: HIV/AIDs, Hepatitis C, Kidney Disease, Infectious Disease
http://www.ncbi.nlm.nih.gov/pubmed/23904290

1. Lerman MA, Burnham JM, Chang PY, Daniel E, Foster CS, Hennessy S, Jabs DA, Joffe MM, Oktay Kacmaz R, Levy-Clarke GA, Mills MD, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH. Response of pediatric uveitis to tumor necrosis factor-? inhibitors. J Rheumatol. 2013 Aug;40(8):1394-1403.
Key words: pediatric uveitis, tumor necrosis factor- ?
http://www.ncbi.nlm.nih.gov/pubmed/23818712

2. Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema. ophthalmology. 2013 May 21. doi:pii: S0161-6420(13)00115-2. 10.1016/j.ophtha.2013.01.069. [Epub ahead of print]
Key words: fluorescein, angiography, optical coherence tomography, uveitic macular edema
http://www.ncbi.nlm.nih.gov/pubmed/23706700

3. Salek SS, Leder HA, Butler NJ, Gan TJ, Dunn JP, Thorne JE. Periocular triamcinolone acetonide injections for control of intraocular inflammation associated with uveitis. Ocul Immunol Inflamm. 2013 Aug;21(4):257-63. doi: 10.3109/09273948.2013.767353.
Key words: periocular triamcinolone acetonide, intraocular inflammation, uveitis
http://www.ncbi.nlm.nih.gov/pubmed/23617776

1. Salek SS, Leder HA, Butler NJ, Gan TJ, Dunn JP, Thorne JE. Periocular triamcinolone acetonide injections for control of intraocular inflammation associated with uveitis. Ocul Immunol Inflamm. 2013 Apr 25. [Epub ahead of print]
Key words: periocular triamcinolone acetonide, intraocular inflammation, uveitis
http://www.ncbi.nlm.nih.gov/pubmed/23617776

2. Suhler EB, Lowder CY, Goldstein DA, Giles T, Lauer AK, Kurz PA, Pasadhika S, Lee ST, de Saint Sardos A, Butler NJ, Tessler HH, Smith JR, Rosenbaum JT. Adalimumab therapy for refractory uveitis: results of a multicentre, open-label, prospective trial. Br J Ophthalmol. 2013 Apr;97(4):481-6. doi: 10.1136/bjophthalmol-2012-302292.
Key words: adalimumab, refractory uveitis
http://www.ncbi.nlm.nih.gov/pubmed/23376607

3. Valapala M, Hose S, Gongora C, Dong L, Wawrousek EF, Zigler Jr JS, Sinha D. Impaired endolysosomal function disrupts Notch signaling in optic nerve astrocytes. Nat Commun. 2013; 4: 1629.
Key words: Astrocytes, Notch signaling, g-secretase, bA3/A1-crystallin, Endolysosomes http://www.ncbi.nlm.nih.gov/pubmed/23535650

1. Burkholder BM, Wang J, Dunn JP, Nguyen QD, Thorne JE. Postoperative outcomes after fluocinolone acetonide implant surgery in patients with birdshot chorioretinitis and other types of posterior and panuveitis. Retina 2013 March 30 (epub ahead of print).
Key words: fluocinolone acetonide, chorioretinitis, panueveitis
http://www.ncbi.nlm.nih.gov/pubmed/23549097

1. Burkholder BM, Srikumaran D, Nanji A, Lee B, Weinberg RS. Inadvertent trypan blue posterior capsule staining during cataract surgery. Amer J Ophthalmol. 2013 Apr; 155(4): 625-628.
Key words: cataract, tryptan blue

http://www.ncbi.nlm.nih.gov/pubmed/23219064

1. Althoff KN, Buchacz K, Hall HI, Zhang J, Hanna DB, Rebeiro P, Gange SJ, Moore RD, Kitahata MM, Gebo KA, Martin J, Justice AC, Horberg MA, Hogg RS, Sterling TR, Cescon A, Klein MB, Thorne JE, Crane HM, Mugavero MJ, Napravnik S, Kirk GD, Jacobson LP, Brooks JT; North American AIDS Cohort Collaboration on Research and Design. U.S. trends in antiretroviral therapy use, HIV RNA plasma viral loads, and CD4 T-lymphocyte cell counts among HIV-infected persons, 2000 to 2008. Ann Intern Med. 2012 Sep 4;157(5):325-35.
Key words: antiretroviral therapy, HIV, RNA, lymphocytes
http://www.ncbi.nlm.nih.gov/pubmed/22944874

2. Butler NJ, Thorne JE. Current status of HIV infection and ocular disease. Curr Opin Ophthalmol. 2012 Nov;23(6):517-22. doi: 10.1097/ICU.0b013e328358ba85.
Key words: HIV infection, ocular disease
http://www.ncbi.nlm.nih.gov/pubmed/23047168

3. Daniel E, Pistilli M, Pujari SS, Kaçmaz RO, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Kempen JH. Risk of hypotony in noninfectious uveitis. Ophthalmology. 2012 Nov;119(11):2377-85. doi: 10.1016/j.ophtha.2012.05.032. Epub 2012 Jul 13.
Key words: hypotony, uveitis
http://www.ncbi.nlm.nih.gov/pubmed/22796306

4. Gangaputra S, Drye L, Vaidya V, Thorne JE, Jabs DA, Lyon AT; Studies of the Ocular Complications of AIDS (SOCA) Research Group. Non-cytomegalovirus ocular opportunistic infections in patients with AIDS. Am J Ophthalmol. 2012 Oct 12. doi:pii: S0002-9394(12)00516-8. 10.1016/j.ajo.2012.07.019. [Epub ahead of print]
Key words: non-cytomegalovirus infections, AIDS, ocular opportunistic infections
http://www.ncbi.nlm.nih.gov/pubmed/23068916

5. Gregory AC 2nd, Kempen JH, Daniel E, Kaçmaz RO, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE; Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study Research Group. Risk factors for loss of visual acuity among patients with uveitis associated with juvenile idiopathic arthritis: The Systemic Immunosuppressive Therapy for Eye Diseases Study. Ophthalmology. 2012 Oct 11. doi:pii: S0161-6420(12)00687-2. 10.1016/j.ophtha.2012.07.052. [Epub ahead of print]
Key words: visual acuity, uveitis, juvenile idiopathic arthritis, eye diseases
http://www.ncbi.nlm.nih.gov/pubmed/23062650

6. Kozak I, Ahuja A, Gangaputra S, Van Natta ML, Thorne JE, Freeman WR. Optic nerve head morphology and visual field function in patients with AIDS and without infectious retinitis. Ocul Immunol Inflamm. 2012 Oct;20(5):342-8. doi: 10.3109/09273948.2012.694552. Epub 2012 Jun 14.
Key words: optic nerve, visual field function, AIDS, infectious retinitis
http://www.ncbi.nlm.nih.gov/pubmed/22697270

1. Bhutto I, Lutty GA. Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex. Molecular Aspects of Medicine 2012;33:295-317.
Key words: retinal pigment epithelium, Bruch's membrane, choriocapillaris complex
No PMID available

2. Geruschat DR, Bittner AK, Dagnelie G. Orientation and mobility assessment in retinal prosthetic clinical trials. Optom Vis Sci. 2012 Sep;89(9):1308-15.
Key words: prosthetic vision, orientation and mobility, low vision, retinal chip implant, low-vision rehabilitation
http://www.ncbi.nlm.nih.gov/pubmed/22902422

3. Padula W, Singman E, Vicci V, Munitz R, Magrun WM. Evaluating and Treating Visual Dysfunction. Chapter 45 in Brain Injury Medicine, 2nd Ed. Demos Medical Publishing. 2012.

4. Shao H, Lee S, Gae-Scott S, Nakata C, Chen S, Hamad AR, Chakravarti S. Extracellular matrix lumican promotes bacterial phagocytosis and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity. J Biol Chem. 2012 Oct 19;287(43):35860-72.
http://www.ncbi.nlm.nih.gov/pubmed/22865855

1. Goldstein JE, Massof RW, Deremeik JT, Braudway S, Jackson ML, Kehler KB, Primo SA, Sunness JS, Low Vision Research Network Study Group. Baseline traits of low vision patients served by private outpatient clinical centers in the United States. Arch Ophthalmol 2012 Aug 1;130(8):1028-1037.
http://www.ncbi.nlm.nih.gov/pubmed/22893074

1. Butler NJ, Furtado JM, Winthrop KL, Smith JR. Ocular toxoplasmosis II: clinical features, pathology and management. Clin Experiment Ophthalmol. 2012 Jun 19. doi: 10.1111/j.1442-9071.2012.02838.x. [Epub ahead of print]
Key words: Ocular Toxoplasmosis, pathology
http://www.ncbi.nlm.nih.gov/pubmed/22712598

1. Kozak I, Ahuja A, Gangaputra S, Van Natta ML, Thorne JE, Freeman WR. Optic nerve head morphology and visual field function in patients with AIDS and without infectious retinitis. Ocul Immunol Inflamm. 2012 Jun 14. [Epub ahead of print]
Key words: AIDS, optic nerve findings, visual fiend measurements, visual function
http://www.ncbi.nlm.nih.gov/pubmed/22697270

2. Sugar EA, Jabs DA, Ahuja A, Thorne JE, Danis RP, Meinert CL; Studies of the Ocular Complications of AIDS Research Group. Incidence of cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Am J Ophthalmol. 2012 Jun;153(6):1016-24.e5.
Key words: CMV retinitis, AIDS, incidence
http://www.ncbi.nlm.nih.gov/pubmed/22790073

Return to top of Publications - Ophthalmology Archives


Search Publications
 
   
July 2015 articles:
Prospective Reimbursement Analysis
Johns Hopkins Clinical Research Network
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement (between Johns Hopkins and a company receiving an NIH research award)
Giovanni Armenise - Harvard Foundation Career Development Award
Free to Breathe Accelerate Clinical Trials Grant
2016 Searle Scholars Program
Otolaryngology Head & Neck Cancer SPORE - Career Development Projects
HHMI Gates Simons Faculty Scholars Program
Damon Runyon Cancer Research Foundation Accepting Applications for Early Career Fellowship Awards
Fondation Leducq Transatlantic Networks of Excellence Program
ALS Therapy Alliance
New Biosketch Format for NIH and AHRQ Applications
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for July, August and September

       

 

JHM AppointmentsEmployment @ JHM | Finding a Doctor | Disclaimer | Maps & Directions | Contact JHM 

 

                                                                                                                                                           The Web Center