Web notes  

September 2016

Ophthalmology Archives

1. Singman E, Srikumaran D, Hackett K, Kaplan B, Jun A, Preece D, Ramulu P. Benchmarking the Wilmer general eye services clinics: baseline metrics for surgical and outpatient clinic volume in an educational environment. BMC Med Educ. 2016 Jan 27;16(1):29. doi: 10.1186/s12909-016-0556-x.

2. Singman EL, Daphalapurkar N, White H, Nguyen TD, Panghat L, Chang J, McCulley T. Indirect traumatic optic neuropathy. Mil Med Res. 2016 Jan 11;3:2. doi: 10.1186/s40779-016-0069-2. eCollection 2016. Review.

1. Pan Q, Xu Q, Boylan NJ, Lamb NW, G Emmert D, Yang JC, Tang L, Heflin T, Alwadani S, Eberhart CG, Stark WJ, Hanes J. Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats. J Control Release. 2015 Mar 10;201:32-40.
Key words: Corneal rejection; Corneal transplantation; Dexamethasone; Drug delivery; PLGA

2. Soiberman U, Pan Q, Daoud Y, Murakami P, Stark WJ. Iris suture fixation of subluxated intraocular lenses. Am J Ophthalmol. 2015 Feb;159(2):353-9. doi: 10.1016/j.ajo.2014.11.009.
Key words: intraocular lens; subluxation; iris suture fixation

3. Zigler, Jr. JS and Sinha D. ?A3/A1-crystallin: More than a lens protein. Prog Retin Eye Res. 2015 Jan; 44C: 62-85. doi: 10.1016/j.preteyeres.2014.11.002.
Key words: Astrocyte, lysosome, retinal pigment epithelial cell, signaling, bA3/A1-crystallin

1. Goldstein JE, Chun, MW, Fletcher DC, Deremeik JT, Massof RW, Low Vision Research Network Study Group. Visual ability of patients seeking outpatient services in the United States. JAMA Ophthalmol. 2014;132(10):1169-77.
Key words: low vision, outpatient, visual ability

2. Valapala M, Edwards M, Hose S, Grebe R, Bhutto IA, Cano M, Berger T, Mak TW, Wawrousek E, Handa JT, Lutty GA, Samuel Zigler J Jr, Sinha D. Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response. Aging Cell. 2014 Dec;13(6):1091-4.
Key words: Cryba1 cKO mice, inflammation, age-related macular degeneration, lipocalin-2, lysosomes

1. Cunningham ET Jr, Lowder CY, Miserocchi E, Thorne JE, Zierhut M. Sarcoid uveitis. Ocul Immunol Inflamm. 2014 Aug;22(4):253-6. doi: 10.3109/09273948.2014.941235.
Key words: sarcoidosis, uveitis, intraocular inflammation

2. Leung TG, Moradi A, Liu D, Nguyen QD, Dunn JP, Burkholder B, Butler NJ, Ostheimer T, Thorne JE.
Clinical features and incidence rate of ocular complications in punctate inner choroidopathy. Retina. 2014 Aug;34(8):1666-74.
Key words: choroidopathy, ocular complications, white spot syndromes

3. Ostheimer TA, Burkholder BM, Leung TG, Butler NJ, Dunn JP, Thorne JE. Tattoo-associated uveitis.
Am J Ophthalmol. 2014 Sep;158(3):637-43.e1.
Key words: uveitis, tattoo induration, sarcoidosis

4. Sen HN, Vitale S, Gangaputra SS, Nussenblatt RB, Liesgang TL, Levy-Clarke GA, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Kempen JH. Periocular corticosteroid injections in uveitis: effects and complications. Ophthalmology. 2014 Jul 11. pii: S0161-6420(14)00485-0.
Key words: corticosteroids, uveitis, complications, periocular injection, kenalog

1. Brown JC, Goldstein JE, Chan TL, Massof R, Ramulu P, Low Vision Research Network Study Group. Characterizing functional complaints in patients seeking outpatient low-vision services in the United States. Ophthalmology. 2014 Apr 23. pii: S0161-6420(14)00198-5.
Key words: low vision, complaints, reading

1. Moradi A, Amin RM, Thorne JE. The role of gender in juvenile idiopathic arthritis-associated uveitis.
J Ophthalmol. 2014;2014:461078.
Key words: JIA; Uveitis; Outcomes; Gender

2. Takakura A, Tessler HH, Goldstein DA, Guex-Crosier Y, Chan CC, Brown DM, Thorne JE, Wang R, Cunningham ET. Viral retinitis following intraocular or periocular corticosteroid administration: a case series and comprehensive review of the literature. Ocul Immunol Inflamm. 2014 Jun;22(3):175-82.
Key words: Retinitis; Infection; Side-effects of regional steroid use

3. Artornsombudh P, Pistilli M, Foster CS, Pujari SS, Gangaputra SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH. Factors predictive of remission of new-onset anterior uveitis. Ophthalmology. 2014 Mar;121(3):778-84. doi: 10.1016/j.ophtha.2013.09.041. Epub 2013 Dec 15.
Key words: Anterior uveitis; Remission; Treatment outcomes; Risk factors

4. Suhler EB, Lim LL, Beardsley RM, Giles TR, Pasadhika S, Lee ST, de Saint Sardos A, Butler NJ, Smith JR, Rosenbaum JT. Rituximab therapy for refractory orbital inflammation: results of a phase 1/2, dose-ranging, randomized clinical trial. JAMA Ophthalmol. 2014 Mar 20. doi: 10.1001/jamaophthalmol.2013.8179. [Epub ahead of print]
Key words: Rituximab, Orbital Inflammation, Thyroid Eye Disease, Treatment Response

1. Althoff KN, Rebeiro P, Brooks JT, Buchacz K, Gebo K, Martin J, Hogg R, Thorne JE, Klein M, Gill MJ, Sterling TR, Yehia B, Silverberg MJ, Crane H, Justice AC, Gange SJ, Moore R, Kitahata MM, Horberg MA; for the North American AIDS Cohort Collaboration on Research Design (NA-ACCORD). Disparities in the quality of HIV care when using US Department of Health and Human Services indicators. Clin Infect Dis. 2014 Feb 17. [Epub ahead of print]
Key words: Quality of care disparity; HIV care; North American AIDS Cohort Collaboration

2. Burkholder BM, Leung TG, Ostheimer TA, Butler NJ, Thorne JE, Dunn JP. Spectral domain optical coherence tomography findings in acute syphilitic posterior placoid chorioretinitis. J Ophthalmic Inflamm Infect. 2014 Jan 27;4(1):2. doi: 10.1186/1869-5760-4-2.
Key words: OCT findings, placoid chorioretinitis; syphilitic eye disease

3. Moradi A, Sepah YJ, Sadiq MA, Nasir H, Kherani S, Sophie R, Do DV, Nguyen QD. Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema.
World J Diabetes. 2013 Dec 15;4(6):303-309.
Key words: Diabetic Macular Edema, Diabetic Retinopathy, Anti Vascular endothelial growth factor agents, Aflibercept, EYLEA

4. Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler Jr JS, Sinha D. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/bA3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy. 2014; 10(3).
Key words: MTORC1, V-ATPase, autophagy, lysosomes, bA3/A1-crystallin

1. Artornsombudh P, Pistilli M, Foster CS, Pujari SS, Gangaputra SS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Kempen JH. Factors predictive of remission of new-onset anterior uveitis. Ophthalmology. 2013 Dec 14. pii: S0161-6420(13)00886-5. doi: 10.1016/j.ophtha.2013.09.041. [Epub ahead of print]
Key words: Anterior Uveitis, Treatment, Induction of Remission

2. Levin MH, Pistilli M, Daniel E, Gangaputra SS, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Kempen JH; Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study. Incidence of visual improvement in uveitis cases with visual impairment caused by macular edema. Ophthalmology. 2013 Dec 11. pii: S0161-6420(13)00843-9. doi: 10.1016/j.ophtha.2013.09.023. [Epub ahead of print]
Key words: Uveitis, Macular Edema, Visual Improvement, Epidemiology

3. Leung TG, Thorne JE. Emerging drugs for the treatment of uveitis. Expert Opin Emerg Drugs. 2013 Dec;18(4):513-21. doi: 10.1517/14728214.2013.861417.
Key words: Uveitis, Biologic Therapy, Conventional Immunosuppression

1. Weinberg RS, Burkholder BB, Srikumaran D, Lee BS. Reply to: Inadvertent trypan blue posterior capsule staining during cataract surgery. Am J Ophthalmol. 2013 Nov;156(5):1069-70.
Key words: cataract, trypan blue posterior capsule staining


2. Leung TG, Thorne JE. Emerging drugs for the treatment of uveitis. Expert Opin Emerg Drugs. 2013 Dec;18(4):513-21. doi: 10.1517/14728214.2013.861417.
Key words: uveitis, immunosuppressive drug therapy, biologics

1. Baxter SL, Pistilli M, Pujari SS, Liesegang TL, Suhler EB, Thorne JE, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Kempen JH. Risk of choroidal neovascularization among the uveitides. Am J Ophthalmol. 2013 Sep;156(3):468-77.e2. doi: 10.1016/j.ajo.2013.04.040.
Key words: Uveitis, choroidal neovascularization, risk factors, SITE Study

2. Burkholder BM, Wang J, Dunn JP, Nguyen QD, Thorne JE. Postoperative outcomes after fluocinolone acetonide implant surgery in patients with birdshot chorioretinitis and other types of posterior and panuveitis. Retina. 2013 Sep;33(8):1684-93. doi: 10.1097/IAE.0b013e31828396cf.
Key words: Birdshot chorioretinitis, fluocinolone acetonide implants, ocular hypertension, post- operative outcomes

3. Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema.
Ophthalmology. 2013 Sep;120(9):1852-9.
Key words: Fluorescin angiography, uveitic macular edema, optical coherence

4. Lucas GM, Jing Y, Sulkowski M, Abraham AG, Estrella MM, Atta MG, Fine DM, Klein MB, Silverberg MJ, Gill MJ, Moore RD, Gebo KA, Sterling TR, Butt AA; NA-ACCORD of the IeDEA. Hepatitis C viremia and the risk of chronic kidney disease in HIV-infected individuals. J Infect Dis. 2013 Oct 15;208(8):1240-9.
Key words: HIV/AIDs, Hepatitis C, Kidney Disease, Infectious Disease

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Search Publications
September 2016 articles:
Henrietta Lacks Memorial Lecture
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
JHM HSR Recertification Training
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
7th Annual Mirowski Discovery Award
Department of Defense Prostate Cancer Research Program (PCRP)
2016 Martin D. Abeloff Award for Excellence in Public Health and Cancer Control
The Sherrilyn and Ken Fisher Center for Environmental Infectious Diseases Discovery Program
2017 Arnold O. Beckman Postdoctoral Fellowship for Life Sciences Research
Progeria Research Foundation Seeks Proposals for Research on Hutchinson-Gilford Progeria Syndrome (HGPS, or Progeria)
Burroughs Wellcome Fund - Career Awards for Medical Scientists
Bright Focus Foundation Alzheimer's Disease Research Grants
Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation Grant Program
Bright Focus Foundation National Glaucoma Research Grants
Milstein Medical Asian American Partnership Foundation Fellowship and Project Awards
Michael J. Fox Foundation (MJFF) Challenge
Research Administration Training Program for Existing Staff (RPES)
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

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The JHU SOM Core Showcase
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