Web notes  

May 2016

Neuroscience Archives

1. Corbit LH, Fischbach SC, Janak PH. Nucleus accumbens core and shell are differentially involved in general and outcome-specific forms of pavlovian-instrumental transfer with alcohol and sucrose rewards. Eur J Neurosci. 2016 Mar 11. doi:10.1111/ejn.13235. [Epub ahead of print]
Key words: nucleus accumbens, alcohol, sucrose, rewards, incentive, learning, motivation, stimulus, ventral striatum

2. de Melo J, Zibetti C, Clark BS, Hwang W, Miranda-Angulo AL, Qian J, Blackshaw S. Lhx2 is an essential factor for retinal gliogenesis and notch signaling. J Neurosci. 2016 Feb 24;36(8):2391-405. doi:10.1523/JNEUROSCI.3145-15.2016.
Key words: Lhx2; retinal gliogenesis; Müller glia; Notch; differentiation; retina

3. Haith AM, Pakpoor J, Krakauer JW. Independence of movement preparation and movement initiation.
J Neurosci. 2016 Mar 9;36(10):3007-15. doi:10.1523/JNEUROSCI.3245-15.2016.
Key words: preparation, movement, initiation

4. Lagerlöf O, Slocomb JE, Hong I, Aponte Y, Blackshaw S, Hart GW, Huganir RL. The nutrient sensor OGT in PVN neurons regulates feeding. Science. 2016 Mar 18;351(6279):1293-6. Doi:10.1126/science.aad5494.
Key words: OGT, PVN, feeding

5. Long AW, Roemmich RT, Bastian A. Blocking trial-by-trial error correction does not interfere with motor learning in human walking. J Neurophysiol 2016 Feb 24:jn.00941.2015. doi:10.1152/jn.00941.2015. [Epub ahead of print]
Key words: motor learning, adaptation, feedback, gait, human walking.

6. Mo A, Luo C, David FP, Mukamel EA, Henry GL, Nery JR, Urich MA, Picard S, Lister R, Eddy SR, Beer MA, Ecker JR, Nathans J. Epigenomic landscapes of retinal rods and cones. Elife. 2016 Mar 7;5. pii:e11613. Doi:10.7554/eLife.11613.
Key words: epigenomic, retinal, rods, cones

7. Statton MA, Toliver A, Bastian AJ. A dual-learning paradigm can simultaneously train multiple characteristics of walking. J Neurophysiol 2016 Mar 9:jn.00090.2016. doi: 10.1152/jn.00090.2016. [Epub ahead of print]
Key words: dual-learning, walking

8. Vaziri S, Connor CE. Representation of gravity-aligned scene structure in ventral pathway visual cortex.
Curr Biol. 2016 Feb 23. pii: S0960-9822(16)00072-5. doi:10.1016/j.cub.2016.01.022.
Key words: gravity-aligned, visual cortex

1. Gu Y, Chiu SL, Liu B, Wu PH, Delannoy M, Lin DT, Wirtz D, Huganir RL. Differential vesicular sorting of AMPA and GABAA receptors. Proc Natl Acad Sci USA. 2016 Feb 16;113(7):E922-31. doi: 10.1073/pnas.152726113. Epub 2016 Feb 2.
Key words: vesicular, sorting, receptors

2. Kim J, Matney CJ, Roth RH, Brown SP. Synaptic organization of the neuronal circuits of the claustrum.
J Neurosci. 2016 Jan 20;36(3):773-84. doi: 10.1523/JNEUROSCI.3643-15.2016.
Key words: claustrum

3. Wang H, Ardiles AO, Yang S, Tran T, Posada-Duque R, Valdivia G, Back M, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A. Metabotropic glutmate receptors induce a form of LTP controlled by translation and arc signaling in the hippocampus. J Neurosci. 2016 Feb 3; 36(5):1723-9. doi: 10.1523/JNEUROSCI.0878-15.2016.
Key words: LTP, translation, arc

4. Zeng Y, Yao B, Shin J, Lin L, Kim N, Song Q, Liu S, Su Y, Guo JU, Huang L, Wan J, Wu H, Qian J, Cheng X, Zhu H, Ming GL, Jin P, Song H. Lin28A binds active promoters and recruits Tet1 to regulate gene expression. Mol Cell. 2016 Jan7;61(1):153-60. doi:10.1016/j.molcel.2015.11.020. Epub 2015 Dec 17.
Key words: Lin28A, gene expression

1. Campbell DP, Chrysostomou E, Doetzlhofer A. Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep. 2016 Jan 20; 6:1984. doi: 10.1038/rep19484.
Key words: notch, auditory, development

2. Guha P, Harraz MM, Snyder SH. Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade. Proc Natl Acad Sci USA. 2016 Jan 19. pii: 201524860. [Epub ahead of print]
Key words: cocaine, nitric, oxide, GAPDH

3. Harraz MM, Tyagi R, Cortés P, Snyder SH. Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic rheb degradation. Mol Psychiatry. 2016 Jan 19. doi:10.1038/mp.2015.211. [Epud ahead of print]
Key words: ketamine, mTOR, Rheb

4. Hu B, Kane-Jackson R, Niebur E. A proto-object based saliency model in three-dimensional space.
Vision Res. 2015 Dec 28. pii: S0042-6989(15)00370-3. doi: 10.1016/j.visres.2015.12.004. [Epub ahead of print]
Key words: object, saliency, space

5. Zhang-Hooks Y, Agarwal A, Mishina M, Bergles DE. NMDA receptors enhance spontaneous activity and promote neuronal survival in the developing cochlea. Neuron. 2016 Jan 6. pii: S0896-6273(15)01118-6. doi:10.1016/j.neuron.2015.12.016. [Epub ahead of print]
Key words: NMDA, receptors, activity, survival, cochlea

1. Chen X, Stuphorn V. Sequential selection of economic good and action in medial frontal cortex of macaques during value-based decisions. Elife. 2015 Nov 27;4. pii: e09418. doi: 10.7554/eLife.09418. [Epub ahead of print]
Key words: macaques, value-based decisions

2. He K, Huertas M, Hong SZ, Tie X, Hell JW, Shouval H, Kirkwood A. Distinct eligibility traces for LTP and LTD in cortical synapses. Neuron. 2015 Nov 4;88(3):528-38. doi: 10.1016/j.neuron.2015.09.037.
Key words: eligibility, traces, LTP, LTD

3. Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A. Brief dark exposure reduces tonic inhibition in visual cortex. J Neurosci. 2015 Dec 2;35(48):15916-20. doi:10.1523/JNEUROSCI.1813-15.2015.
Key words: dark, exposure, visual, cortex

4. Therrien AS, Wolpert DM, Bastian AJ. Effective reinforcement learning following cerebellar damage requires a balance between exploration and motor noise. Brain. 2015 Dec 1. pii: awv329. [Epub ahead of print]
Key words: learning, cerebellar damage

5. Wang HC, Lin CC, Cheung R, Zhang-Hooks Y, Agarwal A, Ellis-Davies G, Rock J, Bergles DE. Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells.
Cell. 2015 Dec 3;163(6):1348-59. doi: 10.1016/j.cell.2015.10.070. Epub 2015 Nov 25.
Key words: spontaneous, activity, cochlear, support cells

6. Yang H, Kwon SE, Severson KS, O'Connor DH. Origins of choice-related activity in mouse somatosensory cortex. Nat Neurosci. 2015 Dec 7. doi: 10.1038/nn.4183. [Epub ahead of print]
Key words: choice, somatosensory, cortex

1. Silva D, Feng T, Foster DJ. Trajectory events across hippocampal place cells require previous experience.
Nat Neurosci. 2015 Oct 26. doi:10.1038/nn.4151. [Epub ahead of print]
Key words: trajectory, hippocampal place, experience

2. Statton MA, Encarnacion M, Celnik P, Bastian AJ. A Single bout of moderate aerobic exercise improves motor skill acquisition. PLoS One. 2015 Oct 27;10(10):e0141393. doi: 10.1371/journal.pone.014393. eCollection 2015.
Key words: aerobic exercise, motor skill acquisition

1. Hussain NK, Thomas GM, Luo J, Huganir RL. Regulation of AMPA receptor subunit GluA1 surface expression by PAK3 phosphorylation. Proc Natl Acad Sci USA. 2015 Oct 12. pii: 201518382. [Epub ahead of print]
Key words: AMPA, receptor, PAK3, phosphorylation

2. Lin CC, Prokop-Prigge KA, Preti G, Potter CJ. Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions. Elife. 2015 Sep 30;4. doi: 10.7554/eLife.08688. [Epub ahead of print]
Key words: odors, drosophila, female oviposition

3. Lin CC, Potter CJ. Re-classification of Drosophila melanogaster trichoid and intermediate sensilla using fluorescence-guided single sensillum recording. PLoS One. 2015 Oct 2;10(10):e0139675. doi: 10.1371/journal.pone.0139675. eCollection 2015.
Key words: drosophila, trichoid, sensilla

4. Vazquez A, Statton MA, Busgang SA, Bastian AJ. Split-belt walking adaptation recalibrates sensorimotor estimates of leg speed, but not position or force. J Neurophysiol. 2015 Sep 30;jn.00302.2015. doi: 10.1152/jn.00302.2015. [Epub ahead of print]
Key words: split-belt walking, sensorimotor

1. Larson VA, Zhang Y, Bergles DE. Electrophysiological properties of NG2+ Cells: matching physiological studies with gene expression profiles. Brain Res. 2015 Sep 15. pii: S0006-8993(15)00708-8. doi: 10.1016/j.brainres.2015.09.010. [Epub ahead of print]
Key words: NG2+ cells, expression profiles

2. Lee H, Wang C, Deshmukh SS, Knierim JJ. Neural population evidence of functional heterogeneity along the CA3 transverse axis: pattern completion versus pattern separation. Neuron. 2015 Sep 2;87(5):1093-105. doi: 10.1016/j.neuron.2015.07.012. Epub 2015 Aug 19.
Key words: neural population, CA3, transverse axis

3. Zhang L, von der Heydt R. Visual selectivity and top-down modulation of neurons in monkey V2 during free viewing. J Vis. 2015 Sep 1;15(12):1245. doi: 10.1167/15.12.1245.
Key words: visual selectivity, V2

1. Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder S. Huntington's disease: neural dysfunction linked to inositol polyphosphate multikinase. Proc Natl Acad Sci USA. 2015 Aug 4; 112(31):9751-6. doi: 10.1073/pnas.1511810112. Epub 2015 Jul 20.
Key words: Huntington's, polyphosphate multikinase

2. Fu C, Xu J, Li RJ, Crawford JA, Khan AB, Ma TM, Cha JY, Snowman AM, Pletnikov MV, Snyder SH. Inositol hexakisphosphate kinase-3 regulates the morphology and synapse formation of cerebellar purkinje cells via spectrin/adducin. J Neurosci. 2015 Aug 5:35(31):11056-67. doi: 10.1523/JNEUROSCI.1069-15.2015.
Key words: hexakisphosphate kinase-3, cerebellar, spectrin

3. Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. Defective age-dependent metaplasticity in a mouse model of Alzheimer's disease. J Neurosci. 2015 Aug 12;35(32):11346-57. doi: 1523/JNEUROSCI.5289-14.2015.
Key words: metaplasticity, alzheimer's disease

4. Mills EA, Davis CO, Bushong EA, Boassa D, Kim KY, Ellisman MH4 Marsh-Armstrong N. Astrocytes phagocytose focal dystrophies from shortening myelin segments in the optic nerve of Xenopus laevis at metamorphosis. Proc Natl Acad Sci USA. 2015 Aug 3. pii: 201506486. [Epub ahead of print].
Key words: astrocytes, dystrophies, Xenopus

5. Tan HL1, Queenan BN1, Huganir RL2. GRIP1 is required for homeostatic regulations of AMPAR trafficking. Proc Natl Acad Sci USA. 2015 Aug 11;112(32):11026-31. doi: 10.1073/pnas.1512786112. Epub 2015 Jul 27.
Key words: GRIP1, homeostatic, AMPAR

1. Golden EJ, Benito-Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci USA. 2015 Jul 21;112(29):E3864-73.
Key words: RNA-binding, LIN28B, cochlea

2. Hand RA, Khalid S, Tam E, Kolodkin AL. Axon dynamics during neocortical laminar innervation.
Cell Rep. 2015 Jul 14;12(2):172-82. doi: 10.1016/j.celrep.2015.06.026.
Key words: axon, neocortical, laminar

3. Pfeiffer BE, Foster DJ. PLACE CELLS. Autoassociative dynamics in the generation of sequences of hippocampal place cells. Science. 2015 Jul 10;349(6244):180-3. doi:10.1126/science.aaa9633.
Key words: place cells, hippocampal

1. Harraz MM, Snyder SH1. Nitric oxide-GAPDH transcriptional signaling mediates behavioral actions of cocaine. CNS Neurol Disord Drug Targets. 2015 May 29. [Epub ahead of print].
Key words: nitric oxide, cocaine

2. Petrus E, Rodriguez G, Patterson R, Connor B, Kanold PO, Lee HK. Vision loss shifts the balance of feedforward and intracortical circuits in opposite directions in mouse primary auditory and visual cortices. J Neurosci. 2015 Jun 10;35(3)8790-801. doi: 10.1523/JNEUROSCI.4975-14.2015.
Key words: vision loss, intracortical, mouse

1. Martin AB1, von der Heydt R2. Spike Synchrony Reveals Emergence of Proto-objects in Visual Cortex.
J Neurosci. 2015 Apr 29;35(17):6860-70. doi:10.1523/JNEUROSCI.3590-14.2015.
Key words: spike synchrony, cortex

2. Sun LO1, Brady CM1, Cahill H2, Al-Khindi T1, Sakuta H3, Dhande OS4, Noda M3, Huberman AD4, Nathans J2, Kolodkin AL5. Functional Assembly of Accessory Optic System Circuitry Critical for Compensatory Eye Movements.
Neuron. 2015 May 6. pii: S0896-6273(15)00288-3. doi: 10.1016/j.neuron.2015.03.064. [Epub ahead of print]
Key words: accessory optic system, eye movements

3. Toda AM1, Huganir RL2. Regulation of AMPA Receptor Phosphorylation by the Neuropeptide PACAP38.
Proc Natl Acad Sci USA. 2015 May 11. pii: 201507229. [Epub ahead of print]
Key words: AMPA, phyosphorylation, PACAP38

4. Yan Y1, Wladyka C1, Fujii J2, Sockanathan S1.. Prdx4 is a Compartment-specific H202 Sensor that Regulates Neurogenesis by Controlling Surface Expression of GDE2.
Nat Commun. 2015 May 6;6:7006. doi: 10.1038/ncomms8006.
Key words: Prdx4, H202, GDE2

1. Long AW, Finley JM, Bastian AJ. A marching-walking hybrid induces step length adaptation and transfers to natural walking. J Neurophysiol 2015 Apr 1;jn.00779.2014. doi: 10.1152/jn.00779.2014. [Epub ahead of print]
Key words: marching-walking, natural walking

2. Roemmich RT, Bastian AJ. Two ways to save a newly learned motor pattern. J Neurophysiol 2015 Apr 8;jn.00965.2014. doi: 10.1152/jn.00965.2014. [Epub ahead of print]
Key words: learned motor pattern

3. Zhang W, Wu J, Ward MD, Yang S, Chuang YA, Xiao M, Li R, Leahy DJ, Worley PF. Structural basis of arc binding to synaptic proteins: implications for cognitive disease. Neuron2015 Apr 8. pii:S0896-6273(15)00254-8. doi: 10.1016/j.neuron.2015.03.030. [Epub ahead of print]
Key words: arc, cognitive disease


1. Paul BD, Snyder SH. Protein sulfydration. Methods Enzymol.2015;555:79-90. doi: 10.1016/bs.mie.2014.11.021.
Key words: protein sulfhydration

2. Riabinina O, Luginbuhl D, Marr E, Liu S, Wu MN, Luo L, Potter CJ. Improved and expanded Q-system reagents for genetic manipulations. Nat Methods.2015 Mar;12(3):219-22. doi: 10.1038/nmeth.3250.
Key words: Q-system reagents, genetic manipulations, protein engineering, transgenic regulation

1. Rao F, Xu J, Fu C, Cha JY, Gadalla MM, Xu R, Barrow JC, Snyder SH. Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. Proc Natl Acad Sci USA. 2015 Feb 10;112(6);1773-8. doi:10.1073/pnas.1424642112.
Key words: inositol, pyrophosphates, metastasis

2. Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X. Tmem100 Is a regulator of TRPA1-TRPV1 complex and contributes to persistent pain. Neuron. 2015 Jan 28.pii: S0896-6273(14)01174-X. doi: 10.1016/j.neuron.2014.12.065.
Key words: Tmem100, persistent pain

3. Zhang Y, Cudmore RH, Lin DT, Linden DJ, Huganir RL. Visualization of NMDA receptor-dependent AMPA receptor synaptic plasticity in vivo. Nat Neurosci. 2015 Mar;18(3):402-7.
Key words: visualization, NMDA, plasticity

1. Araki Y, Zeng M, Zhang M, Huganir RL. Rapid dspersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP. Neuron. 2015 Jan 7;85(1):173-89.
Key words: SynGAP, spines, AMPA, receptor, LTP

2. McNeil BD, Pundir P, Meeker S, Han L, Undem BJ, Kulka M, Dong X. Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. Nature 2014 Dec 17. doi:10.1038/nature14022. [Epub ahead of print].
Key words: mast, cell, receptor, allergic, drug, reactions

3. Riabinina O, Luginbuhl D, Marr E, Liu S, Wu MN, Luo L, Potter CJ. Improved and expanded Q-system reagents for genetic manipulations. Nat Methods 2015 Jan 12. doi:10.1038/nmeth.3250. [Epub ahead of print].
Key words: Q-system, genetic manipulations

4. M, Yoo S, Newman EA, Wang H, Bedont JL, de Melo J, Miranda-Angulo AL , Gil-Perotin S, Garcia- Salvatierra J, Lee DA, Zibetti C, Duran-Moreno Verdugo JM, Blackshaw S. The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. J Neurosci. 2014 Dec 10:34(50):16809-20. doi: 10.1523/JNEUROSCI.1711-14.2014.
Key words: Lhx2, Tanycyte, differentiation

1. Diering GH, Gustina AS, Huganir RL. PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity.
Neuron. 2014 Nov 19;84(4):790-805.
Key words: PKA-GluA1, homeostatic, plasticity

2. Gomez-Ramirez M, Trzcinski NK, Mihalas S, Niebur E, Hsiao SS. Temporal correlation mechanisms and their role in feature selection: a single-unit study in primate somatosensory cortex.
PLoS Biol2014 Nov 25;12(11):e1002004.
Key words: temporal correlation, primate somatosensory

1. Rao F, Xu J, Khan AB, Gadalla MM, Cha JY, Xu R, Tyagi R, Dang Y, Chakraborty A, Snyder SH. Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death. Proc Natl Acad Sci USA. 2014 Nov 11;111(45):16005-10. doi:10.1073/pnas.14179000111.
Key words: CRL4, DNA repair, cell death

2. Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH. serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-d-aspartate-?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk. J Biol Chem. 2014 Oct 24:289(43):29631-41. Doi:10.1074/jbcc.M114.571604.
Key words: serine racemase, stargazin, PSD-95, neurotransmission

1. Benito-Gonzalez A1, Doetzlhofer A2. Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of hedgehog signaling. J Neurosci. 2014 Sep 17;34(38):12865-76.
Key words: auditory, hair cell, hedgehog

2. Keller JL1, Bastian AJ2. A home balance exercise program improves walking in people with cerebellar ataxia. Neurorehabil Neural Repair. 2014 Oct:28(8):770-8.
Key words: balance, cerebellar, ataxia

3. Ramenahalli S1, Mihalas S2, Niebur E3. Local spectral anisotropy is a valid cue for figure-ground organization in natural scenes. Vision Res. 2014 Oct;103:116-26.
Key words: spectral, anisotropy, natural, scenes

4. Vaziri S1, Carlson ET1, Wang Z2, Connor CE3. A channel for 3D environmental shape in anterior inferotemporal cortex. Neuron. 2014 Oct 1;84(1):55-62.
Key words: 3D, shape, inferotemporal, cortex

5. Wang HC1, Bergles DE. Spontaneous activity in the developing auditory system. Cell Tissue Res. 2014 Oct 9. [Epub ahead of print].
Key words: activity, auditory

6. Wang SH1, Celic I1, Choi SY2, Riccomagno M1, Wang Q1, Sun LO1, Mitchell SP1, Vasiokhin V3, Huganir RL1, Kolodkin AL4. Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J Neurosci. 2014 Sep 17;34(38):12745-61.
Key words: Dlg5, dendritic, spine, cadherin

1. Ramenahalli S, Mihalas S, Niebur E. Local spectral anisotropy is a valid cue for figure-ground organization in natural scenes. Vison Res. 2014 Aug 29. pii:S0042-6989(14)00191-6. doi:10.1016/j.visres.2014.08.012. [Epub ahead of print]
Key words: spectral, anisotropy, figure-ground, organization

1. Gao M, Maynard KR, Chokshi V, Song L, Jacobs C, Wang H, Tran T, Martinowich K, Lee HK. Rebound potentiation of inhibition in juvenile visual cortex requires vision-induced BDNF expression.
J Neurosci. 2014 Aug 6;34(32):10770-9. doi:10.1523/JNEUROSCI.5454-13.2014.
Key words: visual cortex, BDNF

2. Hussain NK, Diering GH, Sole J, Anggono V, Huganir RL. Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARS.
Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11840-5. doi:10.1073/pnas.1412415111. Epub 2014 Jul 28.
Key words: Nexin 27, trafficking, AMPARs

3. Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH. Serine racemase regulated by binding to stargazin and PSD-95: potential NMDA-AMPA glutamate neurotransmission cross-talk.
J Biol Chem., 2014 Aug 27. pii:jbc.M114.571604. [Epub ahead of print].

1. David CH, Kim KY,Bushong EA, Mills EA, Boassa D,Shih T, Kinebuchi M, Phan S, Zhou Y, Bihlmeyer NA, Nguyen JV, Jin Y, Ellisman MH, Marsh-Armstrong N. Transcellular degradation of axonal mitochondria.
Proc Natl Acad Sci USA. 2014 Jul 1;111(26):9633-8. doi: 10.1073/pnas.1404651111.
Key words: degradation, mitochondria

2. Kim J, Matney CJ, Blankenship A, Hestrin S, Brown SP. Layer 6 corticothalamic neurons activate a cortical output layer, layer 5a. J Neurosci. 2014 Jul 16;34(29):9656-64. doi:10.1523/JNEUROSCI.1325-14.2014.
Key words: cortical output, layer 5a

3. Lee DA, You S, Pak T, Salvatierra J, Velarde E, Aja S, Blackshaw S. Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice. Front Neurosci. 2014 Jun13;8:157. doi: 10.3389/fnins.2014.00157.
Key words: hypothalamic neurogenesis

4. Paukert M, Agarwal A, Cha J, Doze VA, Kang JU, Bergles DE. Norepinephrine controls astroglial responsiveness to local circuit activity. Neuron. 2014 Jun 18;82(6):1263-70. doi:10.1016/j.neuron.2014.04.038.
Key words: norepinephrine, circuit activity

1. Bai Y, Lathia JD, Zhang P, Flavahan W, Rich JN, Mattson MP. Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells. Glia. 2014 Jun 7. doi: 10.1002/glia.22708.
Key words: TRF2, glioblastoma

2. Baxi EG, Schott JT, Fairchild AN, Kirby LA, Karani R, Uapinyoying P, Pardo-Villamizar C, Rothstein JR, Bergles DE, Calabresi PA. A selective thyroid hormone ? receptor agonist enhances human and rodent oligodendrocyte differentiation. Glia. 2014 May 24. doi:10.1002/glia.22697.
Key words: thyroid hormone, oligodendrocyte

3. Huang S, Rozas C, Treviño M, Contreras J, Yang S, Song L, Yoshioka T, Lee HK, Kirkwood A. Associative hebbian synaptic plasticity in primate visual cortex. J Neurosci. 2014 May 28;34(22):7575-9. doi:10.1523/JNEUROSCI.0983-14.2014.
Key words: synaptic plasticity, primate visual cortex

4. Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, Tang Z, Han L, Chu YX, Wang Y, Hin N, Tsukamoto T, Slusher B, Guan X, Wei F, Raja SN, Dong X, Guan Y. Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice. Pain. 2014 May 9. pii:S0304-3959(14)00228-0. doi: 10.1016/j.pain.2014.05.008.
Key words: MrgC receptor, sensory neurons

5. Monaco JD, Rao G, Roth ED, Knierim JJ. Attentive scanning behavior drives one-trial potentiation of hippocampal place fields.
Nat Neurosci. 2014 May;17(5):725-31. doi: 10.1038/nn.3687.
Key words: hippocampal place fields

6. Zhong X, Gutierrez C, Xue T, Hampton C, Vergara MN, Cao LH, Peters A, Park TS, Zambidis ET, Meyer JS, Gamm DM, Yau KW, Canto-Soler MV. Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047. doi:10.1038/ncomms5047.
Key words: three-dimensional retinal tissue, iPSCs

1. Bedont JL, Legates TA, Slat EA, Byerly MS, Wang H, Hu J, Rupp AC, Qian J, Wong GW, Herzog ED, Hattar S, Blackshaw S. Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus. Cell Rep. 2014 Apr 23. pii:S2211-1247(14)00257-5.
Key words: Lhx1, circadian function, suprachiasmatic

2. Bhanpuri NH, Okamura AM, Bastian AJ. Predicting and correcting ataxia using a model of cerebellar function. Brain. 2014 May 8. [Epub ahead of print]
Key words: ataxia, cerebellar function

3. Gwilliam JC, Yoshioka T, Okamura AM, Hsiao SS. Neural coding of lump detection in compliant artificial tissue. J Neurophysiol. 2014 May 7. [Epub ahead of print]
Key words: neural coding, compliant artificial tissue

4. Wan R, Weigand LA, Bateman R, Griffioen K, Mendelowitz D, Mattson MP. Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability.
J Neurochem. 2014 May;129(4):573-80. [Epub 2014 Feb 10]
Key words: BDNF, heart rate, parasympathetic

5. Wu X, Foster DJ. Hippocampal replay captures the unique topological structure of a novel environment.
J Neurosci. 2014 May 7;34(19):6459-69.
Key words: hippocampal replay, novel environment

1. Cao LH, Luo DG, Yau KW. Light responses of primate and other mammalian cones. Proc Natl Acad Sci USA 2014 Feb 18; 111(7):2752-7.
Key words: primate, mammalian, cones

2. Keller JL, Bastian AJ. A home balance exercise program improves walking in people with cerebellar ataxia. Neurorehabil Neural Repair. 2014 Feb 13. [Epub ahead of print]
Key words: home balance exercise, cerebellar ataxia

3. Riccomagno MM, Sun LO, Brady CM, Alexandropoulos K, Seo S, Kurokawa M, Kolodkin AL. Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling.
Neuron. 2014 Feb 19;81(4):779-86.
Key words: Cas, retinal ganglion cell, integrin

1. Choi J, Park S, Sockanathan S. Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons. Development. 2014 Mar;141(5):1151-60.
Key words: receptors, migration, fate, cortical neurons

2. Degano AL, Park MJ, Penati J, Li Q, Ronnett GV. MeCP2 is required for activity-dependent refinement of olfactory circuits. Mol Cell Neurosci. 2014 Jan 25;59C:63-75.
Key words: MeCP2, olfactory circuits

3. Kim YS, Chu Y, Han L, Li M, Li Z, Lavinka PC, Sun S, Tang Z, Park K, Caterina MJ, Ren K, Dubner R, Wei F, Dong X. Central terminal sensitization of TRPV1 by descending serontonergic facilitation modulates chronic pain. Neuron. 2014 Jan 21. [Epub ahead of print]
Key words: TRPV1, serotonergic, pain

4. Neunuebel JP, Knierim JJ. CA3 retrieves coherent representations from degraded input: direct evidence for CA3 pattern completion and dentate gyrus pattern separation. Neuron. 2014 Jan 22; 81(2):416-27.
Key words: CA3, dentate gyrus pattern separation

1. Finley JM, Satton MA, Bastian AJ. A novel optic flow pattern speeds split-belt locomotor adaptation. J Neurophysiol 2013 Dec 11. [Epub ahead of print]
Key words: locomotor adaptation

1. Byerly MS, Swanson RD, Wong GW, Blackshaw S. Stage-specific inhibition of TrkB activity leads to long-lasting and sexually dimorphic effects on body weight and hypothalamic gene expression.
PLoS One, 2013 Nov 29;8(11):e80781
Key words: TrkB, body weight, hypothalamic


2. Chak K, Kolodkin AL. Function of the Drosophila receptor guanylyl cyclase Gyc76C in PlexA-mediated motor axon guidance. Development. 2014 Jan;141(1):136-47.
Key words: guanylyl , cyclase, PlexA, guidance

3. Lee DA, Salvatierra J, Velarde E, Wong J, Ford EC, Blackshaw S. Functional interrogation of adult hypothalamic neurogenesis with focal radiological inhibition.
J Vis Exp. 2013 Nov 14;(81)
Key words: functional, hypothalamic, radiological inhibition

4. Malone LA, Bastian AJ. Spatial and temporal asymmetries in gait predict split-belt adaptation behavior in stroke. Neuroreabil Neural Repair 2013 Nov 15. [Epub ahead of print]
Key words: gait, split-belt, stroke

5. Mealer RG, Murray AJ, Shahani N, Subramaniam S, Snyder SH. Rhes, a striatal-selective protein implicated in Huntington disease, binds Beclin-1 and activates autophagy.
J Biol Chem. 2013 Dec 9. [Epub ahead of print]
Key words: Huntington disease, Beclin-1, autophagy

6. Ramamurthy S, Chang E, Cao Y, Zhu J, Ronnett GV. AMPK activation regulates neuronal structure in developing hippocampal neurons. Neuroscience 2013 Nov 29. pii:S0306-4522(13)00995-0
Key words: AMPK, Hippocampal

7. Sharma K, Choi SY, Zhang Y, Nieland TJ, Long S, Li M, Huganir RL. High-throughput genetic screen for synaptogenic factors: identification of LRP6 as critical for excitatory synapse development.
Cell Rep 2013 Dec 3. pii:S2211-1247(13)00657-8.
Key words: synaptogenic factors, LRP6

1. Argüelles S, Camandola S, Cutler RG, Ayala A, Mattson MP. Elongation factor 2 diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions.
Free Radic Biol Med. 2013 Oct 17;67C:131-138.
Key words: elongation factor, oxidative, stress

2. Donnelly CJ, Zhang PW, Pham JT, Heusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, Rigo F, Bennett CF, Blackshaw S, Sattler R, Rothstein JD. RNA toxicity from the ASL/FTD C9ORF72 expansion is mitigated by antisense intervention.
Neuron. 2013 Oct 16; 80(2):415-28.
Key words: RNA, toxicity, ALS/FTD, Atisense

3. Sia GM, Clem RL, Huganir RL. The human language-associated gene SRPX2 regulates synapse formation and vocalization in mice. Science. 2013 Nov 22;342(6161):987-91.
Key words: language, SRPX2, synapse

4. Sun LO, Jiang Z, Rivlin-Etzion M, Hand R, Brady CM, Matsuoka RL, Yau KW, Feller MB, Kolodkin AL. On and off retinal circuit assembly by divergent molecular mechanisms. Science. 2013 Nov 1; 342(6158):1241974.
Key words: retinal circuit, assembly

5. Takahashi YK, Chang CY, Lucantonio F, Haney RZ, Berg BA, Yau HJ, Bonci A, Schoenbaum G. Neural estimates of imagined outcomes in the orbitofrontal cortex drive behavior and learning.
Neuron. 2013 Oct 16; 80(2):507-18.
Key words: imagined outcomes, behavior, learning

1. Byerly MS, Swanson RD, Wong GW, Blackshaw S. Estrogen-related receptor beta deficiency alters body composition and response to restraint stress. BMC Physiol 2013 Sep 22; 13(1):10. [Epub ahead of print]
Key words: estrogen, stress

2. Thomas GM, Hayashi T, Huganir RL, Linden DL. DHHC8-Dependent PICK1 palmitoylation is required for induction of cerebellar long-term synaptic depression. J Neurosci. 2013 Sep 25; 33(39):15401-7
Key words: PICK1, palmitoylation, depression

3. Xu R, Paul BD, Smith DR, Tyagi R, Rao F, Khan AB, Blech DJ, Vandiver MS, Harraz MM, Guha P, Ahmed I, Sen N, Gallagher M, Snyder SH. Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction. Proc Natl Acad Sci USA. 2013 Oct 1;110(40):15181-6
Key words: Inositol, multikinase, immediate early gene

4. Yang JL, Lin YT, Chuang PC, Bohr VA, Mattson MP. BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1. Neuromolecular Med. 2013 Oct 10 [Epub ahead of print]
Key words: BDNF, Apurninic/Apyrimidinic

1. Bhanpuri NH, Okamura AM, Bastian AJ. Predictive modeling by the cerebellum improves proprioception.
J Neurosci. 2013 Sep 4; 33(36):14301-6
Key words: cerebellum, proprioception

2. Korrapati S, Roux I, Glowatzki E, Doetezlhofer A. Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea. PLoS One. 2013 Aug 30; 8(8):e73276.
Key words: notch signaling, cochlea

3. Sbodio JI, Paul BD, Machamer CE, Snyder SH. Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington's Disease. Cell Rep. 2013 Sep 4. [Epub ahead of print]
Key words: Neurotoxicity, Huntingon's disease

1. Anggono V, Koç-Schmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY, Linden DJ, Plomann M, Huganir RL. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. Proc Natl Acad Sci USA. 2013 Aug 5 [Epub ahead of print].
Key words: PICK1, AMPA receptor, cerebellar long-term depression

2. Babcock JJ, Du F, Xu K, Wheelan SJ, Li M. Integrated analysis of drug-induced gene expression profiles predicts novel HERG inhibitors. PLoS One. 2013 Jul 23; 8(7):e69513.
Key words: HERG inhibitors

3. Huang S, Huganir RL, Kirkwood A. Adrenergic gating of hebbian spike-timing-dependent plasticity in cortical interneurons. J Neurosci. 2013 Aug 7; 33(32):13171-8.
Key words: Adrenergic gating, cortical interneurons

4. Miranda-Angulo AL, Byerly MS, Mesa J, Wang H, Blackshaw S. Rax regulates hypothalamic tanycyte differentiation and barrier function in mice. J Comp Neurol. 2013 Aug 12 [Epub ahead of print]
Key words: Rax, hypothalamic, tanycyte

5. Park JM, Hu JH, Milshteyn A, Zhang PW, Moore CG, Park S, Datko MC, Domingo RD, Reyes CM, Wang XJ, Etzkorn FA, Xiao B, Szumlinski KK, Kern D, Linden DJ, Worley PF. A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization. Cell. 2013 Aug 1;154(3):637-50.
Key words: prolyl-isomerase, dopamine-dependent plasticity

6. Wang Y, Mattson MP. L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner. Neurobiol Aging. 2013 Aug 7.
Key words: L-type Ca2+, CA1, 3xTgAD, age-dependent manner

7. Yang S, Megill A, Ardiles AO, Ransom S, Tran T, Koh MT, Lee HK, Gallagher M, Kirkwood A. Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats.
J Neurosci 2013 July31; 33(31):12670-8.
Key words: mGluR-LTD, Associative/Commissural, CA3, Aging

1. Rothman SM, Herdener N, Frankola KA, Mughal MR, Mattson MP. Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical A? and pTau in the mouse model of Alzheimer's Disease. Brain Res. 2013 Jul 12. [Epub ahead of print]
Key words: sleep restriction, memory impairments, Alzheimer's Disease

2. Sparta DR, Hopf FW, Gibb SL, Cho SL, Stuber GD, Messing RO, Ron D, Bonci A. Binge ethanol-drinking potentiates corticotropin releasing factor R1 receptor activity in the ventral tegmental area. Alcohol Clin Exp Res. 2013 Jun 13 [Epub ahead of print]
Key words: binge ethonal-drinking, ventral tegmental area

3. Yau JM, Connor CE, Hsiao SS. Representation of tactile curvature in macaque somatosensory area 2.
J Neurophysiol 2013 Jun;109(12):2999-3012
Key words: tactile curvature, macaque

1. Neunuebel JP, Yoganarasimha D, Rao G, Knierim JJ. Conflicts between local and global spatial frameworks dissociate neural representations of the lateral and medial entorhinal cortex.
J Neurosci. 2013 May 29; 33(22):9246-58.
Key words: spatial frameworks, entorhinal cortex

2. Xu R, Serritella AV, Sen T, Farook JM, Sedlak TW, Baraban J, Snyder SH, Sen N. Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling. Neuron. 2013 May 22; 78(4):623-30.
Key words: cocaine, Oxide-GAPDH

1. Do MT, Yau KW. Adaptation to steady light by intrinsically photosensitive retinal ganglion cells.
Proc Natl Acad Sci. U S A 2013 Apr 30:110(18):7470-5. Epub 2013 Apr 15
Key words: adaptation, photosensitive, retinal, ganglion

2. Gibo TL, Criscimagna-Hemminger SE, Okamura AM , Bastian AJ. Cerebellar motor learning: Are environment dynamics more important than error size?
J Neurophysiol. 2013 Apr 17. [Epub ahead of print]
Key words: cerebellar, motor learning

3. Hughes EG, Kang SH, Fukaya M, Bergles DE. Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain.
Nat Neurosci. 2013 Apr 28. [Epub ahead of print]
Key words: oligodendrocyte progenitors, homeostasis

4. Hutchinson ER, Kawamoto EM, Taub DD, Lal A, Abdelmohsen K, Zhang Y, Wood WH 3rd, Lehrmann E, Camandola S, Becker KG, Gorospe M, Mattson MP. Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes.
Glia. 2013 May 7. [Epub ahead of print]
Key words: neuroinflammatory responses, astrocytes

5. Kempadoo KA, Touirino C, Cho SL, Magnani F, Leinninger GM, Stuber GD, Zhang F, Myers MG, Deisseroth K, de Lecea L, Bonci A. Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA. J Neurosci. 2013 May 1;33(18):7618-7626
Key words: hypothalamic neurotensin, VTA

6. Pfeiffer B, Foster DJ. Hippocampal place-cell sequences depict future paths to remembered goals.
Nature. 2013 May 2;497(7447):74-9. Epub 2013 Apr 17.
Key words: hippocampal, place-cell, future, goals

7. Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M. Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels. Proc Natl Acad Sci U S A. 2013 May 7. [Epub ahead of print]
Key words: KCNQ, potassium, channels

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