Web notes  

April 2017

Neuroscience Archives

1. Agarwal A, Wu PH, Hughes EG, Fukaya M, Tischfield MA, Langseth AJ, Wirtz D, Bergles DE. Transient opening of the mitochondrial permeability transition pore induces microdomain calcium transients in astrocyte processes. Neuron. 2017 Feb 8;93(3):587-605.e7.
Key words: calcium transients, astrocyte

2. Amen AM, Ruiz-Garzon CR, Shi J, Subramanian M, Pham DL, Meffert MK. A rapid induction mechanism for Lin28a in trophic responses. Mol Cell. 2017 Feb 2;65(3):490-503.e7.
Key words: rapid, induction, Lin28a, trophic

3. Cave C, Park S, Rodriguez M, Nakamura M, Hoke A, Pletnikov M, Sockanathan S. GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord. Mol Neurodegener. 2017 Jan 19;12(1):8. doi: 10.1186/s13024-017-0148-1.
Key words: GDE2, neuronal survival, spinal, cord

4. Chang H, Smallwood PM, Williams J, Nathans J. Intramembrane proteolysis of astrotactins.
J Biol Chem. 2017 Jan 18. pii: jbc.M166.768077. doi: 10.1074/jbc.M116.768077. [Epub ahead of print]
Key words: intramembrane, proteolysis, astrotactins

5. Diering GH, Nirujogi RS, Roth RH, Worley PF, Pandey A, Huganir RL. Homer1a drives homeostatic scaling-down of excitatory synapses during sleep. Science. 2017 Feb 3;355(6324):511-515. doi: 10.1126/science.aai8355. Epub 2017 Feb 2.
Key words: Homer1a, homeostatic, sleep

6. Fu C, Xu J, Cheng W, Rojas T, Chin AC, Snowman AM, Arraz MM, Snyder SH. Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via ?-actinin and focal adhesion kinase.
Proc Natl Acad Sci U S A. 2017 Feb 2. pii: 201700165. doi: 10.1073/pnas.1700165114. [Epub ahead of print].
Key words: neuronal, migration, hexakisphosphate kinase 1

7. Lagerlöf O, Hart GW, Huganir RL. O-GlcNAc transferase regulates excitatory synapse maturity.
Proc Natl Acad Sci U S A. 2017 Jan 31. pii: 201621367. doi: 10.1073/pnas.1621367114.
Key words: O-GlcNAc transferase, synapse

8. Yue WW, Frederiksen R, Ren X, Luo D, Yamashita T, Shichida Y, Cornwall MC, Yau KW. Spontaneous activation of visual pigments in relation to openness/closedness of chromophore-binding pocket.
Elife. 2017 Feb 10;6. pii: e18492. doi: 10.7554/eLife.18492.
Key words: spontaneous, activation, visual pigments

1. Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S Blackshaw S. An LHX1-regulated transcriptional network controls sleep/wake coupling and thermal resistance of the central circadian clockworks. Curr Biol. 2017 Jan 9;27(1):128-136. doi: 10.1016/j.cub.2016.11.008. Epub 2016 Dec 22.
Key words: transcriptional network, central circadian clockworks

2. Chhabra A, Carrino JA, Farahani SJ, Thawait GK, Sumner CJ, Wadhwa V, Chaudhary V, Lloyd TE. Whole-body MR neurography: prospective feasibility study in polyneuropathy and Charcot-Marie-Tooth disease. J Magn Reson Imaging. 2016 Dec;44(6):1513-1521. doi:10.1002/jmri.25293. Epub 2016 Apr 29.
Key words: neurography, polyneuropathy, Charcot-Marie-tooth

3. Miller SJ, Zhang PW, Glatzer J, Rothstein JD. Astrogial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model. J Neurogenet. 2016 Dec 25;1-12. doi: 10.1080/01677063.2016.1260128. [Epub ahead of print].
Key words: astroglial transcriptome, ALS, SOD1

4. Savelli F, Luck JD, Knierim JJ. Framing of grid cells within and beyond navigation boundaries. Elife. 2017 Jan 13;6. pii:e21354. doi:10.7554/eLife.21354. [Epub ahead of print].
Key words: grid cells, navigation

5. Williford JR, von der Heydt R. Figure-ground organization in visual cortex for natural scenes.
eNeuro. 2016 Dec 29;3(6). pii: ENEURO.0127-16.2016. doi: 10.1523/ENEURO.0127-16.2016.
Key words: figure-ground organization, visual cortex

1 Corbit LH, Janak PH. Changes in the influence of alcohol-paired stimuli on alcohol seeking across extended training. Front Psychiatry, 2016 Oct 10;7:169. eCollection 2016.
Key words: Pavlovian-instrumental transfer; ethanol; habit learning; outcome devaluation; stimuli

2. Finley JM. Bastian AJ. Associations between foot placement asymmetries and metabolic cost of transport in hemiparetic gait. Neurorehabil Neural Repair. 2016 Oct 20. pii: 154968316675428. [Epub ahead of print]
Key words: asymmetry; locomotion; metabolic cost; stroke

3. Gu Y, Huganir RL. Identification of the SNARE complex mediating the exocytosis of NMDA receptors.
Proc Natl Acad Sci USA. 2016 Oct 25;113(43):12280-12285. Epub 2016 Oct 6.
Key words: NMDA receptor; Rab; SNARE; TIRFM; constitutive exocytosis

4. Thein T, de Melo J, Zibetti C, Clark BS, Juarez F, Blackshaw S. Control of lens development by Lhx2-regulated neuroretinal FGFs. Development. 2016 Nov 1;143(21):3994-4002. Epub 2016 Sep 15.
Key words: lens, development, FGFs

1. Gillary G, Niebur E. The edge of stability: response times and delta oscillations in balanced networks.
PLoS Comput Biol 2016 Sep 30;12(9):e1005121. doi:10.1371/journal.pcbi.1005121.
Key words: delta oscillations, networks

2. Kwon SE, Yang H, Minamisawa G, O'Connor DH. Sensory and decision-related activity propagate in a cortical feedback loop during touch perception. Nat Neurosci 2016 Sep;19(9):1243-9. doi: 10.1038/nn.4356.
Key words: cortical feedback, touch perception

3. Na Y, Park S, Lee C, Kim DK, Park JM, Sockanathan S, Huganir RL, Worley PF. Real-time imaging reveals properties of glutamate-induced Arc/Arg 3.1 translation in neuronal dendrites. Neuron. 2016 Aug 3;91(3):561-73. doi: 10.1016/j.neuron.2016.06.017.
Key words: imaging, arc, dendrites

4. Riabinina O, Potter CJ. The Q-system: a versatile expression system for Drosophila. Methods Mol Biol. 2016;1478:53-78.
Key words: Q-system, drosophila

5. Riabinina O, Task D, Marr E, Lin CC, Alford R, O'Brochta DA, Potter CJ. Organization of olfactory centres in the malaria mosquito Anopheles gambiae. Nat Commun. 2016 Oct 3;7:13010. doi: 10.1038/ncomms13010.
Key words: olfactory, malaria, Anopheles

6. Roemmich RT, Long AW, Bastian AJ. Seeing the errors you feel enhances locomotor performance but not learning. Curr Biol. 2016 Oct 24;26(20):2707-2716.
Key words: adaptation; feedback; gait; locomotion; motor learning; split-belt treadmill; walking

7. Wang Y, Williams J, Rattner A, Wu S, Bassuk AG, Goffinet AM, Nathans J. Patterning of papillae on the mouse tongue: a system for the quantitative assessment of planar cell polarity signaling.
Dev Biol. 2016 Sep 6. pii: S0012-1606(16)30439-0. doi: 10.1016/j.ydbio.2016.09.004. [Epub ahead of print].
Key words: papillae, planar, cell, polarity

8. Weng YL, Joseph J, An R, Song H, Ming GL. Epigenetic regulation of axonal regenerative capacity.
Epigenomics. 2016 Oct;8(10):1429-1442.
Key words: epigenetic, axonal, regenerative

1. Ambrose RE, Pfeiffer BE, Foster DJ. Reverse Replay of Hippocampal Place Cells Is Uniquely Modulated by Changing Reward. Neuron. 2016 Sep 7; 91(5):1124-36. doi: 10.1016/j.neuron.2016.07.047.
Key words: replay, hippocampal, reward

2. de Melo J, Clark BS, Blackshaw S. Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis. Sci Rep. 2016 Sep 8;6:32757. doi: 10.1038/srep32757.
Key words: Lhx2, gliogenesis

3. Kim YS, Anderson M, Park K, Zheng Q, Agarwal A, Gong C, Saijilafu, Young L, He S, LaVinka PC, Zhou F, Bergles D, Hanani M,Guan Y, Spray DC,, Dong X. Coupled activation of primary sensory neurons contributes to chronic pain. Neuron. 2016 Sep 7;91(5):1085-96. doi: 10.1016/j.neuron.2016.07.044.
Key words: sensory, neurons, pain

4. Lin CC, Potter CJ. Non-Mendelian dominant maternal effects caused by CRISPR/Cas9 transgenic components in Drosophila melanogaster. G3 (Bethesda). 2016 Sep 16. pii: g3.116.034884. doi: 10.1534/g3.116.034884. [Epub ahead of print]
Key words: CRISPR/Cas9, transgenic, Drosophila

5. Lin CC, Riabinina O, Potter CJ. Olfactory behaviors assayed by computer tracking of Drosophila in a four-quadrant olfactometer. J Vis Exp. 2016 Aug 20;(114). doi: 10.3791/54346.
Key words: olfactory, behaviors, drosophila, olfactometer

6. Thein T, de Melo J, Zibetti C, Clark BS, Juarez F, Blackshaw S. Control of lens development by Lhx2-regulated neuroretinal FGFs. Development. 2016 Sep 15. pii: dev.137760. [Epub ahead of print]
Key words: lens, neuroretinal, FGFs

7. Wang Y, Williams J, Rattner A, Wu S, Bassuk AG, Goffinet AM, Nathans J. Patterning of papillae on the mouse tongue: a system for the quantitative assessment of planar cell polarity signaling. Dev Biol. 2016 Sep 6. pii: S0012-1606(16)30439-0. doi: 10.1016/j.ydbio.2016.09.004. [Epub ahead of print]
Key words: patterning, papillae, polarity

1. Diering GH, Heo S, Hussain NK, Liu B, Huganir RL. Extensive Phosphorylation of AMPA Receptors in Neurons. Proc Natl Acad Sci USA. 2016 Aug 16;113(33);E4920-7. doi:10.1073/pnas.1610631113. Epub 2016 Aug 1.
Key words: phosphorylation, AMPA, receptors

2. Jin Y, , Dougherty SE, Wood K, Sun L, Cudmore RH, Abdalla A, Kannan G, Pletnikov M, Hashemi P, Linden DJ. Regrowth of serotonin axons in the adult mouse brain following injury. Neuron. 2016 Aug 17;91(4):748-62/ doi:10.1016/j.neuron.2016.07.024. Epub 2016 Aug.
Key words: regrowth, serotonin, axons, injury

3. Kwon SE, Yang H, Minamisawa G, O'Connor DH. Sensory and decision-related activity propagate in a cortical feedback loop during touch perception. Nat Neurosci. 2016 Jul 20. doi: 10.1038/nn.4356. [Epub ahead of print].
Key words: sensory, decision, activity, touch, perception

4. Miller SJ, Rothstein JD. Astroglia in thick tissue with super resolution and cellular reconstruction. PLoS One. 2016 Aug 5;11(8):e0160391. doi: 1371/journal.pone.0160391. eCollection 2016.
Key words: astroglia, super resolution

5. Wagatsuma N, von der Heydt R, Niebur E. Spike synchrony generated by modulatory common input through NMDA-type synapses. J Neurophysiol. 2016 Jul 13;.jn.01142.2015. doi: 10:101152/jn.01142.2015. [Epub ahead of print]
Key words: spike, synchrony, modulatory, NMDA

6. Weeks HM, Therrien AS, Bastian AJ. Proprioceptive localization deficits in people with cerebellar damage. Cerebellum. 2016 Aug 18. [Epub ahead of print]
Key words: proprioceptive, cerebellar, damage

7. Wong AL, Goldsmith J, Krakauer JW. A motor planning stage represents the shape of upcoming movement trajectories. J Neurophysiol. 2016 Aug 1;116(2):296-305. doi: 10.1152/jn.01064.2015. Epub 2016 Apr 20.
Key words: omplex action; desired trajectory; motor planning; optimal feedback control; reaction time

1. Gomez-Ramirez M, Hysaj K, Niebur E. Neural mechanisms of selective attention in the somatosensory system. J Neurophysiol. 2016 Jun 22;jn.00637.2015. doi: 10.1152/jn.00637.2015. [Epub ahead of print]
Key words: selective, attention, somatosensory

2. Lin CC, Potter CJ. Editing transgenic DNA components by inducible gene replacement in drosophila melanogaster. Genetics. 2016 Jun 22. pii: genetics.116.191783. [Epub ahead of print]
Key words: editing, transgenic, DNA, drosophila

3. Martinez-Monedero R, Liu C, Weisz C, Vyas P, Fuchs PA, Glowatzki E. GluA2-containing AMPA receptors distinguish ribbon-associated from ribbonless afferent contacts on rat cochlear hair cells.
eNeuro 2016 May 12;3(2). pii: ENEURO.0078-16.2016. doi: 10.1523//ENEURO.0078-16.2016.
Key words: GluA2, ribbon, hair cells

4. Na Y, Park S, Lee C, Kim DK, Park JM, Sockanathan S, Huganir RL, Worley PF. Real-time imaging reveals properties of glutamate-induced Arc/Arg 3.1 translation in neuronal dendrites. Neuron. 2016 Jul 5. pii: S0896-6273(16)30924-X. doi: 10.1016/j.neuron.2016.06.017. [Epub ahead of print]
Key words: imaging, Arc, dendrites

5. Qu L, Caterina MJ. Enhanced excitability and suppression of A-type K (+) currents in joint sensory neurons in a murine model of antigen-induced arthritis. Sci Rep. 2016 1;6:28899. doi: 10.1038/srep28899.
Key words: excitability, murine, antigen-induced, arthritis

1. Hart RP, Goff LA. Long noncoding RNAs: central to nervous system development. Int J Dev Neurosci. 2016 Jun10. pii: S0736-5748 (16) 30109-5. doi: 10.1016/j.ijdevneu.2016.06.001. [Epub ahead of print]
Key words: long noncoding, nervous system

2. Liu S, Liu Q, Tabuchi M, Wu MN. Sleep drive is encoded by neural plastic changes in a dedicated circuit.
Cell. 2016 Jun2; 165(6): 1347-60. doi: 10.1016/j.cell.2016.04.013. Epub 2016 May 19.
Key words: sleep drive, dedicated circuit

1. Evsen L, Doetzlhofer A. Gene transfer into the chicken auditory organ by in ovo micro-electroporation.J Vis Exp. 2016 Apr 17; (110). doi: 10.3791/53864.
Key words: gene transfer, auditory, in ovo micro-electroporation

2. Fu X, Shah A, Baraban JM. Rapid reversal of translational silencing: emerging role of microRNA degradation pathways in neuronal plasticity. Neurobiol Learn Mem. 2016 Apr 20. pii: S1074-7427(16)30028-4. doi: 10.1016/j.nlm.2016.04.006. [Epub ahead of print]
Key words: translational silencing, neuronal plasticity

3. Liu S, Liu Q, Tabuchi M, Wu MN. Sleep drive is encoded by neural plastic changes in a dedicated circuit.Cell. 2016 May 18. pii: S0092-8674(16)30404-4. doi: 10.1016/j.cell2016.04.013. [Epub ahead of print]
Key words: sleep drive, dedicated circuit

4. Qian X, Nguyen HN, Song MM, Hadiono C, Ogden SC, Hammack C, Yao B, Hamersky GR, Jacob F, Yoon KJ, Jeang W, Lin L, Thakor J, Berg DA, Zhang C, Kang E, Chickering M, Nauen D, Ho CY, Wen Z, Christian KM, Shi PY, Maher BJ, Wu H, Jin P, Tang H, Song H, Ming GL. Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure. Cell. 2016 May 19;165(5):1238-54. doi: 10.1016/j.cell2016.04.032. Epub 2016 Apr 22.
Key words: organoids, mini-bioreactors, ZIKV

5. Zhang K, Grima JC, Rothstein JD, Lloyd TE. Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD. Nucleus. 2016 Apr 26; 1-6. [Epub ahead of print]
Key words: nucleocytoplamic transport, C9orf72, ALS/FTD

1. Musselman KE, Roemmich RT, Garrett B, Bastian AJ. Motor learning in childhood reveals distinct mechanisms for memory retention and re-learning. Learn Mem. 2016 Apr 15;23(5): 229-37. doi: 10.1101/1m.041004.115.
Key words: motor learning, childhood, memory

2. Xu JC, Fan J, Wang X, Eacker SM, Kam TI, Chen L, Yin X, Zhu J, Chi Z, Jiang H, Chen R, Dawson TM, Dawson VL. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med. 2016 Apr 6; 8(333):333ra48. doi: 10.1126/scitranslmed.aad0623.
Key words: projection, neurons, neurotoxicity

1. Corbit LH, Fischbach SC, Janak PH. Nucleus accumbens core and shell are differentially involved in general and outcome-specific forms of pavlovian-instrumental transfer with alcohol and sucrose rewards. Eur J Neurosci. 2016 Mar 11. doi:10.1111/ejn.13235. [Epub ahead of print]
Key words: nucleus accumbens, alcohol, sucrose, rewards, incentive, learning, motivation, stimulus, ventral striatum

2. de Melo J, Zibetti C, Clark BS, Hwang W, Miranda-Angulo AL, Qian J, Blackshaw S. Lhx2 is an essential factor for retinal gliogenesis and notch signaling. J Neurosci. 2016 Feb 24;36(8):2391-405. doi:10.1523/JNEUROSCI.3145-15.2016.
Key words: Lhx2; retinal gliogenesis; Müller glia; Notch; differentiation; retina

3. Haith AM, Pakpoor J, Krakauer JW. Independence of movement preparation and movement initiation.
J Neurosci. 2016 Mar 9;36(10):3007-15. doi:10.1523/JNEUROSCI.3245-15.2016.
Key words: preparation, movement, initiation

4. Lagerlöf O, Slocomb JE, Hong I, Aponte Y, Blackshaw S, Hart GW, Huganir RL. The nutrient sensor OGT in PVN neurons regulates feeding. Science. 2016 Mar 18;351(6279):1293-6. Doi:10.1126/science.aad5494.
Key words: OGT, PVN, feeding

5. Long AW, Roemmich RT, Bastian A. Blocking trial-by-trial error correction does not interfere with motor learning in human walking. J Neurophysiol 2016 Feb 24:jn.00941.2015. doi:10.1152/jn.00941.2015. [Epub ahead of print]
Key words: motor learning, adaptation, feedback, gait, human walking.

6. Mo A, Luo C, David FP, Mukamel EA, Henry GL, Nery JR, Urich MA, Picard S, Lister R, Eddy SR, Beer MA, Ecker JR, Nathans J. Epigenomic landscapes of retinal rods and cones. Elife. 2016 Mar 7;5. pii:e11613. Doi:10.7554/eLife.11613.
Key words: epigenomic, retinal, rods, cones

7. Statton MA, Toliver A, Bastian AJ. A dual-learning paradigm can simultaneously train multiple characteristics of walking. J Neurophysiol 2016 Mar 9:jn.00090.2016. doi: 10.1152/jn.00090.2016. [Epub ahead of print]
Key words: dual-learning, walking

8. Vaziri S, Connor CE. Representation of gravity-aligned scene structure in ventral pathway visual cortex.
Curr Biol. 2016 Feb 23. pii: S0960-9822(16)00072-5. doi:10.1016/j.cub.2016.01.022.
Key words: gravity-aligned, visual cortex

1. Gu Y, Chiu SL, Liu B, Wu PH, Delannoy M, Lin DT, Wirtz D, Huganir RL. Differential vesicular sorting of AMPA and GABAA receptors. Proc Natl Acad Sci USA. 2016 Feb 16;113(7):E922-31. doi: 10.1073/pnas.152726113. Epub 2016 Feb 2.
Key words: vesicular, sorting, receptors

2. Kim J, Matney CJ, Roth RH, Brown SP. Synaptic organization of the neuronal circuits of the claustrum.
J Neurosci. 2016 Jan 20;36(3):773-84. doi: 10.1523/JNEUROSCI.3643-15.2016.
Key words: claustrum

3. Wang H, Ardiles AO, Yang S, Tran T, Posada-Duque R, Valdivia G, Back M, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A. Metabotropic glutmate receptors induce a form of LTP controlled by translation and arc signaling in the hippocampus. J Neurosci. 2016 Feb 3; 36(5):1723-9. doi: 10.1523/JNEUROSCI.0878-15.2016.
Key words: LTP, translation, arc

4. Zeng Y, Yao B, Shin J, Lin L, Kim N, Song Q, Liu S, Su Y, Guo JU, Huang L, Wan J, Wu H, Qian J, Cheng X, Zhu H, Ming GL, Jin P, Song H. Lin28A binds active promoters and recruits Tet1 to regulate gene expression. Mol Cell. 2016 Jan7;61(1):153-60. doi:10.1016/j.molcel.2015.11.020. Epub 2015 Dec 17.
Key words: Lin28A, gene expression

1. Campbell DP, Chrysostomou E, Doetzlhofer A. Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep. 2016 Jan 20; 6:1984. doi: 10.1038/rep19484.
Key words: notch, auditory, development

2. Guha P, Harraz MM, Snyder SH. Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade. Proc Natl Acad Sci USA. 2016 Jan 19. pii: 201524860. [Epub ahead of print]
Key words: cocaine, nitric, oxide, GAPDH

3. Harraz MM, Tyagi R, Cortés P, Snyder SH. Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic rheb degradation. Mol Psychiatry. 2016 Jan 19. doi:10.1038/mp.2015.211. [Epud ahead of print]
Key words: ketamine, mTOR, Rheb

4. Hu B, Kane-Jackson R, Niebur E. A proto-object based saliency model in three-dimensional space.
Vision Res. 2015 Dec 28. pii: S0042-6989(15)00370-3. doi: 10.1016/j.visres.2015.12.004. [Epub ahead of print]
Key words: object, saliency, space

5. Zhang-Hooks Y, Agarwal A, Mishina M, Bergles DE. NMDA receptors enhance spontaneous activity and promote neuronal survival in the developing cochlea. Neuron. 2016 Jan 6. pii: S0896-6273(15)01118-6. doi:10.1016/j.neuron.2015.12.016. [Epub ahead of print]
Key words: NMDA, receptors, activity, survival, cochlea

1. Chen X, Stuphorn V. Sequential selection of economic good and action in medial frontal cortex of macaques during value-based decisions. Elife. 2015 Nov 27;4. pii: e09418. doi: 10.7554/eLife.09418. [Epub ahead of print]
Key words: macaques, value-based decisions

2. He K, Huertas M, Hong SZ, Tie X, Hell JW, Shouval H, Kirkwood A. Distinct eligibility traces for LTP and LTD in cortical synapses. Neuron. 2015 Nov 4;88(3):528-38. doi: 10.1016/j.neuron.2015.09.037.
Key words: eligibility, traces, LTP, LTD

3. Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A. Brief dark exposure reduces tonic inhibition in visual cortex. J Neurosci. 2015 Dec 2;35(48):15916-20. doi:10.1523/JNEUROSCI.1813-15.2015.
Key words: dark, exposure, visual, cortex

4. Therrien AS, Wolpert DM, Bastian AJ. Effective reinforcement learning following cerebellar damage requires a balance between exploration and motor noise. Brain. 2015 Dec 1. pii: awv329. [Epub ahead of print]
Key words: learning, cerebellar damage

5. Wang HC, Lin CC, Cheung R, Zhang-Hooks Y, Agarwal A, Ellis-Davies G, Rock J, Bergles DE. Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells.
Cell. 2015 Dec 3;163(6):1348-59. doi: 10.1016/j.cell.2015.10.070. Epub 2015 Nov 25.
Key words: spontaneous, activity, cochlear, support cells

6. Yang H, Kwon SE, Severson KS, O'Connor DH. Origins of choice-related activity in mouse somatosensory cortex. Nat Neurosci. 2015 Dec 7. doi: 10.1038/nn.4183. [Epub ahead of print]
Key words: choice, somatosensory, cortex

1. Silva D, Feng T, Foster DJ. Trajectory events across hippocampal place cells require previous experience.
Nat Neurosci. 2015 Oct 26. doi:10.1038/nn.4151. [Epub ahead of print]
Key words: trajectory, hippocampal place, experience

2. Statton MA, Encarnacion M, Celnik P, Bastian AJ. A Single bout of moderate aerobic exercise improves motor skill acquisition. PLoS One. 2015 Oct 27;10(10):e0141393. doi: 10.1371/journal.pone.014393. eCollection 2015.
Key words: aerobic exercise, motor skill acquisition

1. Hussain NK, Thomas GM, Luo J, Huganir RL. Regulation of AMPA receptor subunit GluA1 surface expression by PAK3 phosphorylation. Proc Natl Acad Sci USA. 2015 Oct 12. pii: 201518382. [Epub ahead of print]
Key words: AMPA, receptor, PAK3, phosphorylation

2. Lin CC, Prokop-Prigge KA, Preti G, Potter CJ. Food odors trigger Drosophila males to deposit a pheromone that guides aggregation and female oviposition decisions. Elife. 2015 Sep 30;4. doi: 10.7554/eLife.08688. [Epub ahead of print]
Key words: odors, drosophila, female oviposition

3. Lin CC, Potter CJ. Re-classification of Drosophila melanogaster trichoid and intermediate sensilla using fluorescence-guided single sensillum recording. PLoS One. 2015 Oct 2;10(10):e0139675. doi: 10.1371/journal.pone.0139675. eCollection 2015.
Key words: drosophila, trichoid, sensilla

4. Vazquez A, Statton MA, Busgang SA, Bastian AJ. Split-belt walking adaptation recalibrates sensorimotor estimates of leg speed, but not position or force. J Neurophysiol. 2015 Sep 30;jn.00302.2015. doi: 10.1152/jn.00302.2015. [Epub ahead of print]
Key words: split-belt walking, sensorimotor

1. Larson VA, Zhang Y, Bergles DE. Electrophysiological properties of NG2+ Cells: matching physiological studies with gene expression profiles. Brain Res. 2015 Sep 15. pii: S0006-8993(15)00708-8. doi: 10.1016/j.brainres.2015.09.010. [Epub ahead of print]
Key words: NG2+ cells, expression profiles

2. Lee H, Wang C, Deshmukh SS, Knierim JJ. Neural population evidence of functional heterogeneity along the CA3 transverse axis: pattern completion versus pattern separation. Neuron. 2015 Sep 2;87(5):1093-105. doi: 10.1016/j.neuron.2015.07.012. Epub 2015 Aug 19.
Key words: neural population, CA3, transverse axis

3. Zhang L, von der Heydt R. Visual selectivity and top-down modulation of neurons in monkey V2 during free viewing. J Vis. 2015 Sep 1;15(12):1245. doi: 10.1167/15.12.1245.
Key words: visual selectivity, V2

1. Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder S. Huntington's disease: neural dysfunction linked to inositol polyphosphate multikinase. Proc Natl Acad Sci USA. 2015 Aug 4; 112(31):9751-6. doi: 10.1073/pnas.1511810112. Epub 2015 Jul 20.
Key words: Huntington's, polyphosphate multikinase

2. Fu C, Xu J, Li RJ, Crawford JA, Khan AB, Ma TM, Cha JY, Snowman AM, Pletnikov MV, Snyder SH. Inositol hexakisphosphate kinase-3 regulates the morphology and synapse formation of cerebellar purkinje cells via spectrin/adducin. J Neurosci. 2015 Aug 5:35(31):11056-67. doi: 10.1523/JNEUROSCI.1069-15.2015.
Key words: hexakisphosphate kinase-3, cerebellar, spectrin

3. Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK. Defective age-dependent metaplasticity in a mouse model of Alzheimer's disease. J Neurosci. 2015 Aug 12;35(32):11346-57. doi: 1523/JNEUROSCI.5289-14.2015.
Key words: metaplasticity, alzheimer's disease

4. Mills EA, Davis CO, Bushong EA, Boassa D, Kim KY, Ellisman MH4 Marsh-Armstrong N. Astrocytes phagocytose focal dystrophies from shortening myelin segments in the optic nerve of Xenopus laevis at metamorphosis. Proc Natl Acad Sci USA. 2015 Aug 3. pii: 201506486. [Epub ahead of print].
Key words: astrocytes, dystrophies, Xenopus

5. Tan HL1, Queenan BN1, Huganir RL2. GRIP1 is required for homeostatic regulations of AMPAR trafficking. Proc Natl Acad Sci USA. 2015 Aug 11;112(32):11026-31. doi: 10.1073/pnas.1512786112. Epub 2015 Jul 27.
Key words: GRIP1, homeostatic, AMPAR

1. Golden EJ, Benito-Gonzalez A, Doetzlhofer A. The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci USA. 2015 Jul 21;112(29):E3864-73.
Key words: RNA-binding, LIN28B, cochlea

2. Hand RA, Khalid S, Tam E, Kolodkin AL. Axon dynamics during neocortical laminar innervation.
Cell Rep. 2015 Jul 14;12(2):172-82. doi: 10.1016/j.celrep.2015.06.026.
Key words: axon, neocortical, laminar

3. Pfeiffer BE, Foster DJ. PLACE CELLS. Autoassociative dynamics in the generation of sequences of hippocampal place cells. Science. 2015 Jul 10;349(6244):180-3. doi:10.1126/science.aaa9633.
Key words: place cells, hippocampal

1. Harraz MM, Snyder SH1. Nitric oxide-GAPDH transcriptional signaling mediates behavioral actions of cocaine. CNS Neurol Disord Drug Targets. 2015 May 29. [Epub ahead of print].
Key words: nitric oxide, cocaine

2. Petrus E, Rodriguez G, Patterson R, Connor B, Kanold PO, Lee HK. Vision loss shifts the balance of feedforward and intracortical circuits in opposite directions in mouse primary auditory and visual cortices. J Neurosci. 2015 Jun 10;35(3)8790-801. doi: 10.1523/JNEUROSCI.4975-14.2015.
Key words: vision loss, intracortical, mouse

1. Martin AB1, von der Heydt R2. Spike Synchrony Reveals Emergence of Proto-objects in Visual Cortex.
J Neurosci. 2015 Apr 29;35(17):6860-70. doi:10.1523/JNEUROSCI.3590-14.2015.
Key words: spike synchrony, cortex

2. Sun LO1, Brady CM1, Cahill H2, Al-Khindi T1, Sakuta H3, Dhande OS4, Noda M3, Huberman AD4, Nathans J2, Kolodkin AL5. Functional Assembly of Accessory Optic System Circuitry Critical for Compensatory Eye Movements.
Neuron. 2015 May 6. pii: S0896-6273(15)00288-3. doi: 10.1016/j.neuron.2015.03.064. [Epub ahead of print]
Key words: accessory optic system, eye movements

3. Toda AM1, Huganir RL2. Regulation of AMPA Receptor Phosphorylation by the Neuropeptide PACAP38.
Proc Natl Acad Sci USA. 2015 May 11. pii: 201507229. [Epub ahead of print]
Key words: AMPA, phyosphorylation, PACAP38

4. Yan Y1, Wladyka C1, Fujii J2, Sockanathan S1.. Prdx4 is a Compartment-specific H202 Sensor that Regulates Neurogenesis by Controlling Surface Expression of GDE2.
Nat Commun. 2015 May 6;6:7006. doi: 10.1038/ncomms8006.
Key words: Prdx4, H202, GDE2

1. Long AW, Finley JM, Bastian AJ. A marching-walking hybrid induces step length adaptation and transfers to natural walking. J Neurophysiol 2015 Apr 1;jn.00779.2014. doi: 10.1152/jn.00779.2014. [Epub ahead of print]
Key words: marching-walking, natural walking

2. Roemmich RT, Bastian AJ. Two ways to save a newly learned motor pattern. J Neurophysiol 2015 Apr 8;jn.00965.2014. doi: 10.1152/jn.00965.2014. [Epub ahead of print]
Key words: learned motor pattern

3. Zhang W, Wu J, Ward MD, Yang S, Chuang YA, Xiao M, Li R, Leahy DJ, Worley PF. Structural basis of arc binding to synaptic proteins: implications for cognitive disease. Neuron2015 Apr 8. pii:S0896-6273(15)00254-8. doi: 10.1016/j.neuron.2015.03.030. [Epub ahead of print]
Key words: arc, cognitive disease


1. Paul BD, Snyder SH. Protein sulfydration. Methods Enzymol.2015;555:79-90. doi: 10.1016/bs.mie.2014.11.021.
Key words: protein sulfhydration

2. Riabinina O, Luginbuhl D, Marr E, Liu S, Wu MN, Luo L, Potter CJ. Improved and expanded Q-system reagents for genetic manipulations. Nat Methods.2015 Mar;12(3):219-22. doi: 10.1038/nmeth.3250.
Key words: Q-system reagents, genetic manipulations, protein engineering, transgenic regulation

1. Rao F, Xu J, Fu C, Cha JY, Gadalla MM, Xu R, Barrow JC, Snyder SH. Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. Proc Natl Acad Sci USA. 2015 Feb 10;112(6);1773-8. doi:10.1073/pnas.1424642112.
Key words: inositol, pyrophosphates, metastasis

2. Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X. Tmem100 Is a regulator of TRPA1-TRPV1 complex and contributes to persistent pain. Neuron. 2015 Jan 28.pii: S0896-6273(14)01174-X. doi: 10.1016/j.neuron.2014.12.065.
Key words: Tmem100, persistent pain

3. Zhang Y, Cudmore RH, Lin DT, Linden DJ, Huganir RL. Visualization of NMDA receptor-dependent AMPA receptor synaptic plasticity in vivo. Nat Neurosci. 2015 Mar;18(3):402-7.
Key words: visualization, NMDA, plasticity

1. Araki Y, Zeng M, Zhang M, Huganir RL. Rapid dspersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP. Neuron. 2015 Jan 7;85(1):173-89.
Key words: SynGAP, spines, AMPA, receptor, LTP

2. McNeil BD, Pundir P, Meeker S, Han L, Undem BJ, Kulka M, Dong X. Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. Nature 2014 Dec 17. doi:10.1038/nature14022. [Epub ahead of print].
Key words: mast, cell, receptor, allergic, drug, reactions

3. Riabinina O, Luginbuhl D, Marr E, Liu S, Wu MN, Luo L, Potter CJ. Improved and expanded Q-system reagents for genetic manipulations. Nat Methods 2015 Jan 12. doi:10.1038/nmeth.3250. [Epub ahead of print].
Key words: Q-system, genetic manipulations

4. M, Yoo S, Newman EA, Wang H, Bedont JL, de Melo J, Miranda-Angulo AL , Gil-Perotin S, Garcia- Salvatierra J, Lee DA, Zibetti C, Duran-Moreno Verdugo JM, Blackshaw S. The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. J Neurosci. 2014 Dec 10:34(50):16809-20. doi: 10.1523/JNEUROSCI.1711-14.2014.
Key words: Lhx2, Tanycyte, differentiation

1. Diering GH, Gustina AS, Huganir RL. PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity.
Neuron. 2014 Nov 19;84(4):790-805.
Key words: PKA-GluA1, homeostatic, plasticity

2. Gomez-Ramirez M, Trzcinski NK, Mihalas S, Niebur E, Hsiao SS. Temporal correlation mechanisms and their role in feature selection: a single-unit study in primate somatosensory cortex.
PLoS Biol2014 Nov 25;12(11):e1002004.
Key words: temporal correlation, primate somatosensory

1. Rao F, Xu J, Khan AB, Gadalla MM, Cha JY, Xu R, Tyagi R, Dang Y, Chakraborty A, Snyder SH. Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death. Proc Natl Acad Sci USA. 2014 Nov 11;111(45):16005-10. doi:10.1073/pnas.14179000111.
Key words: CRL4, DNA repair, cell death

2. Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH. serine racemase regulated by binding to stargazin and PSD-95: potential N-methyl-d-aspartate-?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (NMDA-AMPA) glutamate neurotransmission cross-talk. J Biol Chem. 2014 Oct 24:289(43):29631-41. Doi:10.1074/jbcc.M114.571604.
Key words: serine racemase, stargazin, PSD-95, neurotransmission

1. Benito-Gonzalez A1, Doetzlhofer A2. Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of hedgehog signaling. J Neurosci. 2014 Sep 17;34(38):12865-76.
Key words: auditory, hair cell, hedgehog

2. Keller JL1, Bastian AJ2. A home balance exercise program improves walking in people with cerebellar ataxia. Neurorehabil Neural Repair. 2014 Oct:28(8):770-8.
Key words: balance, cerebellar, ataxia

3. Ramenahalli S1, Mihalas S2, Niebur E3. Local spectral anisotropy is a valid cue for figure-ground organization in natural scenes. Vision Res. 2014 Oct;103:116-26.
Key words: spectral, anisotropy, natural, scenes

4. Vaziri S1, Carlson ET1, Wang Z2, Connor CE3. A channel for 3D environmental shape in anterior inferotemporal cortex. Neuron. 2014 Oct 1;84(1):55-62.
Key words: 3D, shape, inferotemporal, cortex

5. Wang HC1, Bergles DE. Spontaneous activity in the developing auditory system. Cell Tissue Res. 2014 Oct 9. [Epub ahead of print].
Key words: activity, auditory

6. Wang SH1, Celic I1, Choi SY2, Riccomagno M1, Wang Q1, Sun LO1, Mitchell SP1, Vasiokhin V3, Huganir RL1, Kolodkin AL4. Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J Neurosci. 2014 Sep 17;34(38):12745-61.
Key words: Dlg5, dendritic, spine, cadherin

1. Ramenahalli S, Mihalas S, Niebur E. Local spectral anisotropy is a valid cue for figure-ground organization in natural scenes. Vison Res. 2014 Aug 29. pii:S0042-6989(14)00191-6. doi:10.1016/j.visres.2014.08.012. [Epub ahead of print]
Key words: spectral, anisotropy, figure-ground, organization

1. Gao M, Maynard KR, Chokshi V, Song L, Jacobs C, Wang H, Tran T, Martinowich K, Lee HK. Rebound potentiation of inhibition in juvenile visual cortex requires vision-induced BDNF expression.
J Neurosci. 2014 Aug 6;34(32):10770-9. doi:10.1523/JNEUROSCI.5454-13.2014.
Key words: visual cortex, BDNF

2. Hussain NK, Diering GH, Sole J, Anggono V, Huganir RL. Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARS.
Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11840-5. doi:10.1073/pnas.1412415111. Epub 2014 Jul 28.
Key words: Nexin 27, trafficking, AMPARs

3. Ma TM, Paul BD, Fu C, Hu S, Zhu H, Blackshaw S, Wolosker H, Snyder SH. Serine racemase regulated by binding to stargazin and PSD-95: potential NMDA-AMPA glutamate neurotransmission cross-talk.
J Biol Chem., 2014 Aug 27. pii:jbc.M114.571604. [Epub ahead of print].

1. David CH, Kim KY,Bushong EA, Mills EA, Boassa D,Shih T, Kinebuchi M, Phan S, Zhou Y, Bihlmeyer NA, Nguyen JV, Jin Y, Ellisman MH, Marsh-Armstrong N. Transcellular degradation of axonal mitochondria.
Proc Natl Acad Sci USA. 2014 Jul 1;111(26):9633-8. doi: 10.1073/pnas.1404651111.
Key words: degradation, mitochondria

2. Kim J, Matney CJ, Blankenship A, Hestrin S, Brown SP. Layer 6 corticothalamic neurons activate a cortical output layer, layer 5a. J Neurosci. 2014 Jul 16;34(29):9656-64. doi:10.1523/JNEUROSCI.1325-14.2014.
Key words: cortical output, layer 5a

3. Lee DA, You S, Pak T, Salvatierra J, Velarde E, Aja S, Blackshaw S. Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice. Front Neurosci. 2014 Jun13;8:157. doi: 10.3389/fnins.2014.00157.
Key words: hypothalamic neurogenesis

4. Paukert M, Agarwal A, Cha J, Doze VA, Kang JU, Bergles DE. Norepinephrine controls astroglial responsiveness to local circuit activity. Neuron. 2014 Jun 18;82(6):1263-70. doi:10.1016/j.neuron.2014.04.038.
Key words: norepinephrine, circuit activity

1. Bai Y, Lathia JD, Zhang P, Flavahan W, Rich JN, Mattson MP. Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells. Glia. 2014 Jun 7. doi: 10.1002/glia.22708.
Key words: TRF2, glioblastoma

2. Baxi EG, Schott JT, Fairchild AN, Kirby LA, Karani R, Uapinyoying P, Pardo-Villamizar C, Rothstein JR, Bergles DE, Calabresi PA. A selective thyroid hormone ? receptor agonist enhances human and rodent oligodendrocyte differentiation. Glia. 2014 May 24. doi:10.1002/glia.22697.
Key words: thyroid hormone, oligodendrocyte

3. Huang S, Rozas C, Treviño M, Contreras J, Yang S, Song L, Yoshioka T, Lee HK, Kirkwood A. Associative hebbian synaptic plasticity in primate visual cortex. J Neurosci. 2014 May 28;34(22):7575-9. doi:10.1523/JNEUROSCI.0983-14.2014.
Key words: synaptic plasticity, primate visual cortex

4. Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, Tang Z, Han L, Chu YX, Wang Y, Hin N, Tsukamoto T, Slusher B, Guan X, Wei F, Raja SN, Dong X, Guan Y. Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice. Pain. 2014 May 9. pii:S0304-3959(14)00228-0. doi: 10.1016/j.pain.2014.05.008.
Key words: MrgC receptor, sensory neurons

5. Monaco JD, Rao G, Roth ED, Knierim JJ. Attentive scanning behavior drives one-trial potentiation of hippocampal place fields.
Nat Neurosci. 2014 May;17(5):725-31. doi: 10.1038/nn.3687.
Key words: hippocampal place fields

6. Zhong X, Gutierrez C, Xue T, Hampton C, Vergara MN, Cao LH, Peters A, Park TS, Zambidis ET, Meyer JS, Gamm DM, Yau KW, Canto-Soler MV. Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047. doi:10.1038/ncomms5047.
Key words: three-dimensional retinal tissue, iPSCs

1. Bedont JL, Legates TA, Slat EA, Byerly MS, Wang H, Hu J, Rupp AC, Qian J, Wong GW, Herzog ED, Hattar S, Blackshaw S. Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus. Cell Rep. 2014 Apr 23. pii:S2211-1247(14)00257-5.
Key words: Lhx1, circadian function, suprachiasmatic

2. Bhanpuri NH, Okamura AM, Bastian AJ. Predicting and correcting ataxia using a model of cerebellar function. Brain. 2014 May 8. [Epub ahead of print]
Key words: ataxia, cerebellar function

3. Gwilliam JC, Yoshioka T, Okamura AM, Hsiao SS. Neural coding of lump detection in compliant artificial tissue. J Neurophysiol. 2014 May 7. [Epub ahead of print]
Key words: neural coding, compliant artificial tissue

4. Wan R, Weigand LA, Bateman R, Griffioen K, Mendelowitz D, Mattson MP. Evidence that BDNF regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability.
J Neurochem. 2014 May;129(4):573-80. [Epub 2014 Feb 10]
Key words: BDNF, heart rate, parasympathetic

5. Wu X, Foster DJ. Hippocampal replay captures the unique topological structure of a novel environment.
J Neurosci. 2014 May 7;34(19):6459-69.
Key words: hippocampal replay, novel environment

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