May 2013
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Molecular Biology and Genetics Archives

1. Benachenhou F, Sperber GO, Bongcam-Rudloff E, Andersson G, Boeke JD, Blomberg J. Conserved structure and inferred evolutionary history of long terminal repeats (LTRs).Mob DNA. 2013 Feb 1;4(1):5.
Key words: LTRs, U3-R-U5 portions
http://www.mobilednajournal.com/content/4/1/5/abstract
PMID: 23369192

2. Huang CR, Burns KH, Boeke JD. Active transposition in genomes. Annu Rev Genet. 2012;46:651-75. doi: 10.1146/annurev-genet-110711-155616.
Key words: transposons, somatic mutation, retrotransposon, polymorphism, genome dynamics
http://www.annualreviews.org/doi/full/10.1146/annurev-genet-110711-155616?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed&
PMID:23145912

3. Huang Q, Purzycka KJ, Lusvarghi S, Li D, Legrice SF, Boeke JD. Retrotransposon Ty1 RNA contains a 5'-terminal long-range pseudoknot required for efficient reverse transcription. RNA. 2013 Mar;19(3):320-32.
Key words: Ty1 retrotransposon, RNA structure; retrotransposon; reverse transcription; pseudoknot; SHAPE
http://rnajournal.cshlp.org/content/early/2013/01/15/rna.035535.112.long
PMID: 23329695

4. Li X, Ewis H, Hice RH, Malani N, Parker N, Zhou L, Feschotte C, Bushman FD, Atkinson PW, Craig NL. A resurrected mammalian hAT transposable element and a closely related insect element are highly active in human cell culture. PNAS. 2013; 110(6):E478-87;
Key words: hAT element, target site selection, gene therapy, insertional mutagenesis
www.ncbi.nlm.nih.gov/pubmed/23091042

5. Lu, JY, Lin YY, Boeke JD, Zhu H. Using functional proteome microarrays to study protein lysine acetylation. Methods Mol Biol. 2013;981:151-65. doi: 10.1007/978-1-62703-305-3_12.
Key words: Acetylation, proteome microarrays
http://link.springer.com/protocol/10.1007%2F978-1-62703-305-3_12
PMID: 23381860

6. Mitra R, Li X, Kapusta A, Mayhew D, Mitra RD, Feschotte C, Craig NL. Functional characterization of piggyBat from the bat Myotis lucifugus unveils an active mammalian DNA transposon. Proc. Nat'l Acad. Sci. U.S.A. 2013; 110(1):234-239.
Key words: genome evolution, mobile genetic element
www.ncbi.nlm.nih.gov/pubmed/23248290

7. Woodard LE, Li X, Malani N, Kaja A, Hice RH, Atkinson PW, Bushman FD, Craig
NL, Wilson MH. Comparative analysis of the recently discovered hAT transposon
TcBuster in human cells. PLoS ONE. 2012; 7(11):e42666.
Key words: TcBuster; HEK-293; transposase, transposon
http://dx.plos.org/10.1371/journal.pone.0042666
PMID:23166581

8. Wang JT, Seydoux G. Germ cell specification. Adv Exp Med Biol. 2013;757:17-39.
Key words: germ cell, germ plasm, RNA
http://www.springerlink.com/content/p1270wk447k75012/
PMID:22872473

9. Yu H, Ye X, Guo N, Nathans J. Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes. Development. 2012 Dec;139(23):4383-94.
Key words: frizzled 2, frizzled 7, ventricular septum, ventricular palate
http://dev.biologists.org/content/139/23/4383.long
PMID: 23095888

1. Burnight ER, Staber JM, Korsakov P, Li X, Brett BT, Scheetz TE, Craig NL, McCray PB Jr. A hyperactive transposase promotes persistent gene transfer of a piggyBac DNAtransposon. Molecular Therapy-Nucleic Acids. 2012; 1, e50.
Key words: hepatocyte; liver; mouse; transposase; transposon
http://www.nature.com/mtna/journal/v1/n10/full/mtna201212a.html
no PMID available

2. Huang CR, Burns KH, Boeke JD. Active transposition in genomes. Annu Rev Genet. 2012 Dec 15;46:651-75.
Key words: transposons, somatic mutation, retrotransposon, polymorphism, genome dynamics
http://www.annualreviews.org/doi/full/10.1146/annurev-genet-110711-155616?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed&
PMID: 23145912

3. Voronina E, Paix A, Seydoux G. The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells. Development. 2012 Oct;139(20):3732-40.
http://dev.biologists.org/content/139/20/3732.long
PMID: 22991439

4. Wang JT, Seydoux G. Germ cell specification. Adv Exp Med Biol. 2013;757:17-39.
Key words: germ cells
http://www.springerlink.com/content/p1270wk447k75012/
PMID: 22872473

5. Woodard LE, Malani N, Kaja A, Hice RH, Atkinson PW, Bushman FD, Craig NL, Wilson MH. Comparative analysis of the recently discovered hAT transposonTcBuster in human cells. PLoS ONE. 2012; 7(11):e42666.
Key words: TcBuster; HEK-293; transposase, transposon
http://dx.plos.org/10.1371/journal.pone.0042666
PMID: 23166581

6. Yu H, Ye X, Guo N, Nathans J. Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes. Development. 2012 Dec;139(23):4383-94.
Key words: ventricular septum, palate, frizzled 2, frizzled 7
http://dev.biologists.org/content/139/23/4383.long
PMID: 23095888

1. Dancy BM, Crump NT, Peterson DJ, Mukherjee C, Bowers EM, Ahn YH, Yoshida M, Zhang J, Mahadevan LC, Meyers DJ, Boeke JD, Cole PA. Live-cell studies of p300/CBP histone acetyltransferase activity and inhibition. 2012 Sep 24;13(14):2113-21.
Key words: drug design, enzymes; FRET; histone H4; protein modifications
http://onlinelibrary.wiley.com/doi/10.1002/cbic.201200381/abstract;jsessionid=
B1C90EF43380454DBBD67EB932581FFE.d03t02
PMID: 22961914

2. Dai L, Taylor MS, O'Donnell KA, Boeke JD. Poly(A) binding protein C1 is essential for efficient L1 retrotransposition and affects L1 RNP formation. 2012 Aug 20. [Epub ahead of print].
Key words: poly binding proteins, L1 RNP, polyadenylation
http://mcb.asm.org/content/early/2012/08/14/MCB.06785-11.long
PMID: 22907758

3. Lee SJ, Huynh TV, Lee YS, Sebald SM, Wilcox-Adelman SA, Iwamori N, Lepper C, Matzuk MM, Fan CM. Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2353-60.
Key words: activin receptors, GDF-8, follistatin
http://www.ncbi.nlm.nih.gov/pubmed/22869749

1. Baker RP, Urban S. Architectural and thermodynamic principles underlying intramembrane protease function. Nature Chemical Biology. 2012 Jul 15;8(9):759-68.
Key words: intramembrane protease function
http://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.1021.html
PMID: 22797666

2. Greider CW. Wnt regulates TERT--putting the horse before the cart. Science. 2012 June; 336:1519-20.
Key words: telomeres, telomerase, chromosomes
http://www.sciencemag.org/content/336/6088/1519.full
PMID: 22723405

3. Shoemaker CJ, Green R. Translation drives mRNA quality control. Nat Struct Mol Biol. 2012 Jun 5;19(6):594-601.
Key words: mRNA, translation
http://www.nature.com/nsmb/journal/v19/n6/full/nsmb.2301.html
PMID: 22664987

4. Zhou Y, Moin SM, Urban S, Zhang Y. An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency. Structure. 2012 Jul 3;20(7):1255-63.
Key words: rhomboid intramembrane protease, catalytic efficiency, GlpG
http://www.cell.com/structure/abstract/S0969-2126(12)00182-7

1. Djuranovic S, Nahvi A, Green R. miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science. 2012 Apr 13;336(6078):237-40.
http://www.sciencemag.org/content/336/6078/237.short
PMID: 22499947

2. Petropoulos AD, Green R. Further in vitro exploration fails to support the allosteric three-site model. J Biol Chem. 2012 Apr 6;287(15):11642-8.
Key words: allosteric model, in vitro
http://www.jbc.org/content/287/15/11642.long
PMID: 22378789

3. Shoemaker CJ, Green R. Translation drives mRNA quality control. Nat Struct Mol Biol. 2012 Jun 5;19(6):594-601.
Key words: translation, mRNA
http://www.ncbi.nlm.nih.gov/pubmed/22664987

4. Strong MA, Vidal-Cardenas SL, Karim B, Yu H, Guo N, Greider CW. Phenotypes in mTERT?/? and mTERT?/? mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase. Mol Cell Biol. 2011 Jun;31(12):2369-79. Epub 2011 Apr 4.
Key words: telomeres, telomerase reverse transcriptase
http://mcb.asm.org/content/31/12/2369.long

1. Cooper CL, Hardy RR, Reth M, Desiderio S. Cell-nonautonomous hedgehod signaling promotes murine B lumphopoiesis from hematopoietic progenitors. Blood. 2012 April 18. [Epub ahead of print].
Key words: hedgehog signaling, lymphopoiesis, hematopoietic progenitors
http://bloodjournal.hematologylibrary.org/content/early/2012/04/18/blood-2011-12-397976.long
PMID: 22517907

1. Urban S, Dickey SW. A decade of rhomboid proteases; charting progress on mechanism and function. Genome Biology. 2011 Oct 27; 12(10): 231-41.
Key words: rhomboid, proteases
http://genomebiology.com/content/12/10/231
PMID:22035660

1. Cai Y, Boeke JD. Genome remodeling. Nat Biotechnol. 2011 Sept 8;29(9):807-8.
Key words: Synthetic Biology, MAGE, CAGE, Genome Engineering
http://www.nature.com/nbt/journal/v29/n9/full/nbt.1964.html
PMID: 21904325

2. Doherty JE, Huye L, Yusa K, Zhou L, Craig NL, Wilson M. Hyperactive piggyBac gene transfer in human cells and in vivo. Hum Gene Ther. 2011 Oct 12 [Epub ahead of print].
Key words: transgenesis, hyperactive piggyBac, Sleeping Beauty, transposon comparison
PMID: 21992617
http://www.liebertonline.com/doi/abs/10.1089/hum.2011.138

3. Dymond JS, Richardson SM, Coombes C, Babatz T, Muller S, Annaluru N, Blake WJ, Schwerzmann JW, Dai J, Lindstrom DL, Boeke A, Gottschling DE, Chandrasegaran S, Bader JS, Boeke JD. Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature. 2011 Sep 14;477(7365):471-6
Key words: synthetic biology, yeast, genomics, SCRaMbLE
http://www.nature.com/nature/journal/v477/n7365/full/nature10403.html
PMID: 21918511

4. Griffin EE, Odde DJ, Seydoux G. Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle. Cell. 2011 Sep 16;146(6):955-68.
Key words: regulation, MEX-5, kinase/phosphatase
PMID: 21925318
http://www.sciencedirect.com/science/article/pii/S0092867411009354

5. Li MA, Turner D, Ning Z, Yusa K, Liang Q, Eckert S, Rad L, Fitzgerald T, Craig NL, Bradley A. Mobilization of giant piggyBac transposons in the mouse genome. Nucleic Acids Res. 2011 Sept 24 [Epub ahead of print}.
Key words: transgenesis, hyperactive piggyBac, suppression of length-dependent reduction in transposition
PMID: 21948799
http://nar.oxfordjournals.org/content/early/2011/09/24/nar.gkr764.long

6. Li Z, Craig NL, Peters JE Transposon Tn7. In: Bacterial Integrative Mobile Genetic
Elements. 2011 (ed. Roberts AP, Mullany P) Landes Bioscience/Madame Curie Bioscience Database.
Key words: site-specific insertion, attTn7, ATP-control of transposition, two-peptide transposase, targeting by the processivity factor

7. Lu JY, Lin YY, Sheu JC, Wu JT, Lee FJ, Chen Y, Lin MI, Chiang FT, Tai TY, Berger SL, Zhao Y, Tsai KS, Zhu H, Chuang LM, Boeke JD. Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell. Sep 16;146(6):969-79.
Key words: Acetylation, AMPK, replicative lifespan, Sip2, Snf1, Sch9, intrinsic aging
http://www.sciencedirect.com/science/article/pii/S0092867411008889
PMID: 21906795

8. Motegi F, Zonies S, Hao Y, Cuenca AA, Griffin E, Seydoux G.Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes. Nat Cell Biol. 2011 Oct 9;13(11):1361-7.
PMID: 21983565
http://www.nature.com/ncb/journal/v13/n11/full/ncb2354.html

9. Zaher HS, Green R. A primary role for release factor 3 in quality control during translation elongation in Escherichia coli. Cell. 2011 Oct 14;147(2):396-408.
Key words: release factor 3, translation, E. coli
PMID: 22000017
http://www.sciencedirect.com/science/article/pii/S009286741101066X

1. Cai Y, Boeke JD. Genome remodeling. Nat Biotechnol. 2011 Sep 8;29(9):807-8.
Key words: genome, remodelin
http://www.nature.com/nbt/journal/v29/n9/full/nbt.1964.html
PMID: 21904325

2. Ortiz-Meoz RF, Green R. Helix 69 is key for uniformity during substrate selection on the ribosome. J Biol Chem. 2011 Jul 22;286(29):25604-10.
Key words: Helix 69, substrate, ribosome
http://www.jbc.org/content/286/29/25604.long
PMID: 21622559

3. Matsuoka RL, Chivatakarn O, Badea TC, Samuels IS, Cahill H, Katayama K, Kumar SR, Suto F, Chédotal A, Peachey NS, Nathans J, Yoshida Y, Giger RJ, Kolodkin AL. Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron. 2011 Aug 11;71(3):460-73.
Key words: semaphorins, retinal lamination
http://www.sciencedirect.com/science/article/pii/S0896627311005137
PMID: 21835343

4. Cahill H, Rattner A, Nathans J. Preclinical assessment of CNS drug action using eye movements in mice. J Clin Invest. 2011 Sep 1;121(9):3528-41. doi: 10.1172/JCI45557. Epub 2011 Aug 8.
Key words: central nervous system, drug action, eye movement, mice
http://www.jci.org/articles/view/45557
PMID:21821912

5. Voronina E, Seydoux G, Sassone-Corsi P, Nagamori I. RNA granules in germ cells. Cold Spring Harb Perspect Biol. 2011 Jul 18.
http://cshperspectives.cshlp.org/content/early/2011/07/18/cshperspect.a002774.long
PMID: 21768607

1. Dai L, Huang Q, Boeke JD. Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochem. 2011 May 5;12(1):18. [Epub ahead of print]
Key words: reverse transcriptase inhibitors, LINE-1, retrotransposition http://www.biomedcentral.com/1471-2091/12/18
PMID: 21545744

2. Strong MA, Vidal-Cardenas SL, Karim B, Yu H, Guo N, Greider CW. Phenotypes in mTERT+/- and mTERT-/- mice are due to short telomeres, not telomere-independent functions of TERT. Mol Cell Biol. 2011 Jun;31(12):2369-79.
Key words: phenotypes, telomeres, mice
http://mcb.asm.org/cgi/reprint/MCB.05312-11v1?view=long&pmid=21464209
PMID: 21464209

3. Yu Q, Olsen L, Zhang X, Boeke JD, Bi X. Differential contributions of histone H3 and H4 residues to heterochromatin structure. Genetics. Mar 24. 2011 [Epub ahead of print]
Key words: histone H3, histone H4, heterochromatin
http://www.genetics.org/content/early/2011/03/24/genetics.111.127886.long
PMID: 21441216

1. An W, Dai L, Niewiadomska AM, Yetil A, O'Donnell KA, Han JS, Boeke JD. Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs. Mob DNA. 2011 Feb 14;2(1):2.
Key words: LINE-1 retrotransposon; DNA
http://www.mobilednajournal.com/content/2/1/2/abstract
PMID: 21320307

2. Djuranovic S, Nahvi A, Green R. A parsimonious model for gene regulation by miRNAs. Science. 2011 Feb 4;331(6017):550-3. Review.
Key words: gene, miRNA
http://www.sciencemag.org/content/331/6017/550.short
PMID: 21292970

3. Li L, Zhang L, Fan J, Greenberg K, Desiderio S, Rassool FV, Small D. Defective non-homologous end joining blocks B-cell development in FLT3/ITD mice. Blood. 2011 Mar 17;117(11):3131-9.
Key words: B-cell, mice, FLT3/ITD
http://bloodjournal.hematologylibrary.org/cgi/reprint/blood-2010-05-286070v1
PMID: 21228325

4. Ye X, Wang Y, Rattner A, Nathans J. Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development. 2011 Mar;138(6):1161-72.
Key words: genetics, frizzled 4, frizzled 8, kidney, ureter
http://dev.biologists.org/content/138/6/1161.long
PMID: 21343368

5. Zhang L, Reynolds TL, Shan X, Desiderio S. Coupling of v(d)j recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis. Cell Press Immunity. 2011 Feb 25;34(2):163-74.
Key words: gene segment, cell cycle, cycle transition, lymphoid malignancies
http://www.ncbi.nlm.nih.gov/pubmed/21349429
PMID: 21349429

1. Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, Lin YY, Bowers EM, Mukherjee C, Song WJ, Longo PA, Leahy DJ, Hussain MA, Tschöp MH, Boeke JD,Cole PA. Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor. Science. 2010 Dec 17;330(6011):1689-92.
Key words: ghrelin, obesity, diabetes, goat, acyltransferase
http://www.sciencemag.org/content/330/6011/1689.full.pdf
PMID: 2109790

2. Cai, J., Zhang, N., Zheng, Y., de Wilde, R.F., Maitra, A., and Pan, D. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev. 2010 Nov 1, 24(21): 2383-2388.
Key words: Hippo signaling, regeneration, intestine, mouse genetics, cancer
http://genesdev.cshlp.org/content/24/21/2383.long
PMID: 21041407

3. Desiderio S. Temporal and spatial regulatory functions of the V(D)J recombinase Semin Immunol 2010 Dec;22(6):362-9.
Key words: Recombination, Lymphocyte development, Epigenetic control, Histone methylation, Plant homeodomain, Cell cycle, DNA repair, Protein degradation, Ubiquitin
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WX3-51BWXS0-
1&_user=75682&_coverDate=12%2F31%2F2010&_rdoc=1&_fmt=high&_orig=
search&_origin=search&_sort=d&_docanchor=&view=c&_acct=C000006078&_version=
1&_urlVersion=0&_userid=75682&md5=5d120d346371adb50d69d799e5f9c047&
searchtype=a
PMID: 21036059

4. Gangadharan S., Mularoni L, Fain-Thornton J, Wheelan SJ, Craig NL DNA transposon Hermes inserts into DNA in nucleosome-free regions in vivo. Proc Natl Acad Sci USA 2010 Dec 21;107(51):21966-72.
Key words: target site preference, integration, hAT element, next gen sequencing
http://www.pnas.org/cgi/doi/10.1073/pnas.1016382107
PMID: 21131571

5. Sens KL, Zhang S, Jin P, Duan D, Zhang G, Luo F, Parachini L, Chen EH. An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. J Cell Biol. 2010 Nov 29;191(5):1013-27.
Key words: myoblast fusion, podosome, fusogenic synapse
http://www.ncbi.nlm.nih.gov/pubmed/21098115

6. Xie Y, Rosser JM, Thompson TL, Boeke JD, An W. Characterization of L1 retrotransposition with high-throughput dual-luciferase assays. Nucleic Acid Research. 2010 Nov 10. [Epub ahead of print]
Key words: retrotransposition, L1, ?-globin, luciferase
http://nar.oxfordjournals.org/content/early/2010/11/10/nar.gkq1076.full.pdf+html
PMID: 21071410

7. Yusa K, Zhou L, Li MA, Bradley A, Craig NL. a hyperactive piggyBac transposase for mammalian applications. Proc Natl Acad Sci USA 2011 Jan 25;108(4):1531-6.
Key words: reprogramming, gene correction
PMID: 21205896

1. Wang Y, Chang H, Nathans J. When whorls collide: the development of hair patterns in frizzled 6 mutant mice. Development. 2010 Dec;137(23):4091-9.
Key words: hair patterns, mice, frizzled 6
http://dev.biologists.org/content/137/23/4091.long
PMID: 21062866

1. Ye X, Smallwood P, Nathans J. Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain. Gene Expr Patterns. 2010 Nov 3 [Epub ahead of print].
Key words: Norrie disease gene, mouse, eye, ear, brain
http://www.ncbi.nlm.nih.gov/pubmed/21055480

1. Badea TC, Nathans J. Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: Analysis of wild type and mutant cells using genetically-directed sparse labeling. Vision Res. 2010 Sep 6. [Epub ahead of print]
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0W-50YF6F1-2&_user=
75682&_coverDate=09%2F06%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=
search&_sort=d&_docanchor=&view=c&_acct=C000006078&_version=1&_urlVersion=
0&_userid=75682&md5=b50c7fa694fabb82c535b4d459186ae1&searchtype=a
PMID: 20826176

2. Chaconas G, Craig N, Curcio MJ, Deininger P, Feschotte C, Levin H, Rice PA, Voytas
DF. Meeting Report for Mobile DNA 2010. Mob DNA 2010 Aug 24; 1(1):20.
Key words: Transposition, Conservative Site-Specific Recombination, Retrotransposons
http://www.ncbi.nlm.nih.gov/pubmed/20735816

3. Chuang N, Mori S, Yamamoto A, Jiang H, Ye X, Xu X, Richards LJ, Nathans J, Miller MI, Toga AW, Sidman RL, Zhang J. An MRI-based atlas and database of the developing mouse brain. Neuroimage. 2011 Jan 1;54(1):80-9.
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-50KWFY2-8&_user=
75682&_coverDate=07%2F23%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=
search&_sort=d&_docanchor=&view=c&_acct=C000006078&_version=1&_urlVersion=
0&_userid=75682&md5=85c12dd59c1927a3b8015c36b994cff0&searchtype=a
PMID: 20656042

4. Dai J, Hyland EM, Norris A, Boeke JD. Genetics. 2010 Aug 16. [Epub ahead of print]
Yin and yang of histone H2B roles in silencing and longevity: a tale of two arginines. Genetics. 2010 Aug 16. [Epub ahead of print]
Key words: histone; gene silencing; heterochromatin; life-span; ageing
http://www.genetics.org/cgi/rapidpdf/genetics.110.118489v1
PMID: 20713692

5. Greider CW. Telomerase Discovery: The Excitement of Putting Together Pieces of the Puzzle (Nobel Lecture). Angew Chem Int Ed Engl.
http://onlinelibrary.wiley.com/doi/10.1002/anie.201002408/abstract

6. Holder JW, Craig NL. Architecture of the Tn7 post-transposition complex: an elaborate
nucleoprotein structure. J Mol Biol 2010 Aug 13; 401(2):167-81.
Key words: transposition; transposase, nucleoprotein complex; expressed protein
ligation, DNA footprinting

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WK7-508FF4V-2&_user=
75682&_coverDate=08%2F13%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=
search&_sort=d&_docanchor=&view=c&_acct=C000006078&_version=1&_urlVersion=
0&_userid=75682&md5=587eb5acc414cf771986026646cc2453&searchtype=a
PMID: 20538004

7. Ling, C., Zheng, Y., Yin, F., Yu, J., Huang, J., Hong, Y., Wu, S., and Pan, D. The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc. Natl. Acad. Sci. USA 2010; 107: 10532-10537.
Key words: Hippo signaling, apical basal polarity, organ size, genetics, Drosophila
http://www.pnas.org/content/107/23/10532.full
PMID: 20498073

8. Ortiz-Meoz RF, Green R. Functional elucidation of a key contact between the tRNA and the large ribosomal subunit rRNA during decoding. RNA. 2010 Oct;16(10):2002-13.
Key words: tRNA, rRNA, ribosome
http://rnajournal.cshlp.org/content/16/10/2002.long
PMID: 20739608

9. Shoemaker CJ, Eyler DE, Green R. Dom34:Hbs1 promotes subunit dissociation and peptidyl-tRNA drop-off to initiate no-go decay. Science. 2010 Oct 15;330(6002):369-72.
Key words: tRNA, Dom34:Hbs1, peptidyl
http://www.sciencemag.org/cgi/content/abstract/330/6002/369
PMID: 20947765

10. Ye X, Wang Y, Nathans J. The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease. Trends Mol Med. 2010 Aug 3. [Epub ahead of print]
Key words: Norrin/Frizzled4 pathway, retinal vascular development
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W7J-50P9T59-1&_user=
75682&_coverDate=09%2F30%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=
search&_sort=d&_docanchor=&view=c&_acct=C000006078&_version=1&_urlVersion=
0&_userid=75682&md5=2188b9081cbc445f3263b42a12f3a124&searchtype=a
PMID: 20688566

11. Yu H, Smallwood PM, Wang Y, Vidaltamayo R, Reed R, Nathans J. Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes. Development. 2010 Nov;137(21):3707-17.
Key words: Frizzled genes, tissue fusion
http://dev.biologists.org/content/137/21/3707.long
PMID: 20940229

12. Zaher HS, Green R. Kinetic basis for global loss of fidelity arising from mismatches in the P-site codon: anticodon helix. RNA 2010 Oct; 16(10):1980-9.
Key words: kinetic, P-site codon, helix
http://rnajournal.cshlp.org/content/16/10/1980.long
PMID: 20724456

1. Chaconas G, Craig N, Curcio MJ, Deininger P, Feschotte C, Levin H, Rice PA, Voytas DF. Meeting report for mobile DNA 2010. Mob DNA 2010 Aug 24; 1(1):20.
Key words: transposition, conservative site-specific recombination, retrotransposons
http://www.ncbi.nlm.nih.gov/pubmed/20735816

2. Holder JW, Craig NL. Architecture of the Tn7 Post-Transposition Complex: an elaborate nucleoprotein structure. J Mol Biol. 2010 Aug 13;401(2):167-81.
Key words: transposition; transposase, nucleoprotein complex; expressed protein ligation, DNA footprinting
http://www.ncbi.nlm.nih.gov/pubmed/20538004

3. Huang CR, Schneider AM, Lu Y, Niranjan T, Shen P, Robinson MA, Steranka JP, Valle D, Civin CI, Wang T, Wheelan SJ, Ji H, Boeke JD, Burns KH. Mobile interspersed repeats are major structural variants in the human genome. Cell. 2010 Jun 25;141(7):1171-82.
Key words: LINE1, Retrotransposon, Structural Variants, Repeats, Insertions
http://www.ncbi.nlm.nih.gov/pubmed/20602999

4. Mitra R, Mckenzie GJ, Yi L, Lee CA, Craig NL. Characterization of the TnsD-attTn7 complex that promotes site-specific insertion of Tn7. Mobile DNA 2010 Jul 23;1(1):18.
Key words: Tn7 Transposition, Target DNA binding, Zinc finger domain, Challenged phage assay, Protein-Protein interaction
http://www.mobilednajournal.com/content/1/1/18
PMID: 20653944

5. Pan X, Reissman S, Douglas NR, Huang Z, Yuan DS, Wang X, McCaffery JM, Frydman J, Boeke JD. Trivalent arsenic inhibits the functions of chaperonin complex. Genetics. 2010 Jul 26 [Epub ahead of print].
Key words: environmental toxicology, protein folding, prefoldin complex, chemogenomics, arsenic, chaperonin, YKO
http://www.ncbi.nlm.nih.gov/pubmed/20660648

1. Cooper EM, Boeke JD, Cohen RE. Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin. J Biol Chem. 2010 Apr 2;285(14):10344-52.
Key words: BRISC, ubiquitin, deubiquitinating enzyme, JAMM/MPN+ domain, Lysine-63
http://www.jbc.org/content/285/14/10344.full
PMID: 20032457

2. Lee PA, Dymond JS, Scheifele LZ, Richardson SM, Foelber KJ, Boeke JD, Bader JS. CLONEQC: lightweight sequence verification for synthetic biology. Nucleic Acids Res. 2010 Mar 7;38(8):2617-23.
Key words: DNA synthesis, Quality control, sequence analysis
http://nar.oxfordjournals.org/cgi/content/full/38/8/2617
PMID: 2021184

3. Matecic M, Smith DL, Pan X, Maqani N, Bekiranov S, Boeke JD, Smith JS. A microarray-based genetic screen for yeast chronological aging factors. PLoS Genet. 2010 Apr 22;6(4):e1000921
Key words: CR functions, ADE genes and caloric restriction (CR)
http://www.plosgenetics.org/article/info:doi%2F10.1371%2Fjournal.pgen.1000921
PMID: 20421943

4. Richardson SM, Nunley PW, Yarrington RM, Boeke JD, Bader JS. GeneDesign 3.0 is an updated synthetic biology toolkit. Nucleic Acids Res. 2010 Mar 8;38(8):2603-6.
Key words: synthetic biology, synthetic genes, software, computer-assisted design
http://nar.oxfordjournals.org/cgi/content/full/38/8/2603
PMID: 20211837

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