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July 2008
PUBLICATIONS - Back

Biophysics and Biophysical Chemistry Archives

1. Huang CH, Mandelker D, Gabelli SB, Amzel LM. Insights into the oncogenic effects of /PIK3CA/ mutations from the structure of p110alpha/p85alpha. Cell Cycle. 2008 May;7(9):1151-6.
Key words: oncogene, PIK3CA, mutations
http://www.ncbi.nlm.nih.gov/pubmed/18418043?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

2. Mori MX, Vander Kooi CW, Leahy DJ, Yue DT. Crystal structure of the Ca(V)2 IQ domain in complex with Ca(2+)/calmodulin: high-resolution mechanistic implications for channel regulation by Ca(2+). Structure. 2008 Apr;16(4):607-20.
Key words: crystals, structures, calmodulin
http://www.ncbi.nlm.nih.gov/pubmed/18400181?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Bianchet MA, Erdemli SB, Amzel LM. Structure, function, and mechanism of cytosolic quinone reductases.Vitam Horm. 2008;78:63-84.
Key words: Cytosolic, Quinone, Reductases
http://www.ncbi.nlm.nih.gov/pubmed/18374190?ordinalpos=2&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

2. Leahy, D. A molecular view of anti-ErbB monoclonal antibody therapy. Cancer Cell. 2008 Apr;13(4):291-3.
Key words: Anti-ErbB, Antibody
http://www.ncbi.nlm.nih.gov/pubmed/18394550?ordinalpos=2&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

3. Qiu C, Tarrant MK, Choi SH, Sathyamurthy A, Bose R, Banjade S, Pal A, Bornmann WG, Lemmon MA, Cole PA, Leahy DJ. Mechanism of activation and inhibition of the HER4/ErbB4 kinase. Structure. 2008 Mar;16(3):460-7.
Key words: HER4, ErbB4, Kinase
http://www.ncbi.nlm.nih.gov/pubmed/18334220?ordinalpos=2&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

4. Suh Y, Atzmon G, Cho MO, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P. Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3438-42. Epub 2008 Mar 3.
Key words: Insulin, Centenarians
http://www.ncbi.nlm.nih.gov/pubmed/18316725?ordinalpos=2&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Qiu C, Lienhard S, Hynes NE, Badache A, Leahy DJ. Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site. J Biol Chem. 2008 Feb 1;283(5):2734-40. Epub 2007 Nov 28.
Key words: dioxygenases, ErbB2, phosphopeptide, peptides
http://www.ncbi.nlm.nih.gov/pubmed/18045866?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Qiu C, Lienhard S, Hynes NE, Badache A, Leahy DJ. Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site. J Biol Chem. 2008 Feb 1;283(5):2734-40. Epub 2007 Nov 28.
Key words: dioxygenases, ErbB2, phosphopeptide, peptides
http://www.ncbi.nlm.nih.gov/pubmed/18045866?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Acker MG, Kolitz SE, Mitchell SF, Nanda JS, Lorsch JR. Reconstitution of yeast translation initiation. Methods Enzymol. 2007;430:111-45.
Key words: Protein Synthesis, mechanism
http://www.ncbi.nlm.nih.gov/pubmed/17913637?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

2. Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF. NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science. 2008 Jan 25;319(5862):476-81.
Key words: NFAT, T cell, Homer
http://www.ncbi.nlm.nih.gov/pubmed/18218901?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

3. Xiao J, Elf J, Li G, Yu J, Xie XS, Imaging gene expression in living cells at the single molecule level. Single Molecules: A Laboratory Manual, edited by Selvin P., and Ta H. Dec. 2007, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Key words: Imaging, single molecules

1. Dohán O, Portulano C, Basquin C, Reyna-Neyra A, Amzel LM, Carrasco N. The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20250-5.
Key words: plasma membrane protein, perchlorate, pollutants
http://www.ncbi.nlm.nih.gov/pubmed/18077370?ordinalpos=4&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

2. Huang CH, Mandelker D, Schmidt-Kittler O, Samuels Y, Velculescu VE, Kinzler KW, Vogelstein B, Gabelli SB, Amzel LM. The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science. 2007 Dec14; 318(5857):
1744-8.
Key words: p110alpha/p85alpha; oncogene, mutations, P13Kalpha
http://www.ncbi.nlm.nih.gov/pubmed/18079394?ordinalpos=4&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

3. Leahy DJ. A monkey wrench in the kinase machine. Nat Struct Mol Biol. 2007 Dec;14(12):1120-1.
Key words: kinase,
http://www.ncbi.nlm.nih.gov/pubmed/18059449?ordinalpos=4&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

4. Qiu C, Lienhard S, Hynes NE, Badache A, Leahy DJ. Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site. J Biol Chem. 2007 Nov 28; [Epub ahead of print]
Key words: iron dioxygenase, ErbB2, phosphopeptide
http://www.ncbi.nlm.nih.gov/pubmed/18045866?ordinalpos=4&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

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July 2008 articles:
JHM Human Subjects Research Program Reaccredited
 
Seminar Series
Explore Funding Opportunities from The Maryland Stem Cell Research Fund
BCRF-AACR Grants for Translational Breast Cancer Research
Susan G. Komen for the Cure-AACR Outstanding Investigator Award for Breast Cancer Research
W.W. Smith Charitable Trust - Heart Research Grants for 2009
Beckman Young Investigator Program for 2009
Biomedical Scholars Programs
RWJ Physician Faculty Scholars Program
Progeria Research Foundation Seeks Proposals for Research on Hutchinson-Gilford Progeria Syndrome (Progeria) and Progeroid Laminopathies
The Fondation Leducq 2008-2009 Transatlantic Networks of Excellence in Cardiovascular Research Program
PhRMA Foundation 2009 Awards in Pharmacology
PhRMA Foundation 2009 Awards in Informatics
 

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