Web notes  

February 2017
PUBLICATIONS - Back

Biophysics and Biophysical Chemistry Archives

1. Thomsen ND, Lawson MR, Witkowsky LB, Qu S, Berger JM. Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7691-E7700.
Key words: Transcription, Helicase, ATPase, Motor Protein, translocase
https://www.ncbi.nlm.nih.gov/pubmed/27856760

2. Lawson MR, Dyer K, Berger JM. Ligand-induced and small-molecule control of substrate loading in a hexameric helicase. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13714-13719.
Key words: Transcription, Helicase, ATPase, Drug Discovery, Motor Protein
https://www.ncbi.nlm.nih.gov/pubmed/27821776

1. Yu A, Alberstein R, Thomas A, Zimmet A, Grey R, Mayer ML, Lau AY. Molecular lock regulates binding of glycine to a primitive NMDA receptor. Proc Natl Acad Sci USA. 2016 Nov 1;113(44):E6786-E6795.
Key words: X-ray crystallography; electrophysiology; free energy calculations; glutamate receptors; molecular dynamics simulations
https://www.ncbi.nlm.nih.gov/pubmed/27791085

1. Bleichert F, Botchan MR, Berger JM. Crystal structure of the eukaryotic origin recognition complex. Nature. 2015 519:321-6.
Key words: DNA replication, Helicase, MCM, CMG, ORC, clamp loader, AAA+ ATPase
http://www.ncbi.nlm.nih.gov/pubmed/25762138

1. Gabelli SB, Boto A, Kuhns VH, Bianchet MA, Farinelli F, Aripirala S, Yoder J, Jakoncic J, Tomaselli GF, Amzel LM. Regulation of the NaV1.5 cytoplasmic domain by calmodulin. Nat Commun. 2014 Nov 5;5:5126. doi: 10.1038/ncomms6126.
Key words: cytoplasm, calmodulin
http://www.ncbi.nlm.nih.gov/pubmed/25370050

1. Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3K?. Oncotarget. 2014 Jul 30;5(14):5198-208.

1. Vos SM, Lyubimov AY, Hershey DM, Schoeffler AJ, Sengupta S, Nagaraja V, Berger JM. Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein. Genes Dev. 2014 Jul 1;28(13):1485-97
Key words: Topoisomerase, Enzyme inhibitors, Antibiotics, Gene Regulation, Transcription, Supercoiling, Energy metabolism
http://www.ncbi.nlm.nih.gov/pubmed/24990966

2. Nicola J, Carrasco N, Amzel LM. Physiological sodium concentrations enhance the iodide affinity of the Naþ/I_ symporter. Nature Communications. 2014 June 3. doi:10.1038/ncomms4948
Key words: sodium, iodide
No PMID available

1. Berndsen CE, Wolberger C. New insights into ubiquitin E3 ligase mechanism. Nat Struct Mol Biol. 2014 Apr 4;21(4):301-7. doi: 10.1038/nsmb.2780.
Key words: ubiquitin, E3 ligase, E2 enzyme
http://www.ncbi.nlm.nih.gov/pubmed/24699078

2. Wolberger C. Mechanisms for regulating deubiquitinating enzymes. Protein Sci. 2014 Apr;23(4):344-53. doi: 10.1002/pro.2415.
Key words: deubiquitinating enzymes; UB, UBL, ubiquitin
http://www.ncbi.nlm.nih.gov/pubmed/24403057

1. Harden BJ, Frueh DP. SARA: a software environment for the analysis of relaxation data acquired with accordion spectroscopy. J Biomol NMR. 2014 Feb;58(2):83-99.
Key words: software, accordion spectroscopy
http://www.ncbi.nlm.nih.gov/pubmed/24408364

2. Frueh DP. Practical aspects of NMR signal assignment in larger and challenging proteins. Prog Nucl Magn Reson Spectrosc. 2014 Apr;78C:47-75.
Key words: NMR, proteins
http://www.ncbi.nlm.nih.gov/pubmed/24534088

3. Mustaev A, Malik M, Zhao X, Kurepina N, Luan G, Oppegard LM, Hiasa H, Marks KR, Kerns RJ, Berger JM, Drlica K. Fluoroquinolone-Gyrase-DNA complexes: two modes of drug binding. J Biol Chem. 2014 Feb 4 [Epub ahead of print].
Key words: Antibiotics action, Bacteria, DNA topoisomerase, Enzyme inhibitors, Escherichia coli, Mycobacterium smegmatis, bacterium, cleaved complexes, crosslinking, resistance mutations
http://www.ncbi.nlm.nih.gov/pubmed/24497635

4. Strycharska MS, Arias-Palomo E, Lyubimov AY, Erzberger JP, O'Shea VL, Bustamante CJ, Berger JM. Nucleotide and partner-protein control of bacterial replicative helicase structure and function. Mol Cell. 2013 Dec 26;52(6):844-54.
Key words: DNA replication, Helicase, Primase, Clamp Loader, AAA+ ATPase, RecA
http://www.ncbi.nlm.nih.gov/pubmed/24373746

Return to top of Publications - Biophysics and Biophysical Chemistry Archives

Search Publications
 
   
February 2017 articles:
Third Thursdays with the ICTR
Funding Opportunity: Accelerated Translational Incubator Pilot Program (ATIP) Grant
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
JHM HSR Recertification Training
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
2017 NASA Space Radiation Summer School
Young Investigator Grant for Probiotics Research (YIGPRO)
Bay Area Lyme Foundation Emerging Leader Award
DHHS - Partnerships to Achieve Health Equity
Society for Vascular Surgery Foundation Clinical Research Seed Grant Program
Progeria Research Foundation Grants
NIH - Shared Instrumentation for Animal Research (SIFAR) Grant Program (S10)
NIH - Shared Instrumentation for Animal Research (SIFAR) Grant Program (S10)
Michael J. Fox Foundation (MJFF) Challenge
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for February, March and April

February Events at the Genetic Resources Core Facility
       

 


 

JHM AppointmentsEmployment @ JHM | Finding a Doctor | Disclaimer | Maps & Directions | Contact JHM 

 

                                                                                                                                                           The Web Center