Web notes  

September 2016
PUBLICATIONS - Back

Biophysics and Biophysical Chemistry Archives

1. Bleichert F, Botchan MR, Berger JM. Crystal structure of the eukaryotic origin recognition complex. Nature. 2015 519:321-6.
Key words: DNA replication, Helicase, MCM, CMG, ORC, clamp loader, AAA+ ATPase
http://www.ncbi.nlm.nih.gov/pubmed/25762138

1. Gabelli SB, Boto A, Kuhns VH, Bianchet MA, Farinelli F, Aripirala S, Yoder J, Jakoncic J, Tomaselli GF, Amzel LM. Regulation of the NaV1.5 cytoplasmic domain by calmodulin. Nat Commun. 2014 Nov 5;5:5126. doi: 10.1038/ncomms6126.
Key words: cytoplasm, calmodulin
http://www.ncbi.nlm.nih.gov/pubmed/25370050

1. Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3K?. Oncotarget. 2014 Jul 30;5(14):5198-208.

1. Vos SM, Lyubimov AY, Hershey DM, Schoeffler AJ, Sengupta S, Nagaraja V, Berger JM. Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein. Genes Dev. 2014 Jul 1;28(13):1485-97
Key words: Topoisomerase, Enzyme inhibitors, Antibiotics, Gene Regulation, Transcription, Supercoiling, Energy metabolism
http://www.ncbi.nlm.nih.gov/pubmed/24990966

2. Nicola J, Carrasco N, Amzel LM. Physiological sodium concentrations enhance the iodide affinity of the Naþ/I_ symporter. Nature Communications. 2014 June 3. doi:10.1038/ncomms4948
Key words: sodium, iodide
No PMID available

1. Berndsen CE, Wolberger C. New insights into ubiquitin E3 ligase mechanism. Nat Struct Mol Biol. 2014 Apr 4;21(4):301-7. doi: 10.1038/nsmb.2780.
Key words: ubiquitin, E3 ligase, E2 enzyme
http://www.ncbi.nlm.nih.gov/pubmed/24699078

2. Wolberger C. Mechanisms for regulating deubiquitinating enzymes. Protein Sci. 2014 Apr;23(4):344-53. doi: 10.1002/pro.2415.
Key words: deubiquitinating enzymes; UB, UBL, ubiquitin
http://www.ncbi.nlm.nih.gov/pubmed/24403057

1. Harden BJ, Frueh DP. SARA: a software environment for the analysis of relaxation data acquired with accordion spectroscopy. J Biomol NMR. 2014 Feb;58(2):83-99.
Key words: software, accordion spectroscopy
http://www.ncbi.nlm.nih.gov/pubmed/24408364

2. Frueh DP. Practical aspects of NMR signal assignment in larger and challenging proteins. Prog Nucl Magn Reson Spectrosc. 2014 Apr;78C:47-75.
Key words: NMR, proteins
http://www.ncbi.nlm.nih.gov/pubmed/24534088

3. Mustaev A, Malik M, Zhao X, Kurepina N, Luan G, Oppegard LM, Hiasa H, Marks KR, Kerns RJ, Berger JM, Drlica K. Fluoroquinolone-Gyrase-DNA complexes: two modes of drug binding. J Biol Chem. 2014 Feb 4 [Epub ahead of print].
Key words: Antibiotics action, Bacteria, DNA topoisomerase, Enzyme inhibitors, Escherichia coli, Mycobacterium smegmatis, bacterium, cleaved complexes, crosslinking, resistance mutations
http://www.ncbi.nlm.nih.gov/pubmed/24497635

4. Strycharska MS, Arias-Palomo E, Lyubimov AY, Erzberger JP, O'Shea VL, Bustamante CJ, Berger JM. Nucleotide and partner-protein control of bacterial replicative helicase structure and function. Mol Cell. 2013 Dec 26;52(6):844-54.
Key words: DNA replication, Helicase, Primase, Clamp Loader, AAA+ ATPase, RecA
http://www.ncbi.nlm.nih.gov/pubmed/24373746

1. Bleichert F, Balasov M, Chesnokov I, Nogales E, Botchan MR, Berger JM. A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation. Elife. 2013 Oct 8;2:e00882.
Key words: DNA replication, Meier-Gorlin syndrome, ORC, origin licensing, origin recognition complex, MCM
http://elife.elifesciences.org/content/2/e00882
PMID: 24137536

2. Vos SM, Lee I, Berger JM. Distinct regions of the Escherichia coli ParC C-terminal domain are required for substrate discrimination by topoisomerase IV. J Mol Biol. 2013 Sep 9;425(17):3029-45.
Key words: DNA topology, topoisomerase, DNA binding
http://www.sciencedirect.com/science/article/pii/S0022283613004208
PMID: 23867279

3. Vos SM, Stewart NK, Oakley MG, Berger JM. Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo. EMBO J. 2013 Oct 4. doi:
10.1038/emboj.2013.218. [Epub ahead of print]
Key words: DNA topology, topoisomerase, chromosome segregation, chromosome partitioning, SMC, condensin, cohesin
http://www.nature.com/emboj/journal/vaop/ncurrent/full/emboj2013218a.html
PMID:24097060

1. Wiener R, Dibello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C.
E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat Struct Mol Biol. 2013 Sep;20(9):1033-9. doi: 10.1038/nsmb.2655.
Key words: ubiquitin, enzymes, OTUB1
http://www.nature.com/nsmb/journal/v20/n9/full/nsmb.2655.html
PMID: 23955022

2. Yao Y, Belcher J, Berger AJ, Mayer ML, Lau AY. Conformational analysis of NMDA receptor GluN1, GluN2, and GluN3 ligand-binding domains reveals subtype-specific characteristics. Structure. 2013 Oct 8; 21(10):1788-1799.
Key words: Glutamate receptor, NMDA, Computational modeling, X-ray crystallography
http://www.ncbi.nlm.nih.gov/pubmed/23972471

1. Wiener R, Dibello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C. E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat Struct Mol Biol. 2013 Sep;20(9):1033-9. doi: 10.1038/nsmb.2655.
Key words: ubiquitin, e2, deubiquitinating enzymes
http://www.nature.com/nsmb/journal/v20/n9/full/nsmb.2655.html
PMID: 23955022

Return to top of Publications - Biophysics and Biophysical Chemistry Archives

Search Publications
 
   
September 2016 articles:
Henrietta Lacks Memorial Lecture
Johns Hopkins Institute for Clinical and Translational Research
Johns Hopkins Research Network
JHM HSR Recertification Training
 
Visit Animal Care and Use Committee Website
Current Classes
"Interinstitutional Assurance" Agreement
Health, Safety, and Environment (HSE) presents: Safety in Research Updates
7th Annual Mirowski Discovery Award
Department of Defense Prostate Cancer Research Program (PCRP)
2016 Martin D. Abeloff Award for Excellence in Public Health and Cancer Control
The Sherrilyn and Ken Fisher Center for Environmental Infectious Diseases Discovery Program
2017 Arnold O. Beckman Postdoctoral Fellowship for Life Sciences Research
Progeria Research Foundation Seeks Proposals for Research on Hutchinson-Gilford Progeria Syndrome (HGPS, or Progeria)
Burroughs Wellcome Fund - Career Awards for Medical Scientists
Bright Focus Foundation Alzheimer's Disease Research Grants
Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation Grant Program
Bright Focus Foundation National Glaucoma Research Grants
Milstein Medical Asian American Partnership Foundation Fellowship and Project Awards
Michael J. Fox Foundation (MJFF) Challenge
Research Administration Training Program for Existing Staff (RPES)
NIH Policy: Foreign Components Added to a Grant to a Domestic or Foreign Organization

This Month's Departmental Listings

Upcoming Deadlines for September, October and November

The JHU SOM Core Showcase
September Events at the Genetic Resources Core Facility
       

 


 

JHM AppointmentsEmployment @ JHM | Finding a Doctor | Disclaimer | Maps & Directions | Contact JHM 

 

                                                                                                                                                           The Web Center