September 2014
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Biological Chemistry Archives

1. Fukunaga R, Zamore PD. A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis. Cell Cycle. 2014 Jun 1;13(11):1671-6.
Key words: siRNA, miRNA, phosphate, Dicer
http://www.ncbi.nlm.nih.gov/pubmed/24787225

2. Majkowska-Skrobek G, Augustyniak D, Lis P, Bartkowiak A, Gonchar M, Ko YH, Pedersen PL, Goffeau A, Ulaszewski S. Killing multiple myeloma cells with the small molecule 3-bromopyruvate: implications for therapy. Anticancer Drugs. 2014 Jul;25(6):673-82.
Key words: cancer, multiple myeloma, Warburg effect, 3-bromopyruvate, anti-cancer drugs
http://www.ncbi.nlm.nih.gov/pubmed/2455701

1. Reeves RA, Lee A, Henry R, Zachara NE. Characterization of the specificity of O-GlcNAc reactive antibodies under conditions of starvation and stress. Anal Biochem. 2014 Apr 18;457C:8-18.[Epub ahead of print]
Key words: O-GlcNAc, Signaling, Antibodies, Chitobiose, Stress
http://www.ncbi.nlm.nih.gov/pubmed/24747005

1. Heydarian M, Luperchio TR, Cutler J, Mitchell CJ, Kim MS, Pandey A, Sollner-Webb B, Reddy KL. Prediction of gene activity in early B cell development based on an integrative multi-omics analysis. J Proteomics Bioinform. 2014;7: 050-063. doi: 10.4172/jpb.1000302
Key words: RNA-seq. iTRAQ, B cell development, chromatin, proteome, transcriptome
No PMID available

2. Luperchio TR, Wong X, Reddy KL. Genome regulation at the peripheral zone: lamina associated domains in development and disease. Curr Opin Genet Dev. 2014 Feb 17;25C:50-61.
Key words: nuclear architecture, genome organization, chromatin, gene regulation, nuclear lamina
http://www.ncbi.nlm.nih.gov/pubmed/24556270

3. Watkin EE, Arbez N, Waldron-Roby E, O'Meally R, Ratovitski T, Cole RN and Ross CA. Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity. PLoS ONE. 2014 Feb 5;9(2):e88284.
Key words: Huntington's Disease; N-terminal Htt; therapeutic targets
http://www.ncbi.nlm.nih.gov/pubmed/24505464

1. Fukunaga R, Colpan C, Han BW, Zamore PD. Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain. EMBO J. 2014 Feb 18;33(4):371-84. doi: 10.1002/embj.201387176.
Key words: miRNA, siRNA, Dicer, phosphate, PAZ
http://www.ncbi.nlm.nih.gov/pubmed/24488111

2. Kim YS, Chu Y, Han L, Li M, Li Z, Lavinka PC, Sun S, Tang Z, Park K, , MJ, Ren K, Dubner R, Wei F, Dong X. Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain. Neuron. 2014;81:873-87.
Key words: nociception, optogenetics, calcium, chronic pain
http://www.ncbi.nlm.nih.gov/pubmed/24462040

3. Majkowska-Skrobek G, Augustyniak D, Lis P, Bartkowiak A, Gonchar M, Ko YH, Pedersen PL, Goffeau A, Ulaszewski S. Killing multiple myeloma cells with the small molecule 3-bromopyruvate: implications for therapy. Anticancer Drugs. 2014 Feb 19 [Epub ahead of print].
Key words: cancer, multiple myeloma, 3-bromopyruvate, therapy
http://www.ncbi.nlm.nih.gov/pubmed/24557015

4. Meier EL, Goley ED. Form and function of the bacterial cytokinetic ring. Curr Opin Cell Biol. 2014 Feb; 26:19-27.
Key words: cytokinesis, FtsZ, super-resolution imaging, biomimetic systems
http://www.ncbi.nlm.nih.gov/pubmed/24529242

1. Fukunaga R, Colpan C, Han BW, Zamore PD. Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain. EMBO J. 2014 Feb 18;33(4):371-84.
Key words: miRNA, siRNA, Dicer, phosphate, PAZ
http://www.ncbi.nlm.nih.gov/pubmed/24488111

2. Tardio L, Andrés-Bergós J, Zachara NE, Larrañaga-Vera A, Rodriguez-Villar C, Herrero-Beaumont G, Largo R.O-linked N-acetylglucosamine (O-GlcNAc) protein modification is increased in the cartilage of patients with knee osteoarthritis.Osteoarthritis Cartilage. 2014 Feb;22(2):259-63.
Key words: Intracellular Glycosylation, Signaling, Osteoarthritis, Inflammation
http://www.ncbi.nlm.nih.gov/pubmed/24333294

3. Zhang Y, Dayalan Naidu S, Samarasinghe K, Van Hecke GC, Pheely A, Boronina TN, Cole RN, Benjamin IJ, Cole PA, Ahn YH and Dinkova-Kostova AT. Sulphoxythiocarbamates modify cysteine residues in hsp90 causing degradation of client proteins and inhibition of cancer cell proliferation. Br J Cancer. 2014 Jan 7;110(1):71-82
Key words: Hsp90; NRF2; cysteine; HSF1
http://www.ncbi.nlm.nih.gov/pubmed/24322890

1. Caterina MJ. Boosting that tan with a bit of voltage. Channels (Austin). 2013 Oct 2;7(6), 1.
Key words: channel, ultraviolet, TRPA1, melanin, melanocyte
http://www.ncbi.nlm.nih.gov/pubmed/24088950

2. Cole RN, Ruczinski I, Schulze K, Christian P, Herbrich S, Wu L, Devine LR, O'Meally RN, Shrestha S, Boronina TN, Yager JD, Groopman J and West KP, Jr. The plasma proteome identifies expected and novel proteins correlated with micronutrient status in undernourished nepalese children. Journal of Nutrition. 2013 Oct; 143(10):1540-8.
Key words: Quantitative proteomics, nutrition, protein proxies
http://www.ncbi.nlm.nih.gov/pubmed/23966331

3. Zhang Y, Dayalan Naidu S, Samarasinghe K, Van Hecke GC, Pheely A, Boronina TN, Cole RN, Benjamin IJ, Cole PA, Ahn YH and Dinkova-Kostova AT. Sulphoxythiocarbamates modify cysteine residues in hsp90 causing degradation of client proteins and inhibition of cancer cell proliferation. Br J Cancer. 2013 Dec 5. doi: 10.1038/bjc.2013.710.
Key words: Hsp90; NRF2; cysteine; HSF1
http://www.ncbi.nlm.nih.gov/pubmed/24322890

1. Mihalas AB, Araki Y, Huganir RL, Meffert MK. Opposing action of nuclear factor kB and polo-like kinases determines a homeostatic end point for excitatory synaptic adaptation. J. Neurosci. 2013 Oct 16; 33(42):16490-501.
Key words: Synaptic plasticity, nuclear factor kappaB, homeostatic plasticity, hippocampus, gene expression
http://www.ncbi.nlm.nih.gov/pubmed/24133254

1. Ueda S, Tu-Sekine B, Yamanoue M, Raben DM, Shirai Y. The expression of diacylglycerol kinase theta during the organogenesis of mouse embryos. BMC Dev Biol. 2013 Oct 1;13(1):35.
Key words: Diacylglycerol kinase, development, mice
http://www.ncbi.nlm.nih.gov/pubmed/24079595

1. Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN and O'Rourke B. The cardiac acetyl-lysine proteome. PLoS One. 2013 13 Jul 2;8(7):e67513.
Key words: cardiovascular disease, post-translational modifications, mass spectrometry
http://www.ncbi.nlm.nih.gov/pubmed/23844019

2. Kunjithapatham R, Geschwind JF, Rao PP, Boronina TN, Cole RN and Ganapathy-Kanniappan S. Systemic administration of 3-bromopyruvate reveals its interaction with serum proteins in a rat model. BMC Res Notes. 2013 Jul 17;6(1):277.
Key words: alpha1 antitrypsin, chemical adduct modification, 2D gel electrophoresis, mass spectrometry
http://www.ncbi.nlm.nih.gov/pubmed/2386682

1. Coulombe PA, Caterina MJ. The incidental pore: CaV1.2 and stem cell activation in quiescent hair follicles. Genes Dev. 2013 Jun 15;27(12):1315-7.
Key words: stem cell, hair follicle, calcium channel, channelopathy, Timothy Syndrome
http://genesdev.cshlp.org/content/27/12/1315.long
PMID: 23788620

2. Ruiz CR, Shi J, Meffert MK. Transcript specificity in BDNF-regulated protein synthesis. Neuropharmacology. 2013 May 22. doi:pii: S0028-3908(13)00213-X. 10.1016/j.neuropharm.2013.05.004. [Epub ahead of print]
Key words: BDNF, translation, microRNA, Lin28
http://www.ncbi.nlm.nih.gov/pubmed/?term=23707639

1. Dumbauld DW, Lee TT, Singh A, Scrimgeour J, Gersbach CA, Zamir EA, Fu J, Chen CS, Curtis JE, Craig SW, García AJ. How vinculin regulates force transmission. Proc. Nat'l Acad. Sci. U.S.A. 2013; 2013 Jun 11;110(24):9788-93.
Key words: vinculin, mechanotransduction, cell adhesion, talin, focal adhesions
http://www.ncbi.nlm.nih.gov/pubmed/23716647

2. Dyl?g M, Lis P, Nied?wiecka K, Ko YH, Pedersen PL, Goffeau A, U?aszewski S. 3-Bromopyruvate: A novel antifungal agent against the human pathogen Cryptococcus neoformans. Biochem Biophys Res Commun. 2013 May 3;434(2):322-7.
Key words: 3-bromopyruvateante, antifungal, pathogens
http://www.ncbi.nlm.nih.gov/pubmed/23541578

3. Ruiz CR, Shi J, Meffert MK. Transcript specificity in BDNF-regulated protein synthesis. Neuropharmacology. 2013 May 22. pii: S0028-3908(13)00213-X. doi: 10.1016/j.neuropharm.2013.05.004. [Epub ahead of print]
Key words: microRNA biogenesis, Translation, protein synthesis, neurotrophin, plasticity
http://www.ncbi.nlm.nih.gov/pubmed/23707639

1. Dylag M, Lis P, Niedzwiecka K, Ko YH, Pedersen PL, Goffeau A, Utaszewski S. 3-Bromopyruvate: A novel antifungal agent against the human pathogen Cryptococcus neoformans. Biochem Biophys Res Commun. 2013 May 3;434(2):322-7.
Key words: fungal infections, Cryptococcus neoformans, 3-bromopyruvate, anti-fungal
http://www.ncbi.nlm.nih.gov/pubmed/23541578

2. Goley ED. Tiny cells meet big questions: a closer look at bacterial cell biology. Mol Biol Cell. 2013 Apr; 24(8):1099-102.
Key words: bacterial cell biology, cytoskeleton, endomembranes
http://www.ncbi.nlm.nih.gov/pubmed/23580191

3. Groves JA, Lee A, Yildirir G, Zachara NE. Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis. Cell Stress Chaperones. 2013 Apr 26. [Epub ahead of print]
Key words: O-GlcNAc, Glycosylation, Heat Shock Protein, Stress Response, Signaling
http://www.ncbi.nlm.nih.gov/pubmed/23620203

1. Ellis JM, Wong GW, Wolfgang MJ. Acyl Coenzyme A Thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity. Mol Cell Biol. 2013 May; 33(9) 1869-1882.
Key words: lipid, brain, neurodegeneration, biochemistry, knockout
http://mcb.asm.org/content/33/9/1869.full
PMID: 23459938

1. Chan, W, Schaeffer TB, Pomerantz JL. A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol. 2013 Jan; 33(2):429-443.
Key words: lymphoma, signaling, NF-kappaB, CARD11, Bcl10
http://www.ncbi.nlm.nih.gov/pubmed/23149938

1. Chan, W, Schaeffer TB, Pomerantz JL A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol. 2013 Jan; 33(2):429-443.
Key words: lymphoma, signaling, NF-kappaB, CARD11, Bcl10
http://www.ncbi.nlm.nih.gov/pubmed/23149938

2. Jensen RV, Johnsen J, Kristiansen SB, Zachara NE, Bøtker HE. Ischemic preconditioning increases myocardial O-GlcNAc glycosylation. Scand Cardiovasc J. 2013; EPUB Jan 10.
Key words: Cardioprotection, Intracellular Glycosylation, O-GlcNAc, Signaling
http://www.ncbi.nlm.nih.gov/pubmed/23301939

3. Jensen RV, Zachara NE, Nielsen PH, Kimose HH, Kristiansen SB, Bøtker HE. Impact of O'GlyNAc on cardioprotection by remote ischaemic preconditioning in non-diabetic and diabetic patients. Cardiovasc Res. 2013; 97(2):369-78
Key words: Cardioprotection, Intracellular Glycosylation, O-GlcNAc, Signaling
http://www.ncbi.nlm.nih.gov/pubmed/23201773

4. Ramel D, Wang X, Laflamme C, Montell DJ, Emery G. Rab11 regulates cell-cell communication during collective cell movements. Nat Cell Biol. 2013 Feb 3. doi: 10.1038/ncb2681. [Epub ahead of print]
Key words: Rab11, collective cell migration, moesin, cell-cell communication, Drosophila
http://www.ncbi.nlm.nih.gov/pubmed/23376974

1. Chan, W, Schaeffer TB, Pomerantz JL. A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol. 2013. 33(2):429-443.
Key words: lymphoma, signaling, NF-kappaB, CARD11, Bcl10
http://www.ncbi.nlm.nih.gov/pubmed/23149938

2. Coyer SR, Singh A, Dumbauld DW, Calderwood DA, Craig SW, Delamarche E, Garcia AJ. Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeletal tension. J of Cell Sci. 2012; 25:5110-5123. Epub 2012 Aug 16.
Key words: Cell-adhesion, Fibronectin, Vinculin, Talin, Focal adhesion
http://www.ncbi.nlm.nih.gov/pubmed/22899715

3. Pedersen PL. Mitochondria in relation to cancer metastasis: introduction to a mini-review series. J Bioenerg Biomembr 2012 Dec 44(6):615-7.
Key words: cancer, metastasis, "Warburg", 3-brompyruvate, hexokinase 2
http://www.ncbi.nlm.nih.gov/pubmed/22926290

4. Tu-Sekine B, Raben DMJ. Dual regulation of diacylglycerol kinase (DGK)-?: polybasic proteins promote activation by phospholipids and increase substrate affinity. Biol. Chem. 2012;287:41619-41627.
Key words: Diacylglycerol kinase, Interfacial Enzymology, Enzyme Regulation, Polybasic Proteins
http://www.ncbi.nlm.nih.gov/pubmed/23091060

1. Pedersen PL. Mitochondria in relation to cancer metastasis: introduction to a mini-review series. J Bioenerg Biomembr. 2012 Dec;44(6):615-7.
Key words: cancer, metastasis, 3-bromopyruvate (3BP), anticancer drug
http://www.ncbi.nlm.nih.gov/pubmed/22926290

2. Jensen RV, Zachara NE, Nielsen PH, Kimose HH, Kristiansen SB, Bøtker HE. Impact of O-GlcNAc on cardioprotection by remote ischaemic preconditioning in non-diabetic and diabetic patients. Cardiovasc Res. 2012 Dec 1. [Epub ahead of print]
Key words: O-GlcNAc, Cardioprotection, Remote Ischemic Preconditioning, Cellular Stress
http://www.ncbi.nlm.nih.gov/pubmed/23201773

1. Ellis JM, Wolfgang MJ. A genetically encoded metabolite sensor for malonlyl-CoA. Chem Biol. 2012 Oct 26;19(10):1333-9.
Key words: malonyl-CoA, biosensor, fatty acid, ampk, malonyl-CoA decarboxylase
http://www.sciencedirect.com/science/article/pii/S1074552112003298
PMID: 23102226

2. Fowler MA, Montell C. Drosophila TRP channels and animal behavior. Life Sci. 2012 Aug 1 [Epub ahead of print].
Key words: drosophima, TRP, animal behavior
http://www.ncbi.nlm.nih.gov/pubmed/22877650

3. Guo Q, Wang X, Tibbitt MW, Anseth KS, Montell DJ, Elisseeff JH. Light activated cell migration in synthetic extracellular matrices. Biomaterials. 2012 Nov;33(32):8040-6. doi: 10.1016/j.biomaterials.2012.07.013.
Key words: cell migration, extracellular matrices
http://www.ncbi.nlm.nih.gov/pubmed/22889487

4. He L, Montell D. A cellular sense of touch. Nat Cell Biol. 2012 Sep;14(9):902-3. doi: 10.1038/ncb2572.
Key words: cellular, touch
http://www.ncbi.nlm.nih.gov/pubmed/2945256

5. Lee J, Wolfgang MJ. Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism. BMC Biochem. 2012 Oct 25;13(1):23.
Key words: Fatty acid, carnitine palmitoyltransferase 1, knockout, brain, metabolism
http://www.biomedcentral.com/1471-2091/13/23/abstract
PMID: 23098614

6. Montell CDJ, Yoon WH, Starz-Gaiano M. Group choreography mechanisms orchestrating the collective movement of border cells. Nat Rev Mol Cell Biol. 2012 Oct;13(10):631-45. Doi: 1038/nm3433.
Key words: border cells, movement, choreography mechanisms
http://www.ncbi.nlm.nih.gov/pubmed/23000794

7. Venkatachalam K, Wong CO, Montell C. Feast or Famine: Role of TRPML in preventing cellular amino acid starvation. Autophagy. 2012 Oct 9;9(1). [Epub ahead of print]
Key words: cellular amino acid starvation, TRPML
http://www.ncbi.nlm.nih.gov/pubmed/23147439

8. Wong CO, Li R, Montell C, Venkatachalam K. Drosophila TRPML is required for TORC1 activation. Curr. Biol. 2012 Sep11;22(17):1616-21.
http://www.ncbi.nlm.nih.gov/pubmed/2283314

1. Fowler MA, Montell C. Drosophila TRP channels and animal behavior. Life Sci. 2012 Aug 1. [Epub ahead of print]
Key words: TRP channels, Drosophila, behavior, sensory signaling, thermosensation, taste, smell, vision, mechanosensation, phospholipase C, gustatory, olfactory, phototransduction, calcium, proprioception
http://www.ncbi.nlm.nih.gov/pubmed/22877650

2. He L, Montell D. A cellular sense of touch. Nat Cell Biol. 2012 Sep 3;14(9):902-3. doi: 10.1038/ncb2572.
Key words: Drosophila melanogaster, cell adhesion, cell migration, cell motility, cell polarity, review
http://www.ncbi.nlm.nih.gov/pubmed/22945256

3. Montell DJ, Yoon WH, Starz-Gaiano M. Group choreography: mechanismsorchestrating the collective movement of border cells. Nat Rev Mol Cell Biol. 2012 Oct;13(10):631-45. doi: 10.1038/nrm3433.
Key words: Drosophila melanogaster, cell adhesion, mechanotransduction
http://www.ncbi.nlm.nih.gov/pubmed/23000794

4. Nedungadi TP, Dutta M, Bathina CS, Caterina MJ, Cunningham JT. Expression and distribution of TRPV2 in rat brain. Exp Neurol. 2012;237:223-37
Key words: Transient receptor potential, ion channel, vanilloid, osmoregulation
http://www.sciencedirect.com/science/article/pii/S0014488612002592
PMID: 22750329

5. Wong CO, Li R, Montell C, Venkatachalam K. Drosophila TRPML Is Required for TORC1 Activation. Curr Biol. 2012 Sep 11;22(17):1616-21. Epub 2012 Aug 2.
Key words: Drosophila, TORC1 activation
http://www.ncbi.nlm.nih.gov/pubmed/22863314

1. Fowler MA, Montell C. Drosophila TRP channels and animal behavior. Life Sci. 2012 Aug 1 [Epub ahead of print].
Key words: TRP, transient receptor channel, cell surface receptors, behaviors, disease
http://www.ncbi.nlm.nih.gov/pubmed/22877650

2. He L, Montell D. A cellular sense of touch. Nat. Cell Biol. 2012 Sep3;14(9):902-3.
Key words: Drosophila, integrin, integrin adhesion in vivo
http://www.ncbi.nlm.nih.gov/pubmed/22945256

3. Wong CO, Li R, Montell C, Venkatachalam K. Drosophila TRPML is required for TORC1 activation. Curr. Biol. 2012 Sep11;22(17):1616-21.
Key words: TRPML and TORC1 pathways, loss of function mutations, lysosomal storage disorder,diet, MLIV
http://www.ncbi.nlm.nih.gov/pubmed/22863314

1. Tang HL, Tang HM, Mak KH, Hu S, Wang SS, Wong K, Wong CST, Wu HY, Law HT, Liu K, Talbot Jr CC, Lau WK, Montell DJ, Fung MC. DNA damage and oncogenic transformation following a transient and reversible apoptopic response. Mol Biol Cell. 2012 Jun;23(12):2240-52.
Key words: DNA, apoptosis, oncogenic transformation
http://www.ncbi.nlm.nih.gov/pubmed/22535522

1. Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh HS. DNA Sequence-Dependent Compartmentalization and silencing of chromatin at the nuclear lamina. Cell. 2012 Jun 22;149(7):1474-87.
Key words: nulcear lamina, GAGA sequences, cKrox/ThPOK/ZBTB7B, HDAC3, Lap2?
http://www.sciencedirect.com/science/article/pii/S0092867412005910
DOI 10.1016/j.cell.2012.04.03
PMID: 22726435

1. Miyamoto T, Derose R, Suarez A, Ueno T, Chen M, Sun TP, Wolfgang MJ, Mukherjee C, Meyers DJ, Inoue T. Rapid and orthogonal logic gating with a gibberellin-induced dimerization system. Nat Chem Biol. 2012 Mar 25;8(5):465-70.
Key words: gibberellin, dimerization
http://www.nature.com/nchembio/journal/v8/n5/full/nchembio.922.html
PMID: 22446836

2. Rodriguez S, Wolfgang MJ. Targeted chemical-genetic regulation of protein stability in vivo. Chem Biol. 2012 Mar 23;19(3):391-8.
Key words: malonyl-CoA Decarboxylase, fatty acid, metabolism
http://www.sciencedirect.com/science/article/pii/S1074552112000506
PMID: 22444594

3. Wei Z, Peterson JM, Lei X, Cebotaru L, Wolfgang MJ, Baldeviano GC, Wong GW. C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes. J Biol Chem. 2012 Mar 23;287(13):10301-15.
http://www.jbc.org/content/287/13/10301.long
Key words: diabetes, obesity, insulin resistance
PMID: 22275362

1. Biteen JS, Goley ED, Shapiro L, Moerner WE. Three-dimensional super-resolution imaging of the midplane protein FtsZ in live Caulobacter crescentus cells using astigmatism. Chemphyschem. 2012; 13: 1007-12.
Key words: astigmatic lens; live-cell imaging; FtsZ; single-molecule studies; three-dimensional imaging
http://www.ncbi.nlm.nih.gov/pubmed/22262316

2. Blum DJ, Ko YH, Pedersen PL. Mitochondrial ATP synthase catalytic mechanism: a novel visual comparative structural approach emphasizes pivotal roles for mg(2+) and p-loop residues in making ATP. Biochemistry. 2012;51(7):1532-46.
Key words: mitochondria, oxidative phosphorylation, ATP synthase, reaction mechanism
http://www.ncbi.nlm.nih.gov/pubmed/22243519

3. Ko YH, Verhoeven HA, Lee MJ, Corbin DJ, Vogl TJ, Pedersen PL. A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside. J Bioenerg Biomembr. 2012 Feb;44(1):163-70.
Key words: liver cancer, energy metabolism, anti-cancer agent, 3-bromopyruvate
http://www.ncbi.nlm.nih.gov/pubmed/22328020

4. Lis P, Zarzycki M, Ko YH, Casal M, Pedersen PL, Goffeau A, U?aszewski.S. Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae. J Bioenerg Biomembr. 2012 2012 Feb;44(1):155-61.
Key words: Yeast, cancer, energy metabolism, anti-cancer agent, 3-bromopyruvate
http://www.ncbi.nlm.nih.gov/pubmed/22359102

5. Pedersen PL. 3-bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: introduction to a special issue. J Bioenerg Biomembr. 2012 Feb;44(1):155-61.
Key words: anti-cancer agent, 3-bromopyruvate, human cancer
http://www.ncbi.nlm.nih.gov/pubmed/22382780

6. Queirós O, Preto A, Pacheco A, Pinheiro C, Azevedo-Silva J, Moreira R, Pedro M, Ko YH, Pedersen PL, Baltazar F. Casal M. Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate. J Bioenerg Biomembr. 2012 Feb;44(1):141-53.
Key words: breast cancer, energy metabolism, MCT4, 3-bromopyruvate
http://www.ncbi.nlm.nih.gov/pubmed/22350013

1. Lee Y, Kang, MJ, Shim J, Cheong CU, Moon SJ, Montell C. Gustatory receptors required for avoiding the insecticide L-canavanine. J Neurosci. 2012 Jan 25; 32(4):1429-35
Key words: L-Canavanine, gustatory receptor neuron, bitter taste signaling

2. Peng X, Maiers JL, Choudhury D, Craig SW, Demali KA. Alpha catenin uses a novel mechanism to activate vinculin. J Biol Chem. 2012 Jan 10. [Epub ahead of print].
Key words: Vinculin, Cell adhesion, Alpha-catenin
http://www.ncbi.nlm.nih.gov/pubmed/22235119

3. Huang YWA, Ruiz CR, Eyler EC, Lin K, Meffer MK. Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesis. Cell. 2012; 148 (5).
Key words: Neurotrophin; protein synthesis; microRNA
No PMID available

1. Munns CH, Caterina MJ. Tune in to KCNQ. Nat Neurosci. 2011 Dec 23;15(1):8-10.
Key words: channel, mechanoreceptor, vibration, somatosensation
http://www.nature.com/neuro/journal/v15/n1/full/nn.3012.html
PMID: 22193251

1. Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM. Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. J Cell Biol. 2011 Oct 17;195(2):263-76. Epub 2011 Oct 10.
Key words: mitochondria Bcl-xl
http://www.ncbi.nlm.nih.gov/pubmed/21987637

1. He, L, Wang, X, Montell, D.J. Shining light on Drosophila oogenesis: live imaging of egg development. Curr Opin Genet Dev. 2011 Sept 17 [Epub ahead of print].
Key words: cell migration, Drosophila, Genetics, JAK/STAT, morphogen
http://www.ncbi.nlm.nih.gov/pubmed/21930372

2. Prasad, M., Wang, X., He, L., and Montell, D.J. Border cell migration: a model system for live imaging and genetic analysis of collective cell movement. Methods Mol Biol 2011; 769, 277-286.
Key words: Border cell migration, Drosophila stage 9 egg chambers, organ culture, collective cell migration, Time-lapse live imaging
http://www.ncbi.nlm.nih.gov/pubmed/21748683

3. Yoon, W.H., Meinhardt, H., and Montell, D.J.) miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold. Nat Cell Biol; 2011 Aug 21; 13(9); 1062-1069.
Key words: cell migration, Drosophila, genetics
http://www.ncbi.nlm.nih.gov/pubmed/21857668

1. He, L, Wang, X, Montell, D.J. Shining light on Drosophila oogenesis: live imaging of egg development. Curr Opin Genet Dev. 2011 Sept 17 [Epub ahead of print].
Key words: cell migration, Drosophila, Genetics, JAK/STAT, morphogen
http://www.ncbi.nlm.nih.gov/pubmed/21930372

2. Prasad, M., Wang, X., He, L., and Montell, D.J. Border cell migration: a model system for live imaging and genetic analysis of collective cell movement. Methods Mol Biol 2011; 769, 277-286.
Key words: Border cell migration, Drosophila stage 9 egg chambers, organ culture, collective cell migration, Time-lapse live imaging
http://www.ncbi.nlm.nih.gov/pubmed/21748683

3. Yoon, W.H., Meinhardt, H., and Montell, D.J.) miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold. Nat Cell Biol; 2011 Aug 21; 13(9); 1062-1069.
Key words: cell migration, Drosophila, genetics
http://www.ncbi.nlm.nih.gov/pubmed/21857668

1. Park U, Vastani N, Guan Y, Raja SN, Koltzenburg M, Caterina MJ. TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception. J Neurosci. 2011 Aug 10;31(32):11425-36.
Key words: Pain, channel, Neuron, Transient Receptor Potential
http://www.ncbi.nlm.nih.gov/pubmed/21832173

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