Web notes  
September 2013
PUBLICATIONS - Back

Oncology
[Oncology archives]

1. Beaver JA, Gustin JP, Yi KH, Rajpurohit A, Thomas M, Gilbert SF, Rosen DM, Park BH, Lauring J. PIK3CA and AKT1 mutations have distinct effects on sensitivity to targeted pathway inhibitors in an isogenic luminal breast cancer model system. Clin Cancer Res. 2013 Jul 25. [Epub ahead of print]
Key words: isogenic, inhibitors, breast cancer
http://www.ncbi.nlm.nih.gov/pubmed/23888070

2. Fu C, van der Zwan A, Gerber S, Van Den Berg S, No E, Wang W, Sheibani N, Carducci MA, Kachhap S, Hammers HJ. Screening assay for blood vessel maturation inhibitors. Biochem Biophys Res Commun. 2013 Jul 25. doi:pii: S0006-291X(13)01239-4. 10.1016/j.bbrc.2013.07.077. [Epub ahead of print]
Key words: screening, blood vessel, inhibitors
http://www.ncbi.nlm.nih.gov/pubmed/23892038

3. Gantt S, Casper C, Ambinder RF. Insights into the broad cellular effects of nelfinavir and the HIV protease inhibitors supporting their role in cancer treatment and prevention. Curr Opin Oncol. 2013 Jul 18. [Epub ahead of print]
Key words: nelfinavir, HIV, inhibitors
http://www.ncbi.nlm.nih.gov/pubmed/23872785

4. Herman JM, Fan KY, Wild AT, Hacker-Prietz A, Wood LD, Blackford AL, Ellsworth S, Zheng L, Le DT, De Jesus-Acosta A, Hidalgo M, Donehower RC, Schulick RD, Edil BH, Choti MA, Hruban RH, Pawlik TM, Cameron JL, Laheru DA, Wolfgang CL. Phase 2 study of erlotinib combined with adjuvant chemoradiation and chemotherapy in patients with resectable pancreatic cancer. Int J Radiat Oncol Biol Phys. 2013 Jul 15;86(4):678-85. doi: 10.1016/j.ijrobp.2013.03.032.
Key words: erlotinib, pancreatic cancer, chemotherapy
http://www.ncbi.nlm.nih.gov/pubmed/23773391

5. Kortenhorst MS, Wissing MD, Rodríguez R, Kachhap SK, Jans JJ, Van der Groep P, Verheul HM, Gupta A, Aiyetan PO, van der Wall E, Carducci MA, Van Diest PJ, Marchionni L. Analysis of the genomic response of human prostate cancer cells to histone deacetylase inhibitors. Epigenetics. 2013 Jul 19;8(9). [Epub ahead of print]
Key words: deacetylase, prostate cancer, histone
http://www.ncbi.nlm.nih.gov/pubmed/23880963

6. Pelosof L, Yerram SR, Ahuja N, Delmas A, Danilova L, Herman JG, Azad NS. CHFR silencing or microsatellite instability is associated with increased anti-tumor activity of docetaxel or gemcitabine in colorectal cancer. Int J Cancer. 2013 Jul 20. doi: 10.1002/ijc.28390. [Epub ahead of print]
Key words: colorectal cancer, docetaxel, instability
http://www.ncbi.nlm.nih.gov/pubmed/23873170

7. Poirier JT, Dobromilskaya I, Moriarty WF, Peacock CD, Hann CL, Rudin CM. Selective tropism of seneca valley virus for variant subtype small cell lung cancer. J Natl Cancer Inst. 2013 Jul 17;105(14):1059-65. doi: 10.1093/jnci/djt130. Epub 2013 Jun 5.
Key words: tropism, Seneca valley, lung cancer
PubMed PMID: 23739064.
http://www.ncbi.nlm.nih.gov/pubmed/23739064

8. Ray Banerjee S, Pullambhatla M, Foss CA, Falk A, Byun Y, Nimmagadda S, Mease RC, Pomper MG. Effect of Chelators on the Pharmacokinetics of (99m)Tc-Labeled Imaging Agents for the Prostate-Specific Membrane Antigen (PSMA). J Med Chem. 2013 Jul 22. [Epub ahead of print]
Key words: antigen, prostate cancer
http://www.ncbi.nlm.nih.gov/pubmed/23799782

9. Stearns V, Jacobs LK, Fackler M, Tsangaris TN, Rudek MA, Higgins M, Lange J, Cheng Z, Slater SA, Jeter SC, Powers P, Briest S, Chao C, Yoshizawa C, Sugar E, Espinoza-Delgado I, Sukumar S, Gabrielson E, Davidson NE. Biomarker Modulation following Short-Term Vorinostat in Women with Newly Diagnosed Primary Breast Cancer. Clin Cancer Res. 2013 Jul 15;19(14):4008-16. doi: 10.1158/1078-0432.CCR-13-0033. Epub 2013 May 29.
Key words: vorinostat, breast cancer
http://www.ncbi.nlm.nih.gov/pubmed/23719261

10. Vendetti FP, Rudin CM. Epigenetic therapy in non-small-cell lung cancer: targeting DNA methyltransferases and histone deacetylases. Expert Opin Biol Ther. 2013 Jul 17. [Epub ahead of print]
Key words: DNA, epigenetic, lung cancer
http://www.ncbi.nlm.nih.gov/pubmed/23859704


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September 2013 articles:
Revised Investigational Drug Data Sheet
eIRB 2 Launch and Information Sessions
eIRB 101 Enrollment is Now Available Through myLearning
eIRB Non-JHED User Self-Registration
Compliance Monitoring Program Information Session
 
Visit Animal Care and Use Committee Website
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Funding from Foundations/Private Sources
Fondation Leducq Transatlantic Networks of Excellence Program
Microsoft Faculty Research Fellowship for 2014
Burroughs Wellcome Fund - Investigators in the Pathogenesis of Infectious Disease Program
Tang Prize in Biopharmaceutical Science and Tang Prize in Sustainable Development
2014 NIH Director's Early Independence Awards

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