Web notes  
November 2012

[Oncology archives]

1. Armanios M, Blackburn EH. The telomere syndromes. Nat Rev Genet. 2012 Oct;13(10):693-704. doi: 10.1038/nrg3246. Epub 2012 Sep 11.
Key words: telomere, syndromes

2. Boikos SA, Hammers HJ. Denosumab for the treatment of bisphosphonate-refractory hypercalcemia. J Clin Oncol. 2012 Sep 4. [Epub ahead of print]
Key words: denosumab, bisphosphonate, hypercalcemia
PubMed PMID: 22949145.

3. Brennen WN, Rosen DM, Wang H, Isaacs JT, Denmeade SR. Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug. J Natl Cancer Inst. 2012 Sep 5;104(17):1320-34. Epub 2012 Aug 21.
Key words: tumor stroma, fibroblast, prodrug

4. Chen S, Principessa L, Isaacs JT. Human prostate cancer initiating cells isolated directly from localized cancer do not form prostaspheres in primary culture. Prostate. 2012 Sep 15;72(13):1478-89. doi: 10.1002/pros.22503. Epub 2012 Mar 6.
Key words: prostaspheres, prostate cancer

5. Chu SH, Heiser D, Li L, Kaplan I, Collector M, Huso D, Sharkis SJ, Civin C, Small D. FLT3-ITD Knockin Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm. Cell Stem Cell. 2012 Sep 7;11(3):346-58.
Key words: neoplasm, quiescence, homeostasis, myeloproliferative

6. D'Souza G, Burk RD, Zhong Y, Minkoff H, Massad LS, Xue X, Watts DH, Anastos K, Palefsky JM, Levine AM, Colie C, Castle PE, Strickler HD. Cervicovaginal human papillomavirus (HPV)-infection before and after hysterectomy: evidence of different tissue tropism for oncogenic and nononcogenic HPV types in a cohort of HIV-positive and HIV-negative women. Int J Cancer. 2012 Sep 15;131(6):1472-8. doi: 10.1002/ijc.27363. Epub 2012 Jan 3.
Key words: HPV, hysterectomy, tissue tropism

7. Fuchs EJ. Human leukocyte antigen-haploidentical stem cell transplantation using T-cell-replete bone marrow grafts. Curr Opin Hematol. 2012 Sep 5. [Epub ahead of print]
Key words: T cell, bone marrow, leukocyte, grafts

8. Jones RJ. Haploidentical transplantation - repurposing cyclophosphamide. Biol Blood Marrow Transplant. 2012 Sep 27. pii: S1083-8791(12)00370-9. doi: 10.1016/j.bbmt.2012.09.005. [Epub ahead of print]
Key words: cyclophosphamide, haploidentical, transplantation
PubMed PMID: 23022466.

9. McMillan R, Matsui W. Molecular pathways: the hedgehog signaling pathway in cancer. Clin Cancer Res. 2012 Sep 15;18(18):4883-8. Epub 2012 Jun 19.
Key words: hedgehog, signaling , pathway

10. Poirier JT, Reddy PS, Idamakanti N, Li SS, Stump KL, Burroughs KD, Hallenbeck PL, Rudin CM. Characterization of a full-length infectious cDNA clone and a green fluorescent protein reporter derivative of the oncolytic picornavirus SVV-001. J Gen Virol. 2012 Sep 12. [Epub ahead of print]
Key words: cDNA, picornavirus, green

11. Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, Haverty PM, Gentleman R, Chaudhuri S, Janakiraman V, Jaiswal BS, Parikh C, Yuan W, Zhang Z, Koeppen H, Wu TD, Stern HM, Yauch RL, Huffman KE, Paskulin DD, Illei PB, Varella-Garcia M, Gazdar AF, de Sauvage FJ, Bourgon R, Minna JD, Brock MV, Seshagiri S. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet. 2012 Oct;44(10):1111-6. doi: 10.1038/ng.2405. Epub 2012 Sep 2.
Key words: lung cancer, genomic analysis, SOX2

12. Santa-Maria CA, Cimino-Mathews A, Moseley KF, Wolff AC, Blakeley JO, Connolly RM. Complete Radiologic Response and Long-Term Survival With Use of Systemic High-Dose Methotrexate for Breast Cancer-Associated Leptomeningeal Disease. Clin Breast Cancer. 2012 Sep 22. pii: S1526-8209(12)00174-7. doi: 10.1016/j.clbc.2012.07.010. [Epub ahead of print]
Key words: breast cancer, methotrexate, leptomeningeal

13. Sexauer A, Perl A, Yang X, Borowitz M, Gocke C, Rajkhowa T, Thiede C, Frattini M, Nybakken GE, Pratz K, Karp J, Smith BD, Levis M. Terminal myeloid differentiation in vivo is induced by FLT3 inhibition in FLT3/ITD AML. Blood. 2012 Sep 25. [Epub ahead of print]
Key words: terminal, FLT3, differentiation

14. Suarez L, Gore SD. Cp-jeez! Aza-natomy! Blood. 2012 Sep 20;120(12):2354-5.
Key words: cp-jeez, aza-natomy

15. Waickman AT, Powell JD. mTOR, metabolism, and the regulation of T-cell differentiation and function. Immunol Rev. 2012 Sep;249(1):43-58. doi: 10.1111/j.1600-065X.2012.01152.x.
Key words: mTOR, metabolism, T-cell
PubMed PMID: 22889214; PubMed Central PMCID: PMC3419491.


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