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November 2008
PUBLICATIONS - Back

Cell Biology Archives

1. Dikeman DA, Rivera Rosado LA, Horn TA, Alves CS, Konstantopoulos K, Yang JT. alpha4beta1 integrin regulates directionally persistent cell migration in response to shear flow stimulation. Am J Physiol Cell Physiol 2008 Jul;296:151-159.
Key words: integrin; cell migration; shear flow; lamellipodia
http://www.ncbi.nlm.nih.gov/pubmed/18495811?ordinalpos=4&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

2. Hughes AL, Stewart EV and Espenshade PJ. Identification of 23 mutations in fission yeast Scap that constitutively activate SREBP. J. Lipid Research. 2008 Sep;49(9):2001-12.
Key words: SREBP, cholesterol, fission yeast, Scap, sterol sensing domain, pombe
http://www.ncbi.nlm.nih.gov/pubmed/18503029?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

3. Kerman BE, Cheshire AM, Myat MM, Andrew DJ. Ribbon modulates apical membrane during tube elongation through Crumbs and Moesin. Dev Biol 2008 Aug 1;320(1):278-88.
Key words: apical membrane; crumbs; lola like; moesin; Rab11; ribbon; tube morphogenesis
http://www.ncbi.nlm.nih.gov/pubmed/18585700?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

4. Tang L, Franca-Koh J, Xiong Y, Chen M-Y, Long Y, Bickford, RM, Knecht DA, Iglesias PA, Devreotes, PN. Tsunami, the Dictyostelium homolog of the Fused kinase is required for polarization and chemotaxis. Genes Dev 2008 Aug 15;22(16):2278-90.
Key words: chemotaxis; Dictyostelium; Fused; polarization
http://www.ncbi.nlm.nih.gov/pubmed/18708585?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

5. Yang L, Effler JC, Kutscher BL, Sullivan SE, Robinson DN, Iglesias PA. Modeling cellular deformations using the level set formalism. BMC Systems Bio 2008 Jul 24;2(1):68.
Key words: cell shape; level set formalism; cytokinesis; chemotaxis
http://www.ncbi.nlm.nih.gov/pubmed/18652669?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Iglesias PA, Devreotes PN. Navigating through models of chemotaxis. Curr Opin Cell Bio 2008 Feb;20(1):35-40.
Key words: chemotaxis; mathematical models; polarization
http://www.ncbi.nlm.nih.gov/pubmed/18207721?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

2. Reichl EM, Ren Y, Morphew MK, Delannoy M, Effler JC, Girard KD, Divi S, Iglesias PA, Kuo SC, Robinson DN. Interactions between myosin and actin crosslinkers control cytokinesis contractility dynamics and mechanics. Curr Biol 2008 Apr 8;18(7):471-80. (Cover article)
Key words: Cytokinesis; myosin; actin; actin crosslinkers; cell shape, cell mechanics
http://www.ncbi.nlm.nih.gov/pubmed/18372178?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Braiterman LT, Heffernan S, Nyasae L, Johns D, See AP, Yutzy R, McNickle A, Herman M, Sharma A, Naik UP, and Hubbard AL. JAM-A is both essential and inhibitory to the development of hepatic polarity in WIF-B cells. AJP-Gastro Liver Phys 2008 Feb;294(2):G576-88.
Key words: Hepatic polarity, JAM-A, Knock down
http://www.ncbi.nlm.nih.gov/pubmed/18096610?ordinalpos=1&itool=EntrezSystem2.
PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum

1. Goldberg HR, Dintzis R. The positive impact of team-based virtual microscopy on student learning in physiology and histology. Advances in Physiology Education 2007 Sept;31(3):261-265.
Key words: educational technology; active learning; virtual microscopy
http://advan.physiology.org/cgi/content/full/31/3/261
PMID: 17848592

2. Kabacoff C, Xiong Y, Musib R, Reichl EM, Kim J, Iglesias PA, Robinson DN. Dynacortin facilitates polarization of chemotaxing cells. BMC Biol. 2007 Nov 26;5(1):53.
Key words: Chemotaxis, Dictyostelium, dynacortin, polarization, skeletons
http://www.biomedcentral.com/1741-7007/5/53
PMID: 18039371

3. LeDuc PR, Robinson DN. Using lessons from cellular and molecular structures for future materials. Adv. Mat. 2007;19(22): 3761-3770.
Key words: composite materials, cytoskeleton, cell shape, cell dynamics, mechanics
http://www3.interscience.wiley.com/cgi-bin/fulltext/116835608/PDFSTART?
CRETRY=1&SRETRY=

1. Alder NN, Sutherland J, Buhring AI, Jensen RE, Johnson AE. Quaternary structure of the mitochondrial TIM23 complex reveals dynamic association between Tim23p and other subunits.Mol Biol Cell. 2007 Oct 24; [Epub ahead of print]
PMID: 17959826

2. Reichl EM, Robinson DN. Putting the brakes on cytokinesis with alpha-actinin. Dev. Cell 2007 Oct;13(4):460-462.
Key words: alpha-actinin, actin, myosin-II, cytokinesis
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&
TermToSearch=17925221

3. Sbodio JI, Machamer CE. Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with golgin-160. J Bio Chem 2007 Oct 12;282 (41):29874-29881.
Keywords: GCP60; golgin-160; redox-sensitive; PAP7; ACBD3
http://www.jbc.org/cgi/reprint/282/41/29874
PMID: 17711851

1. Espenshade PJ. Sterols regulate ER-to-Golgi transport of SREBP cleavage activating protein (SCAP). ASCB Image & Video Library. June 2007:VID-32.
http://cellimages.ascb.org/cdm4/item_viewer.php?CISOROOT=/p4041coll7&
CISOPTR=164&CISOBOX=1&REC=1

2. Hughes AL, Lee CY, Bien CM, Espenshade PJ. 4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress. J. Biol. Chem. 2007 Aug 17;282 (33):24388-96.
Key words: lanosterol; SREBP; oxygen; yeast; hypoxia
http://www.jbc.org/cgi/content/full/282/33/24388
PMID: 17595166

3. Lee H, Bien CM, Hughes AL, Espenshade PJ, Kwon-Chung KJ. Cobalt chloride, a hypoxia-mimicking agent, targets sterol synthesis in the pathogenic fungus Cryptococcus neoformans. Mol. Microbiol. 2007 Aug;65:1018-1033.
Key words: Cryptococcus neoformans; SREBP; oxygen; yeast; hypoxia
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2007.05844.x
PMID: 17645443

4. Sasaki AT, Janetopoulos C, Lee S, Charest PG, Takeda K, Sundheimer LW, Meili R, Devreotes PN, Firtel RA. G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility. J Cell Bio 2007 Jul 16;178(2):185-191.
Key words: G protein; cell motility; PI3K; Dictyostelium; Ras
http://www.jcb.org/cgi/content/full/178/2/185
PMID: 17635933

5. Sehgal A, Lee CY, Espenshade PJ. SREBP controls oxygen-dependent mobilization of retrotransposons in fission yeast. PLoS Genet 2007 Aug 10;3(8):e131.
Key words: SREBP; cholesterol; yeast; transposons; oxygen
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&
TermToSearch=17696611

1. Chang YC, Bien CM, Lee H, Espenshade PJ, and Kwon-Chung KJ. Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans. Molecular Microbiology 2007 May;64(3):614-629.
Key words: cryptococcus neoformans; SREBP; oxygen; hypoxia
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2007.05676.x
PMID: 17462012

2. Chen L, Iijima M, Tang M, Landree MA, Huang YE, Xiong Y, Iglesias PA, Devreotes PN PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis. Dev. Cell 2007 Apr;12(4):603-614.
Key words: chemotaxis; PLA2; PI(3,4,5)P3; arachidonic acid; D. discoideum
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WW3-4NFR3K5-
F&_user=75682&_coverDate=04%2F30%2F2007&_rdoc=1&_fmt=&_orig=search
&_sort=d&view=c&_acct=C000006078&_version=1&_urlVersion=0&_userid=
75682&md5=f4c7260a1405f651e608ad3fdfa99589
PMID: 17419997

3. Paumi CM, Menendez J, Arnoldo A, Engels K, Iyer KR, Thaminy S, Georgiev O, Barral Y, Michaelis S, Stagljar I. Mapping protein-protein interactions for the yeast ABC transporter Ycflp by integrated split-ubiquitin membrane yeast two-hybrid analysis. Mol Cell 2007 Apr;26 (1):15-25.
Key words: iMYTH; "split-ubiquitin"; Ycflp; ABC transporter; Tuslp
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSR-4NGCY1R-
2&_user=75682&_coverDate=04%2F13%2F2007&_rdoc=1&_fmt=&_orig=search&
_sort=d&view=c&_acct=C000006078&_version=1&_urlVersion=0&_userid=
75682&md5=9239393c09ec80bc42df013fdabab26e
PMID: 17434123

1. Abrams E, Mihoulides WK, Andrew DJ. Fork head and Sage maintain a uniform and patent salivary gland lumen through regulation of two downstream target genes, PH4ÿSG1 and PH4ÿSG2. Development 2006;133:3517-3527.
Key words: Drosophila; Fork head (Fkh); Prolyl-4-hydroxylase; Sage; salivary gland; tube morphogenesis
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
AbstractPlus&list_uids=16914497

2. Huyer G, Kistler A, Nouvet FJ, George C, Boyle ML, Michaelis S. Saccharomyces cerevisiae a-factor mutants reveal residues critical for processing, activity, and export. Eukaryotic Cell 2006;5:1560-1570.
Key words: prenylation; mating; pheromones; lamin A
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
AbstractPlus&list_uids=16963638

3. Sbodio JI, Hicks SW, Simon D, Machamer CE. GCP60 preferentially interats with a caspase-generated golgin-160 fragment. J Bio Chem 2006;281:27924-27931.
Key words: Golgi, golgin, caspase cleavage, nuclear translocation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
AbstractPlus&list_uids=16870622

4. Willard S, Devreotes PN. Signaling pathways mediating chemotaxis in the social amoebae, Dictyostelium discoideum. Eur J Cell Biol 2006;85:897-904.
Key words: chemotaxis, Dictyostelium discoideum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
AbstractPlus&list_uids=16962888

1. Dahl KN, Scaffidi P, Islam MF, Yodh AG, Wilson KL, Misteli T. Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci USA 2006;103:10271-10276.
Key words: laminopathy, mechanics, nucleus, Hutchinson-Gilford progeria
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
AbstractPlus&list_uids=16801550

1. Franca-Koh J, Kamimura Y, Devreotes PN. Navigating signaling networks: chemotaxis in Dictyostelium discoideum. Curr Opin in Gen & Dev. 2006;16:333-338.
Key words: chemotaxis; signal transduction; Dictyostelium discoideum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
Abstract&list_uids=16782326

2. Sesaki H, Dunn CD, Iijima M, Shepard KA, Yaffe MP, Machamer CE, Jensen RE. Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p. J Cell Biol 2006;173:651-658.
Key words: mitochondria; protein sorting; organelle morphology
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=
Abstract&list_uids=1675495

1. Lerin C, Rodgers JT, Kalume DE, Kim S-H, Pandey A, Puigserver P. GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab 2006;3:429-438.
Key words: diabetes; gluconeogenesis; transcriptional regulation; PGC-1alpha
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16753578

1. Grazioli A, Alves CS, Konstantopoulos K, Yang JT. Defective blood vessel development and pericyte/pvSMC distribution in a4 integrin-deficient mouse embryos. Dev Bio 2006;293:164-177.
Key words: blood vessel development; cell motility; a4b1 integrin; fibronectin; pericyte; presumptive vascular smooth muscle cell
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16529735

2. Loovers HM, Postma M, Keizer-Gunnink I, Huang YE, Devreotes PN, van Haastert PJ. Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in dictyostelium: A quantitative in vivo analysis by inhibition of PI3-kinase. Mol Biol Cell 2006;17:1503-1513.
Key words: PI3-kinase, chemoattractant signaling, dictyostelium
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=1642125

1. Effler JC, Iglesias P, Robinson DN. Regulating cell shape during cytokinesis. In B.A.Francis and J.C.Willems, eds, Control of Uncertain Systems: Modelling, Approximation and Design, 2006; pp. 203-224. Springer-Verlag, New York.
Key words: cytokinesis; mechanical feedback; cell shape; viscoelasticity

2. Espenshade P. SREBPs: sterol-regulated transcription factors (Review). J Cell Sci. 2006;119:973-976.
Key words: SREBP; yeast; transcription factor; sterol
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16525117

3. Girard KD, Kuo SC, Robinson DN. Dictyostelium myosin-II mechanochemistry promotes active behavior of the cortex on long time-scales. PNAS 2006;103:2103-2108.
Key words: cell mechanics; dynacortin; laser-based particle tracking; nanoscale
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16461463

4. Ibarra N, Blagg SL, Vazquez F, Insall RH. Nap1 regulates dictyostelium cell motility and adhesion through SCAR-dependent and -independent pathways. Curr. Biol. 2006;16:717-722.
Key words: signaling; SCAR-dependent; dictyostelium; Nap1
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16581519

5. Matsuoka S, Ueda M, Watanabe T, Kuwayama H, Devreotes PN, Yanagida T. Single-molecule analysis of chemoattractant-stimulated membrane recruitment of a PH-domain-containing protein. J Cell Sci 2006;119:1071-1079.
Key words: single molecule; PH-domain; PIP3; plasma membrane
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16507590

6. Todd BL, Stewart EV, Burg JS, Hughes AL, Espenshade PJ. Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast. Mol Cell Biol 2006;26:2817-2831.
Key words: SREBP; yeast; hypoxia; sterol
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16537923

7. Vazquez F, Matsuoka S, Sellers WR, Yanagida T, Ueda M, Devreotes PN. Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane. PNAS 2006;103:3633-3638.
Key words: PTEN; plasma membrane; tumor suppressor; lipid phosphatase
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16537447

1. de Oca RM, Lee KK, Wilson KL. Binding of barrier to autointegration factor (BAF) to histrone H3 and selected linker histones including H1.1. J Biol Chem 2005;280:42252-62.
Key words: barrier to autointegration factor; histones; chromatin
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16203725

2. Pendleton AR, Machamer CE. Differential localization and turnover of infectious bronchitis virus 3b protein in mammalian versus avian cells. Virology 2006;345:337-345.
Key words: infectious bronchitis virus; accessory protein; IBV 3b; protein degradation; ubiquitin; proteasome
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16298409

1. Mallampalli MP, Huyer G, Bendale P, Gelb MH, Michaelis S. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome. PNAS 2005;102:14416-14421.
Key words: Aging, lamin A, posttranslational processing, Zarnestra, Ste24
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16186497

2. Youn S, Collisson EW, Machamer CE. Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection. J Viol 2005;79:13209-13217.
Key words: coronoavirus, spike protein, endocytosis
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=16227244

1. Hicks S, Machamer C. Golgi structure in stress sensing and apoptosis. Biochim Biophys Acta. 2005 Jul 10; 1744(3):406-14.
Key words: Golgi, apoptosis, stress, signaling
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15979510

1. Abrams EW, Andrew DJ. CrebA regulates secretory activity in the Srosophila salivary gland and epidermis. Development 2005 132:2743-2758.
Key words: CrebA, Drosophila, epidermis, salivary gland, secretion
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15901661

2. Maag RS, Mancini M, Rosen A, Machamer CE. Caspase-resistant golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. Mol Biol Cell 2005 16:3019-3027.
Key words: Golgi complex, apoptosis, golgin-160, TNFR-1, ER stress
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15829563

1. Myat MM, Lightfoot H, Wang P, Andrew DJ. A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea. Dev Biol 2005;281:38-52.
Key words: cell migration, Drosophila, Dpp-signaling, FGF-signaling, trachea
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15848387

2. Pendleton AR, Machamer CE. Infectious bronchitis virus 3a protein localizes to a novel domain of the smooth endoplasmic reticulum. J Virol 2005;79:6142-6151.
Key words: infectious bronchitis virus, smooth endoplasmic reticulum, small non-structural proteins, 3a protein http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15857999

3. Puigserver P. Tissue-specific regulation of metabolic pathways through the transcriptional coactivator PGC1-alpha. Int J Obes Relat Metab Disord. 2005 Mar;29 Suppl 1:S5-9.
Key words: energy metabolism, transcriptional regulation, fat cell differentiation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15711583

4. Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 2005;434:113-8.
Key words: calorie restriction, diabetes, life span, transcriptional nutrient sensor
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15744310

5. Zhang W, Robinson DN. Balance of actively generated contractile and resistive forces controls cytokinesis dynamics. Proc Nat Acad Sc. USA 2005;102:7186-7191.
Key words: cell dynamics, myosin II, dynacortin, RacE, cell mechanics
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15870188

1. Hughes A, Todd B, Espenshade P. SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell 2005;120:831-842.
Key words: cholesterol, sterol, fission yeast, SREBP, SCAP
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15797383

2. Janetopoulos C, Borleis J, Vazquez F, Iijima M, Devreotes PN Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis. Dev. Cell 2005;8:467-477.
Key words: polarity, phosphoinositides, chemotaxis
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15809030

3. Mansharamani M, Wilson KL. Direct binding of nuclear membrane protein MAN1 to emerin in vitro and two modes of binding to barrier-to-autointegration factor. J Biol Chem 2005;280:13863-13870.
Key words: Emery-Dreifuss muscular dystrophy, laminopathy, emerin, MAN1, nuclear envelope
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15681850

4. Reichl EM, Effler J, Robinson DN. Stress and strain of cytokinesis. Trends Cell Biol 2005;15:200-206.
Key words: actin, cell division, cell mechanics, cytoskeleton, myosin II, Rac, viscoelasticity
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15817376

5. van Amerongen R, Nawijn M, Franca-Koh J, Zevenhoven J, van der Gulden H, Jonkers J, Berns A. Frat is dispensable for canonical Wnt signaling in mammals. Genes Dev. 2005;19:425-430.
Key words: Wnt signalling, GSK-3, Frat, GBP
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15681612


1. Ma L, Janetopoulos C, Yang L, Devreotes PN, Iglesias PA. Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in Dictyostelium cells. Biophys J. 2004;87:3764-74.
Key words: model, virtual cell, migration
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15465874

1. Janetopoulos C, Ma L, Iglesias PA, Devreotes PN Chemoattractant-induced temporal and spatial PI(3,4,5)P3 accumulation is controlled by a local excitation, global inhibition mechanism. PNAS 2004;101(24):8951-8956.
Key words: chemoattractant; excitation, inhibition mechanism
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list-uids=15184679

1. Chen C, Ko Y, Delannoy M, Ludke SJ, Chiu W, Pedersen PL. Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. J Biol Chem 2004;279(30):31761-8.
Key words: ATP synthase, phosphate ADP and ATP carriers, three dimensional structure
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15166242

2. Chen JO, Delannoy M, Cooke C, Yager JD. Mitochondrial localization of ERalpha and ERbeta in human MCF7 cells. Am J Physiol Endocrinol Metab. 2004;86(6):E1011-22.
Key words: Alpha and Beta estrogen receptors, estradiol effects, mitochondrial matrix, confocal and immunoelectron microscopy
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=14736707

3. Chen J, Delannoy M, Odwin S, He P, Trush MA, Yager JD. Enhanced mitochondrial gene transcript, ATP, bcl-2 protein levels, and altered glutathione distribution in ethinyl estradiol-treated cultured female rat hepatocytes. Toxicol Sci. 2003;75(2):271-8.
Key words: mitochondrial gene transcription, ATP, bcl-2 protein, glutathione, estradiol and confocal microscopy
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=12857939

4. Franca-Koh J, Devreotes PN. Moving forward: mechanisms of chemoattractant gradient sensing. Physiology 2004;19:300-308.
Key words: chemotaxis, gradient sensing, actin regulation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15381759

5. Huyer G, Piluek WF, Fansler Z, Kreft SG, Hochstrasser M, Brodsky JL, Michaelis S. Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein. J Biol Chem 2004;279(37):38369-78.
Key words: ER quality control, ubiquitination, proteasome, molecular chaperones
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15252059

6. Manahan C, Iglesias P, Devreotes PN. Annual Review - Chemoattractant signaling in Dictyosteium discoideum. Cell Dev Biol 2004;20:223-53.
Key words: chemotaxis, G-protein signaling, directional sensing
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15473840

7. Van Haastert PJ, Devreotes PN. Chemotaxis: signaling the way forward. Nat Mol Cell Biol 2004;5(8):626-634.
Key words: chemotaxis, polarity, Dictyostelium
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=
Abstract&list_uids=15366706

1. Brawley C, Matunis E. Regeneration of male germline stem cells by spermatogonial dedifferentiation in vivo. Sci Express 2004;304(5675):1331-1334.
Key words: dedifferentiation; germline stem cells; Jak-STAT signaling
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=15143218

2. Hynes TR, Tang L, Mervine SM, Sabo JL, Yost EA, Devreotes PN, Berlot CH. Visualization of G-protein ÿÿ dimers using bimolecular fluorescence complementation demonstrates roles for both ÿ and ÿ in subcellular targeting. J. Biol. Chem. 2004;279(29):30279-30286.
Key words: G-protein signaling; ÿÿ-complex heterogeneity; GFP complementation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=15136579

3. Janetopoulos C, Ma L, Iglesias PA, Devreotes PN Chemoattractant-induced temporal and spatial PI(3,4,5)P 3 accumulation is controlled by a local excitation, global inhibition mechanism. PNAS 2004;101(24):8951-8956.
Key words: G-protein coupled receptors; chemotaxis; gradient sensing; adaptation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=15184679

4. Montell C, Devreotes PN. Annual Review on Cell Regulation - From protein dynamics to animal behavior: new insights into complex cell regulatory mechanisms. Curr. Opin. Cell Biol. 2004;16:115-118.
Key words: cell biology; cell regulation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=15196552

5. Sesaki H, Jensen RE. Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion. J Biol Chem 2004; 279(27):28298-28303.
Key words: mitochondria, organelle dynamics, membrane fusion, yeast
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=15087460

1. Lontok E, Corse E, Machamer CE. Intracellular targeting signals contribute to localization of coronavirus spike proteins near the virus assembly site. J. Virology 2004;78(11)5913-5922.
Key words: coronavirus; spike protein; intracellular targeting
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=15140989

2. Youngman MJ, Aiken-Hobbs AE, Burgess SM, Srinivasan M, Jensen RE. Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 2004;164(5):677-688.
Key words: mitochondria, yeast, mtDNA, outer membrane
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=
pubmed&dopt=Abstract&list_uids=14981098

1. Girard KD, Chaney C, Delannoy M, Kuo SC, Robinson DN. Dynacortin contributes to cortical viscoelasticity and helps define the shape changes of cytokinesis. EMBO J. 2004;23:1536-1546.
Key words: cell morphology, cortical mechanics, cytokinesis, Dictyostelium, rheology
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=pubmed&dopt=Abstract&list_uids=15014435

2. Iijima M, Huang YE, Luo HR, Vazquez F, Devreotes PN Novel mechanism of PTEN regulation by its Phospatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis. J Biol Chem 2004;279(16):16606-16613.
Key words: chemotaxis, PTEN, Dictyostelium discoideum, PI(3,4,5)P3, PI3-Kinase
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=pubmed&dopt=Abstract&list_uids=14764604

3. Kelm KB, Huyer G, Huang JC, Michaelis S. The internalization of yeast Ste6p follows an ordered series of events involving phosphorylation, ubiquitination, recognition and endocytosis. Traffic 2004 Mar;5(3):165-80.
Key words: ABC transporter; endosome localization; protein trafficking; post-translational modification; Saccharomyces cerevisiae
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=pubmed&dopt=Abstract&list_uids=15086792

4. Robinson DN, Spudich JA. Mechanics and regulation of cytokinesis. Curr Opin Cell Biol 2004;16:182-188.
Key words: cytokinesis, cell mechanics, MKLP, myosin, mototic spindle

5. Youngman MJ, Aiken-Hobbs AE, Srinivasan M, McCaffery JM, Jensen RE. Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids. J Cell Biol 2004;164(5):677-688.
Key words: mitochondria, yeast, mtDNA, outer membrane
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=pubmed&dopt=Abstract&list_uids=14981098

1. Cha H, Smith BL, Gallo K, Machamer CE, Shapiro P. Phosphorylation of golgin-160 by Mixed Lineage Kinase-3 (MLK-3). J Cell Science 2004 Feb;15;117(5):751-760.
Key words: golgin-160; phosphorylation; MLK-3; MAP kinase
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db
=pubmed&dopt=Abstract&list_uids=14734651

2. Chen L, Janetopoulos C, Huang YE, Iijima M, Borleis J, and Devreotes PN Two phases of actin polymerization display different dependences on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis. Mol. Biol. Cell 2003 14(12):5028-5037.
Key words: Chemotaxis; Actin polymerization; PI(3,4,5)P3, D. discoideum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db
=pubmed&dopt=Abstract&list_uids=14595116

3. Fan M, Rhee J, St-Pierre J, Handshin C, Puigserver P, Lin J, Jaeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM Suppression of mitochondrial respiration via p160 Myb binding protein docking on PGC-1a: Modulation by p38 MAPK. Genes Dev. 2004 Feb 1;18(3):278-289.
Key words: Mitochondrial respiration; p38 MAP kinase; transcriptional regulation; diabetes; obesity
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db
=pubmed&dopt=Abstract&list_uids=14744933

4. Huyer G, Longsworth GL, Mason DL, Mallampalli MP, McCaffery JM, Wright RL, Michaelis S. A striking quality control subcompartment in Saccharomyces cerevisiae: The endoplasmic reticulum-associated compartment (ERAC). Mol Biol Cell 2004 Feb;15(2):908-921.
Key words: ER quality control, yeast, ER subcompartment, Ste6p, ER-associated degradation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db
=pubmed&dopt=Abstract&list_uids=14668485

5. Kelm KB, Huyer G, Huang JC, Michaelis S. The internalization of yeast Ste6p follows an ordered series of events involving phosphorylation, ubiquitination, recognition and endocytosis. Traffic 2004;5:165-180.
Key words: ABC transporter; endosome localization; protein trafficking; post-translational modification; Saccharomyces cerevisiae

6. Kutscher B, Devreotes PN, Iglesias PA Local excitation, global inhibition mechanism for gradient sensing: An interactive applet. Sci STKE 2004;219:13.
Key words: chemoattractant; local excitation; global inhibition
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db
=pubmed&dopt=Abstract&list_uids=14872096

1. Chen J, Delannoy M, Odwin S, He P, Thrush MA, Yager JD. 2003 Enhanced mitochondrial gene transcript, ATP, bcl-2 protein levels, and altered glutathione distribution in ethinyl estradiol-treated cultured female rat hepatocytes. Toxicol. Sci. 75(2):271-278.
Key words: ethinyl estradiol, rat hepatocytes, glutathione, mitochondria, apoptosis
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve
&db=PubMed&list_uids=12857939&dopt=Abstract

2. Espenshade PJ, Goldstein JL, Brown, MS. SREBPs: Gene regulation through controlled protein trafficking. In: Handbook of Cellular Signaling (R. Bradwhaw and E. Dennis, eds.). Academic Press, San Diego.
Key words: cholesterol, SREBP, SCAP, ER-Golgi transport

3. Mansharamani M, Graham DR, Monie D, Lee KK, Hildreth JE, Siliciano RF, Wilson KL. Barrier-to-autointegration factor (BAF) binds p55 Gag and Matrix and is a host component of HIV-1 virions. J Virol 2003 Dec 77(24):13084-13092.
Key words: Barrier-to-autointegration factor, HIV-1, nuclear envelope, LEM-domain, nuclear lamina
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve
&db=PubMed&list_uids=14645565&dopt=Abstract

 

1. Cerveny KL, Jensen RE. The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria. Mol. Biol. Cell 2003 Oct;14(10):4126-2139.
Key words: Dynamin-related protein, Mitochondria, GTPase, WD-40 repeats
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=14517324&dopt=Abstract

2. Cohen M, Feinstein N, Wilson KL, and Gruenbaum Y. Nuclear pore protein gp210 is essential for viability in HeLa cells and Caenorhabditis elegans. Mol. Biol. Cell 2003 Oct;14(10):4230-4207.
Key words: membrane fusion, nuclear envelope, nuclear pore complex, nuclear lamina, nuclear organization
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=14517331&dopt=Abstract

3. Dunn CD, Jensen RE. Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA. Genetics 2003 Sep;165(1):35-45.
Key words: translation, cycloheximide, chaperone, potential, ATPase
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=14504216&dopt=Abstract

4. Luo HR, Huang YE, Chen JC, Saiardi A, Iijima M, Huang Y, Nagata E, Devreotes PN, Snyder SH. Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions. Cell 2003;114(5):559-572.
Key words: Inositol pyrophosphates, chemotaxis, PtdIns(3,4,5)P3, PH domain
http://www.cell.com/content/article/fulltext?uid=
PIIS0092867403006408

1. Landree MA, Devreotes PN. Analyzing chemotaxis using Dictyostelium discoideum as a model system. In: Cell Migration in Inflammation and Immunity (D.D'Ambrosio and F.Sinigaglia, eds.). Humana Press, Totowa, NJ. Methods in Molecular Biology 2003;239:91-104.
Key words: dictyostelium discoideum, chemotaxis, review, methods

2. Maag RS, Hicks SW, Machamer CE. Death from within: apoptosis and the secretory pathway. Curr. Opin. in Cell Bio. 2003;Aug;15(4):456-61.
Key words: apoptosis, secretory pathway, ER, Golgi, stress
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12892786&dopt=Abstract

1. Corse E and Machamer C. The cytoplasmic tails of infectious bronchitis virus E and M proteins mediate their interaction. Virology 2003 Jul 20;312(1):25-34.
Key words: coronavirus, virus assembly, envelope protein interactions
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12890618&dopt=Abstract

1. Machamer CE. Golgi disassembly in apoptosis: cause or effect? Trends in Cell Biol. 2003 Jun; 13(6):279-81.
Key words: Golgi complex disassembly, apoptosis
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12791290&dopt=Abstract

2. Mason D, Mallampalli M, Huyer G, Michaelis S. A region within a lumenal loop of Saccharomyces cerevisiae Ycf1p directs proteolytic processing and substrate specificity. Eukaryotic Cell 2003 Jun; 2(3):588-98.
Key words: yeast, MRP, Ycf1p, substrate specificity, proteolytic processing
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12796304&dopt=Abstract

3. Nyasae LK, Hubbard AL, Tuma PL. Transcytotic efflux from early endosomes is dependent on cholesterol and glycosphingolipids in polarized hepatic cells. Mol. Biol. Cell 2003 Jul;14(7):2689-705.
Key words: hepatocytes, protein sorting, lipid rafts, apical proteins
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12857857&dopt=Abstrac
t

4. Sesaki H, Southard SM, Yaffe MP, Jensen RE. Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane. Mol Bio Cell 2003 Jun; 14(6):2342-56.
Key words: mitochondria, membrane fusion, outer membrane, dynamin-related GTPase, yeast
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12808034&dopt=Abstract

5. Tuma, PL, Hubbard, AL Transcytosis: Crossing cellular barriers. Physiological Reviews 2003 Jul; 83(3):871-932.
Key words: polarity, in vivo and in vitro models
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&
db=PubMed&list_uids=12843411&dopt=Abstract

1. Haberman AS, Isaac DD, Andrew DJ. Specification of cell fates within the salivary gland primordium. Dev Bio 2003;258:443-453.
Key words: fork head, imaginal ring, salivary dudct, salivary gland, Serrate

2. Huang YE, Iijima M, Parent CA, Funamoto S, Firtel RA, Devreotes PN. Receptor mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells. Mol Bio Cell 2003;14:1913-1922.
Key words: chemotaxis, D. discoideum, D3 phosphoinositide, PI3K, PTEN

3. Janetopoulos C, Devreotes PN. Eukaryotic chemotaxis: Distinctions between directional sensing and polarization. J. Biol. Chem. 2003;278:20445-20448.
Key words: chemotaxis, polarization, directional sensing

1. Abrams EW, Vining MS, and Andrew DJ. Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends in Cell Bio 2003; May;13(5):247-54.
Key words: apical, cell shape, morphogenesis, salivary glands, tubulogenesis

2. Bradley PL, Myat MM, Comeaux CA, and Andrew DJ. Posterior migration of the salivary gland requires an intact visceral mesoderm and integrin function. Dev Bio 2003; May 15;257(2):249-62.
Key words: cell migration, heartless, integrins, salivary gland, visceral mesoderm

1. Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL. Mitochondrial ATP synthasome: Cristae enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP)/ATP1. J Biol Chem 2003; 278:12305-12309.
Key words: mitochondrial ATP synthasome, ADP/ATP carriers, FESEM, TEM and detergents

2. Liu J, Lee KK, Segura-Totten M, Neufeld E, Wilson KL and Gruenbaum Y. MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in C. elegans. Proc Natl Acad Sci USA 2003; 100:4598-4603.
Key words: laminopathy, nuclear envelope, lamin, barrier to autointegration factor, cell untimely torn

1. Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL. Mitochondrial ATP synthyasome: Cristae enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP)/ATP1. J Biol Chem. 2003 Jan 30; in press [epub ahead of print] (Cover)
Key words: ATP synthase, Pi, ADP/ATP1, mitochondrial ATP synthyasome

2. Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha): Transcriptional coactivator and metabolic regulator. Endocr. Rev. 2003; 24(1):78-90
Key words: PGC-1 proliferator-activated receptor-gamma coactivator 1alpha

3. Tritos NA, Mastaitis JW, Kokkotou EG, Puigserver P, Spiegelman BM, Maratos-Flier E. Characterization of the peroxisome proliferator activated receptor coactivator 1 alpha (PGC 1alpha) expression in the murine brain. Brain Res. 2003; 961(2):255-60
Key words: proliferator-activated receptor-gamma coactivator 1alpha, murine brain

 

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November 2008 articles:
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Online Laboratory Survey
NIH Seeks Proposals for 2009 Director's Pioneer and New Innovator Awards
New! Transformative R01 Program
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