Johns Hopkins scientists have created a free, Web-based tool to help patients decide whether it's best to accept an immediately available, but less-than-ideal deceased donor kidney for transplant, or wait for a healthier one in the future.
An additional 1,000 patients could undergo kidney transplants in the United States annually if hospitals performed more transplants using paired kidney exchanges, new Johns Hopkins research suggests.
Last month, a surgical team led by Johns Hopkins physicians performed The Johns Hopkins Hospital’s first bilateral arm transplant, together with an innovative treatment to prevent rejection of the new limbs.
The Johns Hopkins University’s Institutional Review Board (IRB) has formally approved plans submitted by Johns Hopkins Medicine’s Department of Plastic and Reconstructive Surgery to begin performing facial transplants. The approval, granted in late July, allows the hospital’s facial transplantation team to begin accepting patients for this surgery – for the very first time.
A Johns Hopkins Children’s Center study of patients who received liver transplants from living donors has found that better outcomes need not come with a heftier price tag.
Johns Hopkins researchers say a program they developed that uses personal advocates and community networks to find organ donors for friends and loved ones who need kidney transplants resulted in success for nearly half of the participants in its trial run.
When Harvard University friends Sheryl Sandberg and Andrew M. Cameron, M.D., Ph.D., met up at their 20th college reunion last spring, they got to talking. Sandberg knew that Cameron, a transplant surgeon at Johns Hopkins, was passionate about solving the perennial problem of transplantation: the critical shortage of donated organs in the United States. And he knew that Sandberg, as chief operating officer of Facebook, had a way of easily reaching hundreds of millions of people.
Thousands more American senior citizens with kidney disease are good candidates for transplants and could get them if physicians would get past outdated medical biases and put them on transplant waiting lists, according to a new study by Johns Hopkins researchers.
Kidney disease patients treated at for-profit dialysis centers are 20 percent less likely to be informed about transplant options and referred for the potentially lifesaving operation than those at nonprofit centers, new Johns Hopkins research suggests.
Changing the organ donation process in this country from opt-in — by, say, checking a box on a driver’s license application— to opt-out, which presumes someone’s willingness to donate after death unless they explicitly object while alive, would not be likely to increase the donation rate in the United States, new Johns Hopkins research suggests.
White heart transplant patients under the age of 18 are more than twice as likely to be alive a decade after surgery as their African-American counterparts, new Johns Hopkins research suggests.
Kidney transplants performed using organs from live donors over the age of 70 are safe for the donors and lifesaving for the recipients, new Johns Hopkins research suggests. The study shines new light on a long-ignored potential source of additional organs that could address a profound national shortage.
Johns Hopkins researchers have developed a way to stimulate a rat’s stem cells after a liver transplant as a means of preventing rejection of the new organ without the need for lifelong immunosuppressant drugs. The need for anti-rejection medicines, which carry serious side effects, is a major obstacle to successful long-term transplant survival in people
For years, medical studies have reached the same conclusion: African-American patients do better on kidney dialysis than their white counterparts. But new Johns Hopkins research, published in the Journal of the American Medical Association, shows that younger blacks — those under the age of 50 — actually do much worse on dialysis than equally sick whites who undergo the same blood-filtering process.
A national transplant policy change designed to give African-American patients greater access to donor kidneys has sliced in half the racial disparities that have long characterized the allocation of lifesaving organs, new Johns Hopkins research suggests.
Hard-to-match kidney transplant candidates who receive a treatment designed to make their bodies more accepting of incompatible organs are twice as likely to survive eight years after transplant surgery as those who stay on dialysis for years awaiting compatible organs, new Johns Hopkins research finds.
Despite concerns that surgeon fatigue is leading to dangerous complications for patients and data showing worse outcomes for many patients who undergo surgery at night, new Johns Hopkins research suggests that — in the case of heart and lung transplants — time of day has no affect on patient survival.
Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.
Older, sicker heart-transplant recipients are significantly more likely to be alive a year after their operations if they have their transplants at hospitals that do a large number of them annually, new Johns Hopkins research suggests. These patients fare less well at low-volume centers, the research shows.
If Congress reversed its ban on allowing people with HIV to be organ donors after their death, roughly 500 HIV-positive patients with kidney or liver failure each year could get transplants within months, rather than the years they currently wait on the list, new Johns Hopkins research suggests.
As a response to a 2007 episode in which four patients in Chicago were transplanted with organs from a single donor unknowingly infected with HIV — the only such episode in 20 years — one-third of transplant surgeons in the United States “overreacted” and began routinely using fewer organs from high-risk donors, new research from Johns Hopkins finds.
Kidney transplants using organs from live donors work just as well if the kidneys are shipped — be it across town or across the country — as when the donors and recipients are operated on at the same hospital, new Johns Hopkins research suggests.
Only a small fraction of transplant centers nationwide are willing to accept and transplant deceased-donor kidneys that they perceive as less than perfect, leading to lengthy, organ-damaging delays as officials use a one-by-one approach to find a willing taker. Now, Johns Hopkins researchers have designed a formula they say can predict which donor kidneys are most likely to be caught in that process, a method that could potentially stop thousands of usable kidneys each year from being discarded because it took too long for them to be transplanted. Previous studies have shown such kidneys can extend the life of certain dialysis patients, if allocated and transplanted in a timely manner.
Transplant surgeons at Johns Hopkins who have reviewed the medical records of more than 20,000 heart transplant patients say that it is not simply racial differences, but rather flaws in the health care system, along with type of insurance and education levels, in addition to biological factors, that are likely the causes of disproportionately worse outcomes after heart transplantation in African Americans.
More than half of donor kidneys in the United State infected with hepatitis C are thrown away, despite the need among hepatitis C patients who may die waiting for an infection-free organ, Johns Hopkins research suggests.