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Medications for Excessive Sweating (Hyperhidrosis)

Typically, doctors at the Center for Sweat Disorders will recommend the use of topical or oral medications to begin treating hyperhidrosis. Of course, if your symptoms are intolerable, or you have already tried oral medications, our doctors may recommend other treatments as well.

Drying Topical Creams

One of the first-line therapies our doctors may prescribe is daily topical creams that dry the skin. Aluminum chloride or aluminum chloride hexahydrate are the most common of these creams.

Applied daily, usually at night, and then covered to encourage absorption, these creams can be very effective. However, some people find that they have uncomfortable side effects, including burning and skin reactions.

Oral Medications

Oral medications are known as systemic therapies, meaning they affect your entire body. These medications are called anticholinergics, which mean they cause a drying reaction in the body. They can be a good option for patients who sweat in multiple locations. There are some side effects, like dry mouth and dry eyes. Sometimes, after using these medications for a while, patients find they lose their effectiveness.

Learn more about other treatments for excessive sweating

Related Articles, Videos and Interviews 

Treatment Options: Read or Listen to this interview from WAMU 88.5 to learn more about treatment options and hear from patients who were treated for excessive sweating at Johns Hopkins.

No Sweat: How Surgery Changed the Life of a Man with Excessive Perspiration Read the article.

Do You Suffer from Excessive Sweating? Dr. Malcolm Brock explains excessive sweating and what treatment options are available for patients who suffer from hyperhidrosis. Watch the video.