Annette Jackson Lab

  • Research in the Annette Jackson Lab focuses on the characterization of HLA and non-HLA antibodies and their role in allograft rejection. We are investigating the mechanisms involved in keeping donor HLA-specific B cells quiescent in transplant recipients following desensitization and transplantation. We also study the development of quantitative measures of immune memory to aid in donor selection and individualization of immunosuppression. We are identifying the non-HLA targets of endothelial cell reactive antibodies to allow for improved detection of these antibodies and to decipher their role in allograft injury.

    Research Areas: blood disorders, allograft rejection, transplants, antibodies, HLA antibodies, immunosuppression

    Principal Investigator

    Annette Jackson, Ph.D.

    Department

    Medicine