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Engineering the Immune System

By merging the best of immunology and the best of engineering researches created a new field – immunoengineering. From enhancing tissue regeneration to preventing the body’s rejection of medical implants to boosting the immune system this brand new field brings new possibilities for improving cancer treatments.

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The Importance of Platelets - Kelly Metcalf Pate, D.V.M., Ph.D.

Dr. Kelly Metcalf Pate studies how platelets in the blood team together to stop bleeding and fight infection. Her team is studying whether a low platelet number impairs the body’s ability to defend itself from HIV.

Jiajia Zhang on her journey back to grad school.

Jiajia Zhang was a trained oncologist in China when she read news about former Vice President Joe Biden's visit to Johns Hopkins and the launch of the Bloomberg-Kimmel Institute for Cancer Immunotherapy. She decided to focus the rest of her career on research, and she was accepted into a master of public health program in the Johns Hopkins Bloomberg School of Public Health. 

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Highlights

Why Cancer Often Strikes Those with Healthy Lifestyles

Study provides evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer.

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Antibiotic Coating Prevents Orthopaedic Joint Infections in Animals

Researchers have designed a thin, biodegradable plastic coating for metal implants that can release multiple antibiotics to diminish the chance of such infections.

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New Protein Culprit Identified in Alzheimer’s

By removing a protein that appears to be elevated in both mice and humans, researchers were able to prevent animals from developing Alzheimer’s characteristic memory losses.

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How Randomness Helps Cancer Cells Thrive

By combining math and biology researchers added more evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA.

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Gene Therapy Offers Hope For People with Usher Syndrome

Results showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome.

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