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Clinical Trials

These trials are currently being conducted at the Johns Hopkins Department of Radiation Oncology and Molecular Radiation Sciences. If you would like to find out more about clinical trials and how they work, you can read about them on our About Clinical Trials page.

To learn more about trials being conducted at Johns Hopkins and how to enroll in a trial, contact:

Shirl DiPasquale, RN, MS, OCN
(For trials treating cancers of the breast, lung, and prostate)

Phone: 410-614-1598

Kelly Szajna, RN, BS
(For trials treating cancers of the central nervous system, breast, lung, and prostate)

Phone: 410-502-9242

Explore the full listing of cancer-related clinical trials at the Sidney Kimmel Cancer Center.

Open Radiation Oncology Clinical Trials

Z15111 - Exploratory Study of the CytoRADx System as a Biodosimeter


J14176 - Ultrasound System for Non-Invasive, Real-Time Monitoring of Abdominal Soft Tissue

Brain and Central Nervous System

J11120 - A phase II trial of low dose fractionated radiation therapy as a chemo-potentiator of salvage temozolomide for recurrent anaplastic astrocytoma and glioblastoma multiforme
J1439 - A Pilot Study Using Amide Proton Transfer (APT) Magnetic Resonance Imaging to Distinguish Tumor Bearing Cancerous Tissue from Normal Tissue in Patients with Glioma
J1426 - A Randomized Phase II Study of Subventricular Zone (SVZ) Irradiation Plus Temozolomide in Newly Diagnosed Glioblastoma Multiforme


J14106 - Non-invasive Detection of Cancer DNA in Blood and Urine


R0926 - A Phase II Protocol for Patients with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging


J11155 - Pre-Operative PARPi and Irradiation (POPI) in Women with an Incomplete Response to Neo-Adjuvant Chemotherapy for Breast Cancer
J13104 - A Randomized Phase II Study of Partial Breast Irradiation and Sequential vs. Concurrent Chemotherapy in Women with ER Negative Early Stage Breast Cancer (PBI 3.0)
J08130 - Cytokine Expression During Radiation Therapy for Breast Cancer
J1564 - The IDEA Study (Individualized Decisions for Endocrine therapy Alone): A prospective, single-arm cohort study of patients receiving endocrine therapy alone (without radiotherapy) after breast conserving surgery for early-stage, post-menopausal breast cancer patients whose tumors have favorable biologic features.

Head and Neck

J14191 - A Feasibility Study of the VibrentTM Smartphone App for Head & Neck Cancer Patients: Supporting Pain Management of Radiation-Induced Mucositis


J12127 - A Phase II Trial of Hippocampal-Sparing Prophylactic Cranial Irradiation (PCI) for Small Cell Lung Cancer (SCLC)


J12133 - Phase II Study of Post-Operative Stereotactic Radiosurgery for Solid Tumor Spine Metastases
J1367 - A Phase II Study of Hypofractionated Stereotactic Radiotherapy in the Treatment of Metastatic Pediatric Sarcomas of Bony Sites


J1273 - Phase II Study to Evaluate Stereotactic Body Radiation Therapy For Palliative Management of Unresectable Recurrent or Residual Pancreatic or Periampullary Adenocarcinoma
J15237 - A Phase II Study of GM-CSF secreting allogeneic pancreatic cancer vaccine in combination with PD-1 Blockade Antibody (Pembrolizumab) and Stereotactic Body Radiation Therapy (SBRT) for the Treatment of Patients with Locally Advanced Adenocarcinoma of the Pancreas


J0859 - Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate 
J1192 - A Randomized Controlled Trial of Prostatak as Adjuvant to Up-Front Radiation Therapy for Localized Prostate Cancer
J11143 - Multiparametric MRI for assessing radiotherapy treatment response of prostate cancer
J11157 - Stereotactic Body Radiation Therapy and Short-Term Androgen Ablation for Intermediate-Risk, Localized, Adenocarcinoma of the Prostate
J13164 - Pilot Study of Dynamic Intraoperative Dosimetry for Prostate Brachytherapy using Registered Fluoroscopy and Ultrasound (RadVision)
J1454 - Phase II Randomized Placebo-Controlled Double-Blind Study of Salvage Radiation Therapy (SRT) Plus Placebo Versus SRT Plus Enzalutamide in Men with High-Risk PSA-Recurrent Prostate Cancer after Radical Prostatectomy
J15139 - A Qualitative Study to Explore Patients’ Experience of Pancreatic Cancer and Evaluate Relevant Patient-Reported Outcome Measures for Clinical Trials
J15180 - Phase II Randomized Observation versus Stereotactic Ablative RadiatIon for OLigometastatic Prostate CancEr (ORIOLE) Trial
J14187 - REASSURE - Radium-223 alpha Emitter Agent in Safety Study in mCRPC population for long-term Evaluation
J15203 - Pilot Biomarker Study of Stereotactic Body Radiation Therapy for Prostate Cancer Oligometastases


J1360 - Chemoradiation OR Brachytherapy for RECTal cancer


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We enroll patients in clinical trials every day. Find out what’s available for you.

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