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Clinical Trials

These trials are currently being conducted at the Johns Hopkins Department of Radiation Oncology and Molecular Radiation Sciences. If you would like to find out more about clinical trials and how they work, you can read about them on our About Clinical Trials page.

To learn more about trials being conducted at Johns Hopkins and how to enroll in a trial, contact:

Shirl DiPasquale, RN, MS, OCN
(For trials treating cancers of the breast, lung, and prostate)

Phone: 410-614-1598

Kelly Szajna, RN, BS
(For trials treating cancers of the central nervous system, breast, lung, and prostate)

Phone: 410-502-9242

Explore the full listing of cancer-related clinical trials at the Sidney Kimmel Cancer Center.

Open Radiation Oncology Clinical Trials

Brain and Central Nervous System

J11120 - A phase II trial of low dose fractionated radiation therapy as a chemo-potentiator of salvage temozolomide for recurrent anaplastic astrocytoma and glioblastoma multiforme


R0926 - A Phase II Protocol for Patients with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging


J08130 - Cytokine Expression During Radiation Therapy for Breast Cancer
J11155 - Pre-Operative PARPi and Irradiation (POPI) in Women with an Incomplete Response to Neo-Adjuvant Chemotherapy for Breast Cancer
J13104 - A Randomized Phase II Study of Partial Breast Irradiation and Sequential vs. Concurrent Chemotherapy in Women with ER Negative Early Stage Breast Cancer (PBI 3.0)

Head & Neck

J0988 - A Phase II Study of Treatment De-Intensification in Favorable Squamous Cell Carcinoma of the Oropharynx


R0937 - Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extra-Cranial Irradiation for Extensive Disease Small Cell Lung Cancer (ED-SCLC) RTOG0937
J12127 - A Phase II Trial of Hippocampal-Sparing Prophylactic Cranial Irradiation (PCI) for Small Cell Lung Cancer (SCLC)
J1370 - Evaluation of Tumor Motion Management Strategies in Radiotherapy Using 4D-MRI


J12133 - Phase II Study of Post-Operative Stereotactic Radiosurgery for Solid Tumor Spine Metastases
J12137 - A Phase I-II Study: Evaluation of Stereotactic Body Radiation Therapy Concurrent with Nelfinavir for Oligometastases
J1367 - A Phase II Study of Hypofractionated Stereotactic Radiotherapy in the Treatment of Metastatic Pediatric Sarcomas of Bony Sites


J1273 - Phase II Study to Evaluate Stereotactic Body Radiation Therapy For Palliative Management of Unresectable Recurrent or Residual Pancreatic or Periampullary Adenocarcinoma


J0859 - Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate 
J1192 - A Randomized Controlled Trial of Prostatak as Adjuvant to Up-Front Radiation Therapy for Localized Prostate Cancer
J11143 - Multiparametric MRI for assessing radiotherapy treatment response of prostate cancer
J11157 - Stereotactic Body Radiation Therapy and Short-Term Androgen Ablation for Intermediate-Risk, Localized, Adenocarcinoma of the Prostate
J13164 - Pilot Study of Dynamic Intraoperative Dosimetry for Prostate Brachytherapy using Registered Fluoroscopy and Ultrasound (RadVision)


J0977 - Phase II study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer
J1360 - Chemoradiation OR Brachytherapy for RECTal cancer


Participate in a Clinical Trial

We enroll patients in clinical trials every day. Find out what’s available for you.

Apply for Training

We offer residency programs for radiation oncology and medical physics and a radiation therapy program for therapists. Get the details.

Sidney Kimmel Comprehensive Cancer Center

The Center leads the world in the diagnosis and treatment of cancer. Read more.

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International +1-410-614-6424



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