Dr. Cyrus Engineer works for the World Health Organization based in Geneva and is associated with the Patient Safety Program within the Information, Evidence and Research cluster. Working for the first Global Patient Safety Challenge, Cyrus led the Save Lives: Clean Your Hands initiative that aimed to heighten awareness on the issue of health care associated infections and raise the profile of hand hygiene among health care professionals globally. 

He directed and led a global campaign from WHO headquarters in Geneva.Over 5801 hospitals from 125 countries signed up to this initiative and endorsed their support. Cyrus also serves as a faculty and co-teaches courses on patient safety, problem solving in public health and quality assurance in developing countries at the Johns Hopkins University's Bloomberg School of Public Health in Baltimore.

Cyrus is currently the Manager of WHO's patient safety project at the Johns Hopkins University School of Medicine in Baltimore. From here he continues to work on WHO's Patient Safety projects in association with Dr. Peter Pronovost's Quality and Safety Research Group. Planned areas of work include programme evaluation of work streams originating at WHO headquarters, reducing blood stream infections in other countries and continuing on the hand hygiene initiative.

Cyrus began his health care career in hospital administration at the P.D. Hinduja and Breach Candy Hospitals in Mumbai after getting his Masters degree from the Tata Institute of Social Sciences. He led one of the first hospitals in India to become ISO certified when few formal accreditation standards or programmes existed. His interests in patient safety and quality led him to Johns Hopkins University where he obtained his second Masters followed by a Doctorate degree in Public Health.