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OACIS: Publications

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Mechanical Ventilation/Acute Respiratory Distress Syndrome

Hager DN, Dinglas VD, Subhas S, Rowden AM, Neufeld KJ, Bienvenu OJ, Touradji P, Colantuoni E, Reddy DRS, Brower RG, Needham DM. Reducing deep sedation and delirium in acute lung injury patients: a quality improvement project. Critical Care Medicine. 2013 In press

Needham DM, Colantuoni E, Mendez-Tellez PA, Dinglas VD, Sevransky JE, Dennison Himmelfarb CR, Desai SV, Shanholtz C, Brower RG, Pronovost PJ. Lung protective mechanical ventilation and 2-year survival for acute lung injury: a prospective cohort study. BMJ. 2012;344:e2124. Free Full Text Version

Bienvenu OJ, Colantuoni E, Mendez-Tellez PA, Dinglas VD, Shanholz C, Husain N, Dennison CR, Herridge MS, Pronovost PJ, Needham DM. Depressive symptoms and impaired physical function after acute lung injury: a 2-year longitudinal study. American Journal of Respiratory and Critical Care Medicine. 2012;185:517-524.

Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Vincent J-L, Bersten A, Needham D, Persenti A. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012; 307(23):2526-2533.

Damluji A, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Fan E, Shanholtz C, Wojnar M, Pronovost PJ, Needham DM. Short-term mortality prediction for acute lung injury patients: external validation of the ARDSNet prediction model. Critical Care Medicine. 2011;36:1023-1028.

Wang W, Scharfstein D, Wang C, Daniels M, Needham D, Brower R. Estimating the causal effect of low tidal volume ventilation on survival in patients with acute lung injury. Journal of the Royal Statistical Society: Series C (Applied Statistics). 2011;60:475-496.

Dasenbrook EC, Needham DM, Brower RG, Fan E. Higher positive end-expiratory pressure in patients with acute lung injury: a systematic review and meta-analysis. Respiratory Care. 2011;56:568-575.

Spragg RG, Bernard GR, Checkley W, Curtis JR, Gajic O, Guyatt G, Hall J, Israel E, Jain M, Needham DM, Randolph AG, Rubenfeld GD, Schoenfeld D, Thompson BT, Ware LB, Young D, Harabin AL. Beyond mortality: future clinical research in acute lung injury: an NHLBI workshop report. American Journal of Respiratory and Critical Care Medicine; 2010;181:1121-1127.

Mendez-Tellez P, Damluji A, Ammerman D, Colantuoni E, Fan E, Sevransky JE, Shanholtz C, Gallant JE, Pronovost PJ, Needham DM. Human immunodeficiency virus infection and hospital mortality in acute lung injury patients. Critical Care Medicine. 2010;38:1530-1535.

Sevransky J, Martin GS, Shanholtz C, Mendez-Tellez P, Pronovost PJ, Brower R, Needham DM. Mortality in sepsis versus non-sepsis induced acute lung injury. Critical Care. 2009;13:R150

Murphy D, Howard D, Muriithi A, Mendez-Tellez P, Sevransky J, Shanholtz C, Netzer G, Pronovost PJ, Needham DM. Red blood cell transfusion practices in acute lung injury: what do patient factors contribute? Critical Care Medicine. 2009; 37:1935-1940.

Umoh NJ, Fan E, Mendez-Tellez PA, Sevransky JE, Dennison CR, Shanholtz C, Pronovost PJ, Needham DM. Patient and ICU organizational factors associated with low tidal volume ventilation in acute lung injury. Critical Care Medicine. 2008; 36:1463-1468.

Fan E, Khatri P, Mendez-Tellez PA, Shanholtz S, Needham DM. Sedation and analgesia usage with airway pressure release and assist-control ventilation for acute lung injury. Journal of Intensive Care Medicine. 2008;23:376-383.

Sevransky J, Martin GS, Mendez-Tellez P, Shanholtz C, Brower R, Pronovost PJ, Needham DM. Pulmonary vs. non-pulmonary sepsis and mortality in acute lung injury. Chest. 2008;134 534-538

Dennison CR, Mendez-Tellez PA, Wang W, Pronovost PJ, Needham DM. Barriers to low tidal volume ventilation in acute respiratory distress syndrome: survey development, validation and results. Critical Care Medicine. 2007;35:2747-2754

Fan E, Needham DM, Stewart TE. Ventilatory management of acute lung injury and acute respiratory distress syndrome. Journal of the American Medical Association (JAMA). 2005;294:2889-2896.

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Psychiatric Issues in Critical Care

Hager DN, Dinglas VD, Subhas S, Rowden AM, Neufeld KJ, Bienvenu OJ, Touradji P, Colantuoni E, Reddy DRS, Brower RG, Needham DM. Reducing deep sedation and delirium in acute lung injury patients: a quality improvement project. Critical Care Medicine. 2013 In press

Law TJ, Leistikow NA, Hoofring L, Krumm SK, Neufeld KJ, Needham DM. A survey of nurses' perceptions of the Intensive Care Delirium Screening Checklist. Dyanmics. In press.

Kamdar BB, King LM, Collop NA, Sakamuri S, Colantuoni E, Neufeld KJ, Bienvenu OJ, Rowden AM, Touradji P, Brower RG, Needham DM. The effect of a quality improvement intervention on perceived sleep quality and cognition in a medical ICU. Critical Care Medicine. In press.

Bienvenu OJ, Neufeld K, Needham DM. Treatment of four psychiatric emergencies Psychiatric Issues in Critical Care in the ICU. Critical Care Medicine. 2012;40:2662-2670.

Neufeld K, Huberman A, Needham DM. Chapter 79 Delirium. In: McKean SC, Ross JJ, Dressler DD, Brotman D (Eds). Principles and Practice of Hospital Medicine. Burr Ridge, IL, McGraw-Hill. March 2012.

Hopkins RO, Suchyta MR, Farrer TJ, Needham DM. Improving post-ICU neuropsychiatric outcomes: understanding cognitive effects of physical activity. American Journal of Respiratory and Critical Care Medicine. 2012 Dec 15;186(12):1220-8. doi: 10.1164/rccm.201206-1022CP. Epub 2012 Oct 11.

Bienvenu OJ, Colantuoni E, Mendez-Tellez PA, Dinglas VD, Shanholz C, Husain N, Dennison CR, Herridge MS, Pronovost PJ, Needham DM. Depressive symptoms and impaired physical function after acute lung injury: a 2-year longitudinal study. American Journal of Respiratory and Critical Care Medicine. 2012;185:517-524.

Desai SV, Law TJ, Bienvenu OJ, Needham DM. Psychiatric long-term complications of intensive care unit survivors. Critical Care Medicine 2011;39:2790.

Neufeld KJ, Bienvenu OJ, Rosenberg PB, Mears SC, Lee HB, Kamdar BB, Sieber FE, Krumm SK, Walston JD, Hager DN, Touradji P, Needham DM. Johns Hopkins Delirium Consortium: One model for collaborating across disciplines and departments for delirium prevention and treatment. Journal of the American Geriatrics Society. 2011;59:S244-S248.

Dowdy DW, Bienvenu OJ, Dinglas V, Mendez-Tellez PA, Sevransky J, Shanholtz C, Needham DM. Are intensive care factors associated with depressive symptoms six months after acute lung injury? Critical Care Medicine. 2009;37:1702-1707.

Davydow DS, Gifford JM, Desai SV, Bienvenu OJ, Needham DM. Depression in general intensive care unit survivors: a systematic review. Intensive Care Medicine. 2009; 35:796-809.

Davydow DS, Desai SV, Needham DM, Bienvenu OJ. Psychiatric morbidity in survivors of the acute respiratory distress syndrome: a systematic review. Psychosomatic Medicine. 2008;70:512-519.

Dowdy DW, Dinglas V, Mendez-Tellez PA, Bienvenu OJ, Sevransky J, Dennison CR, Shanholtz C, Needham DM. Intensive care unit hypoglycemia predicts depression during early recovery from acute lung injury. Critical Care Medicine. 2008;36:2726-2733.

Davydow DS, Gifford JM, Desai SV, Needham DM, Bienvenu OJ. Posttraumatic stress disorder in general intensive care unit survivors: a systematic review. General Hospital Psychiatry. 2008;30:421-434.

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Physical Function and Rehabilitation in the ICU

Lord RK, Mayhew CR, Korupolu R, Mantheiy EC, Friedman MA, Palmer JB, Needham DM. ICU early physical rehabilitation programs: financial modeling of cost savings. Critical Care Medicine. In press.

  • ICUs with early physical rehabilitation programs have demonstrated decreases in length of stay, but formal financial analyses are often needed to justify the financial investment in these programs. This article and the associated Excel model can assist in conducting such financial analyses customized to a hospital’s unique situation. Model (Excel 2007 or later) / User Guide

Dinglas VD, Colantuoni E, Ciesla N, Mendez-Tellez PA, Shanholtz C, Needham DM. Occupational therapy for acute lung injury patients: factors associated with time to first intervention in the intensive care unit. American Journal of Occupational Therapy. 2012. In Press.

Kamdar BB, Needham, DM, Collop NA. Sleep deprivation in critical illness: its role in physical and psychological recovery. Journal of Intensive Care Medicine; in press.

Rahimi RA, Skrzat J, Reddy DRS, Zanni JM, Fan E, Stephens RS, Needham DM. Physical Rehabilitation of Intensive Care Patients Requiring Extracorporeal Membrane Oxygenation: A Small Case Series. Physical Therapy 2012 Dec 20..

Needham DM, Kamdar KB, Stevenson JE. Rehabilitation of mind and body after ICU discharge: A step closer to recovery. Critical Care Medicine. 2012. 40:1340-1341.

Needham DM, Wunsch H, Harvey MA. Post-intensive care syndrome (PICS): a new and evolving definition that calls for continued global collaboration. Critical Care Medicine 2012;40:2743.

Hopkins RO, Suchyta MR, Farrer TJ, Needham DM. Improving post-ICU neuropsychiatric outcomes: understanding cognitive effects of physical activity. American Journal of Respiratory and Critical Care Medicine. 2012 Dec 15;186(12):1220-8. doi: 10.1164/rccm.201206-1022CP. Epub 2012 Oct 11.

Gosselink R, Needham D, Hermans G. ICU-based rehabilitation and its appropriate metrics. Current Opinion in Critical Care. 2012;18:533-539.

Mendez-Tellez PA, Needham DM. Early physical rehabilitation in the ICU and ventilator liberation. Respiratory Care. 2012;571663-1669.

Kho ME, Truong AD, Brower RG, Palmer JB, Fan E, Zanni JM, Ciesla ND, Feldman DR, Korupolu R, Needham DM. Neuromuscular electrical stimulation for ICU-acquired weakness: Protocol and methodological implications for a randomized, sham-controlled phase II trial. Physical Therapy Journal. 2012 Dec;92(12):1564-79. doi: 10.2522/ptj.20110437. Epub 2012 Mar 15.

Mendez-Tellez PA, Nusr R, Feldman D, Needham DM. Early physical rehabilitation in the ICU: a review for the neurointensivist. Neurohospitalist. 2: 96-105 (2012).

Kho ME, Damluji A, Zanni JM, Needham DM. Feasibility and observed safety of interactive videogames for physical rehabilitation in the intensive care unit: a case series. Journal of Critical Care. 2012;27:291.e1-219.e6.

Fan E, Gifford JM, Chandolu S, Colantuoni E, Pronovost PJ, Needham DM. The functional comorbidity index had high inter-rater reliability in patients with acute lung injury. BMC Anesthesiology. 2012; 12(1):21.

Ciesla, N., Dinglas, V., Fan, E., Kho, M., Kuramoto, J., Needham, D., Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients http://www.jove.com/details.stp?id=2632 doi: 10.3791/2632. Journal of Visualized Experiments. 50 (2011).

Korupolu R, Gifford JM, Zanni JM, Truong A, Vajrala G, Lepre S, Needham DM. Early mobilization in the intensive care unit: safety, feasibility and benefits. In Esquinas AM (Ed). Applied Technologies in Pulmonary Medicine. Basel, Karger. 2011.

Needham DM, Feldman DR, Kho ME. The functional costs of ICU survivorship: collaborating to improve post-ICU disability. American Journal of Respiratory & Critical Care Medicine. 2011;183:962-964.

Dinglas VD, Gellar J, Colantuoni E, Stan VA, Mendez-Tellez PA, Pronovost PJ, Needham DM. Does ICU severity of illness influence recall of baseline physical function? Journal of Critical Care.2011; 26: 634.e1-634.e7.

Needham DM, Feldman DR, Kho ME. The functional costs of ICU survivorship: collaborating to improve post-ICU disability. American Journal of Respiratory & Critical Care Medicine. 2011;183:962-964

Zanni JM, Korupolu R, Fan E, Pradhan P, Janjua K, Palmer JB, Brower RG, Needham DM. Rehabilitation therapy and outcomes in acute respiratory failure: an observational pilot project. Journal of Critical Care. 2010;25:254-262.

Needham DM, Korupolu R, Zanni JM, Pradhan P, Conlantuoni E, Palmer JB, Brower RG, Fan E. Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project. Archives of Physical Medicine and Rehabilitation. 2010;91:536-542.

Korupolu R, Zanni J, Fan E, Butler, M, Needham DM. Early mobilization of intensive care unit patient: the challenges of morbid obesity and multi-organ failure. BMJ Case Reports 2010; doi:10.1136/bcr.09.2009.2257.

Fan E, Ciesla ND, Truong AD, Bhoopathi V, Zeger SL, Needham DM Inter-rater reliability of manual muscle strength testing in ICU survivors and simulated patients. Intensive Care Medicine. 2010,36:1038-1043. PMCID: PMC2891143

Kho ME, Korupolu R, Needham DM. Early mobilization of critically ill patients: required resources. ICU Management. 2010;10(1)36-37.

Zanni, JM, Needham, DM. Promoting early mobility and rehabilitation in the intensive care unit. PT in Motion. 2010:May:32-38.

Needham DM, Korupolu R. Rehabilitation quality improvement in an intensive care unit setting: implementation of a quality improvement model. Topics in Stroke Rehabilitation; 2010;17:271-281.

Needham DM, Truong AD, Fan E. Technology to enhance physical rehabilitation of critically ill patient. Critical Care Medicine. 2009;37(Suppl):S436-S441

Stevens RD, Marshall SA, Cornblath DR, Hoke A, Needham DM, de Jonghe B, Ali NA, Sharshar T. A framework for diagnosing and classifying intensive care unit-acquired weakness. Critical Care Medicine. 2009; 37(Suppl):S299-S308.

Fan E, Zanni JM, Dennison CR, Lepre SJ, Needham DM. Critical illness neuromyopathy and muscle weakness in the intensive care unit. AACN Advanced Critical Care. 2009;20:243-253.

Kho ME, Korupolu R, Needham DM. Early mobilization of critically ill patients: feasibility and benefits. ICU Management. 2009;9(4)4:31-32.

Korupolu R, Chandolu S, Needham DM. Early mobilization of critically ill patients: screening and safety issues. ICU Management. 2009;9:27-30.

Korupolu R, Gifford JM, Needham DM. Early mobilization of critically ill patients: reducing neuromuscular complications after intensive care. Contemporary Critical Care. 2009;6:1-12.

Primus R, Korupolu R, Needham DM. Early mobilization of critically ill obese patients. ICU Management. 2009;9(4):19.

Truong AD, Fan E, Brower RG, Needham DM. Mobilizing patients in the intensive care unit: from pathophysiology to clinical trials. Critical Care. 2009;13:216

Needham DM, Chandolu S, Zanni J. Interruption of sedation for early rehabilitation improves outcomes in ventilated, critically ill adults. Australian Journal of Physiotherapy. 2009;55:210.

Needham DM. Mobilizing patients in the intensive care unit: back to the future. Journal of the American Medical Association (JAMA). 2008; 300:1685-1690.

Fan E, Needham DM. Mechanical ventilation and disuse atrophy of the diaphragm. New England Journal of Medicine. 2008; 359:90-91.

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Quality Improvement

Kamdar BB, King LM, Collop NA, Sakamuri S, Colantuoni E, Neufeld KJ, Bienvenu OJ, Rowden AM, Touradji P, Brower RG, Needham DM. The effect of a quality improvement intervention on perceived sleep quality and cognition in a medical ICU. Critical Care Medicine. 2013; 41:800-809Checklist for Sleep Quality Improvement Project in Johns Hopkins MICU

Hager DN, Dinglas VD, Subhas S, Rowden AM, Neufeld KJ, Bienvenu OJ, Touradji P, Colantuoni E, Reddy DRS, Brower RG, Needham DM. Reducing deep sedation and delirium in acute lung injury patients: a quality improvement project. Critical Care Medicine. 2013 In press

Kamdar BB, Shah PA, King LM, Kho ME, Zhou X, Colantuoni E, Collop NA, Needham DM. Patient-Nurse interrater reliability and agreement of the Richards-Campbell Sleep Questionnaire in a Medical Intensive Care Unit. American Journal of Critical Care. In press.

Berenholtz SM, Needham DM, Lubomski LH, Goeschel CA, Pronovost PJ. Improving the quality of quality improvement studies. Joint Commission Journal on Quality and Patient Safety. 2011. In press.

Lipitz-Snyderman A. Needham DM, Colantuoni E, Goeschel CA, Marsteller JA, Thompson DA Berenholtz SM, Lubomski LH, Watson S, Pronovost PJ. How long can intensive care units maintain zero central line-associated bloodstream infections? Archives of Internal Medicine. 2011;171:856-858.

Lipitz-Snyderman A, Steinwachs D, Needham DM, Colantuoni E, Morlock LL, Pronovost, PJ. Impact of a statewide intensive care unit quality improvement initiative on hospital mortality and length of stay: retrospective comparative analysis. British Medical Journal. 2011;342:d219.

Berenholtz SM, Pham JC, Thompson DA, Needham D, Lubomski L, Hyzy R, Welsh R, Cosgrove SE, Sexton B, Colantuoni E, Watson SR, Goeschel CA, Pronovost PJ. An Intervention to reduce ventilator-associated pneumonia in the ICU. Infection Control and Hospital Epidemiology. 2011;32:305-3142011.

Waters HR, Korn R, Colantuoni E, Berenholtz SM, Goeschel CA, Needham D, Pham JC, Lipitz A, Watson SR, Posa P, Pronovost PJ. The Business Case for Quality: Economic Analysis of the Michigan KeystonePatient Safety Program in ICUs. American Journal of Medical Quality. 2011;26:333-339.

Needham DM. Patient safety, quality of care and knowledge translation in the ICU. Respiratory Care; 2010;55:922-928.

Pronovost PJ, Murphy D, Needham DM. The science of translating research into practice in intensive care. American Journal of Respiratory and Critical Care Medicine. 2010;182:1463-1464.

Needham DM, Sinopoli DJ, Dinglas VD, Berenholtz SM, Korupolu R, Watson SR, Lumbomski L, Goeschel C, Pronovost PJ. Improving data quality control in quality improvement projects. International Journal for Quality in Health Care. 2009; 21:145-150.

Pronovost PJ, Berenholtz SM, Needham DM. Translating evidence into practice: a model for large-scale knowledge translation. BMJ. 2008;337:a1714.

Fan E, Needham DM. The science of quality improvement. JAMA. 2008; 300:390-1.

Pronovost PJ, Needham DM, Berenholtz S, et al. Reducing catheter-related blood stream infections in Michigan intensive care units. New England Journal of Medicine. 2006;355:2725-2732

Pronovost PJ, Berenholz S, Goeschel CA, Needham DM, Sexton BJ, Thompson DA, Lubomski LH, Marsteller J, Makary M, Hunt E. Creating high reliability in healthcare organizations. Health Services Research. 2006;41:1599-1617.

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Long-Term ICU Outcomes Studies

Needham DM, Dinglas VD, Bienvenu OJ, Colantuoni E, Wozniak AW, Rice TW, Hopkins RO. One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomised trial. BMJ 2013;346:f1532. Free Full Text Version

Bienvenu OJ, Colantuoni E, Mendez-Tellez PA, Dinglas VD, Shanholz C, Husain N, Dennison CR, Herridge MS, Pronovost PJ, Needham DM. Depressive symptoms and impaired physical function after acute lung injury: a 2-year longitudinal study. American Journal of Respiratory and Critical Care Medicine. 2012;185:517-524.

Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, Zawistowski C, Bemis-Dougherty A, Berney SC, Bienvenu OJ, Brady SL, Brodsky MB, Denehy L, Elliott D, Flatley C, Harabin AL, Jones C, Louis D, Meltzer W, Muldoon SR, Palmer JB, Perme C, Robinson M, Schmidt DM, Scruth E, Spill GR, Storey P, Render M, Votto J, Harvey MA. Improving long-term outcomes after discharge from ICU: report from a stakeholders’ conference. Critical Care Medicine. 2011; In press.

Desai SV, Law TJ, Bienvenu OJ, Needham DM. Psychiatric long-term complications of intensive care unit survivors. Critical Care Medicine 2011;39:2790.

Desai SD, Law TJ, Needham DM. Long-term complications of critical care. Critical Care Medicine. 2011;39:371-379.

Al Damluji A, Sepulveda KA, Needham DM. Understanding and improving long-term sequelae of ARDS. The Journal of Respiratory Diseases. 2008;29:198-199.

Damluji A, Siddiqi F, Dinglas VD, Needham DM. Long-term outcomes after acute lung injury/acute respiratory distress syndrome. US Respiratory Disease. 2008;4:89-92.

Needham DM, Wang W, Desai SV, Mendez-Tellez PA, Dennison CR, Sevransky J, Shanholtz C, Ciesla N, Spillman K, Pronovost PJ. ICU exposures for long-term outcomes research: development and description of exposures for 150 ALI patients. Journal of Critical Care. 2007; 22:275-284.

Needham DM, Dennison CR, Dowdy DW, Mendez-Tellez PA, Ciesla N, Desai SV, Sevransky J, Shanholtz C, Scharfstein D, Herridge MS, Pronovost PJ. The Improving Care of Acute Lung Injury Patients (ICAP) study: study design and methods. Critical Care. 2006;10:R9.

Desai SV, Boucher K, Fan E, Needham DM. Long-term outcomes after acute lung injury. Contemporary Critical Care. 2006;4:1-10.

Dowdy DW, Eid MP, Mendez-Tellez PA, Dennison CR, Herridge MS, Pronovost PJ, Needham DM. Meta-analysis: quality of life in adult survivors of acute respiratory distress syndrome. Intensive Care Medicine. 2006;32:1115-1124.

Dowdy DW, Needham DM, Mendez-Tellez P, Herridge MS, Pronovost PJ. Studying outcomes of intensive care unit survivors: the role of the cohort study. Intensive Care Medicine. 2005;31:914-921.

Needham DM, Dowdy DW, Mendez-Tellez P, Herridge MS, Pronovost PJ. Studying the outcomes of intensive care unit survivors: measuring exposures and outcomes. Intensive Care Medicine. 2005;31:1153-1160.

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Research Screening, Patient Retention and Contact

Chen K, Colantuoni E, Siddiqi F, Dinglas VD, Sepulveda KA, Fan E, Pronovost P, Needham DM. Repeated attempts using different strategies are important for timely contact with study participants. Journal of Clinical Epidemiology. 2011;64:1144-1151. PMCID: PMC3116960 NIHMS 236511 Article

Neufeld KJ, Hayat MJ, Coughlin JM, Huberman AL, Leistikow NA, Krumm SJ, Needham DM, Evaluation of two intensive care delirium screening tools for non-critically ill hospitalized oncology patients. Psychosomatics. 2011;52:133–140.

Fan E, Shahid S, Kondreddi VP, Bienvenu OJ, Mendez-Tellez PA, Pronovost PJ, Needham DM. Informed consent in the critically ill: a 2-step approach incorporating delirium screening. Critical Care Medicine. 2008;36:94-99.

Robinson KA, Dennison CR, Wayman DM, Pronovost PJ, Needham DM. Systematic review identifies number of strategies important for retaining study participants. Journal of Clinical Epidemiology. 2007;60:757-765.

Tansey CM, Matte AL, Needham DM, Herridge MS. Review of participant retention strategies in longitudinal studies of intensive care survivors. Intensive Care Medicine. 2007;33:2051:2057.

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Systematic Reviews/Meta-analyses

Search Builder 1.0 is a tool using Microsoft Excel® that composes search strategy text strings based on user-defined search terms and preferences. The search strategy text strings can easily be copied and pasted into the PubMed (MEDLINE) and Embase search engines. Search Builder 1.0 also is a convenient tool to archive and share search strategies. Created by: Biren B. Kamdar, MD, MBA, MHS

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Dasenbrook EC, Needham DM, Brower RG, Fan E. Higher positive end-expiratory pressure in patients with acute lung injury: a systematic review and meta-analysis. Respiratory Care. 2011;56:568-575.

Winters BD, Eberlein M, Leung J, Needham DM, Pronovost PJ, Sevransky JE. Long term mortality and quality of life in sepsis: a systematic review. Critical Care Medicine. 2010, 38:1276-1283.

Hogue CW, Stearns J, Colantuoni E, Robinson KA, Strierer T, Mitter N, Pronovost PJ, Needham DM. The impact of obesity on outcomes: A meta-analysis. Intensive Care Medicine. 2009; 35:1152-1170.

Davydow DS, Gifford JM, Desai SV, Bienvenu OJ, Needham DM. Depression in general intensive care unit survivors: a systematic review. Intensive Care Medicine. 2009; 35:796-809.

Davydow DS, Desai SV, Needham DM, Bienvenu OJ. Psychiatric morbidity in survivors of the acute respiratory distress syndrome: a systematic review. Psychosomatic Medicine. 2008;70:512-519.

Davydow DS, Gifford JM, Desai SV, Needham DM, Bienvenu OJ. Posttraumatic stress disorder in general intensive care unit survivors: a systematic review. General Hospital Psychiatry. 2008;30:421-434

Robinson KA, Dennison CR, Wayman DM, Pronovost PJ, Needham DM. Systematic review identifies number of strategies important for retaining study participants. Journal of Clinical Epidemiology. 2007;60:757-765.

Sevransky J, Nour S, Needham DM, Hollenberg S, Pronovost P, Sulsa GM. Hemodynamic goals in randomized clinical trials in sepsis: A systematic review of the literature. Critical Care. 2007;11:R67.

Stevens RD, Dowdy DW, Michaels R, Mendez-Tellez PA, Pronovost PJ, Needham DM. Neuromuscular dysfunction acquired in critical illness: a systematic review. Intensive Care Medicine. 2007; 33:1876-1891.

Tansey CM, Matte AL, Needham DM, Herridge MS.Review of participant retention strategies in longitudinal studies of intensive care survivors.Intensive Care Medicine. 2007;33:2051-2057.

Needham DM, Desai SV, Robinson KA. Critically appraise before you believe: the quality of meta-analyses is critical care medicine. Critical Care Medicine. 2007;35:666-667.

Dowdy DW, Eid MP, Mendez-Tellez PA, Dennison CR, Herridge MS, Pronovost PJ, Needham DM. Meta-analysis: quality of life in adult survivors of acute respiratory distress syndrome. Intensive Care Medicine. 2006;32:1115-1124.

Dowdy DW, Needham DM, Mendez-Tellez P, Herridge MS, Pronovost PJ. Studying outcomes of intensive care unit survivors: the role of the cohort study. Intensive Care Medicine. 2005;31:914-921.

Dowdy DW, Eid MP, Sedrakyan A, Mendez-Tellez PA, Pronovost PJ, Herridge MS, Needham DM. Quality of life in adult survivors of critical illness: A systematic review of the literature. Intensive Care Medicine. 2005; 31:611-620.

Needham DM, Scales DC, Laupacis A, Pronovost PJ. A systematic review of the Charlson Comorbidity Index using Canadian administrative databases: a perspective on risk adjustment in critical care research. Journal of Critical Care. 2005;20:12-19.

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Other Topics

Dinglas VD, Gifford JM, Husain N, Colantuoni E, Needham DM. Quality of life before intensive care using EQ-5D: patient versus proxy responses. Critical Care Medicine. 2013 Jan;41(1):9-14.

Fan E, Gifford JM, Chandolu S, Colantuoni E, Pronovost PJ, Needham DM. The functional comorbidity index had high inter-rater reliability in patients with acute lung injury. BMC Anesthesiology. 2012; 12(1):21.

O’Brien JM, Needham DM. Towards a better understanding of body mass index and patient outcomes. Anesthesia & Analgesia. 2011;112:8-10.

Gifford JM, Husain N, Dinglas VD, Colantuoni E, Needham DM. Baseline quality of life before intensive care: a comparison of patient versus proxy responses. Critical Care Medicine. 2010;38:855-860

Hogue CW, Stearns J, Colantuoni E, Robinson KA, Strierer T, Mitter N, Pronovost PJ, Needham DM. The impact of obesity on outcomes: A meta-analysis. Intensive Care Medicine. 2009; 35:1152-1170.

Needham DM, Pronovost PJ. The importance of understanding the costs of critical care and mechanical ventilation. Critical Care Medicine. 2005;33:1434-1435.

Needham DM, Pronovost PJ. Affordable health care. Critical Care Medicine. 2004; 32:2564


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