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Research Publications

Obsessive-Compulsive Disorder Program

Research Articles | Review Articles | Book Chapters

RESEARCH ARTICLES

1.  Nestadt G, Samuels JF, Romanoski AJ, Folstein MF, McHugh PR. Obsessions and compulsions in the community.  Acta Psychiatrica Scandinavica 1994;  89:219-224.

2. Nestadt G, Bienvenu OJ, Cai G, Samuels J, Eaton WW.  Incidence of obsessive-compulsive disorder in adults.  Journal of Nervous and Mental Disease 1998; 186:401-406.

3. Nestadt G, Samuels J, Riddle M, Bienvenu OJ 3rd, Liang KY, LaBuda M, Walkup J, Grados M, Hoehn-Saric R: A family study of obsessivecompulsive disorder.  Archives of General Psychiatry 2000; 57:358-363.

4. Bienvenu OJ, Samuels J, Riddle MA, Hoehn-Saric R, Liang KY, Cullen BA, Grados MA, Nestadt G: The relationship of obsessive-compulsive disorder to possible spectrum disorders: results from a family study.  Biological Psychiatry 2000; 48:287-293.

5. Samuels J, Nestadt G, Bienvenu OJ, Costa PT Jr, Riddle MA, Liang KY, Hoehn-Saric R, Grados MA, Cullen BA: Personality disorders and normal personality dimensions in obsessive-compulsive disorder: results from the Johns Hopkins OCD Family Study. British Journal of Psychiatry 2000; 177:457-462.

6. Nestadt G, Lan T, Samuels J, Riddle M, Bienvenu OJ 3rd, Liang KY, Hoehn-Saric  R, Cullen B, Grados M, Beaty TH, Shugart YY:  Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder (OCD) and heterogeneity by gender. American Journal of Human Genetics 2000; 67:1611-1616.

7. Nestadt G, Samuels J, Riddle MA, Liang KY, Bienvenu OJ, Hoehn-Saric R, Grados M, Cullen B: The relationship between obsessive-compulsive disorder and anxiety and affective disorders: results from the Johns Hopkins OCD Family Study.  Psychological Medicine 2001; 31:481-487.

8. Cullen BA, Samuels JF, Bienvenu OJ, Grados M, Hoehn-Saric R, Hahn J, Liang KY, Wellen D, Dees M, Riddle MA, Nestadt G: Pathological skin picking and obsessive-compulsive disorder. Journal of Nervous and Mental Disease 2001; 189: 193-195.

9. Grados MA, Riddle MA, Samuels J, Liang KY, Hoehn-Saric R, Bienvenu OJ, Walkup JT, Song D, Nestadt G: The familial phenotype of obsessive-compulsive disorder in relation to tic disorders: the Johns Hopkins OCD Family Study. Biological Psychiatry  2001; 50:559-565.

10. Nestadt G, Samuels J, Riddle MA, Bienvenu OJ, Liang KY, Grados MA, Cullen B: Obsessive-compulsive disorder: defining the phenotype. Journal of Clinical  Psychiatry 2002; 63(suppl 6): 5-7.

11. Samuels J, Bienvenu OJ, Riddle MA, Cullen BA, Grados MA, Liang KY, Hoehn-Saric R, Nestadt G: Hoarding in obsessive-compulsive disorder: results from a case-control study. Behavior Research and Therapy 2002; 40:517-528.

12. Nestadt G, Addington A, Samuels J, Liang KY, Bienvenu OJ, Riddle M, Grados M, Hoehn-Saric R, Cullen B: Identification of OCD-related subgroups based on comorbidity.  Biological Psychiatry 2003; 53:914-920.

13. Willour VL, Shugart YY, Samuels J, Grados M, Cullen B, Bienvenu OJ 3rd, Wang Y, Liang KY, Valle D, Hoehn-Saric R, Riddle M, Nestadt G: Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder.  American Journal of Human Genetics 2004; 75:508-513.

14. Hong JP, Samuels J, Bienvenu OJ 3rd, Cannistraro P, Grados M, Riddle MA, Liang KY, Cullen B, Hoehn-Saric R, Nestadt G:  Clinical correlates of  recurrent  major depression in obsessive-compulsive disorder.  Depression and Anxiety 2004; 20:92-97.

15. Shugart YY, Samuels J, Willour L, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J,  Pauls DL, Cullen B, Page J, Rasmussen SA, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Nestadt G: Genome-wide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 15q, 6q, and 1q.  Molecular Psychiatry 2006; 11:763-770.

16. Samuels JF, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy  DL, Grados MA, Pinto A, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Bienvenu OJ 3rd, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G: The OCD Collaborative Genetics Study: methods and sample description. American Journal of Medical Genetics Part B  (Neuropsychiatric Genetics) 2006; 141B(3):201-207

17. Wellen D, Samuels J, Bienvenu OJ, Grados M, Cullen B, Riddle M, Liang KY, Nestadt G: The utility of the Leyton Obsessional Inventory in distinguishing OCD and OCPD. Depression and Anxiety 2006; 24:301-306.

18. Samuels JF, Bienvenu OJ, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Greenberg BD, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G: Hoarding in obsessive- compulsive disorder: results from the OCD Collaborative Genetics Study. Behavior Research and Therapy 2007; 43:673-686.

19. Cullen B, Brown CH, Riddle MA, Grados M, Bienvenu OJ, Willour VL, Hoehn-Saric R, Shugart YY, Liang K-Y, Samuels J, Nestadt G: Factor analysis of  the Yale-Brown Obsessive Compulsive Scale in a family study of obsessive compulsive disorder. Depression and Anxiety 2007; 24:130-138.

20. Hasler G, Pinto A, Greenberg BD, Samuels J, Fyer AJ, Pauls D, Knowles JA, McCracken JT, Piacentini J, Riddle MA, Rauch SL, Rasmussen SA, Willour VL, Grados MA, Cullen B, Bienvenu OJ, Shugart YY, Liang KY, Hoehn-Saric R, Wang Y, Ronquillo J, Nestadt G, Murphy DL: Familiality of  factor analysis-derived YBOCS dimensions in OCD affected sibling pairs from the OCD Collaborative Genetics Study.  Biological Psychiatry 2007; 61:617-625.

21. Samuels J, Shugart YY, Grados MA, Willour VL, Bienvenu OJ, Greenberg BD, Knowles, JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Rasmussen SA, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Nestadt G: Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive compulsive disorder. American Journal of Psychiatry 2007; 164:493-499.

22. Messias E, Eaton W, Bienvenu OJ, Nestadt G, Samuels J: Psychiatrist- ascertained treatment needs for mental disorders in a population-based sample.  Psychiatric Services 2007; 58:373-7.

23. Grados J, Samuels J, Shugart YY, Willour VL, Wang Y, Cullen B, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang K-Y, Riddle MA, Wendland JR, Murphy DL, Nestadt G, Detera-Wadleigh S. Rare plus common SERT variants in obsessive-compulsive disorder. Molecular Psychiatry 2007;12:422-423.

24. Cullen B, Samuels JF, Pinto A, Fyer AJ, McCracken JT, Rauch SL,  Murphy DL, Greenberg BD, Knowles JA, Piacentini J, Bienvenu OJ 3rd, Grados MA, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G:  Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder. Depression and Anxiety 2008; 25:218-224.

25.  Cullen B, Samuels J, Grados M, Landa R, Bienvenu OJ, Liang K-Y, Riddle M, Hoehn-Saric R, Nestadt G: Social and communication difficulties and obsessive-compulsive disorder. Psychopathology 2008; 41:194-200.

26.  Samuels JF, Bienvenu OJ, Grados MA, Cullen B, Riddle MA, Liang KY, Eaton WW, Nestadt G: Prevalence and correlates of hoarding behavior in a  community-based sample. behavior Research and Therapy 2008; 46:836-844.

27.  Pinto A, Greenberg BD, Grados MA, Bienvenu OJ, Samuels JF, Murphy DL, Hasler G, Stout RL, Rauch SL, Shugart YY, Pauls DL, Knowles JA, Fyer AJ, McCracken JT, Piacentini J, Wang Y, Willour VL, Cullen B, Liang K-Y, Hoehn-Saric R, Riddle MA, Rasmussen SA, Nestadt G:  Further  development of YBOCS dimensions in the OCD Collaborative Genetics Study: Symptoms vs categories.  Psychiatry Research 2008; 160:83-93.

28.  Samuels JF, Bienvenu OJ, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Greenberg BD, Knowles JA, Piacentini J, Cullen B,Riddle MA, Rasmussen SA, Pauls DL, Liang K-Y, Hoehn-Saric R, Pulver AE, Nestadt G:  Sex-specific clinical correlates of hoarding in obsessive- compulsive disorder. behavior Research and Therapy 2008; 46:1040-1046.

29.  Liang K-Y, Wang Y, Shugart YY, Grados MA, Fyer AJ, Rauch SL, Murphy DL, McCracken JT, Rasmussen SA, Cullen B, Hoehn-Saric R, Greenberg BD, Pinto A, Knowles JA, Piacentini J, Pauls DL, Bienvenu OJ, Riddle M, Samuels JF, Nestadt G: Evidence for potential relationship between EAAC1 (SLC1A1) and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding. American Journal of Medical Genetics Part B  (Neuropsychiatric Genetics)  2008; 147B:1000-1002.

30.  Wilcox HC, Grados M, Samuels J, Riddle MA, Bienvenu OJ III, Pinto A, Cullen B, Wang Y, Shugart YY, Liang KY, Nestadt G: Association of parental bonding with obsessive compulsive disorder in offspring at high familial risk. Journal of Affective Disorders 2008; 111:31-39.

31.  Wang Y, Samuels JF, Chang YC, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn- Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle MA, Shugart YY, Liang KY, Nestadt G: Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2009; 150B:33-40.

32.  Bienvenu OJ, Wang Y, Shugart YY, Welch JW, Grados MA, Fyer AJ, Rauch SL, McCracken JT, Rasmussen SA, Murphy DL, Cullen B, Valle D, Hoehn- Saric R, Greenberg BD, Pinto A, Knowles JA, Piacentini J, Pauls DL, Liang KY, Riddle MA, Samuels JF, Feng G, Nestadt G. Sapap3 gene appears associated with pathological grooming in humans. American Journal of  Medical  Genetics Part B  (Neuropsychiatric Genetics) 2009; 150B(5):710-20.

33.  Shugart YY, Wang Y, Samuels JF, Chang YC, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn- Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle MA, Liang KY, Nestadt G: A family based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. American Journal of Medical Genetics Part B  (Neuropsychiatric Genetics)  2009; 150B:886-92.

34.  Nestadt G, Di CZ , Riddle MA, Grados MA, Greenberg BD, Fyer AJ,  McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R,  Pinto A, Knowles JA, Piacentini J, Pauls DL, Bienvenu OJ, Wang Y, KY Liang KY, Samuels JF, Bandeen Roche K: Obsessive-compulsive disorder: sub-classification based on comorbidity.  Psychological Medicine 2009; 39:1491-1501.

35.  Wang Y, Admaczyk A, Shugart YY, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle M, Liang KY, Valle D, Wang T, Nestadt G: A screen of SLC1A1 for OCD-related alleles. American Journal of Medical Genetics Part B  (Neuropsychiatric Genetics) 2010; 153B:635-639.

36. Voyiaziakis E, Evgrafov O, Li D, Yoon H-J, Tabares P, Samuels J, Wang Y,  Riddle MA, Grados MA, Bienvenu OJ, Shugart YY, Liang K-Y, Greenberg BD, Rasmussen SA, Murphy DL, Wendland JR, McCracken JT, Piacentini J, Rauch SL, Pauls DL, Nestadt G, Fyer AJ, Knowles JA: Association of SLC6A4 variants with obsessive-compulsive disorder in a large multi-center U.S. family study. Molecular Psychiatry 2011; 16:108-120.

37. Samuels J, Wang Y, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Knowles JA, Piacentin J, Cullen B, Bienvenu OJ, Rasmussen SA, Geller D, Pauls DL, Liang K-Y, Shugart YY, Nestadt G: Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder: American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2011; 156:472-477.

38. Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ 3rd, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piancentini J, Cullen B, Rasmussen SA, Pauls DL, Liang K-Y, Nestadt G, Samuels JF: Separation anxiety disorder in OCD. Depression and Anxiety 2011; 28:256-262.

39. Bienvenu OJ, Samuels JF, Wuyek LA, Liang KY, Wang Y, Grados MA, Cullen BA, Riddle MA, Greenberg BD, Rasmussen SA, Fyer AJ, Pinto A, Rauch SL, Pauls DL, McCracken JT, Piacentini J, Murphy DL, Knowles JA, Nestadt G. Is obsessive-compulsive disorder an anxiety disorder, and what,   if any, are spectrum conditions? A family study perspective. Psychological Medicine 2012; 42:1-13.

40. Blom RM, Samuels JF, Grados MA, Chen Y, Bienvenu OJ, Riddle MA, Liang K-Y, Brandt J, Nestadt G: Cognitive functioning in compulsive hoarding.  Behaviour Research and Therapy 2011; 25:1139-1144.

41. Nestadt G, Wang Y, Grados MA, Riddle MA, Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B,  Piacentini J, Geller D, Pauls D, Bienvenu OJ, Chen Y, Liang KY, Goes FS,  Maher B, Pulver AE, Shugart YY, Valle D, Samuels JF , Chang YC: Homeobox genes in obsessive-compulsive disorder. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2012; 159B:53-60.

42. Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA , Arnold PD, Evans PD, Gamazon ER, Osiecki L, Haddad S, Crane J, Hezel D, Illman C, Mayerfeld C, Konkashbaev A, Liu C, Pluzhnikov A, Tikhomirov A, Edlund CK, Rauch SL, Moessner R, Falkai P, Maier W, Ruhrmann S,   Grabe H-J, Lennertz L, Wagner M, Bellodi L, Cavallini MC, Richter MA,  Cook EH Jr, Kennedy JL, Rosenberg D, Stein DJ, Hemmings SMJ, Lochner C,  Azzam A, Chavira DA, Fournier E, Garrido H, Sheppard B, Umaña P,  Murphy DL, Wendland JR, Veenstra-VanderWeele J, Denys D, Blom R,  Deforce D, Van Nieuwerburgh F, Westenberg HGM, Walitza S, Egberts K,  Renner T, Miguel EC, Cappi C, Hounie AG, do Rosário MC, Sampaio AS, ,37, Vallada H, Nicolini H, Lanzagorta N, Camarena B, Delorme R, Leboyer M,    Pato CN, Pato MT, Voyiaziakis E, Heutink P, Cath , Smit JH, Samuels J,   Cullen B, Fyer AJ, Grados MA, Greenberg BD, McCracken JT, Riddle MA,   Wang Y, Coric V, Leckman JF, Bloch M, Pittenger C, Eapen V, Black DW,   Ophoff RA, Strengman E, Cusi D, Turiel M, Frau FF, Macciardi F, Gibbs JR,  Singleton A, Hardy J, Crenshaw AT, Parkin MA, Mirel DB, Conti DV, Purcell S, Nestadt G, Hanna GL, Jenike MA, Knowles JA, Cox N, Pauls DL: Genome wide association study of OCD. Molecular Psychiatry 2013; 18:788-798.

43.  Stewart SE, Mayerfeld C, Arnold PD, Crane JR, O’Dushlaine C, Fagerness  JA, Scharf JM, Kassam F, Wendland J, Delorme R, Richter MA, Kennedy JL, Veenstra-VanderWeele J, Samuels J, Greenberg BD, McCracken JT, Knowles JA, Fyer AJ, Rauch SL, Nestadt G, Riddle MA, Grados MA, Bienvenu OJ,  Cullen B, Wang Y, Shugart YY, Piacentini J, Rasmussen S, Murphy DL, Cook EH,  Pauls DL, Hanna GL, Mathews CA:. Meta-analysis of association between obsessive-compulsive disorder and the 3’ region of neuronal glutamate transporter SLC1A1. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2013; 162B:367-379.

44. Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio  GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Mesa Restrepo SC, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosàrio MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Valencia Duarte AV, Vallada H, Van Nieuwerburgh F, Veenstra-Vanderweele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ, Scharf JM. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet. 2013 Oct;9(10):e1003864. doi: 10.1371/journal.pgen.1003864. Epub 2013 Oct 24.

45. Samuels J, Shugart YY, Wang Y, Grados M, Bienvenu OJ, Pinto A, Rauch SL,  Greenberg BD, Knowles JA, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Rasmussen SA, Stewart SE, Geller DA, Maher BS, Goes FS, Murphy DL, McCracken JT, Riddle MA, Nestadt G. Clinical correlates and genetic linkage of social and communication difficulties in families with obsessive-compulsive disorder: Results from the OCD Collaborative Genetics Study. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2014; 165:326-336.

46.  McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. Copy number variation in obsessive-compulsive disorder and Tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry 2014; 53:910-919.

47.  Guglielmi V, Vulink NCC, Denys D, Wang Y, Samuels JF, Nestadt G:  Obsessive-compulsive disorder and female reproductive cycle events: results from the OCD and Reproduction Collaborative Study. Depression and  Anxiety 2014; 31:979-87.

48.  Mattheisen M, Samuels JF, Wang Y, Greenberg BD, Fyer AJ,  McCracken JT, Geller DA, Murphy DL, Knowles JA, Grados MA, Riddle MA, Rasmussen SA,  McLaughlin NC, Qin H-D, Cullen BA, Piacentini J, Pauls DL, Bienvenu OJ, Stewart SE, Liang K-Y, Goes FS, Maher B, Pulver AE, Shugart YY, Valle D,  Lange C, Nestadt G. Genome-Wide Association Study in obsessive-compulsive disorder: results from the OCGAS. Molecular Psychiatry 2015; 20:337-244.

49.  Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER,  Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Gallagher P, Gerber G,  Osiecki L, Haddad S, Illmann C, McGrath LM, Anderson K, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Black D, Bloch M, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V,   Cullen B, Cusi D, Davarya S, Delorme R, Denys D, Dion Y, Eapen V, Egberts K,  Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gibbs JR, Gilbert D,  Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SMJ, Herrera LD, Hezel D, Hoekstra PJ,  Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R,   Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL,  Lupoli S, Lyon GJ, Macciardi F, Maier W, Manunta P, Marconi M, Mayerfeld C,  McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Cornejo Ochoa W, Ophoff RA, Pakstis AJ, Pato MT,  Pato CN, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D,  Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B,  Singer HS, Singleton A, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M,  Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Walkup J,   Wang Y, Weiss R, Wendland JR, Westenberg HGM, Yao Y, Hounie AG,  Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D,  Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL,  Conti DV, Arnold PD, Freimer N, Stewart SE, Knowles JA, Cox NJ, Pauls DL. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's Syndrome and obsessive compulsive disorder. American Journal of Psychiatry 2015; 172:82-93.

50.  Samuels J, Grados MA, Riddle MA, Bienvenu OJ, Goes FS, Cullen B, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller D, Murphy DL, Knowles JA, Rasmussen SA, McLaughlin MC, Piancentini J, Pauls DL, Stewart SE, Shugart Y-Y, Maher B, Pulver AE, Nestadt G: Hoarding in children and adolescents with obsessive-compulsive disorder.  Journal of Obsessive-Compulsive and Related Disorders 2014; 3:325-331.

51.  Qin H, Samuels JF, Wang Y, Zhu Y, Grados MA, Riddle MA,        Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Murphy DL, Rasmussen SA, Cullen BA, Piacentini J, Geller D, Stewart SE, Pauls D, Bienvenu OJ, Goes FS, Maher B, Pulver AE, Valle D, Lange C, Mattheisen C, McLaughlin NC,  Liang K-Y, Nurmi EL, Askland KD, Nestadt G, Shugart YY : Whole genome association analysis of treatment response in obsessive-compulsive disorder.  Molecular Psychiatry (in press).

52.  Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA,  Piacentini J, Cullen B, Rasmussen SA, Pauls DL, Nestadt G, Samuels J:  Dependent personality, separation anxiety disorder, and other anxiety disorders in OCD. Personality and Mental Health (in press). DOI 10.1002/pmh.1321

53.  Riddle MA, Maher BS, Wang Y, Grados M, Bienvenu OJ, Goes FS, Cullen B, Murphy DL, Rauch SL, Greenberg BD, Knowles JA, McCracken JT, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Rasmussen SA, Shugart YY, Nestadt G, Samuels J: Obsessive Compulsive Personality Disorder nosology: evidence for two dimensions. Depression and Anxiety (in press).

REVIEW ARTICLES

1.  Samuels J, Nestadt G. Epidemiology and genetics of obsessive-compulsive disorder. International Review of Psychiatry 1997; 9:61-71.

2.  Samuels J. Recent advances in the genetics of obsessive-compulsive disorder. Current Psychiatry Reports 2009; 11:277–282.

4.  Nestadt G, Grados M, Samuels JF. Genetics of OCD. Psychiatric Clinics of North America 2010; 33:141-158.

BOOK CHAPTERS

1.  Costa PT Jr, Samuels J, Bagby M, Daffin L, Norton H. Obsessive-Compulsive Personality Disorder (OCPD): a Review. In: Maj M, Akiskal H, Mezzich J, Okasha A (Eds.), Personality Disorders  (WPA Series, Evidence and Experience in Psychiatry, Vol. 8). West Sussex, UK, Wiley & Sons, 2005, pp. 405-439.

2.  Samuels JF, Grados MA, Planalp E, Bienvenu OJ. Genetic Understanding of OCD and Spectrum Disorders.  In: Steketee G (Editor), Oxford Handbook of  Obsessive Compulsive and Spectrum Disorders (Oxford Library of  Psychology Series). New York, Oxford University Press (in press).

 

 
 
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